Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of cetirizine hydrochloride syrup

A technology for cetirizine hydrochloride and syrup, applied in the field of medicine, can solve problems such as failure to provide cetirizine hydrochloride, and achieve the effects of good taste of preparation, simple preparation process and good stability

Active Publication Date: 2016-09-07
LUNAN BETTER PHARMA
View PDF11 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Searched the existing patented technology and found that the existing technology failed to provide a syrup of cetirizine hydrochloride with good taste and stable properties

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of cetirizine hydrochloride syrup
  • A kind of cetirizine hydrochloride syrup
  • A kind of cetirizine hydrochloride syrup

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] prescription:

[0036]

[0037] Preparation Process:

[0038] Dissolve xanthan gum with part of disodium hydrogen phosphate-citrate buffer solution (pH4.0), add cetirizine hydrochloride, sucrose, aspartame, sodium glutamate and stir to dissolve, add disodium hydrogen phosphate - dilute to full volume with citric acid buffer solution (pH4.0), filter through a microporous membrane, pack and sterilize, ready to use.

Embodiment 2

[0040] prescription:

[0041]

[0042] Preparation Process:

[0043] Dissolve xanthan gum with part of disodium hydrogen phosphate-citrate buffer solution (pH4.0), add cetirizine hydrochloride, sucrose, aspartame, sodium glutamate and stir to dissolve, add disodium hydrogen phosphate - dilute to full volume with citric acid buffer solution (pH4.0), filter through a microporous membrane, pack and sterilize, ready to use.

Embodiment 3

[0045] prescription:

[0046]

[0047] Preparation Process:

[0048] Dissolve xanthan gum with part of disodium hydrogen phosphate-citrate buffer solution (pH4.0), add cetirizine hydrochloride, sucrose, aspartame, sodium glutamate and stir to dissolve, add disodium hydrogen phosphate - dilute to full volume with citric acid buffer solution (pH4.0), filter through a microporous membrane, pack and sterilize, ready to use.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides cetirizine hydrochloride syrup. The syrup comprises cetirizine hydrochloride, sodium glutamate, xanthan gum, saccharose, a pH regulator, a flavoring agent and water, wherein the weight ratio of cetirizine hydrochloride to xanthan gum is 1:(1-10), preferably 1:5; the using amount of sodium glutamate accounts for 0.5-1.0 percent of the total weight of the syrup; the pH regulator is a disodium hydrogen phosphate-citric acid buffer solution; and the flavoring agent is aspartame, steviosin or sodium saccharin. The cetirizine hydrochloride syrup has excellent taste, stable property and simple preparation process.

Description

technical field [0001] The invention belongs to the technical field of medicines, in particular to a cetirizine hydrochloride syrup. Background technique [0002] Cetirizine Hydrochloride (Cetirizine Hydrochloride) is a second-generation antihistamine, the chemical name is (±)-2-[2-[4-[(4-chlorophenyl)benzyl]-1-piperazine Base] ethoxy] acetic acid dihydrochloride, molecular formula: C 21 h 25 ClN 2 o 3 2HCl, molecular weight: 461.82, structural formula as follows: [0003] [0004] Cetirizine hydrochloride is a potent H1 receptor antagonist. It is orally administered into the body and quickly binds to the histamine H1 receptor on the target cell membrane, blocking the activation of target cells by histamine. Cetirizine has no obvious anticholinergic and anti-serotonin effects. In normal doses, it is difficult to pass through the blood-brain barrier. This product can inhibit the transmission of histamine in the early stage of allergic reaction, reduce the migratory ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/10A61K31/495A61K47/12A61K47/04A61K47/36A61K47/18A61P37/08
Inventor 赵志全陈小伟郑华范锋
Owner LUNAN BETTER PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com