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60 results about "Biomimetic membranes" patented technology
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Biomimetic Membranes for Water Purification. Biomimetic membranes have the potential to produce clean water more efficiently than current state-of-the-art reverse osmosis membranes and could provide easier access to cheaper, clean water while lessening demands on the electrical energy production used for desalination.
Moisturizing composition, and preparation method and application thereof
ActiveCN106727164AImprove moisturizing functionRaise the barrierCosmetic preparationsToilet preparationsLoss rateSkin barrier function
The invention relates to a moisturizing composition, and a preparation method and application thereof, which belong to the field of cosmetics. The moisturizing composition is prepared from the following components in parts by weight: 1.0 to 5.0 parts of sodium hyaluronate, 2.0 to 10.0 parts of carboxymethyl deacetyl chitosan, 30.0 to 60.0 parts of dendrobium officinale extract, and 25.0 to 67.0 parts of deionized water. The moisturizing composition can well form a netted natural biomimetic membrane with skin, the sodium hyaluronate performs the water supplementation and moisturizing in the biomimetic membrane, the carboxymethyl deacetyl chitosan forms a biomimetic sterile membrane, so that natural moisturizing factors such as the sodium hyaluronate can be effectively locked, the water loss rate is decreased; and the dendrobium officinale polysaccharide is combined with the natural biomimetic sterile membrane, so that the moisturizing lasting property after long-term use can be further improved, the restoration effect is improved, and the dryness and allergy problems of the skin can be fundamentally solved. The moisturizing composition has multidimensional efficacy such as moisturizing function, restoration function and skin barrier increasing function.
Owner:广西诗琳茉莉生物科技集团有限公司
Biomimetic membranes
InactiveUS7208089B2High strengthNot compromise protein 's natural functionElectrotherapyMicroorganismsElectricityBiomimetic membranes
Biological membrane proteins are incorporated into a co-polymer matrix to produce membranes with a wide variety of functionalities. In one form of the invention, a composite membrane incorporates two different proteins which cooperate to produce electricity from light. In another form, water transport proteins are embedded in a membrane to enable water purification.
Owner:APPL BIOMIMETIC AS
Biomimetic membranes, their production and uses thereof in water purification
InactiveUS20110084026A1Prevent crashPromote fermentationSemi-permeable membranesGeneral water supply conservationLipid formationFiltration
The present invention discloses a water membrane comprising a lipid bilayer supported on a single side thereof on a water permeable dense support layer, this lipid bilayer being composed of one or more lipids and aquaporin proteins are embedded therein, further wherein the water permeable dense support layer is impermeable to the lipids and to the aquaporin proteins. Also are provided a method for the preparation of these membranes and uses thereof in water filtration applications.
Owner:B G NEGEV TECH & APPL LTD
Method for producing a biomimetic membrane, biomimetic membrane and its applications
InactiveUS20040149688A1Avoid erosionImprove diffusivityPaper/cardboard articlesFixed microstructural devicesBiomimetic membranesBiological membrane
The invention concerns a method for producing a biomimetic membrane, a biomimetic membrane and the applications of said membrane. Said biomimetic membrane (10) has one or several through pores (24) and is characterised in that it is formed of at least two different micro-machinable materials one of which forms the wall (23) of said pore(s), whereas the other or others of said materials form(s) the remainder of said membrane. Applications: performing studies on the dynamic and functional properties of biological membranes; manufacture of biocatalysis microsystems and detection or dosing of substances.
Owner:COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Scaffold for composite biomimetic membrane
InactiveUS20110020950A1Highly effective membrane areaHigh areaSemi-permeable membranesMembranesBiomimetic membranesSurface level
Disclosed herein is a membrane scaffold comprising a planar material having a hydrophobic surface and a functional area comprising a plurality of apertures. The apertures have a diameter of from about 80 μm to about 3000 μm and the rims of the apertures comprise bulges extending above and / or below the surface level of the planar material. The membrane scaffold is useful in the preparation of a composite biomimetic membrane wherein functional channel forming molecules have been incorporated in said membrane.
Owner:AQUAPORIN AS
Preparation method for chitosan-based biomimetic membrane material with asymmetric structure
InactiveCN104841021AControllable regulation of degradabilityDegradation controllableSurgeryAcetic anhydrideWater methanol
The invention discloses a preparation method for a chitosan-based biomimetic membrane material with an asymmetric structure, and the preparation method comprises the following steps of dispersing chitosan into acetic acid aqueous solution, adding absolute methanol and acetic anhydride for reacting after the chitosan is completely dissolved, and then, centrifugally removing sediment; dropping in alkaline solidification liquid under stirring condition, and filtering to obtain chitosan microgel; adding the chitosan microgel in glycerin solution, injecting the solution in a mold, and standing and draining water, freeze-drying one part to obtain a chitosan-based porous sponge material, and drying the other part to obtain a chitosan-based dense membrane material; bonding the chitosan-based porous sponge material and the chitosan-based dense membrane material to obtain the chitosan-based biomimetic membrane material with asymmetric structure. The preparation method provided by the invention has the advantages that the preparation technology is simple, the prepared chitosan-based biomimetic membrane material has a porous sponge structure and a dense membrane material structure, the chitosan-based biomimetic membrane material is not curly when encountering water, guiding bone regeneration performance is good, and the chitosan-based biomimetic membrane material is degradable and controllable and can be widely used as a guided bone tissue regeneration membrane material in treatment of the fields such as dental implant, osteoarthritis, bone defect, and the like.
Owner:ZHEJIANG UNIV
Biomimetic Membrane Formed from a Vesicle-Thread Conjugate
ActiveUS20110259815A1Low costReserved functionElectrolytic capacitorsNanoinformaticsBiomimetic membranesCell Membrane Proteins
The present invention relates to a method for producing man-made devices which have the properties and functions of biological membranes and membrane proteins, and to the structure of such devices.Briefly, in one aspect of the invention, natural or genetically engineered proteins are incorporated into a polymeric vesicle that is conjugated to a thread to form a vesicle-thread conjugate. The engineered protein is preferably a transmembrane protein embedded in the wall of the polymeric vesicle. The vesicle-thread conjugate is then formed into a membrane or thin fabric having a wide variety of inherent functionality, including the ability to selectively transport and / or filter compounds between fluids. By selecting proteins with specific properties, membranes can be fabricated with a defined functionality including molecular scale addressability via directed electrostatic, electromagnetic, and chemical forces.
Owner:AQUAZ AS
Moisturizing and repairing composition and epidermis biomimetic membrane liquid crystal complex constructed therefrom
ActiveCN104814881AExert moisturizing and repairing functionHigh affinityCosmetic preparationsToilet preparationsHydroxyprolineCholesterol
The invention belongs to the technical field of daily care products and discloses a moisturizing and repairing composition and an epidermis biomimetic membrane liquid crystal complex constructed therefrom. The core components of the moisturizing and repairing composition and the epidermis biomimetic membrane liquid crystal complex include ceramide, phytosphingosine, cholesterol, lauryl glutamate, squalane, myristyl alcohol, cetostearyl alcohol, arginine, glycine and hydroxyproline. In the invention, by means of combination of various raw materials and through a layered liquid crystal forming mechanism, the special epidermis biomimetic membrane is developed, by which a lamellar liquid crystal body, which likes a keratinocyte intercellular lipid layer, can be formed, so that an effect of protecting skin and improving skin can be achieved.
Owner:HUAANTANG BIOTECH GRP CO LTD
Biomimetic membrane for removing aflatoxins, and preparation method and treatment method of biomimetic membrane
ActiveCN107927528AImprove stabilityExtension of timeLiquid surface applicatorsOn/in organic carrierBiomimetic membranesEnzyme catalysis
The invention provides a biomimetic membrane for removing aflatoxins, and a preparation method and treatment method of the biomimetic membrane. The biomimetic membrane comprises a microporous membrane, a dopamine coating coats the microporous membrane, polyethyleneimine is grafted to the dopamine coating, and enzyme molecules are adsorbed onto the polyethyleneimine. The method comprises the following steps of firstly coating the microporous membrane with poly-dopamine, then grafting the polyethyleneimine, and finally adsorbing the enzyme molecules through the polyethyleneimine. Enzymes adsorbed onto the biomimetic membrane can be unceasingly desorbed and released into feed liquid in the process of performing catalytic degradation on the aflatoxins, so that the polyethyleneimine is exposedto continue adsorbing the aflatoxins until a saturated state is obtained, and the total aflatoxins removing rate is greater than 80%. The adsorbed aflatoxins are eluted with aqueous alkali, so that regeneration and repeated use of the biomimetic membrane are realized, and 50% or above of the eluted aflatoxins can be degraded in the aqueous alkali. The preparation technology of the biomimetic membrane disclosed by the invention is simple, enzyme catalysis, enzyme slow release, membrane adsorption and alkali treatment are combined, and the removal rate of the aflatoxins can be increased.
Owner:INST OF PROCESS ENG CHINESE ACAD OF SCI
Preparation of biomimetic material
InactiveCN101353478AHigh mechanical strengthGood flexibilityOther chemical processesSide chainWater treatment
The invention discloses a preparation method of a biomimetic material, in particular relates to a method for preparing the composition material of poly-aspartic acid or the derivatives, chitosan, lecithin and calcium-phosphate compound. The method first compounds poly-aspartic acid or the derivatives with different side chains, and then makes the poly-aspartic acid or the derivatives with different side chains, chitosan, lecithin, calciferous solution and crosslinking agent mix, react and settle down under a certain temperature and pH value. The obtained product has the properties of biomimetic membrane materials and is an environment-friendly biomimetic material. The material has the function of absorbing heavy metals and some organics, can be used for removing heavy metals, chlorinated hydrocarbon, organic pigment and dye, and can be widely applied to pharmaceutical industry, food industry, printing and dyeing industry, waste water treatment and other fields.
Owner:TIANJIN UNIVERSITY OF TECHNOLOGY
Biomimetic particles and films for pathogen capture and other uses
InactiveUS20100190690A1Improve adsorption capacityMinimize disruptionSurgerySaccharide peptide ingredientsBody contactBiocompatibility Testing
The identification and immobilization of glycosylated molecules having biomimetic properties, more particularly naturally-occurring, tissue-derived, non-immunological glycan sequences or functional equivalents thereof, on solid state surfaces and films or on membranes arising at the interface between non-polar and polar materials is described herein. The biomimetic glycosylated films and particles constructed therefrom have industrial, environmental, diagnostic and / or therapeutic utility in the binding, capture, and / or extraction of pathogens, toxins and / or contaminants, in vivo, in vitro or in situ. The present invention further extends to the use of such biomimetic films and particles for the delivery of other therapeutic molecules as well as in the construction of body contacting devices having enhanced biocompatibility and reduced immunogenicity.
Owner:SPEDDEN RICHARD H
Synthesis of nanotopographic biomimetic membranes for tissue culture, engineering and prosthetics applications
The present invention provide methods for preparing nanostructured membranes. The methods include: providing a substrate with a charged silanized surface; forming a multilayered membrane containing at least two polyelectrolytes; inducing polyelectrolyte phase separation; crosslinking the multilayered membrane; and covalently linking the multilayered membrane to the silanized surface. Methods for fabricating membrane replicas are also disclosed, as well as devices such as cell- and tissue-culture substrates that contain the membranes and membrane replicas. Resulting materials exhibit topographic features and compliance of the extracellular matrix in vivo.
Owner:RGT UNIV OF CALIFORNIA
Making of Organic Nanobiomimetic Memristor and Memcapacitors and its Applications in Dual Sensing of a Biomarker in Neurodegenerative Diseases Thereto
ActiveUS20180088069A1Energy efficiencySave energySolid-state devicesSemiconductor/solid-state device manufacturingCross-linkBiomarker (petroleum)
An organic memristor / memcapacitor device comprises a biomimetic membrane attached on the surface of an electrode forming variable size toroidal matrix cross-linked to derivative cyclodextrin polymers forming cross bars, that facilitate a dual functioning biosensor characteristics which enabled to detecting voltage and current changes of a biomarker β-amyloid (Aβ) in pM concentration that direct linked to Alzheimer's disease and other neurodegenerative diseases under reagent-less, tracer-free and antibody-free conditions in biological fluid specimens.
Owner:CHEN ELLEN T
Biomimetic membrane for cell expansion
InactiveUS20120028275A1Promoting cell attachmentAccelerate cultivationBioreactor/fermenter combinationsBiological substance pretreatmentsCoated membraneCell-Extracellular Matrix
The invention relates to a membrane which can be used for cultivating adherent or suspension cells, in particular adherent cells, wherein said membrane allows for the adhesion and proliferation of the cells due to modification of the membrane surface with a combination of at least one extracellular matrix protein, at least one extracellular matrix (proteo-) glycan, and at least one heparin-binding growth factor. The invention further relates to a method for preparing said modified or coated membrane which can be used for the cultivation of cells, in particular adherent cells, and to methods of using such membrane for the cultivation of cells, in particular adherent cells.
Owner:GAMBRO LUNDIA AB
Biomimetic membranes and uses thereof
InactiveUS20130277307A1General water supply conservationSeawater treatmentEmulsion liquid membraneDesalination
Owner:AQUAPORIN AS
Flow identification nano vesicle used for cell capture, and preparation method and applications thereof
InactiveCN111235103AIncrease local densityEfficient captureCell dissociation methodsBioreactor/fermenter combinationsCell trappingBiomimetic membranes
The invention discloses a flow identification nano vesicle used for cell capture. The nano vesicle is characterized in that the nano vesicle includes a sphere structure formed by natural cell membranes or biomimetic membranes through wrapping; and the interfaces of the membranes are modified with specific recognition molecules through physical, chemical or biological action. A method by using thenano vesicle to capture circulating tumor cells is also provided. A microfluidic chip is provided and modified with the nano vesicle; and a method by using the microfluidic chip to capture the circulating tumor cells is provided as well. Through the using of liquidity-enhanced multivalent strategies, the efficient, selective and mild capturing of the circulating tumor cells can be realized.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
Biomimetic membranes, methods of manufacture and uses thereof
ActiveUS20190276787A1Improve adhesionPeptide/protein ingredientsApparatus sterilizationBiomimetic membranesChemistry
Owner:RGT UNIV OF CALIFORNIA
Schisanlactone E targeted drug delivery system, preparation method and application thereof
ActiveCN113041356AIncrease hemocytin concentrationDecreased hemocycline concentrationOrganic active ingredientsAntipyreticBiomimetic membranesPharmaceutical drug
The invention discloses a schisanlactone E targeted drug delivery system. The system comprises schisanlactone E, Prussian blue nanoparticles, a biomimetic membrane wrapping layer and a hyaluronic acid modification layer. The invention also discloses a preparation method of the targeted drug delivery system. The preparation method comprises the following steps: synthesizing Prussian blue nanoparticles; preparing a biomimetic membrane; preparing Prussian blue loaded schisanlactone E nanoparticles from Prussian blue nanoparticles and schisanlactone E; preparing biological biomimetic membrane coated Prussian blue loaded hemoglobin nanoparticles by using the biomimetic membrane and the Prussian blue loaded schisanlactone E nanoparticles; and performing hyaluronic acid modification to obtain the schisanlactone E targeted drug delivery system. The schisanlactone E targeted drug delivery system can accurately deliver schisanlactone E to the attack part of arthritis so as to prolong the retention time of the drug at the attack part of arthritis and ensure the safety and effectiveness of treatment. Furthermore, the invention further discloses application of the schisanlactone E targeted drug delivery system in preparation of anti-rheumatoid arthritis drugs.
Owner:HUNAN UNIV OF CHINESE MEDICINE
Preparation method of anti-radiation biomimetic membrane
ActiveCN105924687AImprove distributionHigh strengthFilament/thread formingNon-woven fabricsBrickFiltration
The invention discloses a preparation method of an anti-radiation biomimetic membrane. The preparation method of the anti-radiation biomimetic membrane comprises the following steps: sodium-based montmorillonite nano-plates are taken as 'bricks', chitosan molecules are taken as 'mud', the chitosan molecules are absorbed onto the surfaces of the sodium-based montmorillonite nano-plates through electrostatic adsorption and hydrogen-bond interaction so as to form sodium-based montmorillonite and chitosan hybridized nano-plates, lead tungstate nano-particles are directly decorated on the sodium-based montmorillonite and chitosan hybridized nano-plates, and a montmorillonite and chitosan biomimetic laminated structure hybridized membrane containing the lead tungstate nano-particles can be obtained through vacuum filtration and self assembly. The anti-radiation biomimetic membrane prepared by the invention has a pearl mother imitated structure, the lead tungstate is distributed on the biomimetic membrane better, the membrane has the characteristics of relatively high intensity and radiation resistance, and is excellent in toughness, and the preparation method of the membrane is simple and high in efficiency.
Owner:SOUTHWEAT UNIV OF SCI & TECH
Metal lithium negative electrode for in-situ construction of multifunctional biomimetic membrane and preparation method of metal lithium negative electrode
ActiveCN112542564AUniform depositionGrowth inhibitionElectrode manufacturing processesElectrode carriers/collectorsMetallic lithiumSpinning
The invention discloses a metal lithium negative electrode for in-situ construction of a multifunctional biomimetic membrane and a preparation method of the metal lithium negative electrode. The preparation method comprises the following steps of carbonizing a biomass material to obtain biomass carbon, and then introducing an acidic active group to obtain a mixed carbon material, adding the mixedcarbon material and the resin film into a first solvent, and fully mixing to obtain a first mixed solution, adding a second solvent into the first mixed solution and uniformly mixing to obtain a second mixed solution, performing in-situ electrostatic spinning on the second mixed solution on the surface of metal lithium by adopting wet spinning to obtain a biomass biomimetic membrane with a uniformstructure, coating the surface of the biomass biomimetic membrane with a layer of pore-closing agent, and conducting curing processing. Therefore, the biomass composite membrane with controllable distribution and size can induce uniform deposition of lithium ions, reduce the surface current density and inhibit growth of lithium dendrites, so that the cycling stability of the whole electrode material is remarkably improved.
Owner:SICHUAN PANOVASIC TECH
Biomimetic photocatalysis membrane separation assembly for purifying water
InactiveCN101716469AEasy to moveReduce concentration polarizationSemi-permeable membranesWater/sewage treatment by irradiationBiomimetic membranesWater flow
The invention discloses a biomimetic photocatalysis membrane separation assembly for purifying water, belonging to the technical field of membrane separation, photocatalysis materials and water treatment. The invention aims at simulating plant leaf blades and plant morphology, preparing a photocatalysis separation membrane, enabling a membrane assembly to reasonably utilize space, have flexible structure and to be disturbed easily by a water flow and an airflow, reducing precipitation of pollutants on a membrane surface, fully utilizing light and improving the light use rate. The biomimetic photocatalysis membrane separation assembly is characterized in that the biomimetic membrane piece is prepared by utilizing the fractal characteristic of the plant leaf blade, and a biomimetic membraneassembly is assembled by utilizing the branch structures of trees and a biomimetic principle to assembly the bionic membrane and improve light use rate of the assembly; and the flexible structure of the membrane assembly is beneficial to reducing pollutant precipitation by using a disturbance effect of the water flow and the airflow so as to prevent the inactivation of a catalyst. The invention has the advantage of providing a preparation method of the novel biomimetic photocatalysis membrane separation assembly and a method for separating the pollutants in water by utilizing the high-efficiency photocatalysis membrane of the membrane assembly. The invention can be widely applied to photocatalysis to remove pollutants and purify water.
Owner:DALIAN UNIV OF TECH
Preparation method of simulated leather grain surface layer nanofiber biomimetic membrane
ActiveCN112430911AGuaranteed hygienic performanceImprove breathabilityFilament/thread formingTextile/flexible product manufactureFiberPolymer science
The invention provides a preparation method of a simulated leather grain surface layer fiber biomimetic material with good hygienic property. The preparation method comprises the following steps that(1), an electrostatic spinning solution is prepared; (2), split leather is pretreated; and (3), electrostatic spinning is carried out. According to the scheme of the preparation method of the simulated leather grain surface layer nanofiber biomimetic material, a reasonable manufacturing process is adopted, so that the preparation method is suitable for all spinning solutions which can be applied to electrostatic spinning; and by preparing reasonable manufacturing process parameters, nanofibers with stable and reliable quality are obtained, and a dermis grain surface layer structure is simulated.
Owner:QILU UNIV OF TECH
Method for determination of free radical over-oxidative capacity of environment
InactiveCN107192748AEasy to makeLow costMaterial electrochemical variablesSensor arrayOver oxidation
The invention provides a method of manufacturing electrochemical sensor array for evaluation of the free radical over-oxidative capacity of the environment. The method overcomes the shortage in the prior art, provides an electro-chemical sensor array for measuring free radical lipid over-oxidation of the environment and a method which is quick and easy, low in cost, easy to popularize, field applicable and persistent for evaluating the free-radical over-oxidation capacity and durability of the environment. The novelty of the method is that, although the bilayer phospholipid membrane bio-membrane sensor is currently the most active frontier field in biomedicine, the biomimetic membrane electrochemical sensor array and electrochemical method used for the determination of the free radical over-oxidative capacity in field environment cannot make any discoveries.
Owner:YUNNAN MINZU UNIV
Bionic double-layer sustained-release growth factor film as well as preparation method and application thereof
InactiveCN108066818ABind and secureExert biological functionTissue regenerationProsthesisChemistryPositive power
The invention discloses a bionic double-layer sustained-release growth factor film. The bionic double-layer sustained-release growth factor film is characterized by consisting of extracellular matrixes in similar bodies, comprises a positive charge layer and a negative charge layer, and can realize simultaneous sustained release of growth factors with negative power and positive power. The invention further provides a preparation method for the bionic double-layer sustained-release growth factor film, and the preparation method comprises the following steps: (1) preparing the positive charge layer into a glue solution; (2) preparing the negative charge layer into a glue solution; and (3) neutralizing, cleaning and drying, thereby obtaining the bionic double-layer film. The bionic double-layer sustained-release growth factor film is simple to operate, is low in cost, and the growth factors with negative power and positive power can be adsorbed to the positive charge layer and the negative charge power of the bionic film in an electrostatic mode separately, and can released in a sustained mode along with gradual degradation of the bionic double-layer film. The bionic double-layer sustained-release growth factor film overcomes the defects of the prior art, and plays an important role in regenerative medical fields such as tissue repair.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
Composite biomimetic membrane with artificial water channel
PendingCN114728241AEase of mass productionImprove permeabilitySemi-permeable membranesGeneral water supply conservationFiltrationBiomimetic membranes
The present invention relates to the field of biomimetic membranes with artificial water channels, in particular their use in the production and management of drinking water. The invention relates to a biomimetic membrane with an artificial water channel, a synthesis method of the biomimetic membrane and application of the biomimetic membrane in brackish water and seawater desalination, ultrapure water production or pollutant filtration.
Owner:CENT NAT DE LA RECHERCHE SCI +3
Bionic nano material as well as preparation method and application thereof
PendingCN113521297AGood water solubilityImprove resiliencyPowder deliveryOrganic active ingredientsPhysisorptionChlorin e6
The invention discloses a bionic nano material as well as a preparation method and application thereof. The invention relates to a biomimetic nano material which comprises cerium dioxide, polyacrylic acid, chlorin e6, cinobufagin and a biomimetic membrane, the polyacrylic acid is coated on the surface of the cerium dioxide to synthesize the nano material, the cinobufagin and the chlorin e6 are loaded on the surface of the nano material through physical adsorption and chemical bond combination to obtain a nano composite material, the outer layer of the nano composite material is coated with the biomimetic membrane to obtain the biomimetic nano material, and the invention further provides a preparation method which is easy to operate and easy for large-scale production of the biomimetic nano material. The biomimetic nanomaterial disclosed by the invention has relatively good stability, dispersity and safety, is long in oxygen production strategy duration time, can still keep an effective photodynamic killing effect in an oxygen-deficient environment, is beneficial to reducing side effects of chemotherapeutic drugs and enhancing tumor enrichment efficiency of the chemotherapeutic drugs, and is applied to anti-tumor treatment of photodynamic therapy combined with chemotherapy.
Owner:CHANGSHA WANOU CHEM TECH CO LTD
NIR response type biomimetic membrane nano vesicle as well as construction method and application thereof
ActiveCN113559066APossess the function of efficient homology targetingGrowth inhibitionPharmaceutical non-active ingredientsEmulsion deliveryCell membraneLiposome
The invention discloses an NIR response type biomimetic membrane nano vesicle and a construction method and application thereof. The construction method comprises the following steps of S1, collecting tumor cells, and obtaining a tumor cell membrane solution through a freeze thawing method, gradient centrifugation and resuspension in sequence; S2, adopting a solvent diffusion method to obtain a thermosensitive lipid drug delivery system; and S3, mixing the tumor cell membrane solution with a thermosensitive lipid drug delivery system, and performing extruding and filtering by using a liposome extruder to obtain the NIR response type biomimetic membrane nano vesicle. The NIR response type biomimetic cell membrane nano vesicle prepared by the method provided by the invention has a tumor efficient homologous targeting function, further blocks a PD-1 / PD-L1 pathway, reverses a tumor immunosuppression state for a long time, synergistically exerts anti-tumor immune response, and inhibits growth of primary tumors and metastases.
Owner:THE UNIV OF HONG KONG SHENZHEN HOSPITAL +1
Biomimetic photocatalysis membrane separation assembly for purifying water
InactiveCN101716469BFlexible structureUniform light receivingSemi-permeable membranesWater/sewage treatment by irradiationPrecipitationWater treatment
Owner:DALIAN UNIV OF TECH
Making of organic nanobiomimetic memristor and memcapacitors and its applications in dual sensing of a biomarker in neurodegenerative diseases thereto
ActiveUS10684244B2Energy efficiencySave energySolid-state devicesSemiconductor/solid-state device manufacturingAntiendomysial antibodiesBiomimetic membranes
An organic memristor / memcapacitor device comprises a biomimetic membrane attached on the surface of an electrode forming variable size toroidal matrix cross-linked to derivative cyclodextrin polymers forming cross bars, that facilitate a dual functioning biosensor characteristics which enabled to detecting voltage and current changes of a biomarker β-amyloid (Aβ) in pM concentration that direct linked to Alzheimer's disease and other neurodegenerative diseases under reagent-less, tracer-free and antibody-free conditions in biological fluid specimens.
Owner:CHEN ELLEN T
Fabrication of aquaporin-based biomimetic membrane
Methods of fabricating a membrane comprising proteoliposomes having protein water channels are provided herein. The method may include providing a porous substrate, depositing a solution containing proteoliposomes on the porous substrate, and then contacting the porous substrate with an aqueous monomer solution and an organic monomer solution to form a selective layer on the porous substrate embedding the proteoliposomes. The method may include depositing the aqueous monomer solution, then the solution containing the proteoliposomes, then the organic monomer solution, to form the selective layer. The present disclosure also describes the membrane and a system operable to accommodate both methods.
Owner:NANYANG TECH UNIV
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