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115 results about "Acute diarrhea" patented technology

Bifidobacterium possessing characteristic for anti pathogenesis bacterium in intestinal tract and antioxidation, and application

This invention describes a bifidobacterium, i.e., bifidobacterium longum BM358 that can resist intestinal pathogens as well as resist oxidation. The bifidobacterium longum has such properties as high security, outstanding acid and bile resistance, adhesion to intestinal epithelial cells, outstanding intestinal pathogen resistance and oxidation resistance. The bifidobacterium longum can be used to prevent and treat gastritis, gastrelcosis and duodenitis caused by pylorus helicobacteria, and enteritis, acute diarrhea and enterogastric disorder caused by colibacillus and other intestinal pathogens.
Owner:王敖喜 +1

Compositions containing at least one polyol and inulin characterized by reduced tendencies of the at least one polyol to induce acute diarrhea

A composition containing at least one polyol and certain amounts of inulin relative to the at least one polyol, characterized by a reduced tendency of the at least one polyol to induce acute diarrhea. The at least one polyol may be, for example: xylitol, sorbitol, maltitol, mannitol, isomalt, isomaltitol, lactitol, hydrogenated starch hydrolysates (HSH), glycerol, propylene glycol, erythritol, galactitol and combinations thereof. The composition also contains inulin in amounts sufficient to at least partially reduce, or eliminate, the tendency of the polyol to induce acute diarrhea. Foodstuffs, including drinks and beverages, contain said compositions.
Owner:SILVER BARNARD S

Chinese-medicinal composition for treating enterogastric diseases

A Chinese medicine in the form of pill for treating the gastrointestinal diseases, especially the acute diarrhea and intestinal irritable syndrome, is prepared from 10 Chinese-medicinal materials including jujube, musk, rhubarb, Chuan-xiong rhizome, etc. Its preparing process is also disclosed.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Racecadotril dropping pill and preparation thereof

The invention provides a racecadotril pill which is a composition used for curing acute diarrhea. The racecadotril pill takes g or Kg as the unit and adopts the weight ratio that racecadotril to polyethylene glycol (4000 to 10000) to polyoxyethylene (40) stearate is equal to 1: 1: 1 to 1: 3: 3. The invention also relates to a preparation method, which means that pro rata matching -> making melt liquid and / or emulsion and / or suspension by heating for standby -> adjusting the temperature control system of pill machine -> dropping pill and forming -> removing condensing agent and drying. The racecadotril pill has the advantages of high bioavailability, rapid releasing speed and rapid marked effect. The preparation method of racecadotril pill has the advantages of simple production technology, low production cost, non-pollution of production process and high yield.
Owner:YANCHENG SUHAI PHARMA

Fluorescent quantitative PCR primers and kit for detecting novel SADSCoV (swine acute diarrhea syndrome coronavirus)

The invention belongs to the technical field of biological detection and discloses fluorescent quantitative PCR primers and a kit for detecting novel SADSCoV (swine acute diarrhea syndrome coronavirus). The specific primers and probe are designed according to a nucleocapsid protein gene of a conserved sequence of the SADSCoV, and sequences of the primers and the probe are shown as SEQ ID NO:4-6; the SADSCoV can be amplified specifically by the primers and the probe, for real-time fluorescent quantification, fluorescent data can be acquired by monitoring specific binding condition of the probewith PCR amplified fragments in a PCR process in real time, and the SADSCoV is identified according to Cq value. The SADSCoV can be identified rapidly after PCR amplification with the method, the method is high in accuracy and specificity and good in repeatability and can identify the SADSCoV accurately, rapidly and efficiently, and popularization and application in clinical practice are facilitated.
Owner:SOUTH CHINA AGRI UNIV

Traditional Chinese medicine granule for treating infantile diarrhea and preparation method of traditional Chinese medicine particle

The invention discloses a traditional Chinese medicine granule for treating infantile diarrhea and the preparation method of the traditional Chinese medicine particle. The traditional Chinese medicine granule is prepared by the following processes: carrying out water decoction, filtering, concentrating, drying, pelletizing, packing and the like by taking 25 medical materials as raw materials, such as clove, poria cocos, schisandra chinensis, flour-cooked kudzuvine root, fructus evodiae, salt plantain seed, scutellaria baicalensis, rhizoma alismatis, pericarpium arecae, fried Chinese date, fried hawthorn, salvia miltiorrhiza, coptis root, simmered costustoot, dark plum, houttuynia cordata, pericarpium citri reticulatae viride, astragalus mongholicus, baked ginger, bran-fried endothelium corneum gigeriae galli, bran-fried Chinese yam, cinnamon, carbonized sanguisorba root, roasted rhizoma atractylodis macrocephalae and flour-cooked medicine terminalia fruit. The traditional Chinese medicine granule has the effects of tonifying spleen and stopping diarrhea, helping digestion and eliminating indigestion, clearing heat and drying damp, is suitable for various infantile diarrheas including acute diarrhea, chronic diarrhea, infectious diarrhea and non-infectious diarrhea; and the traditional Chinese medicine granule has the characteristics of unique formula, prominent curative effect, less medicine use, quick effect, short treatment course, quick recovery, no toxic and side effects and the like, and is convenient to carry and take. After the traditional Chinese medicine granule for treating the infantile diarrhea is adopted to treat 263 patients, the total effective rate reaches more than 98%.
Owner:刘湘

Bifidobacterium longum AR81 (KCCM-10492) enabling inhibition of rotavirus and active protein separated therefrom

The present invention relates to a novel strain enabling inhibition of rotavirus that is known as a principal cause of acute diarrhea and enteritis in children and in the young animals of cattle, horses, pigs and monkeys, etc, and an active protein also having an anti-rotavirus activity produced from the same. The novel strain of the present invention was named as Bifidobacterium longum AR81 (KCCM-10492). The novel strain of the present invention and the active protein separated from the same can be effectively used for the production of medicine for intestinal disorders and especially for the production of baby goods.
Owner:BIFIDO

Traditional Chinese medicine composition for treating gastrointestinal disease and preparation method thereof

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from elecampane, agilawood, fructus aurantii, sandalwood, rheum officinale, mangnolia officinalis, Muscat and defatted croton seed powder mixed with other medicaments. The invention is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like in clinic.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Swine acute diarrhea syndrome coronavirus primer combination and kit and method thereof

The invention discloses a swine acute diarrhea syndrome coronavirus primer combination and a kit and method thereof. The swine acute diarrhea syndrome coronavirus primer combination and the kit and method thereof aim at providing an SADS (swine acute diarrhea syndrome) detecting primer and method high in sensitivity and specificity. The swine acute diarrhea syndrome coronavirus primer combinationis composed of a forward inner primer of SADS-FIP, a backward inner primer of SADS-BIP, a forward outer primer of SADS-F3, a backward outer primer of SADS-B3, a forward loop primer of SADS-LF and a backward loop primer of SADS-LB. The detecting method of the swine acute diarrhea syndrome coronavirus primer combination comprises 1) extracting RNA (ribonucleic acid) of virus from a sample; 2) takingthe extracted RNA as a template, and establishing an RT-LAMP(reverse transcription-loop-mediated isothermal amplification) system through the RT-LAMP primer combination of SADS to perform RT-LAMP ata constant temperature of 60-65 DEG C; 3) detecting amplification products through a DEAOU-308C thermostatic fluorescence detector. The swine acute diarrhea syndrome coronavirus primer combination andthe kit and method thereof belong to the field of biological detecting technology.
Owner:ZHEJIANG UNIV +1

Preparation method of racecadotril

The invention relates to a preparation method of racemic N-[2-acetyl mercapto) methyl]-1-oxygen-3-phenyl propyl] glycine benzyl ester (racecadotril), which is essentially prepared by amidation reaction of 2-benzyl-3-thio-acetyl propionyl halide and glycine benzyl ester salt or glycine benzyl ester. Compared with the prior art, the invention has short reaction process, high yield. The prepared racecadotril is mainly used for the treatment of acute diarrhea for adults and children.
Owner:SHANDONG QIDU PHARMA

Montmorillonite suspension and preparation method thereof

The invention discloses a montmorillonite suspension for treating acute diarrhea. The montmorillonite suspension is composed of montmorillonite, glucose, a natural polymer suspending agent, sodium benzoate and a proper amount of purified water. The invention also discloses a preparation method of the montmorillonite suspension for treating the acute diarrhea. The method comprises the following steps: putting the montmorillonite, the glucose, the natural polymer suspending agent and the sodium benzoate by proportion into a sealed tank, sufficiently stirring, shaking and uniformly mixing, grinding the mixtures and refining to sieve by a 325-mesh sieve; and adding enough purified water, fully stirring to obtain the suspension, getting a constant volume, homogenizing, sterilizing and packaging. The montmorillonite is processed into the suspension so that the granule is refined, the absorbing force is big, and the protection effect on the gastrointestinal mucous membrane is strong; and the pathogene can be effectively eliminated and the pharmacologic action is rapidly developed.
Owner:赵志坚

One coding gene of rotavirus VP6 protein and its application

The present invention discloses one coding gene of rotavirus VP6 protein and its application, and aims at providing one coding gene of rotavirus VP6 protein with high expression amount in dicotyledonous plant, especially clover, method of producing oral rotavirus vaccine with the coding gene and the obtained oral vaccine. The rotavirus VP6 protein coding gene has one of the following nucleotide sequences: 1. DNA sequence of SEQ ID No. 1 in the sequence list; 2. DNA sequence of SEQ ID No. 2 in the sequence list; 3. the nucleotide sequence capable of hybridizing in high strict condition with the DNA sequence limited by SEQ ID No. 1 or SEQ ID No. 2; and 4. DNA sequence possessing over 80 % homology with the SEQ ID No. 1 or SEQ ID No. 2 limited DNA sequence and high expression amount in dicotyledonous plant. The oral rotavirus vaccine is used in preventing various rotavirus infection caused acute diarrhea of infant and young animal.
Owner:CHINA AGRI UNIV

Sandalwood-containing traditional Chinese medicine for treating gastrointestinal diseases and preparation method thereof

The invention relates to a sandalwood-containing traditional Chinese medicine for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine is prepared by processing ten drugs such as costustoot, sandalwood, immature bitter orange, fructus amomi, rhizoma coptidis or radix scutellariae, mangnolia officinalis or rhizoma atractylodis, muskiness, defatted croton seed powder, Chinese date and ligusticum wallichii and the like, is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like on clinic.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Medicinal cap sule for treating enteric disease and nusosinusitis and preparing method thereof

The invention discloses a drug capsule to cure intestines disease and sinusitis, and the preparing method, using Common Andrographis Herb and Climbing Groundsel Herb as main raw material, associated with micronized silica gel. It is applied to symptoms such as enteritis, colonitis, bacteroidal dysentery and sinusitis, has better curative effect on the patient suffering sinusitis whose course of diseases is short and whose middle nose channel have no rhinopolypus, has good curative effect on the patient suffering from acute diarrhea, acute dysentery and acute enteritis, especially the patient taking other medicine to cause maladjustment of bacteric crowd to produce side-effect. It has functions of cleaning heat and detoxifying, diminishing inflammation and acesodyne, and anti-diarrhoea. It better preserves effective substance in medicinal materials, shelf life up to above two years and having advantages of good stability, accurate curative effect, saving time, low cost, etc.
Owner:江西本真药业有限责任公司

Traditional Chinese medicine composition for treating gastrointestinal disease and preparation method thereof

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from elecampane, pericarpium citri reticulatae viride or rhizoma cyperi, fructus aurantii, sandalwood, rheum officinale, mangnolia officinalis, muscat, defatted croton seed powder, fructus Zizyphi and ligusticum wallichii. The invention is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like in clinic.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Anti-campylobacter jejuni antibodies and uses therefor

Campylobacter jejuni is a leading cause of bacterial food-borne diseases in humans, ranging from acute diarrheal disease to neurological disorders. An isolated or purified antibody or fragment thereof specific to C. jejuni is described. The antibody or fragment thereof binds to a flagellar protein and reduces motility of C. jejuni. The antibody or fragment thereof is derived from a heavy chain IgG variable domain fragment (VHH) of a camelid animal immunized with C. jejuni flagellar protein. A multivalent form, as well as a phage format, of the antibody or fragment thereof is described. Methods of reducing presence of C. jejuni in an animal or an animal environment, methods and formulations for treating C. jejuni infection, and method of detecting C. jejuni are also described.
Owner:NAT RES COUNCIL OF CANADA

Traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared from tens of traditional Chinese herbs of costustoot, agilawood, fructus aurantii, sanders, rheum officinale, mangnolia officinalis, muak, defatted croton seed powder, date and ligusticum wallichii. The traditional Chinese medicine composition is mainly used for treating diseases of acute diarrhea, irritable bowel syndrome and the like in clinic.
Owner:TIANJIN ZHONGXIN PHARMA GRP CO LTD

Costunolide-containing traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof

The invention relates to a costunolide-containing traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared from basic medicines and other medicines, wherein, the basic medicines comprise the following components: costunolide, naringin, santalol, chrysophanol, artificial musk, ligustrazine, croton oil and polysaccharides from Chinese red dates. The traditional Chinese medicine composition is mainly used for clinically treating diseases such as acute diarrhea, irritable bowel syndrome and the like.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Traditional Chinese medicine patch for treating gastrointestinal diseases and preparation method thereof

The invention relates to a traditional Chinese medicine patch for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine patch is prepared from tens of traditional Chinese herbs of costustoot, agilawood, fructus aurantii, sanders, rheum officinale, mangnolia officinalis, muak, defatted croton seed powder, date and ligusticum wallichii. The traditional Chinese medicine patch is mainly used for treating diseases of acute diarrhea, irritable bowel syndrome and the like in clinic.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Rotavirus and ad virus two-in-one detection kit

The invention discloses a dual detection box of rotavirus and adenovirus and comprises test objects and feces diluents; wherein, the test objects consist of chromatographic films and water absorbent materials and comprise a first area, a second area, a third area and a fourth area; the first area comprises an absorbent pad made of water absorbent materials and used for initial sampling contact; the second area comprises latex particles which are coated by monoclonal antibodies of the rotavirus and adenovirus; the third area comprises three lateral parallel chromatographic films which can not be seen with naked eyes, and a first film is provided with a specific anti-adenovirus antibody, and a second film is provided with a specific anti-rotavirus antibody and a third film is a quality control line; the fourth area comprises an absorbent pad made of the water absorbent materials. The detection box is convenient in use and can be used for detecting the acute diarrhea, vomiting, high fever and stomachache which are caused by viral gastroenteritis of adults and infants with less time, labor and materials.
Owner:深圳市惠安生物科技有限公司

Traditional Chinese medicine preparation for treating chronic diarrhea

The invention relate to a traditional Chinese medicine preparation (a traditional Chinese medicine preparation pill) for treating chronic diarrhea, which is prepared from the raw materials of 2-20 parts of amur corktree bark, 2-20 parts of rhizoma coptidis, 2-20 parts of hovenia dulcis (fried with bran), 2-20 parts of officinal magnolia bark (heating with ginger), 10-60 parts of pitted Chinese date, 0.1-0.8 part of rhizoma rehmanniae, 1-10 parts of semen nelumbinis, 1-10 parts of sandalwood, 1-10 parts of rhubarb, 1-10 parts of polygonum multiflorum thunb and 1-10 parts of radix astragali, wherein the semen nelumbinis and the rhizoma rehmanniae are pulverized into fine powder; the radix astragali is pulverized into very fine powder, the other eight drugs, such as rhizoma coptidis, and the like are pulverized into fine powder and uniformly mixed with the semen nelumbinis powder and the rhizoma rehmanniae powder for sieving; a pill is prepared by using water and dried at low temperature; and an oral preparation is prepared by mixing the radix astragali as coating with pharmaceutic adjuvants. The traditional Chinese medicine preparation pill has the characteristics of high efficiency, quick effect, long effect and convenience of oral-taking. Through the clinical observation for many years, the traditional Chinese medicine preparation pill has remarkable treating effect on acute diarrhea, bacillary dysentery and lienteric diarrhea.
Owner:TIANJIN PACIFIC PHARMA

Reagent kit for detecting porcine delta coronaviruses and acute diarrhea syndrome coronaviruses

The invention provides a reagent kit for detecting porcine delta coronaviruses and acute diarrhea syndrome coronaviruses porcine delta coronavirus. According to a primer and probe (SEQ ID NO: 1-6) fordouble real-time fluorescent quantitative PCR detection of the porcine delta coronaviruses and the porcine acute diarrhea syndrome coronaviruses, and a double real-time fluorescent quantitative PCR detection method established based on the primer and the probe, and rapid identification and detection of the two viruses in one reaction can be realized at the same time. The reagent kit can completedetection within 2 hours, has the advantages of quickness, specificity, sensitivity, high flux and the like, and can meet the requirements of quickly identifying and detecting the porcine delta coronaviruses and the porcine acute diarrhea syndrome coronaviruses on a large scale.
Owner:HENAN CENT FOR ANIMAL DISEASE CONTROL & PREVENTION

LAMP primer composition and kit for detecting swine acute diarrhea syndrome coronavirus by using microfluidic chip technology

The invention belongs to the field of nucleic acid detection and diagnosis, and in particular relates to a loop-mediated isothermal amplification (LAMP) primer composition and kit for detecting a swine acute diarrhea syndrome coronavirus (SADS-CoV) by using a microfluidic chip technology. In order to solve the defect of time-consuming, laborious and high-cost detection of a swine acute diarrhea syndrome coronavirus, LAMP primers are designed according to a relatively conservative M gene of the SADS-CoV, after screening is performed, the LAMP primer composition for detecting the swine acute diarrhea syndrome coronavirus is obtained. The invention also provides the kit combining the microfluidic chip technology and an LAMP technology and a detection method of the SADS-CoV by using the kit. The composition and kit are applied to detection of the swine acute diarrhea syndrome coronavirus, and can realize the rapid and immediate detection of the swine acute diarrhea syndrome coronavirus, thereby solving the defect of time-consuming, laborious and high-cost detection of the swine acute diarrhea syndrome coronavirus; and the composition and kit improve the detection sensitivity and specificity, reduce labor and equipment costs, and shorten the detection cycle.
Owner:SOUTH CHINA AGRI UNIV

Gastrointestinal disease-treating traditional Chinese medicine composition containing costustoot and preparation method thereof

The invention relates to a gastrointestinal disease-treating traditional Chinese medicine composition containing costustoot and a preparation method thereof. The traditional Chinese medicine composition is prepared with costustoot, fructus amomi or Chinese eaglewood, bitter orange or immature bitter orange, sandalwood, rhubarb, officinal magnolia bark, musk, defatted croton seed powder, Chinese date, Szechuan lovage rhizome and the like. Clinically, the traditional Chinese medicine composition mainly treats diseases such as acute diarrhea and irritable bowel syndrome.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Medicament for treating acute diarrhea and preparation method for medicament

The invention discloses a medicament for treating acute diarrhea. A preparation method for the medicament comprises the following steps of: decocting chicken gizzard membrane, plantain seed, oriental waterplantain rhizome, pawpaw, figwort flower picrorhiza rhizome and liquoric root which serve as raw materials over slow fire repeatedly, concentrating a liquid medicine into thick paste, and adding the conventional excipient into the thick paste to prepare clinically acceptable tablets, capsules, pills, granules, powder, injection or paste. The medicament can treat all types of acute diarrhea.
Owner:王永红

Application of traditional Chinese medicinal composition in preparation of medicine for treating diarrhea

The invention provides application of a traditional Chinese medicinal composition in the preparation of a medicine for treating diarrhea. The medicine is prepared from the following raw materials (byweight): 120-360 parts of Astragalus membranaceus, 100-300 parts of ligustrum lucidum ait, 30-95 parts of ginseng, 30-95 parts of lucid ganoderma, 65-195 parts of curcuma zedoary, 30-90 parts of bighead atractylodes rhizome, 65-195 parts of scutellaria barbata, 120-360 parts of gynostemma pentaphyllum, 30-95 parts of Poria cocos, 15-45 parts of endothelium corneum gigeriae galli, 65-195 parts of indian mockstrawberry herb, 65-195 parts of solanum lyratum, 65-195 parts of herba artemisiae scopariae, 65-195 parts of radix cynanchi panicullati, 10-30 parts of ground beeltle, and 65-195 parts of Hedyotis diffusa. The diarrhea treated by the medicine is acute diarrhea, chronic diarrhea and diarrhea caused by tumor chemotherapy.
Owner:HEBEI YILING MEDICINE INST

Double-antibody sandwich ELISA kit for detecting porcine acute diarrhea syndrome coronavirus

The invention belongs to the technical field of biology, and particularly relates to a double-antibody sandwich ELISA kit for detecting porcine acute diarrhea syndrome coronavirus. The double-antibody sandwich ELISA kit for detecting the porcine acute diarrhea syndrome coronavirus comprises an ELISA plate coated with a rabbit anti-SADS-CoV N protein polyclonal antibody, and an HRP (horse radish peroxidase) labeled mouse anti-SADS-CoV N protein monoclonal antibody. The kit further comprises an enzyme-labeled secondary antibody, a confining liquid, a diluent, a washing liquid, a developing liquid and a stop solution. The double-antibody sandwich ELISA kit established by the invention has relatively good specificity, sensitivity and intra-batch and inter-batch repeatability. The lowest virus detection amount of the kit is 10-4.42TCID50/0.1 mL, the kit does not react with PEDV, TGEV and PDCoV, and the intra-batch and inter-batch repeated variable coefficient is less than 10%. Compared with an RT-PCR (Reverse Transcription-Polymerase Chain Reaction) method, the detection coincidence rate of the double-antibody sandwich ELISA kit disclosed by the invention is 93.93%. The SADS-CoV antigen double-antibody sandwich ELISA detection method established by the invention has good sensitivity, specificity and repeatability, and can be used for clinical detection of SADS-CoV.
Owner:LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI +1
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