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Application of traditional Chinese medicinal composition in preparation of medicine for treating diarrhea

A composition and drug technology, applied in the direction of drug combination, medical raw materials derived from arthropods, pharmaceutical formulations, etc., can solve the problems of untreated diarrhea, small intestinal malabsorption, secondary small intestinal malabsorption, etc., and achieve compatibility Reasonable, less adverse effects

Inactive Publication Date: 2020-03-03
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(4) Small intestinal malabsorption ①Primary small intestinal malabsorption; ②Secondary small intestinal malabsorption
However, the above treatment methods can only temporarily relieve the symptoms of diarrhea, and do not fundamentally treat diarrhea. Therefore, there is an urgent need for a drug that treats both symptoms and root causes and effectively treats diarrhea.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039]The formula of raw materials is: Astragalus 250g, Ligustrum lucidum 200g, Ginseng 65g, Ganoderma lucidum 65g, Curcuma 132g, Fried Atractylodes 64g, Banzhilian 128g, Gynostemma 256g, Poria cocos 65g, Gallus chinensis 30g, Snakeberry 128g, Baiying 128g, Yin Chen 128g, Xu Changqing 128g, Wood Beetle 20g, Hedyotis diffusa 128g.

[0040] The preparation method is:

[0041] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0042] (2) For ginseng and Ligustrum lucidum, add 8 times the amount of 70% ethanol for reflux extraction twice, the first time for 3 hours, and the second time for 2 hours, combine the extracts, recover the ethanol until there is no alcohol smell, and the filtrate and ginseng, female Residues of chastity seeds for use;

[0043] (3) Curcuma, Atractylodes Rhizome (stir-fried), and Xu Changqing were combined to extract the volatile oil, the oil extraction time was 8 hours, the volatile oil was collecte...

Embodiment 2

[0049] The formula of raw materials is: Astragalus 360g, Ligustrum lucidum 100g, Ginseng 95g, Ganoderma lucidum 30g, Curcuma 195g, Fried Atractylodes macrocephala 30g, Scutellaria barbata 195g, Gynostemma 120g, Poria 95g, Gallus gallinaceae 15g, Snakeberry 195g, Baiying 65g, Yin Chen 195g, Xu Changqing 65g, Wood Beetle 30g, Hedyotis diffusa 65g.

[0050] The preparation method is:

[0051] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0052] (2), ginseng, Ligustrum lucidum, add 6 times the amount of 90% ethanol to reflux and extract for 4 hours, recover the ethanol from the extract until there is no alcohol smell, and the filtrate and ginseng, Ligustrum lucidum residues are for subsequent use;

[0053] (3) Merge Curcuma, Atractylodes Rhizoma Atractylodes Rhizome (stir-fried), and Xu Changqing, add 4 times the amount of water to extract the volatile oil, the oil extraction time is 10 hours, collect the volatile oil i...

Embodiment 3

[0059] The formula of raw materials is: Astragalus 120g, Ligustrum lucidum 300g, Ginseng 30g, Ganoderma lucidum 95g, Curcuma 65g, Atractylodes rhizome 90g, Scutellaria barbata 65g, Jiaogulan 360g, Poria cocos 30g, Gallus chinensis 45g, Snakeberry 65g, Baiying 195g, Yin Chen 65g, Xu Changqing 195g, wood beetle 10g, Hedyotis diffusa 195g.

[0060] The preparation method is:

[0061] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0062] (2) For ginseng and Ligustrum lucidum, add 10 times the amount of 50% ethanol to reflux and extract twice, the first time for 3 hours, and the second time for 2 hours, combine the extracts, recover the ethanol until there is no alcohol smell, and the filtrate and ginseng, female Residues of chastity seeds for use;

[0063] (3) Merge Curcuma, Atractylodes Rhizoma Atractylodes Rhizome, and Xu Changqing, add 10 times the amount of water to extract the volatile oil, the oil extraction time ...

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Abstract

The invention provides application of a traditional Chinese medicinal composition in the preparation of a medicine for treating diarrhea. The medicine is prepared from the following raw materials (byweight): 120-360 parts of Astragalus membranaceus, 100-300 parts of ligustrum lucidum ait, 30-95 parts of ginseng, 30-95 parts of lucid ganoderma, 65-195 parts of curcuma zedoary, 30-90 parts of bighead atractylodes rhizome, 65-195 parts of scutellaria barbata, 120-360 parts of gynostemma pentaphyllum, 30-95 parts of Poria cocos, 15-45 parts of endothelium corneum gigeriae galli, 65-195 parts of indian mockstrawberry herb, 65-195 parts of solanum lyratum, 65-195 parts of herba artemisiae scopariae, 65-195 parts of radix cynanchi panicullati, 10-30 parts of ground beeltle, and 65-195 parts of Hedyotis diffusa. The diarrhea treated by the medicine is acute diarrhea, chronic diarrhea and diarrhea caused by tumor chemotherapy.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in preparing medicine for treating diarrhea. Background technique [0002] Diarrhea refers to the frequency of defecation significantly exceeding the usual habit, thin fecal matter, increased water content, daily defecation volume exceeding 200g, or containing undigested food or pus, blood, and mucus. Diarrhea is often accompanied by symptoms such as urgency to defecate, anal discomfort, and incontinence. Normal people have about 9L of liquid entering the gastrointestinal tract every day, and through the absorption of water by the intestine, the water in the final feces is only about 100-200ml. If the amount of fluid entering the colon exceeds the absorptive capacity of the colon or (and) the absorptive capacity of the colon decreases, it will lead to an increase in the excretion of wat...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/12A61K35/57A61K35/64
CPCA61K36/481A61K36/638A61K36/258A61K36/074A61K36/9066A61K36/284A61K36/539A61K36/424A61K36/076A61K35/57A61K36/73A61K36/81A61K36/282A61K36/27A61K35/64A61K36/748A61P1/12A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 何双凤张喜芬杨立波祁飞
Owner HEBEI YILING MEDICINE INST
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