The invention provides a novel stilbene derivative. The novel stilbene derivative is a compound with a general formula I or general formula II shown as the specification, or is an acceptable salt formed by the compound with the general formula I or general formula II and an inorganic acid or organic acid. Specifically, in the general formula I or general formula II, the atom represented by X is hydrogen atom or halogen atom, the substituent group represented by R is C1-C6 alkyl, 1-6 membered heteroalkyl, C2-C4 alkenyl, C2-C4 alkynyl, C3-C6 cycloalkyl, substituent C3-C6 cycloalkyl, 3-6 membered heterocycloalkyl, substituent 3-6 membered heterocycloalkyl, 5-18 membered aryl, substituent 5-18 membered aryl, 5-18 membered heteroaryl, and substituent 5-18 membered heteroaryl. The novel stilbene derivative has neurogenesis activity and low nerve cell toxicity.