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'Xianlinggubao' new preparation, its preparing method and application

A technology of Xianling Gubao and Psoraleae, which is used in bone diseases, pharmaceutical formulations, and medical preparations containing active ingredients, etc., to achieve the effects of finished product hygiene quality assurance, finished product quality stability, and rapid disintegration.

Inactive Publication Date: 2005-07-06
叶耀良
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Research on the use of Xianling Gubao to prepare new drugs for the treatment of senile dementia is basically blank

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0154] Embodiment 1: the preparation of medicinal material extract

[0155] Dipsacus, Salvia miltiorrhiza, and psoraleae are crushed into 80-mesh fine powder, and the other three ingredients such as epimedium are decocted in water three times, each time for 1 hour, and the decoctions are combined, concentrated to a thick paste with a relative density of 1.35 (30°C), and added The above-mentioned medicinal materials are finely powdered, mixed evenly; dried and pulverized into 80-mesh fine powders, and the medicinal material extracts for preparing dispersible tablets or soft capsules are obtained.

Embodiment 2

[0156] Embodiment 2: the preparation of medicinal material extract

[0157]Dipsacus, Salvia miltiorrhiza, and psoraleae were crushed into 160-mesh fine powder, and the rest of Epimedium and other three flavors were decocted in water three times, each time for 1 hour, and the decoctions were combined, concentrated to a thick paste with a relative density of 1.38 (30°C), and added The above medicinal materials are finely powdered, mixed evenly; dried and pulverized into 160-mesh fine powders to obtain medicinal material extracts for preparing dispersible tablets or soft capsules.

Embodiment 3

[0158] Embodiment 3: the preparation of medicinal material extract

[0159] Dipsacus, Danshen, and psoralen are crushed into 120-mesh fine powder, and the remaining epimedium and other three flavors are decocted in water three times, each time for 1 hour, and the decoctions are combined, concentrated to a thick paste with a relative density of 1.36 (30°C), and added The above medicinal materials are finely powdered, mixed evenly; dried and pulverized into fine powders of 120 mesh, and the medicinal material extracts for preparing dispersible tablets or soft capsules are obtained.

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Abstract

The invention discloses a compound traditional Chinese medicinal extract, which comprises (by weight ratio) epimeddium 1167, dipsacus root 167, root of red rooted saliva 83, anemarrhena rhizome 83, psoralea fruit 83, dried rehmannia root 83, and right amount of pharmaceutically acceptable adjuvant or base material. The compound can be prepared into the dosage form of soft capsule, emulsifying tablet and dressed dispersing tablet, which can be used for treating women's climacteric osteoporosis and senile dementia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation-Xianling Gubao new preparation, its preparation method and application. technical background [0002] Xianling Gubao is used to treat osteoporosis caused by liver and kidney deficiency and blood stasis blocking collaterals. It has the functions of nourishing liver and kidney, promoting blood circulation and dredging collaterals, and strengthening muscles and bones. It is easy to absorb moisture, and the requirements for capsule packaging are strict. Medicines are easy to absorb moisture and have a short validity period. In the original preparation process, only the fine powder of crude drug and the extract of medicinal material were mixed and granulated, and no pharmaceutical excipients were added to help the human body to absorb for the purpose of improving bioavailability and drug efficacy. The original capsule is 0.5g per capsule, and the capsule is relatively large, which...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61P19/10
Inventor 叶耀良廖志钟
Owner 叶耀良
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