52results about How to "Loss of stability" patented technology

Surgical repairs of torn or ruptured tendons and ligaments are made by re-fastening the torn or ruptured tendon or ligament with a biocompatible or bioabsorbable hook-and-loop fastener.

The present invention features a method of making hydrous zirconium oxide having desirable properties, including resistance to moisture content, predetermined particle size, and developed porosity and surface area. The inventive material is suitable for use as an ion exchanger, a catalyst and a catalyst support. The process comprises providing a liquid comprising a zirconium compound and an alkali metal-containing reagent. The alkali metal-containing reagent may comprise a compound selected from the group consisting of MOH-M2SO4, MOH-M3PO4, and combinations thereof, where M is at least one of Li, Na and K. The zirconium compound may be treated with the alkali metal-containing reagent effective to form a mixture which achieves an uptake of alkali metal in an amount ranging from 0.5 to 2.5 meq / g. The mixture is reacted to form the hydrous zirconium oxide. A molar ratio of SO4 / Zr and PO4 / Zr in the mixture may range from 0.2-0.7:1. The mixture may be heated at a temperature ranging from 80 to 150° C. to produce a reaction product. The reaction product may be treated with acid having a pH ranging from 4 to 8 at a temperature ranging from 20 to 60° C. to form the hydrous zirconium oxide. Also featured is a method of making hydrous hafnium oxide. The inventive hydrous zirconium oxide and hydrous hafnium oxide are characterized by at least one of the following: stability against moisture loss, a particular surface area, a particular pore size distribution, an affinity towards anions including at least one of PO4, HPO4, H2PO4, AsO4, HAsO4, H2AsO4 and AsO3, oxoanions of Cr, Se, B, Mo,and W, and / or resistance against poisoning by SiO3 and SO4.

This present invention concerns a cover layer that is impermeable to the active substances and / or a removable protective layer of a transdermal therapeutic system, comprising a thermoplastic film which either directly contains the absorbing agents and channel-forming agents or is coated with a polymer support (thermoplast) containing these substances. The polymer support can either be applied over the entire surface of the film or in patterns, directly during production. The thermoplastic film that is used and the polymer support can be made from either the same or different materials.

The present invention relates to compositions having bioactive transfer proteins in stable carrier systems. Such systems are above all suitable for influencing / changing lipid cell structures by means of improved lipid exchange, while at the same time having great stability. In this connection, not only transfer proteins and lipid components, but also protective colloids are used, by means of which an impairment of the transfer effect of the proteins and a loss of stability can be avoided. The compositions are suitable for external topical use for cleansing, care, dermatological and / or therapeutic treatment of the skin, hair, or mucous membranes.

Presently disclosed are methods and systems for detecting and diagnosing a coolant leak of an engine. A method may include diagnosing a coolant leak of the engine based on a low frequency pressure response of a measured engine coolant pressure. A vehicle system is also disclosed, including an engine, a coolant system operatively connected to the engine. The coolant system includes a coolant reserve and a coolant pump between the engine and the coolant reserve. The vehicle also includes a coolant pressure sensor to measure coolant pressure, and a controller configured to measure an engine coolant pressure and diagnose a coolant leak of the coolant system based on a low frequency pressure response of the measured engine coolant pressure.

The disclosure relates to a packaging laminate for a retortable packaging container comprising a core layer (11), outer, liquid-tight coatings (12 and 13) and a gas barrier (14) disposed between the one coating (12) and the core layer (11). Between the gas barrier (14) and the core layer (11), there is a layer (16) of a lamination or sealing agent of such a nature that the lamination or sealing agent has a melting point which is higher than the maximum temperature to which the retortable packaging container is to be subjected during a normal heat treatment in a retort. The lamination or sealing agent in the layer (16) may, for example, be a polypropylene with a melting point of above 130° C.

A magnetoresistance sensor structure includes a magnetoresistance sensor having a sensor surface plane and having a free layer. An upper antiferromagnetic layer overlies at least a portion of the free layer, and an upper ferromagnetic layer overlies and contacts at least a portion of the upper antiferromagnetic layer on a contact face lying parallel to the sensor surface plane, so that the upper antiferromagnetic layer lies between the upper ferromagnetic layer and the free layer. The magnetoresistance sensor may be a giant magnetoresistance sensor or a tunnel magnetoresistance sensor.

Methods of chemically cross-linking antioxidant-stabilized polymeric material are provided. In one example embodiment, peroxide cross-linking can be used to improve wear resistance and the addition of antioxidant can be used to improve oxidation resistance of ultra-high molecular weight polyethylene. A balance between the amounts of peroxide(s) and antioxidant(s) in the polymeric material can ensure that enough cross-linking is achieved for wear reduction and that enough antioxidant is incorporated for improved long-term oxidative stability. In one example embodiment, peroxide(s) can be diffused into a consolidated polymeric material for cross-linking. In another embodiment, polymeric material is consolidated with a vinyl silane, an antioxidant, and a free radical initiator, and the consolidated polymeric material is contacted with water thereby forming an oxidation resistant, cross-linked polymeric material. Such materials can be used in orthopedic applications such as bearing surfaces in total joint implants, including total hips, total knees, total shoulders, and other total joints.

Disclosed herein is a resistive switching device having an amorphous layer comprised of an insulating silicon-containing material and a conducting material. The amorphous layer may be disposed between two or more electrodes and be capable of switching between at least two resistance states. Circuits and memory devices including resistive switching devices are also disclosed, and a composition of matter involving an insulating silicon-containing material and a conducting material comprising between 5 and 40 percent by molar percentage of the composition is disclosed herein as well. Also disclosed herein are methods for switching the resistance of an amorphous material.

The invention provides an air cleaning agent containing a catalytic agent, and relates to the technical field of environment-friendly material air cleaning. In order to solve the technical problems that an existing air cleaning agent containing a photocatalyst on the market has a single function and poor in weather fastness, cannot achieve purification or freshness for a long time, and is low in cleaning efficiency, the air cleaning agent containing the catalytic agent is prepared, the air cleaning agent adopts the catalytic agent as a main purification object, natural plant components and other auxiliaries are adopted, the air cleaning agent is prepared through the reasonable proportion, use is safe and convenient, the performance of the components are brought into full play and utilized,photocatalyst particles have the good weather fastness and can have the maximum purification effect in actual application, formaldehyde and other hazardous gas in air can be effectively removed, andthe deodorization, sterilization and anti-fouling performance can be achieved.

In one aspect, a method for detecting and diagnosing a coolant leak of an engine may include diagnosing a coolant leak of the engine based on a low frequency pressure response of a measured engine coolant pressure. In another aspect, an engine system (e.g., for a vehicle) includes an engine and a coolant system operatively connected to the engine. The coolant system includes a coolant reserve and a coolant pump between the engine and the coolant reserve. The engine system also includes a coolant pressure sensor to measure coolant pressure, and a controller configured to measure an engine coolant pressure and diagnose a coolant leak of the coolant system based on a low frequency pressure response of the measured engine coolant pressure.

Internal polar and ionizable groups are essential for enzymatic catalysis, proton transport, redox reactions, and many other functional properties of proteins. To engineer novel enzymes or to modify the function of existing ones, and to build switches that can be used to modify the stability of proteins in response to changes in pH, it is necessary to introduce polar or ionizable groups or to modify the properties of existing ones. However, internal polar and ionizable groups usually destabilize proteins. The disclosure provides new methods that allow the introduction of polar and ionizable groups into the interior of proteins, as well as new methods for improving the accuracy of pKa of an internal amino acid of a protein, and methods for mapping the folding free energy landscape of a protein.

The invention relates to a method for transforming a sterile line of Chinese kale by utilizing vernalization and generation adding. The method comprises the following steps of: carrying out hybridization by taking a male sterile line of broccoli cytoplast as a female parent and a selfing line of the Chinese kale as a male parent, so as to obtain hybridized seeds; after the hybridized seeds are planted in summer, carrying out vernalization on plants, and meanwhile, selecting the sterile plants by utilizing pollen microscopic examination or single-plant bagging selfing; and taking the selfing line of the Chinese kale as a recurrent parent, carrying out 3-5-generation backcross with the recurrent parent and the sterile plants, so as to obtain the male sterile line of Chinese kale cytoplast. According to the method, the sterile line of the Chinese kale is transformed by utilizing the male sterile line of broccoli cytoplast, biological characters of the sterile line of the Chinese kale are stable, stamens degenerate, petals and pistils develop normally, nectaries develop well, and seed pods develop normally; the sterile line can be subjected to generation adding propagation under a normal growth condition of the plants, the transformation process is accelerated, the procedures are simplified, the cost is saved, and the purity of the Chinese kale can be improved.

The invention discloses a gate drive circuit and a display device. The gate drive circuit disclosed by the invention comprises a first pre-charging module for charging a first node according to a starting signal; a second pre-charging module used for discharging the second node according to the transmission signal; a first bootstrap module which is connected with the first node and is used for generating and outputting a current-stage transmission signal and a current-stage driving signal according to a first clock signal; a second bootstrap module used for bootstrapping the second node according to the second low-level signal; a first pull-down and stability maintaining module which stabilizes the signal of the first node and the signal of the bootstrap module according to the third clock signal; and a second pull-down and stability maintenance module which is respectively connected with the first low-level signal input end, the second node and the bootstrap module, and stabilizes the bootstrap module according to the first low-level signal. According to the gate drive circuit and the display device disclosed by the invention, the bootstrap module and the pull-down and stability maintaining module are designed, and the gate drive circuit can be suitable for the IGZO process.

The invention discloses a flocculation reaction framed bent device equipped with flexibly-connected impellers. The device comprises framed bents composed of a plurality of lattice bars which are parallel to each other. The framed bents are fixed by a framework. A plurality of flexibly-connected impellers are installed on each lattice bar. Each impeller is composed of a main shaft, a wheel hub and blades. The blades and the wheel hub are connected through springs. Under the impact of current, blades drive the wheel hub to rotate around the main shaft. The framed bents are installed in pairs. The lattice bars on upper and lower framed bents are arranged in a staggered pattern. Impellers on each framed bents are arranged side by side. That is to say, the maximum rotation radiuses of adjacent impellers tangent to each other, and the installation point of each impeller on the lower framed bent is right facing the central gap in the middle of four impellers on the upper framed bent. When current flows through the impellers, the impellers rotate so as to guarantee turbulent fluctuation performance of flocculation. When the flow increases, the rotation radius of the impellers will be reduced under the impact force of current, flow area is increased, and flow velocity is reduced. Thus, head loss is decreased, and it is ensured that head loss is basically stable when the flow increases.

Disclosed herein is a resistive switching device having an amorphous layer comprised of an insulating silicon-containing material and a conducting material. The amorphous layer may be disposed between two or more electrodes and be capable of switching between at least two resistance states. Circuits and memory devices including resistive switching devices are also disclosed, and a composition of matter involving an insulating silicon-containing material and a conducting material comprising between 5 and 40 percent by molar percentage of the composition is disclosed herein as well. Also disclosed herein are methods for switching the resistance of an amorphous material.

A fuel injection valve having a valve retaining body (1), which has a longitudinal axis (2) and in which a central spring chamber (5) is embodied. In this spring chamber (5), a closing spring (6) is disposed, which transmits a closing force to a valve member (30), which valve member (30) cooperates with a valve seat (32) for controlling at least one injection opening (36). In the wall of the spring chamber (5), an inlet conduit (3) extends parallel to the longitudinal axis (2) of the valve retaining body (1), and by way of this conduit, fuel at high pressure can be delivered to the at least one injection opening (36). The cross section of the inlet conduit (3) has a greater length in the circumferential direction than in the radial direction, so that the wall region between the inlet conduit (3) and the spring chamber (5), or the outer jacket face of the valve retaining body (1), is larger than in the case of an inlet conduit (3) with the same size of cross-sectional area and a circular cross-sectional contour (FIG. 1).

Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.

The present invention relates to a method for electronically regulating brake force distribution to the front axle and the rear axle of a motor vehicle (EBV control), wherein the rotational behavior of the vehicle wheels is determined, compared with the vehicle speed or vehicle reference speed and / or with the changes of these variables, and evaluated to limit the slip on the rear-wheel brakes by modulating the braking pressure. The brake force distribution is controlled in dependence on the sum signals obtained by addition of acceleration values determined on each individual rear wheel and / or by addition of slip values determined on each individual rear wheel. It is particularly arranged for to weight the sum signals with variable sum factors and evaluate them as a criterion for triggering the EBV control (so-called EBV plus control).

A fuel injection valve having a valve retaining body, which has a longitudinal axis and in which a central spring chamber is embodied. In this spring chamber, a closing spring is disposed, which transmits a closing force to a valve member, which valve member cooperates with a valve seat for controlling at least one injection opening. In the wall of the spring chamber, an inlet conduit extends parallel to the longitudinal axis of the valve retaining body, and by way of this conduit, fuel at high pressure can be delivered to the at least one injection opening. The cross section of the inlet conduit has a greater length in the circumferential direction than in the radial direction, so that the wall region between the inlet conduit and the spring chamber, or the outer jacket face of the valve retaining body, is larger than in the case of an inlet conduit with the same size of cross-sectional area and a circular cross-sectional contour.

A stand-up paddleboard (SUP) may be configured with a non-retentive binding system to secure a user's foot positioning. In one example, the binding system may include pockets formed from panels extending continuously along edges of the paddleboard, and straps to provide tension on the pockets, to reduce a likelihood of undesired sliding of the user's feet. The pockets of the binding system may allow the user to reposition the user's feet to multiple secured footholds within the binding system, thereby allowing the user's stance and balance to be maintained.

A foot orthotic for golf that provides solid stability and encourages proper foot bracing and release during the golf swing. The orthotic having a semi-rigid shell, compliant top cover, anti-skid forefoot pad and a heel post. The heel post having a short medial edge to encourage proper bracing and release and an extended lateral edge to resist foot rolling or supination during the golf swing.

Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.

The invention discloses an aerial work safeguard device which comprises a protective basket arranged on the side face of a suspension transverse beam and a movable framework. The movable framework comprises side edge beams arranged in the direction of the suspension transverse beam; the side edge beams are provided with a mobile power mechanism; end beams are arranged at the two ends of the side edge beams; the two ends of the end beams are connected with the protective basket; the protective basket comprises stand columns; bottom fences are connected with the lower ends of the stand columns; reinforcing fences are arranged among the bottom fences; and a bottom board is arranged on the upper side of the bottom fences and the reinforcing fences. Based on the scheme, it can be learnt that the aerial work safeguard device has the beneficial effects that the structure is simple, design is reasonable, construction safety is provided, constructors have supporting points during construction, and therefore the construction precision and efficiency are improved.

The present invention relates to a composition comprising: (a) a source of sulfite; and (b) a lipase variant of a parent lipase, wherein one or more amino acids in the parent lipase within 20 angstrom (Å) of a cysteine bridge are replaced with a more negatively charged amino acid.

The invention discloses a method for reinforcing grafted diene rubber by an in-situ sol-gel method. The method comprises the following steps of: adding vinyl siloxanes and benzoyl peroxide into diene rubber latex, reacting for 2 to 6h at the temperature of between 68 and 80 DEG C to obtain vinyl siloxanes grafted and modified diene rubber latex, and adding tetraethoxysilane into the vinyl siloxanes grafted and modified diene rubber latex at the temperature of between 68 and 80 DEG C and performing sol-gel reaction to obtain in-situ reinforced butadiene styrene rubber. The silica-reinforced rubber prepared by the method has higher pure rubber and vulcanized rubber strength and good processability, and has a great significance for the processes of the rubber such as mixing, transportation, storage and the like. The problem of incompatibility of polar silica and rubber is solved to a certain degree, and a theoretical basis is provided for overcoming the contradiction between the reduction of rolling resistance of tyres and the improvement on wet skid resistance.