34results about How to "Inhibit scar hyperplasia" patented technology

An artificial vessel of polysaccharide is composed of a layer of polysaccharide fiber and a film layer which is formed by coating polysaccharide solution on the layer of polysaccharide fiber. The polysaccharide is one or two compounds selected from the group consisting of carboxymethyl cellulose, hydroxypropyl cellulose, hydroxyethyl cellulose, hyaluronic acid, alginate, heparin, chondroitin sulfate, chitin, hydroxymethyl chitin, hydroxypropyl chitin, hydroxyethyl chitin, carboxymethyl hydroxypropyl chitin, carboxymethyl hydroxyethyl chitin, hydroxypropyl hydroethyl chitin, sulfonated chitin, chitosan, carboxymethyl chitosan, hydroxypropyl chitosan, hydroxyethyl chitosan, carboxymethyl hydroxyethyl chitosan, carboxymethyl hydroxypropyl chitosan, hydroxypropyl hydroethyl chitosan, sulfonated chitosan or succinyl chitosan. The artificial vessel of polysaccharide has good tightness, tensility, pliability, mechanical strength and flexibility.

The invention provides a preparation method and application of a traditional Chinese medicine hydrogel. The hydrogel is prepared from Phellodendron Phellodendri extract and a hydrophilic matrix. After external use, the hydrogel can inhibit scar hyperplasia, promote scar softening, and prevent postoperative scars The production of tissue, and the preparation method is simple and the side effects are small, so it can be widely used in the prevention of postoperative scars in surgical patients.

The invention relates to a collagen-based composite scaffold material and its preparation method and application. The material includes collagen and water-soluble polysaccharide. The water-soluble polysaccharide is at least one of chitosan, seaweed polysaccharide salts, proteoglycan, cellulose, carrageenan, gum arabic and starch. The collagen has a three-dimensional network structure of natural fibers. The preparation method of the bracket material is as follows: choose mammalian skin as raw material, remove the subcutaneous tissue with a splitter, then soak in water, degrease, lime, delime, split, soften, compound, and sterilize by cobalt 60 irradiation. Adding functional materials to the collagen-based composite support material can be used to prepare biological dressings, artificial epidermis, artificial dermis, and artificial composite skin, and the collagen-based composite support material can also be used in conjunction with ointments. The bracket material has good permeability, water vapor permeability and absorption.

The invention provides a pharmaceutical composition for treating burns and scalds as well as a preparation method and application thereof. The pharmaceutical composition is prepared from an effectivecomponent a and an effective component b, <0}{0><}0{>wherein the component a has the effects of clearing away heat and toxic materials as well as diminishing inflammation and relieving pain and is prepared from the following raw materials: 10-40 parts of giant knotweed rhizome, 5-35 parts of dandelion herb, 5-35 parts of lithospermum herb and 1-20 parts of borneol; <0}{0><}0{>and the component b has the effects of promoting blood circulation and removing blood stasis as well as removing necrotic tissue and promoting tissue regeneration and is prepared from the following raw materials: 10-40 parts of radix et rhizoma rhei, 10-40 parts of garden burnet root, 1-20 parts of radix codonopsis, 1-20 parts of radix astragali and 50-200 parts of egg white. <0}{0><}0{>The pharmaceutical compositionhas the advantages that medicines are respectively applied according to different effects of the traditional Chinese medicines, so that synergetic effects of the Chinese traditional medicine components can be fully exerted; compared with single drug prescription administration, the pharmaceutical composition has more obvious and stable curative effects; <0}{0><}0{>the pharmaceutical composition ismainly used for treating diseases caused by red, swollen, hot and painful wounds in preliminary and intermediate stages of burns and scalds and obvious exudation, reducing wound infection, accelerating wound healing and effectively reducing formation of ulcers at burn and scald parts, and is low in cost and free of toxic or side effect; <0}{0><}0{>and the preparation method of the pharmaceuticalcomposition is simple and feasible, all parameters are controllable, and large-scale production is facilitated.

The present invention provides a composition for preventing scar hyperplasia, comprising a scar-removing component, an emollient component I and an emollient component II, and the scar-removing component includes the following ingredients in parts by weight: shea butter 0.4 ~0.6 parts, avocado oil 0.4~0.6 parts, allantoin 0.1~0.3 parts and ginseng root extract 0.15~0.25 parts. The present invention also provides the repairing cream made from the scar removing component and the moisturizing component I, the repairing gel made from the moisturizing component II, and the repairing suit composed of the repairing cream and the repairing gel. The repair kit for preventing scar hyperplasia provided by the present invention can effectively inhibit scar hyperplasia and promote wound healing; shea butter, avocado oil, allantoin and ginseng extract in the repair cream have the functions of promoting wound healing and inhibiting scar hyperplasia function; the rest of the ingredients have the effect of moisturizing and emollient; the repair gel can promote cell renewal, maintain cell activity, and further improve the effectiveness of scar suppression.

The invention relates to the field of a traditional Chinese medicine, and particularly relates to a drug for repairing a skin injury and a preparation method of the drug. The drug comprises a topical agent prepared from the following components in parts by weight: 20-25 parts of egg yolk oil, 15-25 parts of tetrastigma hemsleyanum, 15-20 parts of angelica oil, 10-15 parts of lavender essential oil and 25-40 parts of sesame oil. The drug for repairing the skin injury has good treatment effects on various degrees of skin injuries, and especially has a unique curative effect on deep second skin trauma. The curative effect is mainly reflected as follows: the skin injury can be cured by direct external application, does not need skin grafting, and is short in treatment cycle. The clinical test proves that the deep second skin trauma can be cured after 2-3 weeks when being treated by using the drug for repairing the skin injury. Compared with the traditional skin grafting, the treatment course is shortened by at least 10-30 days, and the drug can be used for stopping pain, resisting bacteria and diminishing inflammation, protecting the wound from being polluted, promoting wound healing, and carrying out reducing repairing on the skin, and is safe and free of a side effect.

The invention provides an anti-scar biomaterial, a preparation method and use thereof, and relates to the technical field of biomedical materials. The material includes polysaccharide hydrogel and small molecule compound CSF1-R inhibitor. The anti-scar biomaterial of the invention can effectively inhibit the formation of hypertrophic scar and improve the curative effect of clinical tissue healing.

The invention discloses a clean fine-core sterile heterogeneous sigmoid membrane as well as a preparation method and clinical application thereof. A clean fine-core sterile heterogeneous sigmoid membrane biological novel material is successfully manufactured. A pig sigmoid membrane is taken as an animal model and subjected to experimental investigation of substrate application. The heterogeneous sigmoid membrane prepared by the preparation method disclosed by the invention can block body stress response of a patient with extensive burns, can lower super-high metabolism and can keep the remaining skin structure necessary for later-period skin regeneration. After the wound surface is cleaned and sterilized in a treatment process, the dressings can be not changed, skin can be not grafted, operation can be not carried out, the wound surface is protected from pollution and complication is avoided, so that cure rate for extensive burns is improved; moreover, scar hyperplasia is restrained, and disability rate of the patient is reduced.

Provided is a hydrogel scar removing patch and a preparation method. The hydrogel scar removing patch comprises a compound aloe hydraulic fixing layer, a silicone gel film and a polypropylene film stripping layer, the aloe hydraulic fixing layer is connected with the silicone gel film, and the upper portion of the silicone gel film is provided with the polypropylene film stripping layer. The hydrogel scar removing patch is used for treating bruises, scalds, scratches, cuts and the like.

The invention discloses an oligomeric chitosan medical wound care film and a preparation method thereof. The medical wound care film uses water-soluble oligomeric chitosan as a base material and can be made into solutions, sprays, etc., and has the functions of hemostasis, reducing The function of interstitial fluid exudation and prevention of tissue adhesion makes the product have good biocompatibility, hemostasis, antibacterial and moisturizing properties, and at the same time, it can also effectively prevent the liquefaction of wound fat. It can be used for wound treatment to prevent wound infection and promote rapid wound healing. , especially for the care of chronic hard-to-heal or burn wounds.

The invention relates to a medical composite nanofiber dressing and a preparation method thereof. The dressing is divided into inner and outer layers, wherein the inner layer contains polyvinyl alcohol, collagen and quaternized chitosan, and the outer layer contains polycaprolactone and dodecyl substituted quaternized silicone, polyvinyl alcohol, After mixing collagen and quaternized chitosan, the inner layer PCQC5 was prepared by electrospinning; polycaprolactone and dodecyl-substituted quaternized silicone QP12 were used as raw materials, and on the basis of the inner layer PCQC5, The outer layer was prepared by electrospinning. The dressing can be used in tissue repair or scar repair, and has wide applications in the field of antibacterial materials or medical devices.

The invention provides a traditional Chinese medicine composition comprising extracts of Coptidis Rhizoma, Myrrha, Dandelion, Viola didin and peppermint oil. The present invention comprehensively utilizes the pharmacological effects of each medicinal material, and combines them to exert a synergistic effect, significantly improving the therapeutic effect of a single herb or several of them, and can be combined with a moisturizing and non-irritating matrix to make a compound Chinese medicine Ointment, which can specifically treat and alleviate skin diseases caused by tumor-targeting drugs.

The invention relates to a Chinese medicinal composition for treating burns and scalds. The Chinese medicinal composition is composed of, by mass: 3-5 parts of propolis, 0.5-1 part of borneol, 5-15 parts of phellodendron, 10-20 parts of beeswax, 5-10 parts of Sanguisorba officinalis, 5-10 parts of radix rehmanniae, 5-10 parts of Rhizoma Coptidis, 5-10 parts of rhubarb, 5-10 parts of Scutellaria baicalensis, 1-3 parts of lithospermum, and 450-550 parts of sesame oil. The preparation method of the Chinese medicinal composition includes: grinding borneol, radix rehmanniae, Rhizoma Coptidis, and lithospermum into a fine powder respectively, and sieving the powder by a sieve of 80-120 meshes for standby use; putting sesame oil and beeswax into a pot, conducting heating and stirring simultaneously, and after melting of the beeswax, performing cooling to 70-80DEG C, adding borneol, further conducting cooling to 40-50DEG C, adding the residual components, stirring the mixture uniformly, thus obtaining a thick paste or paste. The Chinese medicinal composition provided by the invention solves the problems of long treatment cycle and slow effect in existing ointments for treating burns and scalds, has the effects of clearing away heat and toxic materials, removing necrotic tissues and promoting granulation, relieving pain, promoting blood circulation and removing blood stasis, and can effectively prevent infection and inhibit scar hyperplasia.

The invention relates to a medical colloid dressing and application thereof, in particular to a medical colloid dressing with the effects of easing pain, promoting surface of burns and scalds healing and restraining bacteria and application thereof. The dressing mainly comprises water-soluble chitin and chlorhexidine.

The invention discloses a skin wound repair ointment and a preparation method thereof. The skin wound repair ointment is prepared from chitosan, a bioactive peptide, calamine, glycerin, agar and water. The preparation method comprises the following steps: (1) dissolving chitosan into water to prepare a chitosan solution, adding the bioactive peptide and glycerin so as to obtain a chitosan mixed solution; (2) dispersing the agar into water, and heating until the agar is dissolved so as to prepare an agar solution; (3) mixing the agar solution and the chitosan mixed solution, adding powdered calamine, uniformly mixing, and standing. According to the method disclosed by the invention, the natural antibiotic chitosan serves as a main matrix and is compounded with the bioactive peptide with effects of promoting wound healing and inhibiting scar hypertrophy, the binding state is regulated by adopting the calamine, the prepared skin wound repair ointment achieves the effects of resisting bacteria and diminishing inflammation, removing slough and promoting growth of tissue regeneration, clearing away heat and toxic materials, converging healing, inhibiting scar hypertrophy and the like and is particularly applicable to treatment of scalds and burns of deep II degree or higher, and no obvious scar residue exist.

The invention discloses Chinese medicinal ointment for treating burn. The Chinese medicinal ointment consists of the following ingredients: sesame oil, rhubarb, garden burnet root, borneol, bupleurum, swordlike atractylodes rhizome, angelica dahurica, honeysuckle flower and golden thread. The Chinese medicinal ointment has the advantages that: ingredients are simple, the effective rate is high, pain is relieved quickly, an effect is obvious, the Chinese medicinal ointment is suitable for patients who suffer from burn of various areas and depths, is used for relieving pain, inhibiting infection and helping injured cells and injured tissue to be propagated and differentiated, and has an obvious effect of promoting to repair wounds quickly, and a preparation method is easy; pain caused by diathermy and skin grafting in the conventional method are avoided; and the treated wounds are smooth and high in healing quality, chromatosis is reduced, and the formation of skin scars is prevented effectively.