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Preparation method and application of traditional Chinese medicinal hydrogel

A technology of hydrogel and traditional Chinese medicine, which is applied in the field of medicine, can solve the problems of inconsistent effects, cumbersome production process, and high price, and achieve the effects of low component toxicity, convenient material acquisition, and inhibition of pigmentation

Inactive Publication Date: 2015-04-08
XI AN JIAOTONG UNIV
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Problems solved by technology

[0006] Postoperative scar formation can be suppressed by means of surgery and radiotherapy. There are also some drugs used to prevent postoperative scars in the market, but they are more expensive, the production process is cumbersome, and the effect is different. Therefore, it is urgent to explore a new drug that is easy to prepare. , Drugs used to prevent postoperative scarring

Method used

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Embodiment Construction

[0022] The present invention is described in detail below in conjunction with embodiment.

[0023] Through previous clinical observations, it was found that Phellodendron Phellodendri Extract (Phelloderma Phellodendron Liquid) can effectively prevent postoperative scar formation. Based on the previous research on Phellodendron Phellodendri and hydrogel, it is considered to use hydrogel in the prevention and treatment of postoperative scar. Specifically, as follows:

[0024] (1) the present invention provides a kind of preparation method of the Chinese medicine hydrogel that is used to prevent postoperative cicatrix, comprises the following steps:

[0025] 1) Add 15g Phellodendron Phellodendron to 200mL water, heat to boil, after boiling, continue to decoct on low heat for 2.0 hours, then naturally cool to room temperature, after cooling, use sterile gauze and funnel to filter to obtain 50g of Liquid A (that is, Phellodendron Phellodendron Liquid);

[0026] 2) Weigh 80g of pol...

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Abstract

The invention provides a preparation method and application of traditional Chinese medicinal hydrogel. The traditional Chinese medicinal hydrogel is prepared from cortex phellodendri extracting solution and hydrophilic matrix and has the effects of inhibiting hypertrophic scar, accelerating scar softening and preventing formation of scar tissue after operation; meanwhile, a preparation method is simple, and side effect is small, so that the traditional Chinese medicinal hydrogel can be widely applied in prevention of formation of scar tissue after operation.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine hydrogel for preventing postoperative scar formation. Background technique [0002] Scarring is an inevitable result of wound repair. Keloids or scar hyperplasia that accompany wound healing not only affect the appearance but also lead to varying degrees of tissue and organ dysfunction. Because it is difficult to control, there is no very satisfactory treatment plan in China so far. The fundamental principle of scar treatment is to remove the lesion and prevent its recurrence by inhibiting the proliferation of fibroblasts and their collagen synthesis, secretion or deposition. Currently, effective treatment options mainly include surgery, drug therapy, radiation therapy, laser, and cryotherapy. Drug therapy plays an important role in the treatment of scar. [0003] Phellodendron amurense is the dry bark of Phellodendron amurense (Phe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/06A61P17/02
CPCA61K9/0014A61K9/06A61K36/756A61K47/10A61K2236/331A61K2236/53
Inventor 代志军林帅李莎王西京康华峰李小宁
Owner XI AN JIAOTONG UNIV
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