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A kind of traditional Chinese medicine composition and application

A composition and technology of traditional Chinese medicine, applied in traditional Chinese medicine composition and application field, to achieve important clinical application and development value, inhibit scar hyperplasia, and improve the effect of treatment effect

Active Publication Date: 2022-03-29
南京新康力医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are currently no traditional Chinese medicines, traditional Chinese medicine compound prescriptions or Chinese patent medicine preparations specifically for adverse skin reactions caused by targeted tumor therapy drugs, some traditional Chinese medicine preparations for common skin diseases have gradually entered the clinical treatment of skin diseases, and according to the formation mechanism of skin diseases and clinical symptoms, developed new Chinese medicine treatment prescriptions and modern preparations (CN1268367C, CN103520390B, CN1157203C, CN107213397A, etc.)

Method used

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  • A kind of traditional Chinese medicine composition and application
  • A kind of traditional Chinese medicine composition and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The Coptidis Rhizoma extract described in the present invention is obtained by spray-drying the water extract of Coptidis Rhizoma 10:1; the myrrh extract is obtained by spray-drying the water extract of Myrrha 10:1; The 10:1 water extract was obtained by spray drying; the viola extract was obtained by spray drying the 10:1 water extract of Viola.

[0034] Prescription 1:

[0035] Sodium carboxymethyl cellulose 20g Coptidis Extract 0.5g myrrh extract 1g Dandelion Extract 1g Viola extract 1g peppermint 0.1g glycerin 100g

[0036] (1) The sodium carboxymethyl cellulose that takes prescription quantity is dissolved in 400mL pure water and swells overnight;

[0037] (2) Measure 250mL of pure water and heat to dissolve the extract freeze-dried powder of Coptis Rhizoma, Myrrha, Dandelion, and Viola Dipin;

[0038] (3) the sodium carboxymethylcellulose obtained in step (1) is mixed with the aqueous drug solution obtained in st...

Embodiment 2

[0042] Prescription 2:

[0043] Sodium carboxymethyl cellulose 20g Coptidis Extract 2.5g myrrh extract 5g Dandelion Extract 4g Viola extract 8g peppermint 0.1g glycerin 100g

[0044] Weigh each Chinese medicine extract and matrix material of prescription 2, and prepare the preparation of the present invention according to the preparation process of Example 1.

Embodiment 3

[0046] Prescription 3:

[0047] Sodium carboxymethyl cellulose 20g Coptidis Extract 1g myrrh extract 2.5g Dandelion Extract 2g Viola extract 4g peppermint 0.1g glycerin 100g

[0048] Weigh each Chinese medicine extract and matrix material of prescription 3, and prepare the preparation of the present invention according to the preparation method of Example 1.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition comprising extracts of Coptidis Rhizoma, Myrrha, Dandelion, Viola didin and peppermint oil. The present invention comprehensively utilizes the pharmacological effects of each medicinal material, and combines them to exert a synergistic effect, significantly improving the therapeutic effect of a single herb or several of them, and can be combined with a moisturizing and non-irritating matrix to make a compound Chinese medicine Ointment, which can specifically treat and alleviate skin diseases caused by tumor-targeting drugs.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, in particular to a traditional Chinese medicine composition and its application. Background technique [0002] With the continuous emergence of anti-tumor molecular targeted therapy drugs and the expansion of indications, more and more cancer patients will choose such drugs to reduce the adverse reactions of chemotherapy and improve the quality of life. However, targeted antineoplastic drugs often cause more skin adverse reactions, among which symptoms such as papules, pustules, macules, urticaria, itching, dry and chapped skin, edema, skin ulcers, and delayed skin wound healing are common (Zhang Meihua. China Medical Abstracts, 2016,33(6):710-722.). [0003] Although there are many types of drugs for the treatment of rashes at present, all of which can achieve the purpose of preventing or relieving symptoms, they mainly focus on anti-allergic drugs, hormones and antibiotics, such as a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/86A61K9/06A61P17/00A61P17/02A61P17/04A61P7/10
CPCA61K36/718A61K36/328A61K36/288A61K36/86A61K36/534A61K9/06A61K9/0014A61K47/38A61P17/00A61P17/02A61P17/04A61P7/10A61K2300/00
Inventor 卢张伟李海云
Owner 南京新康力医药科技有限公司
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