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366results about How to "Improve energy transfer" patented technology

Guided cardiac ablation catheters

Guided ablation instruments are disclosed for creating lesions in tissue, especially cardiac tissue for treatment of arrhythmias, including atrial fibrillation. In one aspect of the invention, a percutaneous catheter is disclosed with an endoscope positionable in the instrument's distal end region to obtain an image. The image allows the clinician to determine whether contact has been achieved (or blood has been cleared from an ablative energy transmission path) before ablation begins or while ablation is occurring. In one embodiment, percutaneous ablation catheters are disclosed having at least one central lumen and one or more balloon structures at the distal end region of the instrument. Also disposed in the distal end region are an illuminating light source and an endoscope capable of collecting sufficient light to relay an image to the user. The instruments can further include an ablation element. The ablation element can be a contact ablation element, or a radiant energy emitter, which is preferably independently positionable within the lumen of the instrument and adapted to project ablative energy through a transmissive region of the instrument body (and/or balloon) to a target tissue site proximate to the pulmonary veins. The energy can delivered without the need for contact between the energy emitter and the target tissue so long as a clear transmission pathway is established. The endoscope element of the instrument allows the clinician to determine the position of the instrument and, if radiant energy is to be employed, see if such a pathway is clear. Moreover, because the position of the radiant energy emitter can be varied, endoscopic guidance permits the clinician to select a desired location and dose for the lesion.
Owner:CARDIOFOCUS INC

Flow measuring apparatus

A flow measuring apparatus (300, 500) measures a fluid flow (130) within a conduit (120) including a wall (110). The apparatus (300, 500) includes a transducer arrangement including at least two transducers (100A, 100B) for alternately emitting and receiving ultrasonic radiation through the conduit wall (110) and the flow (130). The apparatus (300, 500) also includes a signal processing arrangement (310) for generating signals to excite the transducer arrangement (100A, 100B) and for processing received signals provided by the transducer arrangement (100A, 100B) for generating output signals from the signal processing arrangement (310) indicative of properties of the flow. The transducer arrangement (100A, 100B) in cooperation with the conduit (120) provides a first path (200) for Lamb-wave ultrasonic radiation coupling directly from a first of the at least two transducers (100A, 100B), to a second of said at least two transducers to generate a first received signal. The transducer arrangement (100A, 100B) in cooperation with the conduit (120) provides at least one second path (210) for ultrasonic propagation along the wall (100) via Lamb waves coupling to at least a portion of the flow (130) from a first of the at least two transducers (100A, 100B) to a second of the at least two transducers (100A, 100B) to generate a second received signal. The signal processing arrangement (310) determines from said first and second received signals ultrasonic radiation propagation time periods through the first path (200) and through the at least one second path (210), and to perform computational operations on the propagation time periods to determine properties of the flow including, but not limited to, at least one of: fluid flow velocity (v) in the conduit (120), a sound velocity (c) through the fluid (130).
Owner:XSENS

Compounds for fluorescence imaging

Methods and compositions involving enzyme-activatable fluorophore polymer imaging agents for photodetection of specific tissues and / or human diseases and disorders are provided. In certain embodiments, the imaging agent comprises a hydrophilic polymer backbone (e.g., poly(L)lysine), a hydrophobic fluorophore, and a hydrophilic solubilizing agent. The solubilizing agent may comprise a quarternary ammonium group (e.g., a 1-methylnicotinic group) to enhance self-quenching of the fluorophore. Various methods for the generation and purification of imaging agents are also provided, including methods involving solid phase probe extraction or ion exchange purification.
Owner:UNIVERSITY OF GENEVA

Bulletproof composite board

The invention discloses a bulletproof composite board comprising an buffer layer as the external layer, an absorption layer connected with the buffer layer, and a barrier layer connected with the absorption layer, wherein the buffer layer comprises a plurality of disks superposed into a scalelike structure, and the disks are provided with a convex surface towards the external layer; the absorption layer comprises weftless fabric pressure layers and knitted fabrics, which are superposed, and the weftless fabric pressure layers and the knitted fabrics comprise fibers of which the strength is atleast 15 cN / dtex and the modulus is at least 390 cN / dtex; and the barrier layer comprises a metal plate of which the tensile strength is greater than 1000 MPa. A bullet is deflected under the action of the convex surface of the disks, and the penetrating capability of the bullet is reduced; under the alternate actions of the weftless fabrics and the knitted fabrics, the energy of the bullet is quickly transferred and absorbed; and finally, the bullet is effectively prevented when getting into contact with the barrier layer with high strength.
Owner:杨珍芬
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