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Energy delivery systems and uses thereof

A technology of energy transmission and energy transmission, applied in the field of comprehensive systems, can solve the problems around the insertion area of ​​burn equipment, the limitation of microwave equipment, and not easy to insert, etc.

Active Publication Date: 2009-08-19
NEUWAVE MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, larger diameter feeders are undesirable because they are less easily inserted percutaneously and increase the rate of procedural complications
Microwave devices are also limited to a single antenna for most applications, limiting the ability to treat multiple areas simultaneously, or to place several antennas in close proximity to form large tissue heating zones
In addition, the heating of the feedline at high power can cause burns around the area where the equipment is inserted

Method used

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  • Energy delivery systems and uses thereof
  • Energy delivery systems and uses thereof
  • Energy delivery systems and uses thereof

Examples

Experimental program
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Effect test

example 1

[0167]This example demonstrates the avoidance of undesired tissue heating by circulating a coolant through cooling channels using the energy delivery device of the present invention. The ablation needle shaft used for all experiments was 20.5 cm. Cooling of the handle assembly is minimal, indicating that handle cooling is well isolated. Temperature probes 1, 2 and 3 are located 4, 8 and 12 cm adjacent to the tip of the stainless steel needle (see Figure 9 ). Temperature measurements were taken for the 35% power measurement after insertion of the pig liver, and for the 45% power measurement after insertion of the pig liver. For 35% power measurements, probe 4 is on the handle itself. For the 45% power measurement, probe 4 was located at the needle-skin interface approximately 16 cm from the stainless steel needle tip.

[0168] Such as Figure 10 As shown in , 10 minutes of treatment at 35% power with a featureless high (6.5%) reflected power showed that at probes 1, 2, 3 ...

example 2

[0171] This example demonstrates generator calibration. Generator calibration is done at the factory with Cober-Muegge and set to be very accurate for powers greater than 150W. A magnetron acts very much like a diode: increasing the cathode voltage does not increase the vacuum current (proportional to output power) until a critical threshold is reached, where the vacuum current increases rapidly with voltage. Control of a magnetron source relies on accurate control of the cathode voltage near a critical point. Thus, the generator is not specified for 0-10% power, and below 15% the correlation between output power and theoretical power percentage input is poor.

[0172] To test the generator calibration, vary the power control dial from 0.25% in 1% increments (corresponding to a theoretical output power of 0-75W in 3W increments), record the output power display of the generator, and measure the power output . Adjust the measured power output to account for the measured loss...

example 3

[0175] This example illustrates the setup and testing of an antenna during manufacturing. This provides a method of setup and testing in a manufacturing environment. The method uses a liquid, tissue-equivalent phantom, rather than tissue.

[0176] Based on numerical and experimental measurements with closed antennas, it is known that a change in L2 of ~1mm will increase the reflected power from <-30dB to ~-20-25dB. Changes in tissue properties that occur during ablation may make this increase less pronounced, so we would consider a relative tolerance of 0.5 mm for length L2 to be reasonable. Likewise, a tolerance of 0.5 mm with respect to length L1 is used even though the overall reflection coefficient is less dependent on L1 than L2.

[0177] Testing of antenna tuning for quality control can be achieved using liquid solutions for simulating the dielectric properties of liver, lung or kidney (see, e.g., Guy AW (1971) IEEE Trans. Microw. Theory Tech. 19: 189-217 ; hereby inc...

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Abstract

The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for treating a tissue region (e.g., a tumor) through application of energy.

Description

technical field [0001] The present invention relates to an integrated system for delivering energy to tissue for a variety of applications, including medical procedures (e.g., tissue ablation, resection, cauterization, vascular thrombosis, treatment of cardiac arrhythmias and irregular rhythms, electrosurgery, tissue harvesting, etc.) , apparatus and method. In some embodiments, systems, devices, and methods are provided for treating tissue regions (eg, tumors) through the application of energy. Background technique [0002] Ablation is an important therapeutic strategy for the treatment of certain tissues, such as benign and malignant tumors, cardiac arrhythmias, cardiac arrhythmias, and tachycardia. Many approved ablation systems use radio frequency (RF) energy as the source of ablation energy. Thus, a wide variety of RF-based catheters and power sources are currently available to physicians. However, RF energy has several limitations, including rapid dissipation of ene...

Claims

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Application Information

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IPC IPC(8): A61B18/18
CPCA61B2018/00011A61B2018/00017A61B18/1477A61B18/1815A61B2018/00023A61B2018/00744A61B2018/00642A61B2018/00005A61B2018/00791A61B18/18A61B2034/101A61B2034/104
Inventor D·W·万德韦德F·T·李P·F·雷斯克C·L·布雷斯
Owner NEUWAVE MEDICAL
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