47results about How to "Improve blood lipid levels" patented technology

The invention belongs to the field of pharmacology of Chinese medicines and discloses an application of a Chinese herb Pien Tze Huang and a preparation thereof in preparation of drugs for treating non-alcoholic fatty liver disease (NAFLD). The Chinese herb Pien Tze Huang can be used for remarkably improving the liver function of a fatty liver rat, reducing the AST (Aspartate Aminotransferase), TG (Triglyceride) and (gamma-Glutamyl Transpeptidase) level of serum, reducing the degree of fatty liver and relieving inflammatory reaction and has a remarkable curative effect on the aspect of treating NAFLD.

The invention discloses traditional Chinese medicine composition for treating metabolic syndrome. The traditional Chinese medicine composition consists of the following components: radix Angelica sinensis, radix notoginseng, radix ginseng, rhizoma alismatis, folium nelumbinis, fructus mume, fiveleaf gynostemma herb, semen cassiae, bulbus allii macrostemi, cassia twig, fructus aurantii immaturus, radix saliviae miltiorrizae, rhizoma coptidis, fructus crataegi, cactus, semen raphani, semen litchi, radix astragali, aloes, poria cocos, radix stephaniae tetrandrae, cortex cinnamomi, squama manis, radix curcumae, herba leonuri, fructus amomi, radix puerariae, folium lycii, radix bupleuri, radix rehmaniae recens, fructus corni, rhizoma dioscoreae, radix trichosanthis, herba epimedii, semen strychni, semen plantaginis and the like. According to the traditional Chinese medicine composition, the components are combined and complement each other; the traditional Chinese medicine composition can be effectively used for dialectically treating the metabolic syndrome, improving blood lipid level, relieving insulin resistance and obese state, and the like; and the traditional Chinese medicine composition is convenient to prepare, small in side effect, high in safety and low in price, and provides a technical basis for research and development of metabolic syndrome and complication treatment drugs.

The invention discloses a high-energy-density casein type full-nutrition special medical food emulsion and a preparation method thereof, and relates to the technical field of medical foods. The emulsion comprises proteins, carbohydrates, fat, vitamins, minerals, dietary fibers, taurine, L-carnitine, nucleotides, emulsifying thickeners, taste regulators and water; every 100mL of the emulsion is prepared from 0.1g to 15g of proteins, 0.1g to 50.0g of carbohydrates, 0.1g to 10.0g of minerals, 0.01g to 2.0g of vitamins, 0.01g to 5.0g of an emulsifier agents, 0.01g to 3 g of thickeners, 0.001g to 0.1g of taurine, 0.001g to 0.1g of nucleotides, 0.001g to 0.1g of L-carnitine and 0.09g to 0.54g of taste regulators. The formula disclosed by the invention is scientific and reasonable in energy proportion and rich in protein content, the calcium caseinate can provide amino acid necessary for normal vital activities of a body, and immune components including bovine colostrum, soybean oligopeptideand marine fish oligopeptide are added to improve the immunity of the body.

The invention discloses an application of a peanut coat active component and a composition comprising the peanut coat active component. The peanut coat active component can be used for preparing foods and medicines for preventing and treating neurodegenerative diseases. The invention also provides a composition comprising the peanut coat active component and Omega-3 series unsaturated fatty acid. The invention provides a new application of the peanut coat active component, thus offering a new thinking for preparing foods and medicines for preventing and treating neurodegenerative diseases like Alzheimer's disease. In addition, the composition also contains omega-3 series unsaturated fatty acid besides the peanut coat active component, thus better improving memory function.

The invention discloses a traditional Chinese medicinal composition for treating metabolic syndrome. The traditional Chinese medicinal composition consists of the following components: radix angelicae sinensis, radix notoginseng, ginseng, rhizoma alismatis, lotus leaves, dark plums, fiveleaf gynostemma herb, semen cassiae, platycodon root, liquorice root, fructus xanthii, bulbus allii macrostemi, cassia twig, radix paeoniae alba, radix salviae miltiorrhizae, rhizoma coptidis, fructus crataegi, herba houttuyniae, peach kernels, semen raphani, semen litchi, radix astragali, common dayflower herb, honeysuckle flowers, dandelion, mung beans, aloe, poria cocos, radix stephaniae tetrandrae, herba dianthi, lagenaria siceraria, radix curcumae, herba leonuri, fructus amomi, radix puerariae and folium lycii. The traditional Chinese medicinal composition disclosed by the invention, through the compatibility of the various medicines which complement each other, is effectively applicable to the dialectical treatment of the metabolic syndrome, and the traditional Chinese medicinal composition is capable of improving blood lipid level, relieving insulin resistance and obesity state, and the like. The traditional Chinese medicinal composition disclosed by the invention is convenient to prepare, low in side effect, high in safety and low in cost; and the traditional Chinese medicinal composition provides a technical basis for the research and development of medicines for treating integral metabolic syndrome and complications thereof.

The invention provides a compound slow-release tablet of simvastatin and nicotinic acid and a preparation method thereof. The method prepares the slow-release nicotinic acid and the simvastatin into a compound tablet for the first time. In the compound tablet, each tablet contains 250-2000mg of nicotinic acid and 5-50mg of simvastatin. The compound tablet is prepared by the following steps: preparing a simvastatin quick-release tablet and preparing the compound slow-release tablet of the simvastatin and the nicotinic acid. The compound nicotinic acid slow-release tablet prepared by the method is suitable for the treatment of primary hypercholesteremia and mixed type blood lipid abnormality, takes the nicotinic acid as a slow-release part and the simvastatin as a quick-release part according to the respective properties, prepares a compound preparation, enables each component to exert a synergistic action in vivo, exerts the medicine effect furthest, can lower the side effect of the medicine, reduces the fluctuation of the blood concentration in vivo, reduces the administration frequency of a patient and has more obvious curative effect for relieving the hypercholesteremia in comparison with that of a method which only takes any one single-prescription preparation.

The invention provides an edible composition having the efficacy of assisting in improving blood fat level and an application of the edible composition, in particular an edible composition containinglinseed oil. The edible composition consists of the following raw materials of linseed oil, isomerized lactose and soybean peptide powder, wherein the mass ratio of the linseed oil to the isomerized lactose to the soybean peptide powder is 1 to (0.16-1.0) to (0.03-0.05). The composition can be added to liquid dairy products, and the liquid dairy products having favorable stability and favorable mouth feel within long shelf life can be made; and the composition and the liquid dairy products can improve the blood fat level to a certain extent after being eaten, can assist in reducing blood fat and is beneficial for human health.

The invention provides a humanized pika leptin protein, a gene coding the protein. The nucleotide sequence and the amino acid sequence are respectively shown as SEQ ID No. 1 and SEQ ID No. 2. The invention further provides an expression and purification method of the humanized pika leptin recombinant protein which is soluble. The invention builds an animal model of hyperglycemia and hyperlipidemia, and uses the humanized pika leptin recombinant protein and a human leptin protein to cure, and results show that the humanized pika leptin protein, similar with the human leptin protein, can obviously reduce blood glucose concentration and total cholesterol, triglyceride levels of serum, reduce content of visceral white adipose tissue and accumulation of intracellular fat, and promote expression level of key genes participating glycometabolism and lipid metabolism in liver. Compared with human recombinant leptin protein, the humanized pika leptin protein has a relatively obvious effect for improving blood glucose and reducing blood lipid.

The invention provides an extract of rust-coloured crotalaria herb with root for treating cardiovascular disease, and a preparation method and application thereof. The extract of rust-coloured crotalaria herb with root comprises sterides and oleanolic acid which can effectively improve lipid levels of mice suffering from hyperlipemia, reduce serum total cholesterol, and low density lipoprotein cholesterin, and prevent and treat cardiovascular disease; and the preparation method for the extract is simple, slightly pollutes environment and is suitable for large-scale industrial production.

The invention relates to a traditional Chinese medicine composition for treating obesity and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 8-16 parts of radix scutellariae, 25-35 parts of radix puerariae, 10-20 parts of radix arnebiae seu lithospermi and 6-12 parts of rhizoma atractylodis. The traditional Chinese medicine composition is reasonable in compatibility, safe, effective and capable of removing middle-jiao damp-heat and enhancing transportation and transformation of the spleen and the stomach. The traditional Chinese medicine composition can effectively reduce the weight of a high-fat feed induced simple obese rat, improve the blood fat level of the obese rat and reduce the content of inflammatory factors. The traditional Chinese medicine composition can reduce the body mass and body fat amount of obese patients and improve body fat distribution, is safe and reliable, has no adverse reaction in use, and is suitable for clinical popularization and use.

Provided is a method for preparing a genetically-engineered hamster comprising in vivo knocking out an LDL receptor gene in the hamster. The LDL receptor gene is knocked out by CRISPR/CAS9 gene editing technique. The genetically-engineered hamster shows significantly high levels of blood lipids, and it thus well-suited for direct use in hyperlipidemia and arteriosclerosis studies, and is a small animal model with high similarities to human familial hypercholesterolemia. Also provided is a method for screening drugs using the genetically-engineered hamster.

The invention discloses a traditional Chinese medicine composition for treating level-1 and level-2 hypertension and a preparation method of the composition. The traditional Chinese medicine composition for treating level-1 and level-2 hypertension is characterized by comprising the following raw medical materials: ligusticum wallichii, rhizoma alismatis, semen raphani, seaweed and leech; and the traditional Chinese medicine composition is prepared through the steps of decocting, carrying out alcohol precipitation and the like for the raw medicinal liquid with the preparation amount. The traditional Chinese medicine composition has remarkable therapeutic effects on the level-1 and level-2 hypertension, not only reduces blood pressure, but also improves blood grease level of a patient and the hemorheology, increases a heart function, and is good for correcting disordered lipid metabolism of the patient. The preparation method is simple and good for production, and has no side effect.

The invention belongs to the technical field of health food, and particularly relates to a traditional Chinese medicine composition with an auxiliary blood fat reduction function and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises 20-50 parts of cyclocarya paliurus leaf, 25-55 parts of ampelopsis grossedentata leaf, 25-55parts of lophatherum gracile, 30-60 parts of green plum, 55-85 parts of hawthorn, 85-115 parts of pine pollen and 90-120 parts of radix puerariae. The traditional Chinese medicine composition can beadministrated independently as routine health food by a hyperlipidemia patient or matched with statin hypolipidemic drugs for use; the preparation method of the traditional Chinese medicine composition is stable, operable and suitable for industrial production; and the prepared composition is good in safety and has an obvious blood fat reduction effect.

The invention provides a feed for chinchilla. The feed is characterized by comprising the following raw materials in parts by weight: 20 to 30 parts of fresh alfalfa, 15 to 25 parts of corn silk, 15 to 30 parts of corn, 5 to 15 parts of flax seed, 1 to 5 parts of fish bone meal, and 2 to 8 parts of live earthworm. The feed is simple in components, the price is cheap, and the feed can provide required nutrients for chinchilla. Moreover, the provided preparation method can improve the palatability of the feed, at the same time effectively preserves the vitamins and plant active water in the raw material, and thus improves the self-immunity of the chinchilla.