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Application of Chinese herb Pien Tze Huang and preparation thereof in preparation of drugs for treating non-alcoholic fatty liver disease (NAFLD)

A non-alcoholic, Pien Tze Huang technology, applied in the new application field of Pien Tze Huang and its preparations in the preparation of drugs for treating non-alcoholic fatty liver, can solve the problems of large side effects, poor curative effect, complex etiology and pathogenesis of NAFLD, etc.

Inactive Publication Date: 2014-09-17
ZHANGZHOU PIEN TZE HUANG PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to the complex etiology and pathogenesis of NAFLD, there is still a lack of specific drugs. Commonly used statins, fibrates and other blood lipid-lowering drugs have poor efficacy and relatively large side effects

Method used

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  • Application of Chinese herb Pien Tze Huang and preparation thereof in preparation of drugs for treating non-alcoholic fatty liver disease (NAFLD)
  • Application of Chinese herb Pien Tze Huang and preparation thereof in preparation of drugs for treating non-alcoholic fatty liver disease (NAFLD)
  • Application of Chinese herb Pien Tze Huang and preparation thereof in preparation of drugs for treating non-alcoholic fatty liver disease (NAFLD)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0103] Take 85 parts by weight of panax notoginseng, 7 parts by weight of snake gall, 5 parts by weight of bezoar, and 3 parts by weight of musk, and make Pien Tze Huang lozenges according to traditional techniques, each 0.6-3.0g, for treating non-alcoholic fatty liver. 3 times a day, 0.3-0.9g each time.

Embodiment 2

[0105] Take the Pien Tze Huang lozenge in Example 1 and grind it into granules, add conventional excipients to make tablets according to the conventional process, each tablet contains 0.2-0.4 g of Pien Tze Huang, and is used for the treatment of non-alcoholic liver injury. 3 times a day, 2-4 tablets each time.

Embodiment 3

[0107] Get the Pien Tze Huang lozenge in Example 1 and pulverize into granules, fill capsules to make capsules, each capsule contains 0.2-0.4g, and is used for the treatment of non-alcoholic fatty liver. 3 times a day, 2-4 capsules each.

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Abstract

The invention belongs to the field of pharmacology of Chinese medicines and discloses an application of a Chinese herb Pien Tze Huang and a preparation thereof in preparation of drugs for treating non-alcoholic fatty liver disease (NAFLD). The Chinese herb Pien Tze Huang can be used for remarkably improving the liver function of a fatty liver rat, reducing the AST (Aspartate Aminotransferase), TG (Triglyceride) and (gamma-Glutamyl Transpeptidase) level of serum, reducing the degree of fatty liver and relieving inflammatory reaction and has a remarkable curative effect on the aspect of treating NAFLD.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacology, and in particular relates to a new application of Pien Tze Huang and its preparation in the preparation of medicines for treating non-alcoholic fatty liver. Background technique [0002] Non-alcoholic fatty liver disease (NAFLD) is a disease without a history of excessive drinking but associated with genetic, environmental, and metabolic stress. The pathological changes are characterized by steatosis and lipid accumulation in hepatic parenchymal cells . NAFLD includes nonalcoholic simple fatty liver, nonalcoholic steatohepatitis and its associated cirrhosis and hepatocellular carcinoma. With the development of my country's economy, the incidence of non-alcoholic fatty liver continues to increase and shows a trend of younger age, becoming a common disease that seriously threatens people's physical and mental health. [0003] Due to the complex etiology and pathogenesis of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61P1/16A61K35/58A61K35/55A61K35/413
Inventor 潘杰黄进明洪绯罗志毅陈志亮
Owner ZHANGZHOU PIEN TZE HUANG PHARM
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