The invention provides a traditional Chinese medicine composition for effectively treating xerophthalmia. The traditional Chinese medicine composition is prepared from cortex albiziae, butterflybush flower, fructus viticis, dandelion, herba eupatorii, spina date seed, folium eriobotryae, radix polygonati officinalis, seedling of capillary wormwood, fructus leonuri, folium mori, flos carthami, radix clematidis, calamine, dragon blood, aloe, flatstem milkvetch seed, silene conoidea, semen coicis, rubia tinctorum madder root, turnip root, seed of feather cockscomb, serrate rabdosia herb, inula flower, rhizoma corydalis decumbentis, curious kadsura root stem, manglietia fordiana fruit, all-grass of shiningfruit night-shade, ludisia discolor, oreas, herba ecliptae and herb of flabellate hemipilia. The traditional Chinese medicine composition is prepared through years of clinical tests and repeated verification, the medicinal materials are combined based on the development law of the disease and the compatibility principle of traditional Chinese medicines, synergism of the effects of different medicinal materials is achieved, and in this way, the traditional Chinese medicine composition has the advantages of being high in targeting property, good in treatment effect, high in effective rate, and free of toxic or side effect on human body. The traditional Chinese medicine composition is suitable for patients from young age to old age. The total effective rate is 93%, and the cure rate reaches 82%.