182results about How to "Improve anti-infection ability" patented technology

This invention relates to a micro-ecological agent and the preparation method thereof, belonging to the micro-ecological agent technological field. The preparation of the active bacteria agent of this invention comprises: using L-calcii lactas and four useful micro-organisms of clostridium bytyricum, Lactobacillus casei, bacillus subtilis and saccharomycete as characteristic elements, cultured purely or mixedly by means of universal fermentator, producing active bacteria powder by freeze-drying, and acquiring the finished products by double crossing of the powder at a specific proportion. By using the anaerobic and aerobic characteristics of related bacterial strains, this agent has the following merits: playing the synergy effect in enhancing the disease resistance of marine animals and the water purification of aquaculture, substituting antibiotics fully or partly for the disease prevention and cure in fresh water aquiculture and mariculture, and improving the economic benefits of aquaculture. The L-calcii lactase component can accelerate the husking growth and prevent the disease of soft husk of shellfish marine animals like shrimp and crab. This agent is characterized of being nontoxic, free from side effects, nonpersistent, without secondary pollution and no drug tolerance, and will have a wide commercial application in the fresh water aquiculture mariculture.

The invention relates to a high-energy composite peptide selenoprotein nutrient solution, a preparation method and an application thereof. The nutrient solution is composed of selenium raw material, protein, mineral substances, vitamin, natural energy minerals and the like; the high-energy composite peptide selenoprotein nutrient solution containing rich selenium element, the mineral substances, the vitamin and natural energy substances is prepared by performing enzymolysis on the protein, and conducting synthesizing, energy treatment, complexation and strengthening treatment on a peptide selenoprotein compound, and the nutrient solution can be widely used for the development and utilization of various selenium-enriched agricultural and sideline products (comprising various food crops, vegetables, fruits, fungi, wild plants, marine food, animal meat and Chinese medicinal herbs). The application of the nutrient solution is as follows: the high-energy composite peptide selenoprotein nutrient solution mother solution is diluted by 6000-8000 times in multiple proportions by adding water, the diluted nutrient solution is irrigated and sprayed to the roots and leaf surfaces of the crops in different growth periods for 3-6 times, and therefore, the selenium-enriched agricultural and sideline products can be obtained.

The invention relates to a sow feeding method of a special wild pig. The method comprises the following steps: (1) feeding sows to reach sexual maturity when the sows are 6-7 months old and are 75-80 kg weight and reach body maturity when the sows are 7-8 months old and 80-90 kg weight and mating the sows; feeding and mating 4-6 non-pregnant sows in each pigsty; feeding each sow at the first trimester of pregnancy in a limiting pigsty or in an independent pigsty, 2-4 sows at the mid trimester of pregnancy in each pigsty and 1-2 sows at the later trimester of pregnancy in each pigsty, and feeding the sows on obstetric tables from 7 days before parturition to weaning; (2) reinforcing sow feeding management, meeting nutritional requirements in the non-pregnant to-be-mating period, the first trimester of pregnancy, the mid trimester of pregnancy, the later trimester of pregnancy and the suckling period, preparing daily rations for the different periods, feeding different feeds, and paying attention to rational matching of green and coarse fodders and concentrated feeds. According to the sow feeding method, the feed and the control for feeding are optimized, so that the sows rut quickly, the farrowing rate is high, normally 12-14 piglets are born by each sow, and the survival rate is over 90 percent.

The invention provides chitosan petrolatum gauze. The chitosan petrolatum gauze is prepared according to the following steps: dissolving a chitosan mixture in a weak acid solution to prepare a chitosan mixed solution; subsequently soaking medical gauze in the chitosan mixed solution to prepare chitosan gauze; soaking the chitosan gauze in a melt petrolatum and paraffin oil mixed solution to prepare the chitosan petrolatum gauze of which the concentration is 1% to 5%. The chitosan petrolatum gauze is a novel medical dressing which is prepared in combination with the advantages of the chitosan and the traditional petrolatum gauze, anti-bacterial, capable of retaining moisture, stopping bleeding and prompting healing of wounds, and low in price. The chitosan petrolatum gauze provided by the invention has the effect of enhancing the original moisture retention properties and also has anti-bacterial properties and unique properties of stopping bleeding, relieving pain, prompting the healing of wounds, reducing formation of scars and the like. The chitosan petrolatum gauze is free of irritation to the human body, free of obvious toxicity, rich in raw materials and low in preparation cost and can be widely applied to wound surface treatment.

A nursery pig feed the following materials by weight: 600-650 parts of corn, 100-150 parts of dehulled soybean meal, 15-25 parts of corn protein powder, 20-30 parts of imported fish meal 65% CP, 27-32 parts of blood plasma protein powder, 23-28 parts of soybean oil, 130-170 parts of premix, 22-26 parts of Radix Pulsatillae, 5-10 parts of Radix Sophorae Flavescentis, 120-180 parts of Radix Astragali, 5-10 parts of Cortex Phellodendri, 10-20 parts of Radix Codonopsis, and 0.5-1.5 parts of mildew preventive. The feed contains complete nutrition including rich proteins, amino acids, vitamins and minerals needed by animals, improves immunity, digestion, absorption and infection resistance of nursery pig, lowers feed-meat ratio, and improves feed repay.

The invention provides a zinc-polypeptide composition, which is prepared from a zinc mineral and an animal material in a weight ratio of (1:1) to (1:5) by hydrolyzing the animal material by protease to obtain polypeptide, and complex-reacting with the zinc mineral. The composition not only contains zinc elements absorbable by human and animal bodies but contains polypeptide component, thus supplementing zinc and enhancing immunity. The composition can be used as a food, a nutritional product, a healthy product or an animal feed additive for supplementing zinc and improving immunity. The materials are selected from natural animal materials, which has low cost, such as low-value agricultural and fishery products or scraps or leftovers of agricultural and fishery products.

The invention discloses a microecological preparation for treating and preventing digestive tract diseases of livestock and poultry and a preparation method and application thereof. the microecological preparation is dried powder obtained by subjecting bifidobacterium, lactobacillus and bacillus to liquid fermentation, centrifuging and low-temperature lyophilizing and compounding with isomaltooligosaccharide and prebiotics. The microecological preparation contains a lot of bioactivators and various viable organisms, and can be used for treating and preventing bacterial diarrhea and lienteric diarrhea of animals, regulating digestion function of the animals, improving body immunity and stress resistance of the animals, promoting animal growing and increasing survival rate of the animals by means of direct feeding, water drinking or adding into feed. The microecological preparation is green and safe, can replace antibiotic drugs to replace intestinal diseases of the animals and has wide application prospect in the field of prevention and treatment of animal diseases.

The invention relates to a compound plant essential oil-type feed additive capable of replacing antibiotics. The additive is capable of regulating intestinal microbial floras, preventing bacterial diarrhea and respiratory diseases, increasing feed intakes, raising body health levels as well as improving animal production performances. The compound plant essential oil-type feed additive is prepared from the following ingredients: cinnamaldehyde, ginger essential oil, carvacrol, geranium essential oil, common origanum oil, folium eucalypti oil and carriers.

The invention discloses a titanium dental implant material and a preparing method and application of the titanium dental implant material. The titanium dental implant material prepared through the preparing method of the titanium dental implant material comprises a base body, a cationic polymer layer, an anion polysaccharide layer-chlorination chitosan-polypeptide A conjugate composite layer and an anion polysaccharide layer-antimicrobial peptide layer composite layer. The titanium dental implant material has good biocompatibility, bacterium resistance, apoptosis resistance and angiogenesis promoting activity, can support adhesion, survival, proliferation and differentiation of various cells, promotes survival, proliferation and migration of vascular endothelial cells, forms a lumen structure of a capillary tube sample and meanwhile inhibits adhesion and survival of periodontal common pathogenic bacteria. The titanium dental implant material has durable and efficient sterilizing and infection resisting capabilities, healing of peripheral bone wounds of the implant can be accelerated, chemical bonding of an implant-bone interface can be achieved, the success rate of oral implantology is increased, the treatment time is shortened, in addition, the preparing method is simple, and a good application prospect is achieved in the oral implantology field.

The invention belongs to the technical field of biomedical engineering, and particularly relates to a chitosan quaternary ammonium salt porcine acellular dermal matrix dressing material and a preparation method thereof. The preparation method of the chitosan quaternary ammonium salt porcine acellular dermal matrix dressing material specifically comprises the following steps: S1, preparing a chitosan quaternary ammonium salt; S2, processing a porcine acellular dermal matrix; and S3, preparing the chitosan quaternary ammonium salt porcine acellular dermal matrix dressing material. The chitosan quaternary ammonium salt porcine acellular dermal matrix dressing material disclosed by the invention completely reserves morphological structures and components of cells, has the characteristic of low antigenicity, and meanwhile can induce fiber-forming cells and vascular endothelial cells with regeneration capacity to grow therein.

The invention discloses a bone tissue engineering scaffold material having anti-infection ability and a preparation method of the bone tissue engineering scaffold material, belonging to the technical field of the preparation of bone tissue engineering biomaterials. The bone tissue engineering scaffold material comprises nano-silver, hydroxylapatite, glucosan and chitosan. The simple preparation method of the invention comprises the steps of: preparing the nano-silver and the hydroxylapatite respectively on the presence of the glucosan, then dispersing the nano-silver and the hydroxylapatite to mixed solution of the glucosan and the chitosan, performing glutaraldehyde crosslinking on the mixed solution and placing the mixed solution in a low temperature refrigerator for prefreezing, and freezing and drying to obtain three-dimensional porous scaffold material. The bone tissue engineering scaffold material has a spatial structure appropriate for the growth of osteoblast and appropriate mechanical properties and degradation property, is also durable and efficient in sterilization and has excellent biocompatibility, thus bone tissue regeneration can be promoted.

The invention discloses a high-efficiency hair care cosmetic and a preparation method thereof, and belongs to the technical field of cosmetic preparation. The cosmetic comprises the following main raw materials: humifuse euphorbia herb, shrubalthea bark, Polygonum aviculare, radix ligustici sinensis, phellodendron bark, Mangnolia officinalis, chrysanthemum flower, gardenia, catechu, chaulmoogra, Cyrtomium fortunei, radix ampelopsis, stemona, pomegranate rind, morning glory seed, southernwood, dark plum, pasqueflower, Lemna minor, tea bran, lysozyme, sericin, hydroxylated soybean lecithin, polyoxyethylene fatty acid ester and modified chitosan. The hair care cosmetic disclosed by the invention has high efficiency and safety, has a remarkable hair care effect, has the favorable effects of sterilization, bacterium resistance and itching relief, improves the infection resistance of hair, can effectively prevent and control phenomena such as head louse appearance and the like on the hair, and exerts favorable hair care action, thereby being worthy of popularization and application.

The invention relates to an in vitro culture kit for T-lymphocyte cells, which fundamentally solves the problems of existing T-lymphocyte cell in vitro culture methods that the used materials and culture time are inconsistent, and the culture periods, quality and quantity of effective cells are different. The technical key points are as follows: the content comprises a coating bottle for inducting the differentiation of the T-lymphocyte cells; a CD3 monoclonal antibody, gamma- interferon and interleukin-1 alpha are pre-coated in the coating bottle; the component of a cell factor A, a cell factor B and a cell factor A for stimulating the division and proliferation of the T-lymphocyte cells is 200000 units of interleukin-2, and the component of the cell factor B is 2 million units of interleukin-2. According to the in vitro culture kit for the T-lymphocyte cells, the composite reagent and materials required for the in vitro culture of the T-lymphocyte cells are combined together in a standard way, all the operation is standardized and modularized, so that not only is the working efficiency improved, but also the cell quality and yield difference caused by the operation of different people is reduced.

The invention belongs to the technical field of medical biological materials and discloses a compound biological patch for repairing abdominal wall defects. The compound biological patch is prepared from a biological patch layer and a bletilla striata fiber mesh layer which covers the surface of one side of the biological patch layer, wherein the bletilla striata fiber mesh layer is an electrospunnano-grade bletilla striata fiber mesh. According to the compound biological patch disclosed by the invention, the bletilla striata fiber mesh layer is combined with a traditional biological patch coating film, so that the anti-infection capability and the wound repairing capability of the compound biological patch are effectively improved; meanwhile, after the compound biological patch is implanted into an organism, the mechanical strength change is higher than needed mechanical strength all the time and tissue reconstruction can be accelerated; existing technical bottlenecks of the biological patch are conducive to solving and the treatment effect of repairing the abdominal wall defects is effectively improved.

The invention provides a special clinical nutritional formula for gynecological inflammation. The special clinical nutritional formula comprises the following components in parts by weight: 14-30 parts of protein, 1-10 parts of fat, 45-65 parts of carbohydrates, 5-10 parts of dietary fibers, 0.5-1.5 parts of major elements, 0.008-0.05 part of trace elements, 0.008-0.02 part of fat-soluble vitamins, 0.09-0.28 part of water-soluble vitamins, 0.05-2 parts of dietary essence, 0.5-3 parts of medicinal and edible components and 0.005-2 parts of new resource food. The invention also provides a preparation method of the nutritional formula. The special clinical nutritional formula is capable of improving the body functions of patients, strengthening nutrients, improving body immunity to avoid repeated attack of gynecological inflammation and simultaneously relieving the symptoms of gynecological inflammation.

The present invention relates to a feed additive, an antibiotic-free feed and an application of the feed. The feed additive comprises the following components in parts by mass: 0.02-0.04 part of probiotics, 0.1-0.3 part of egg powder, 0.02-0.05 part of plant essential oil, 0.50-1.00 part of an organic acidifier, 0.10-0.15 part of a compound enzyme preparation and 1.0-1.5 parts of a yeast extract. The components are cooperated together to play a synergistic role. By using the antibiotic-free feed containing the feed additive to conduct a feeding for a period of time, immunity of nursery pigs is improved. In a condition of a basic same feed intake, an average daily weight gain of the nursery pigs eating the feed containing the feed additive is obvious higher than that in a control group.

A process and equipment for purifying blood includes such steps as centrifugal separation of blood cells from blood plasma, and removing fat from blood plasma through condensing, thawing, Ca ion inducing, freezing, warm dissolving and depositing, radiating the plasma by ultraviolet ray and laser quantum in vibration and stirring state while magnetizing and aerating. It can improve the rheopectic nature and lalance effect of blood.

The invention provides a biological repair tablet for endocranium and a preparation method thereof. The repair tablet uses small intestine submucosa tissues of inbred line animals without cell and DNA (deoxyribonucleic acid) components as the raw material, completely reserves the extracellular matrix component and structure, and has a micropore structure. The preparation method of the repair tablet comprises the following operation steps: determination of animal source, pretreatment and rough cleaning of small intestine tissues, virus inactivation, cell removal, DNA removal treatment, formation, packaging and sterilization. The biological repair tablet for endocranium prepared by the method uses an inbred line animal as an animal source, and thus, the hereditary features are pure, stable and uniform, thereby radically ensuring the stability and uniformity of different batches of products; and the biological repair tablet for endocranium has fewer animal source DNA residues, completely reserves the three-dimensional structure of natural ECM, and has the advantages of low immune source property and high infection resistance.

The invention discloses a zinc-polypeptide complex. The complex is prepared through animal origin and inorganic zinc at a weight ratio of (1:1)-(1:5). The preparation method of the complex comprises the following steps: adding polypeptide produced by hydrolyzing with alkaline protease or bacillus subtilis neutral proteinase to the animal origin; then coordinately reacting with inorganic zinc to obtain the complex, wherein the inorganic zinc is zinc oxide, zinc chloride or zinc carbonate, and zinc oxide or zinc carbonate is better; the animal origin is low-value fish and shellfish products and leftovers or waste produced by processing fish and shellfish. The invention also discloses application of zinc-polypeptide complex in preparation of medicines for preventing and controlling virus, inhibiting the growth of a cancer cell, enhancing the anti-infection capability of an animal to pathogene, and reducing the incidence of infectious diseases.

The present invention discloses one kind of adjuvant for pig vaccine and its preparation process and constituted pig vaccine. The gene adjuvant for pig vaccine is adjuvant including pig gamma-interferon gene (pIFN-gamma), or recombinant plasmid pcDNA-pIFN-gamma of animal cell expression plasmid pcDNA3.1 and pig gamma-interferon gene (pIFN-gamma), or the combination of pcDNA-pIFN-gamma and No. 206 adjuvant. The pig vaccine is composition of pigí»s cysticercus-resisting vaccine composition; pigí»s deactivated foot-and-mouth disease virus vaccine and the gene adjuvant. The gene adjuvant of the present invention is prepared through gene cloning, recombination, recombinant plasmid proliferation, extraction and purification and other processes.

A piglet feed comprises the following materials by weight: 600-630 parts of corn, 60-80 parts of wheat bran, 60-70 parts of dehulled soybean meal, 15-30 parts of imported fish meal 65% CP, 100-200 parts of nursery pig premix, and 1-1.5 parts of mildew preventive. The feed can effectively improve piglet weaning syndrome, effectively reduce diarrhea occurrence after piglet weaning, improve piglet immunity, promote piglet intestinal absorption and ingestion amount, increase daily weight gain, and supplement daily essential nutrition elements for piglet; and is a non-toxic, harmless and green feed.

The invention relates to an miR-29 absorption sequence, an absorption carrier and uses thereof. The miR-29 absorption carrier carries expression cassettes 5'to 3' sequentially comprising the following elements: a) an II-type promoter; (b) an indication protein coding sequence; (c) an miR-29 absorption sequence which is repeated for 4 to 10 times and is a partially complementary or completely complementary sequence to miR-29; and (d) an optional enhancer sequence. The invention also provides application of the absorbent carrier and a pharmaceutical composition containing the carrier. The miR-29 absorption carrier can be used for preventing and treating inflammatory caused by intracellular bacterial infection, Th1-type reaction, tuberculosis and other diseases.

The invention relates to an animal fodder, in particular a gen-seng health feed addictive which is prepared from gen-seng corner material powder and mulberry leaves powder through a finite proportion. The prepared fodder is safe and nuisance free, it produces no drug resistance and tolerance, nor any residual hazards.

The invention relates to infant formula milk powder capable of promoting the development of the intestinal mucosal immunity function of a newborn and belongs to the technical field of infant formula milk powder production.The infant formula milk powder contains necessary substances such as protein, lactose, lipids, vitamins and minerals, and each 100g of the infant formula milk powder also contains 200-300mg of lysozyme and 3-5g of lactoferrin.The infant formula milk powder has the advantages that the infant formula milk powder uses breast milk as the reference, and the lysozyme and the lactoferrin are specially added according to the physiological and nutritional features of the newborn of 0-28 days; experiments prove that the intestinal structure, immunocompetent cell number and bacterial flora distribution conditions of the mice eating the infant formula milk powder are evidently better than those of a control group, and accordingly the infant formula milk powder can evidently improve the intestinal mucosal immunity function of the newborn.

The invention relates to a microecological preparation used for improving penaeus vannemei immunity. The preparation comprises bacillus subtilis, bnfillus licheniformis, and fermentation auxiliary materials. The components are composed according to a weight ratio of 3-8:2:1, such that the microbial preparation is prepared. The microbial preparation provided by the invention contains two high-quality effective bacteria. The strains are strictly selected and cultivated according to microecological regularities. The high quality of the strains is ensured, and viable bacteria content is high. The shelf life of the preparation reaches 24 months. The microbial preparation has good microecosystem regulating and immunity enhancing functions, and especially has substantial function in improving penaeus vannemei immunity.

A wheat piglet feed comprises the following raw materials, in parts by weight: 60-65 soybean meal, 200-250 oat flour, 25-30 sugar, 60-65 whey powder, 250-300 whole soybean meal, 40-50 Hamlet protein, 50-55 plasma protein, 300-320 puffed corn flour, 0.2 Va, 0.15 Vd, 0.25 Ve, 0.0140-0.02 copper, and 0.0120-0.02 iron in each unit. The feed can effectively improve syndrome on the piglets after weaning, effectively reduce the diarrhea rate of the piglets after weaning, improve the immunity of the piglets, promote the intestinal absorption of the piglets, and improve the food intake of the piglets, so as to improve the daily gain in weight and supplement nutrients required by the piglets per day, thus the feed is a non-toxic harmless, green feed.

The invention provides an anal fistula biological suppository and a preparation method thereof. The anal fistula biological suppository uses small intestine submucosa tissues of inbred line animals without cell and DNA (deoxyribonucleic acid) components as the raw material, completely reserves the extracellular matrix component and structure, and has a micropore structure. The preparation method of the anal fistula biological suppository comprises the following operation steps: determination of animal source, pretreatment and rough cleaning of small intestine tissues, virus inactivation, cell removal, DNA removal treatment, formation, packaging and sterilization. The anal fistula biological suppository prepared by the method uses an inbred line animal as an animal source, and thus, the hereditary features are pure, stable and uniform, thereby radically ensuring the stability and uniformity of different batches of products; and the anal fistula biological suppository has fewer animal source DNA residues, completely reserves the three-dimensional structure of natural ECM, and has the advantages of low immune source property and high infection resistance.

The invention discloses serratia marcescens ZJH20098. The officinal bacterium prodigiosum lipopolysaccharide produced at present has serious side effects, such as pyrogen and allergic phenomena. Besides the unspecified process, the main reasons are as follows: the strain is not explicitly stipulated, the mutation is generated by instability, and the functional component change is caused by extraction. The strain provided by the invention is preserved in the China General Microbiological Culture Collection Center (CGMCC) with the preservation number of CGMCC No.4010; and as the strain is collected from the bodies of clinical infected patients, and is a high-activity strain obtained through separation, purification, physical mutagism and optimization, the serratia marcescens ZJH20098 provided by the invention is used as a raw material for producing 'bacterium prodigiosum lipopolysaccharide' for human or livestock use.

The invention provides a piglet feed which comprises the following ingredients: by weight, 20-30% of corn flour, 10-20% of soybean cake powder, 10-20% of wheat bran, 10-15% of domestic fish meal, 0.5-0.8% of salt, 3-5% of haw powder, 3-5% of yeast powder, 0.6% of composite trace elements and 0.6% of multivitamins. The invention provides the piglet feed which has comprehensive nutrients, contains no hormone or harmful component residues, can be used to raise immunity, digestion-absorption function and anti-infective ability of piglets and greatly minimize death rate of piglets, can meet the growth requirement of piglets, is not excessive in amount, will not cause wasting and has remarkable economic benefit.

The invention provides an artificial biological tendon and a preparation method of the artificial biological tendon. Small intestinal sub mucosa tissues of inbred strain animals are adopted as raw materials of the artificial biological tendon and are removed with cell components and deoxyribonucleic acid (DNA) components, extracellular matrix components and structures are completely reserved, and the artificial biological tendon has a cellular structure. The preparation method of the artificial biological tendon comprises the following operation steps of: determining animal sources, preprocessing small intestine tissues, rough cleaning, viral inactivating, removing cells, clearing DNA, forming, packaging and sterilizing. The inbred strain animals are served as an animal source of the artificial biological tendon prepared by the method and have pure, stable and unite genetic characteristics, the stability and uniformity of different batches of products are basically ensured, the DNA residue of the animal source is small, the three-dimensional structure of the natural extracellular matrix component (ECM) is completely reserved, and the artificial biological tendon has low immunogenicity and strong anti-infection capability.