37results about How to "High relaxation efficiency" patented technology

The invention discloses the preparation and the application of a superparamagnetic carbon nanotube contrast agent, belonging to the technique magnetic resonance imaging. A traditional magnetic resonance imaging technique has small signal strength difference among benign tumor tissue, malignant tumor tissue and normal tissue and cannot achieve the purpose of accurate diagnosis. A multi-wall carbonnanotube and ferrocene are uniformly mixed to prepare a superparamagnetic multi-wall carbon nanotube by a high-temperature thermal decomposition method; then, after anionic polymers and cationic polymers are assembled and packed by layers, a water-soluble multi-wall superparamagnetic carbon nanotube, the surface of which has amino groups, is prepared and is connected with targeting agent folic acid by chemical bonds to further functional operation; and the water-soluble multi-wall superparamagnetic carbon nanotube is used as a targeting nuclear magnetic resonance contrast agent transfected tocervical cancer Hela cells cultured in vitro for enhancing MRI image effect. The invention has the advantages of simple preparation method of the contrast agent, small toxicity, high relaxation efficiency, good biological compatibility, suitability of various biological systems, good imaging effect and convenient diagnosis.