The invention discloses a similar EDTA ligand namely 2,2',2'',2'''-((3-(3,4-dihydroxyphenyl)
propane-1,2diyl)
ethylene diamine tetraacetic containing O-phenolic hydroxyl, a non-
gadolinium paramagnetic
metal coordination compound namely a magnetic
resonance contrast agent based on the ligand, a non-
gadolinium metal agglomeration body namely a magnetic
resonance contrast agent, a preparation method of the similar EDTA ligand, a preparation method of the non-
gadolinium paramagnetic
metal coordination compound namely the magnetic
resonance contrast agent, and a preparation method of the non-gadolinium metal agglomeration body namely the magnetic resonance contrast agent. The 2,2',2'',2'''-((3-(3,4-dihydroxyphenyl)
propane-1,2diyl)
ethylene diamine tetraacetic is prepared for the first time, and the ligand combines the advantages of two structures of the O-phenolic hydroxyl and the EDTA, so that the non-gadolinium magnetic resonance contrast agent based on the ligand has high relaxation efficiency, good water
solubility and good structure stability. Compared with a Gd type contrast agent used clinically, the non-gadolinium magnetic resonance contrast agent based on the ligand has the advantages that an order metal agglomeration body namely the contrast agent is self-assembled through coordination, the
MRI imaging effects are better, more details can be displayed, and accurate analysis basis is provided for diagnosing multiple diseases.