The invention discloses a wrinkle-resistant dyeing and finishing process of a ramie fabric. The process includes the following steps that S1, pretreatment is performed; S2, wrinkle-resistant finishingis performed, wherein the ramie fabric obtained through the pretreatment in the step 1 is immersed in finishing liquid at 45-55 DEG C, the bath ratio is 1:25:35, immersion and rolling are performed twice respectively, the rolling rate is 80-95%, pre-drying is performed at 70-90 DEG C, steaming is performed under humidity at 110-120 DEG C, and drying is performed after water washing at 60-70 DEGC; S3, reactive dyeing is performed, wherein the ramie fabric obtained through wrinkle-resistant finishing in the step 2 is immersed into dyeing liquid formed by reactive dye, the bath ratio is 1:(20-30), the temperature is increased to 40-50 DEG C, heat preservation is performed, dyeing is performed, the temperature is increased to 60-80 DEG C, an alkaline agent is added, heat preservation is performed, the temperature rises to 90-100 DEG C, heat preservation and dyeing are performed, and after the temperature is reduced to room temperature, water washing, soaping and drying are performed insequence. The invention further discloses the ramie fabric. Quaternary ammonium salt of chitosan, oxidized microcrystalline cellulose, metal oxide sol and sodium tartrate cooperate and serve as a wrinkle-resistant finishing solution of the ramie fabric, through cooperation with wet steaming, cross-linking of ramie fibers is effectively promoted, and the wrinkle-resistant performance is improved.