59results about How to "Effective sustained release" patented technology

The invention discloses a method for preparing sphere-like mesoporous silica. The method comprises steps of successively adding quantitative CTAB (cetyltrimethyl ammonium bromide) and DDAB (dimethyl dioctadecyl ammonium bromide) into 30-35 DEG C distilled water and dissolving, adding a little ammonium hydroxide, 2 hours later, adding TEOS (tetraethyl orthosilicate), stirring constantly and reacting for 24 hours so as to obtain white precipitate, transferring the white precipitate into a reaction kettle, standing in an incubator, then suction filtering, washing, drying, grinding and calcining so as to obtain the sphere-like mesoporous silica with wormlike pore canals. By utilizing a single / double cationic surfactant composite template, the method can prepare the 90-100nm sphere-like mesoporous silica which has uniform size distribution, is uniformly distributed, and has stable structure, the pore canal is obvious and is 2-3nm, the method is widely used, has mild reaction conditions, has no toxicity and has high yield.

The invention discloses a humic-acid-containing diammonium phosphate neutralization and activation one-step production technology which particularly includes the steps: (1) primarily crushing and drying weathered coal and brown coal and then secondarily crushing the coal to obtain humic acid mineral powder (HA); (2) mixing and dispersing wet-process phosphoric acid and the humic acid mineral powder, pumping the wet-process phosphoric acid and the humic acid mineral powder to a tubular reactor, neutralizing and concentrating the wet-process phosphoric acid, the humic acid mineral powder and ammonia gas formed after liquid ammonia gasification, and then performing slurry-spraying granulation to obtain humic-acid-containing diammonium phosphate. The production technology can be directly implemented on an original production line without changing the technology or changing overall technological process, an adding method is simple and uniform, products are controllable, investment is less,the production process is clean, and the problem of blockage of a tubular reactor in a traditional technology is solved. The batching proportion of the humic acid mineral powder and the wet-process phosphoric acid can be adjusted, and the technology controllable products are uniform and stable. The humic acid content of the produced products can reach 1-3%, plant growths can be effectively stimulated, and agricultural sustainable development is facilitated.

The present invention relates to one kind of compound triptolide alcohol preparation for being injected into articular cavity to treat osteoarthritis. It includes triptolide alcohol solution of 1*10<-4> to 5*10<-2> mg / ml concentration and gel liquid mixed in the volume ratio of 1 to 1-9. It has medicine slow releasing effect, and this can prolong the action period of medicine, reduce consumption of triptolide alcohol and lower the toxic side effect of the medicine. It can inhibit the further development of osteoarthritis in early and middle phase, improve the environment inside the joint and promote the regeneration and repair of articular cartilage to reach the aim of cure osteoarthritis.