The invention discloses a uniform operation and maintenance method and device for a plurality of operating systems of a computer. All the operation of the device is finished between an operation and maintenance operation desk and a host proxy end. The device comprises the host proxy end, a protocol analyzing unit, a file system converting unit, a process system converting unit, a service converting unit, a format converting unit, a code converting unit, a compatibility checking unit and the operation and maintenance operation desk, wherein the host proxy end runs on a host, and is used for executing an operation and maintenance command; the protocol analyzing unit is used for finishing the analysis and interaction of a protocol; the file system converting unit is used for finishing data format conversion during file operation; the process system converting unit is used for finishing data format conversion during process operation; the service converting unit is used for finishing data format conversion during service operation; the format converting unit is used for finishing time data format conversion; the code converting unit is used for finishing language code conversion; the compatibility checking unit is used for checking and converting reserved words, disabled words, formats and file system descriptors of the operating systems; the operation and maintenance operation desk interacts with a user, and is communicated with the host proxy end to finish interaction and result demonstration. By adopting the uniform operation and maintenance method and device, the difficulty and workload in maintenance of a plurality of operating system are lowered effectively, and the stability and reliability are realized.