123results about How to "Aids in diagnosis" patented technology

The invention belongs to the fields of gene engineering and oncology and discloses a serum / plasma miRNA marker associated with breast cancer and application thereof. The marker is a combination of miR-16, miR-25, miR-222 and miR-324-3p. The maker and primers thereof can be used for preparing a diagnosis kit and assisting early diagnosis of the breast cancer.

The invention belongs to the technical field of wind tunnel test apparatus, and specifically relates to a wind tunnel double light path schlieren flow field display apparatus. The wind tunnel double light path schlieren flow field display apparatus includes a fiber coupling LED color light source, a condenser set, a spectroscope, a planar mirror, an optical window, a wind tunnel test model, a spherical reflector, a wind tunnel test section, a cutter edge, an imaging object lens and a camera, wherein the wind tunnel test section is a vacuum sealed compartment; and the test model and the spherical reflector are successively arranged in the wind tunnel test section. The wind tunnel double light path schlieren flow field display apparatus has the advantages of being simple in structure, beinglow in cost, being preferable in the flow field display effect, and being convenient for operation. The wind tunnel double light path schlieren flow field display apparatus solves the flow field display problem which cannot be solved by a conventional schlieren and glow discharge apparatus for nearly continuous flow to rarefied transitional flow (the corresponding flow field static pressure is 100Pa-20Pa and the corresponding test Mach number is about M8-M12). The wind tunnel double light path schlieren flow field display apparatus also solves the problem which is not preferably solved for more than 40 years, that is, the double light path schlieren flow field display apparatus is easy to generate flow field image ghosting.

The invention relates to an ERBB signal pathway mutation targeted sequencing method for the prognosis evaluation of gallbladder carcinoma and provides an application of an ERBB signal pathway mutation targeted sequencing reagent / kit for gallbladder carcinoma patients. In the invention, the whole-genome exon technology is adopted for performing mutation target sequencing of the ERBB signal pathway of a gallbladder carcinoma patient; and in combination with the pathological clinical data of the gallbladder carcinoma patient, the Kaplan-Meier survival curve analysis indicates that the lifetime of the patient after operation is closely related to the gene mutation of the ERBB signal pathway, and the multiple-factor analysis of Cox risk regression model indicates that the gene mutation of the ERBB signal pathway can serve as an independent prognosis factor of gallbladder carcinoma. The prompt of screening the ERBB signal pathway related gene mutation of the gallbladder carcinoma cancer is favorable to the gene-level diagnosis and parting of gallbladder carcinoma, the establishment of therapeutic target, the prognosis analysis and the like.

Near-infrared Raman spectroscopy can be applied to identify preneoplastic lesions of the bronchial tree. Real-time in vivo Raman spectra of lung tissues may be obtained with a fiber optic catheter passed down the instrument channel of a bronchoscope. Using prototype apparatus, preneoplastic lesions were detected with sensitivity and specificity of 96 % and 91 % respectively. The use of Raman spectroscopy apparatus and methods in conjunction with other bronchoscopy imaging modalities can substantially reduce the number of false positive results.

The invention discloses a system and a method for real-time whole body meridian detection. The system mainly comprises a server, a host and a plurality of sense units. The server is provided with a man-machine interface, a database, an image processing module and at least one display module and is connected with the host and then electrically connected with the sensor units worn on corresponding positions of a human body. The system and the method have the advantages that electronic analog signals of meridian acupuncture points can be sensed rapidly by the aid of multiple sensors arranged in the sense units, are subjected to filtering and amplification and analog to digital conversion and then transmitted to the server via the host, and are turned into graphic digital data convenient to read after processing, so that whole body physiological statuses are monitored in real time, and detection efficiency is improved greatly while medical diagnosis is facilitated.

The invention provides a kit for quantitative detection on a serum amyloid protein A. The kit comprises a horse radish peroxidase marked monoclonal antibody of a serum amyloid protein A, a carrier wrapped by the monoclonal antibody of the serum amyloid protein A, a serum amyloid protein A calibration product, and a chemiluminiscence substrate. A preparation method of the kit comprises the following steps: marking the monoclonal antibody of the serum amyloid protein A by using horse radish peroxidase; wrapping the carrier by the monoclonal antibody of the serum amyloid protein A; preparing theserum amyloid protein A calibration product by using a pure serum amyloid protein A product; subpackaging the serum amyloid protein A calibration product, the horse radish peroxidase marked monoclonalantibody of the serum amyloid protein A, and the chemiluminiscence substrate under the action of HRP (Horse Radish Peroxidase); preparing a finished product through assembling. The kit provided by the invention is high in sensitivity, good in specificity, high in quantitative detection result accuracy, low in use cost and relatively easy to popularize and apply.

The embodiment of the invention discloses a medical image segmentation method, device, equipment and system, and a computer storage medium. The method can comprise the steps of calling a target detection model to detect a candidate region where a target organ is located from a to-be-segmented medical image; calling a target positioning model different from the neural network model to position a final area where the target organ is located from the candidate areas; and calling a target segmentation model different from the neural network model to segment the final region to obtain a segmentation result of the target organ. By utilizing the technical scheme provided by the invention, full-automatic segmentation of the medical image can be realized, and a doctor can be helped to diagnose.

A peripheral blood exosome-sourced liver cancer diagnosis and prognosis marker is disclosed. The marker is exosome-sourced Rab27A protein and / or Rab27B protein. Through western blot detection, it is found that the positive expression rate of the Rab27A protein in a peripheral blood exosome of a patient with liver cancer is obviously higher than that of a common person, and the negative expression rate of the Rab27B protein in the peripheral blood exosome of the patient with liver cancer is obviously higher than that of a common person. Analysis about the abovementioned experiment results in combination with clinical data shows that content abnormity of the Rab27A protein and the Rab27B protein is significantly correlated to occurrence and development of liver cancer; and survival time of patients with positive expression of the Rab27A protein and negative expression of the Rab27B protein is shortened. The diagnosis and prognosis marker provides a method having higher sensitivity and higher specificity for liver cancer diagnosis and prognosis in clinic.