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76 results about "Sodium butanoate" patented technology

Fermented feed for nursery pig and preparation method thereof

The invention relates to a fermented feed for nursery pigs and a preparation method thereof. The feed is prepared from the following raw materials in parts by weight through fermenting: 400-700 parts of corns, 50-200 parts of soybean meal, 2-6 pats of lysine hydrochloride, 1-10 parts of calcium formate, 1-10 parts of calcium hydrogen phosphate, 0.2-0.5 part of vitamin premix, 2.5-3.5 parts of organic microelement premix, 1-5 parts of micro-ecologic, 0.2-2 parts of complex enzyme preparation and 0.5-2.0 parts of sodium butyrate. With the consideration of improving the digestion utilization rate of the feed for nursery pigs, together with the physiological characteristics of the nursery pigs, directing to the problems in the existing nursery pig feed processing technology, and through introducing the fermentation technology to prepare the feed and adjusting the structure of daily grains, the plant raw material digestion utilization rate is improved, the feed cost is reduced; in the preparation and production of the feed for the stage, the purposes of reducing energy consumption, reducing cost and improving intestinal health of animals and improving the growth rate are realized.
Owner:TONGWEI

Compound feed for adjusting intestinal development of piglets, and application thereof

The invention discloses a compound feed for adjusting the intestinal development of piglets. The compound feed comprises the components: 61-65 parts of corns, 15-20 parts of bean pulp, 3-6 parts of whey powder, 5-10 parts of fish meal, 1-3 parts of glucose, 0.1-0.5 part of an acidifying agent, 0.5-1 part of calcium hydrogen phosphate, 0.5-1 part of limestone powder, 0.1-0.5 part of table salt, 0.1-0.5 part of L-lysine hydrochloride, 0.1-0.5 part of DL-methionine, 0.1-0.5 part of threonine, 1-4 parts of a piglet premix feed, 0.05-0.5 part of an aloe polysaccharide additive and 0.05-0.5 part of sodium butyrate. After weaned pigs are fed by the compound feed for four weeks, the influence of the feed formula to the development of intestinal microflora biota and intestine mucosa can be discussed. The results prove that in an experimental group, the quality of lactobacillus in the duodenum, the middle section of the jejunum and the ileum as well as the total quantity of aerobic bacteria in the middle section of the jejunum is remarkably increased, the villus heights of the duodenum, the middle section of the jejunum and all the sections of the ileum is remarkably increased, and the crypt depths of the duodenum, the middle section of the jejunum and the ileum is remarkably reduces. Therefore, after the aloe polysaccharide and the sodium butyrate with the appropriate proportion are added into the feed for the weaned pigs, the compound feed has the function of obviously improving the intestinal health, and the experimental group has the effect superior to a flavomycin group and a comparison group.
Owner:天津市泰康生物科技有限公司

Synthetic method for penem and carbapenem antibiotic type key intermediate 4AA

The invention relates to a synthetic method for a penem and carbapenem antibiotic type key intermediate 4AA, belonging to the technical field of medicine. The method comprises the following steps of: reacting L-threonine with sodium nitrite-hydrochloric acid to generate a diazo compound; performing an internal nucleophilic substitution reaction on the diazo compound under the action of sodium hydroxide; acidifying to obtain epoxy sodium butanoate; acidifying to obtain epoxy butyrate; reacting the epoxy butyrate with p-methoxyanilinoethyl acetate to obtain a condensation product; generating a quaternary ring compound from the condensation product under the actions of hexamethyldisilazane and lithium amide; and performing hydroxy protection, hydrolysis, oxidative decarboxylation and ozonization deprotection on the ring compound to obtain 4AA. The process has the advantages of readily-available raw material, mild reaction conditions, short reaction time, low pollution, high yield and the like, and is suitable for industrial production.
Owner:CHINA THREE GORGES UNIV

Environment-friendly compound feed for reservoir ctenopharyngodon idellus

The invention relates to environment-friendly compound feed for reservoir ctenopharyngodon idellus and belongs to the technical field of fish feed. The feed comprises 10-15 parts of flour, 2-5 parts of fish meal, 5-10 parts of peanut meal, 3-8 parts of coconut meal, 3-8 parts of rubber seed meal, 3-10 parts of apple seed meal, 15-25 parts of rapeseed meal, 5-10 parts of citric acid waste, 20-25 parts of soybean meal, 1.5-3 parts of monocalcium phosphate, 0.3-0.5 part of decavitamin premix, 0.5-1 part of compound trace element premix, 0.03-0.1 part of mildew preventive, 0.02-0.1 part of glucan, 0.01-0.1 part of mannan oligosaccharide, 0.02-0.1 part of L-malic acid, 0.05-0.1 part of sodium butyrate and 0.05-0.1 part of bile acid. The feed can well promote the healthy development of the gut and thickening of the intestinal mucosa, reduce the adhesion hyperplasia of harmful germs on the gut, improve digestibility, reduce the occurrence of gut diseases, reduce the loss of nutrients and reduce pollution to water.
Owner:TONGWEI

Preparation method and application of composite biological agent for moderate temperature biogas fermentation high content volatile fatty acid in pig manure waste

The invention relates to a composite biological agent for moderate temperature biogas fermentation high content volatile fatty acid in pig manure waste and a preparation method thereof. The compositebiological agent is prepared from methanogen, moderate temperature syntrophism acetate oxidized bacteria, moderate temperature syntrophism propionate oxidized bacteria, moderate temperature syntrophism butyric acid oxidized bacteria, trace element and vitamin. The composite biological agent enables an acidifying biogas fermentation system using pig manure as a raw material to rapidly and effectively recover to produce biogas normally and to run continuously and stably. The invention further provides the preparation method of the composite biological agent. According to the method, raw materials pig manure inoculant and pig manure are optimized and enriched in a culture medium under anaerobic condition at 37DEG C by increasing sodium acetate, sodium propionate and sodium butyrate level by level, then are concentrated, ammonium chloride, magnesium sulfate, potassium chloride, calcium chloride, yeast powder, sodium acetate, sodium propionate and sodium butyrate are added, then the productis packaged and preserved at low temperature so as to prepare a liquid composite biological agent. Further, the liquid composite biological agent can be mixed with auxiliary materials and then is dried under the anaerobic condition at 37DEG C so as to prepare the solid composite biological agent.
Owner:CHANGZHOU UNIV

Water quality acidifying agent for preventing and controlling African swine fever as well as preparation method and application of water quality acidifying agent

The invention discloses a water quality acidifying agent for preventing and controlling African swine fever as well as a preparation method and application of the water quality acidifying agent. The water quality acidifying agent consists of the following components in percentage by mass: 10%-15% of macromolecular organic acids, 30%-35% of micromolecular organic acids, 10%-14% of micromolecular organic acid salt, 1%-3% of chelated copper, 4%-5% of nisin, 3%-5% of an edible fungus extract and the balance of purified water, wherein the macromolecular organic acids include any one of fumaric acid, lactic acid and malic acid, the micromolecular organic acids include two of formic acid, acetic acid, propionic acid and butyric acid, the micromolecular organic acid salt includes one of ammonium formate, ammonium acetate, ammonium propionate and sodium butyrate, chelated copper includes one of citric acid chelated copper and glutamic acid chelated copper, and the edible fungus extract is a shiitake extract or an edible fungus extract. The water quality acidifying agent has strong acidifying capacity, buffering capacity and acidifying durability, has the characteristics of strong sterilization power, wide bactericidal spectrum, capability in improvement of immunity of the organism, wide use range and the like and is capable of efficiently, rapidly and durably preventing and controllingthe African swine fever, and a disinfection effect is not influenced by organic matters at all.
Owner:SHANDONG SINDER TECH +2

Application of sodium butyrate to feed for rice field eels

The invention discloses application of sodium butyrate to a feed for rice field eels, and a feed for the rice field eels. The content of fish meal in the feed is smaller than 35 percent, the content of plant protein sources in the feed is greater than 40 percent, sodium butyrate is added to the feed, and 0.5-1g of micro-capsule sodium butyrate is added to each kilogram of feed. According to the feed, sodium butyrate is added to the feed for the rice field eels in a manner of a feed additive, mainly aiming at the problems of high price of the fish meal, high formula cost, and structural damage of an intestinal tract form and reduced immunity and growth caused by reduced content of the fish meal in an aquatic feed formula and consumption of a large quantity of plant protein sources, the intestinal tract form of the rice field eels is effectively restored, the absorbing capacity of the intestinal track and the immunity of an organism are enhanced, the growth of the rice field eels is promoted, the feed utilization rate is increased, the application of the plant protein sources in an aquatic feed is improved, the feed cost is lowered; meanwhile, the feed is simple in adding manner, low in cost and remarkable in benefit.
Owner:HANGZHOU KINGTECHINA FEED CO LTD +1

Combination of roscovitine and a hdca inhibitor to treat proliferative diseases

A first aspect of the invention relates to a combination comprising roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA). A second aspect of the invention relates to a pharmaceutical product comprising roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA) as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method for treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA) to a subject.
Owner:CYCLACEL

Liquid amino acid and vitamin additive capable of reducing weaning stress of piglets as well as preparation method and application of additive

InactiveCN107996857AReduce feeding stressPromote growthAccessory food factorsWeight gainingDipeptide
The invention relates to a liquid amino acid and vitamin additive capable of reducing weaning stress of piglets as well as a preparation method and an application of the additive and belongs to the feed field. The liquid amino acid and vitamin additive comprises alanyl-glutamine dipeptide, sodium butyrate, decavitamin, compound amino acid, xylooligosaccharide, an emulsifier and a preservative. Theliquid amino acid and vitamin additive can increase the nutrient substance digestion rate of piglets, regulate micro-ecological balance of intestinal tracts, improve body anabolism of key nutrient substances, enhance protein synthesis, promote growth performance and increase the nursing survival rate. The preparation method of the liquid amino acid and vitamin additive comprises the steps as follows: an aqueous phase solution and an oil phase solution are prepared, respectively, the aqueous phase and the oil phase solution are mixed, and the liquid amino acid and vitamin additive is prepared.The preparation method is simple and easy to operate. After the drink is used for preparing piglet feed, the feed intake of weaned piglets can be increased, the daily weight gain can be increased, diarrhea rate after weaning can be decreased, and weaning stress of the weaned piglets can be relieved.
Owner:NANCHANG AONONG BIOLOGICAL SCI & TECH +2

Induction medium for cultivating and breeding Allium fistulosum, and induction culture method

The invention provides an induction medium for cultivating and breeding Allium fistulosum. The formula of the culture medium comprises KNO3, CaCl2. 2H2O, (NH4) 2SO4, NaH2PO4.H2O, MgSO4. 7H2O, MnSO4. 4H2O, ZnSO4. 7H2O, H3BO3, KI, Na2MoO4. 2H2O, CuSO4. 5H2O, CoCl2. 6H2O, Fe-EDDHA, a corn stigma extracting solution, casein hydrolysate, inositol, sodium pyruvate, fumaric acid, aspartic acid, glycine,sodium humate, riboflavin, vitamin B1, vitamin B6, D-biotin, choline, salicylic acid, sodium butyrate, paclobutrazol, KT, 6-BA, p-hydroxybenzoic acid, sucrose, maltose and phytagel. The invention further provides an induction culture method of the allium fistulosum medicine, the allium fistulosum medicine is inoculated to the induction culture medium for culture after being uniform magnetic fieldtreatment, the callus induction efficiency of the allium fistulosum medicine can be remarkably improved, and establishment of an allium fistulosum medicine cultivating and breeding system is promoted.
Owner:富阿丽

Enteric sodium butyrate microcapsules as well as preparation method and application thereof

The invention relates to an enteric sodium butyrate microcapsule as well as a preparation method and an application thereof. The enteric sodium butyrate microcapsule comprises an inner core layer anda coating material layer coating the surface of the inner core layer, the inner core layer comprises a sodium butyrate core and an auxiliary material layer wrapping the sodium butyrate core. The enteric sodium butyrate microcapsule preparation provided by the invention does not have rancidity-like smell, is not easy to absorb moisture, has good fluidity and dispersibility, can be slowly dissolvedin intestinal tracts, achieves targeted release of the intestinal tracts, and significantly improves the absorption effect. Compared with common sodium butyrate powder, when the sodium butyrate powderis used as a feed additive for feeding animals, the average daily feed intake and daily gain of the animals can be remarkably improved, the feed-to-weight ratio is reduced, and the diarrhea rate is reduced; the content of harmful bacteria such as escherichia coli in ileum and colons of animals can be remarkably reduced, and meanwhile beneficial bacteria such as lactic acid bacteria and bifidobacteria in the colons and cecum are remarkably increased.
Owner:GUANGZHOU GREAT BIOLOGICAL TECH

Preparation method and application of nanometer sustained release sodium butyrate for feed of grass carp

The invention discloses a preparation method of nanometer sustained release sodium butyrate for feed of grass carp and relates to the technical field of fish feed. The preparation method comprises the following steps: n-butyric acid is added dropwise uniformly to a sodium hydroxide solution, a reaction is performed for 1.5-2.0 h after addition, and a sodium butyrate solution is obtained; auxiliaries comprising 2-3 parts of beewax, 1-2 parts of palm wax, 0.1-0.5 parts of fish oil, 1-4 parts of polyethylene glycol, 0.5-1 part of filler and 1-1.5 parts of a nanometer sustained release carrier are added to the sodium butyrate solution in a mass ratio of the auxiliaries to the sodium butyrate solution being (1-1.5):2; finally, nanometer sustained release sodium butyrate is obtained through spray drying at the temperature of 200-220 DEG C. Nano-embedding is performed on sodium butyrate with a nano-embedding technology, so that the defects that sodium butyrate has odor, is prone to deliquescence, difficult to be used by intestinal tracts and cannot provide energy for the intestinal tracts continuously are overcome; intestinal health of the grass carp is promoted, absorption of nutrients is improved, and the economic benefit for breeding the grass carp is increased.
Owner:CHANGSHA UNIVERSITY

Sustained-release sodium butyrate suitable for aquatic animals and preparation method of sustained-release sodium butyrate

The invention provides a preparation method of sustained-release sodium butyrate suitable for aquatic animals. The preparation method includes the following steps: firstly, uniformly mixing sodium butyrate and a hydrophilic gel framework material to prepare preliminary particles, mixing and dissolving a film-forming material, and spraying the film-forming material to the surfaces of the preliminary particles to form a coating layer to obtain water-soluble framework sustained-release particles; secondly, performing melt mixing on a retardant and sodium butyrate, and performing cold spray granulation to obtain fat-soluble sustained-release particles; and finally, uniformly mixing the water-soluble framework sustained-release particles and fat-soluble sustained-release particles to obtain thesustained-release sodium butyrate suitable for the aquatic animals. The product is prepared according to the characteristics of digestion physiology, living environment and feeding characteristics ofthe aquatic animals, the product adopts the combined technology of the water-soluble framework sustained-release particles and fat-soluble sustained-release particles to control the release site, release time and release amount of the sodium butyrate in intestines of the aquatic animals, and the utilization rate of the sodium butyrate in the intestines of the aquatic animals is greatly improved.
Owner:湖南普菲克生物科技有限公司

Compound additive for improving intestinal tract health of piglets and preparation method thereof and application thereof

InactiveCN107668348AImprove the intestinal immunity of pigletsRepair intestinal mucosaAnimal feeding stuffAccessory food factorsNutrientTryptophan
The present invention relates to a compound additive for improving the intestinal tract health of piglets and a preparation method thereof and an application thereof, and belongs to the field of feeds. The compound additive comprises chlorella vulgaris powder, L-tryptophan, glutamine dipeptide, enveloped sodium butyrate, ethyl vanillin, white carbon black and a carrier. The selected components ofthe compound additive are all safe and free of harmful residues, and the compound additive can better improve immunity of piglets, improve intestinal health, reduce diarrhea rate and promote healthy growth of the piglets. The preparation method comprises the following steps: firstly, the ethyl vanillin and white carbon black are mixed according to ratios, and then the materials are mixed with thechlorella vulgaris powder, L-tryptophan, glutamine dipeptide, enveloped sodium butyrate and carrier. The method is simple and fast, can fully mix the components, and can enable the compound additive to be stale and lasting in aroma. The compound additive is used for preparing feeds for the piglets, and can obviously improve intestinal immunity of the piglets, repair intestinal mucosa, improve intestinal health, promote nutrient digestion and absorption, reduce diarrhea rate, and thus improve growth performance of the piglets.
Owner:GUANGZHOU AONONG BIOTECH +2

Preparation method of two-dimension lithium-doped graphene

The invention discloses a preparation method of two-dimension lithium-doped graphene. The preparation method particularly includes following steps: adding hydrotalcite to a proper amount of a sodium butyrate solution, stirring the mixture, aging the mixture, performing separation and drying to obtain sodium butyrate-modified hydrotalcite, adding the sodium butyrate-modified hydrotalcite to a pentane solution of n-butyl lithium under protection of nitrogen, stirring, drying and grinding the mixture to obtain a powder, heating the powder in a vacuum tubular furnace to 400-600 DEG C under a vacuum condition for calcining the powder for 2-4 h, adding the calcined powder to a hydrochloric acid solution, separating the precipitation, heating the precipitation to 2000-2500 DEG C under the vacuum condition to perform heat treatment for 3-6 h, and cooling the product to obtain the two-dimension lithium-doped graphene. The preparation method is simple in raw materials and is mild in conditions.
Owner:山东一开电气设备有限公司

Sodium phenylbutyrate tablet and preparation method thereof

The invention discloses a sodium phenylbutyrate tablet and a preparation method thereof. Described sodium phenylbutyrate tablet is made up of sodium phenylbutyrate and diluent; Described diluent is filler, binding agent and lubricant; In described sodium phenylbutyrate tablet, described sodium phenylbutyrate and The mass ratio of the diluent is 1:0.2-1.5. The preparation method of the sodium phenylbutyrate tablet comprises the steps of: 1) mixing the sodium phenylbutyrate, the filler and the binding agent to obtain a mixture; 2) preparing the mixture granules and dried to obtain sodium phenylbutyrate granules; 3) mixing the sodium phenylbutyrate granules with the lubricant and then compressing into tablets to obtain the sodium phenylbutyrate tablets. Based on the strong hygroscopicity of the raw material of sodium phenylbutyrate itself and its large size (large proportion of the main drug), there are technical difficulties in the preparation. The present invention provides a product with stable quality, suitable hardness, simple and feasible process, and the dissolution level reaches the reference level. Preparations and sodium phenylbutyrate tablets with high bioavailability have filled the blank of sodium phenylbutyrate preparations in my country.
Owner:BEIJING BAIAO PHARMA
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