A compound, a display panel and a display device are provided. The invention provides a compound with a D-Pi-A type chemical structure. The compound has a structure shown as a chemical formula I, wherein L1 and L2 are independently selected from at least one of a single bond, an alkylene group, a cycloalkylene group, a heterocycloalkylene ring group, an arylene group, a heteroarylene group, a fused arylene group and a fused heteroarylene group; the electron donors D1 and D2 are and independently selected from at least one of alkyl, cycloalkyl, alkoxy, heterocyclic group, aryl, heteroaryl, fused arylene group, fused heteroarylene group, carbazolyl, diphenylamine group, triphenylamine group, acridine group and azine group; RF is selected from any one of-F, -CF3, -CF2H, -CF2CF3 and -SF3. As amain body material in an electroluminescent device, the compound has higher triplet state energy level ET, higher molecular density, higher glass transition temperature and higher thermal stability,so that the balanced migration of carriers is effectively improved, the exciton composite area is widened, and the light extraction efficiency is effectively improved. Therefore, the luminous efficiency and the service life of the device are greatly improved.