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45 results about "Lactococcus garvieae" patented technology

Lactococcus garvieae is a known fish pathogen affecting saltwater fish in the Far East, specifically in rainbow trout, Japanese yellowtail, and grey mullet (Mugil cephalus). This bacteria causes lesions in the vascular endothelium, leading to hemorrhages and petechias at the surface of internal organs. As few as 10 bacterial cells per fish can cause an infection. L. garvieae is isolated in saltwater fish in the Far East and specifically in European Rainbow Trout.

Agent for reducing visceral fat

Disclosed is an agent for reducing visceral fat, which comprises a cell of a lactic acid bacterium, particularly a lactic acid bacterium belonging to the genus Lactobacillus or Lactococcus and / or a culture of the cell as an active ingredient. The agent can ameliorate the disease condition of metabolic syndrome which is a combination of risk factors including hypertension, hyperlipemia, impaired glucose tolerance and the like, and can also reduce the accumulation of visceral fat. Further disclosed is a food / beverage or feed comprising the agent.
Owner:SNOW BRAND MILK PROD CO LTD

Construction method and application of faeG expressing gene engineering probiotic

The invention discloses a construction method and application of a faeG expressing gene engineering probiotic. The method comprises the following steps of: according to the gene sequence and the expression vector plasmid characteristic of a disclosed F4 escherichia coli pilus adhesin faeG, designing a primer which contains a specific endonuclease site; performing polymerase chain reaction (PCR) amplification by taking deoxyribonucleic acid (DNA) of an enterotoxigenic escherichia coli plasmid as a template to obtain a faeG gene-containing segment, linking the segment with an expression vector plasmid pNZ8148 to obtain a recombinant plasmid pNZ8148-faeG, transferring the recombinant plasmid into lactobacillus or a galactococcus cell by using an electrotransformation method to obtain gene engineering probiotic which expresses enterotoxigenic escherichia coli pilus adhesin faeG, expressing under the induction of nisin and analyzing and proving a target gene by SDS-PAGE and Western blot so as to express correctly. A recombinant strain can be used for preventing colibacillus diarrhea of suckling pigs and weanling pigs.
Owner:ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES

Lactic acid bacteria and their cellular components inducing immunoregulatory function, and method of obtaining the same

To provide a microorganism and an ingredient thereof that contribute to prevention and treatment of immune diseases including allergy, autoimmune diseases and inflammatory bowel diseases (e.g., large-intestinal ulcer), a method of effectively selecting the microorganism, and a method of efficiently inducing immunoregulatory cells that play an important role on maintaining immunological homeostasis using the microorganism or the ingredient thereof. The present invention provides a Lactococcus and an ingredient thereof which induce production of IL-10 from mammalian dendritic or spleen cells, a method of obtaining the microorganism or the ingredient thereof by co-culturing a microorganism such as Lactococcus strains with mammalian dendritic or spleen cells to select a microbial cell having a high IL-10 production ability, a method of selecting the microorganism or the ingredient thereof by co-culturing an intestinal epithelial cell with a microorganism such as the lactic acid bacteria and selecting the cells on the basis of a caspase-1 activity and the ability of inducing the production of IL-18, and a food product or material and an animal feeding stuff or medical and pharmaceutical products which contain the lactic acid bacteria as an effective ingredient.
Owner:NAT INST OF AGROBIOLOGICAL SCI +1

Equol-producing lactic acid bacteria-containing composition

The present invention provides an equol-producing lactic acid bacteria-containing composition comprising, as an essential component thereof, a lactic acid bacterial strain belonging to the genus Lactococcus having an ability to utilize at least one daidzein compound selected from the group consisting of daidzein glycosides, daidzein, and dihydrodaidzein to produce equol.Such a composition is effective for the prevention and alleviation of malaise inclusive of climacteric disturbance in middle-aged and elderly women for which no effective prophylactic method or alleviating means has heretofore been available.
Owner:OTSUKA PHARM CO LTD

Lactococcus garvieae and biological feed-additive prepared therefrom

The invention relates to the field of microbial technology, and relates to a strain of Lactococcus garvieae and a feed additive produced therefrom. The feed additive is a solid microbial inoculum prepared from a liquid microbial inoculum through addition of proper nutrient substances, wherein the liquid microbial inoculum is prepared from Lactococcus garvieae SYP-B-301 through fermentation culture in a fermentation cylinder. The feed additive has a wide range of applications in animal husbandry and poultry raising such as pig raising, chicken raising, cattle raising and the like. The feed additive has a plurality of functions, through use of the feed additive, animal immunity after eating can be improved, animal diarrhoea rate and death rate can be reduced, the use of antibiotic drugs can be reduced, drug residues can be eliminated, production efficiency can be obviously improved, the raising cycle can be shortened, and feed can be effectively saved, so that income of farmers can be increased.
Owner:SHENYANG PHARMA UNIVERSITY

Method to improve lactococcus preservation

Lactococcus lactis strains with improved preservation characteristics, and improved acid and bile salt tolerance are disclosed. More specifically, a L. lactis strain having a heterologous trehalose-6-phosphate synthase gene and / or a trehalose-6-phosphate phosphatase gene, results in an accumulation of trehalose in the cytoplasm and / or in the cytoplasmic membrane. A L. lactis strain, having an internal trehalose concentration of at least 10 mg per gram cells (w / w) is disclosed.
Owner:INTREXON ACTOBIOTICS NV
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