526 results about "Ionized radiation" patented technology

The present invention discloses a method for determining the position and / or orientation of a catheter or other interventional access device or surgical probe using phase patterns in a magnetic resonance (MR) signal. In the method of the invention, global two-dimensional correlations are used to identify the phase pattern and orientation of individual microcoils, which is unique for each microcoil's position and orientation. In a preferred embodiment of the invention, tracking of interventional devices is performed by one integrated phase image projected onto the axial plane and a second image in an oblique plane through the center of the coil and normal to the coil plane. In another preferred embodiment, the position and orientation of a catheter tip can be reliably tracked using low resolution MR scans clinically useful for real-time interventional MRI applications. In a further preferred embodiment, the invention provides real-time computer control to track the position of endovascular access devices and interventional treatment systems, including surgical tools and tissue manipulators, devices for in vivo delivery of drugs, angioplasty devices, biopsy and sampling devices, devices for delivery of RF, thermal, microwave or laser energy or ionizing radiation, and internal illumination and imaging devices, such as catheters, endoscopes, laparoscopes, and related instruments.

An angle-responsive sensor, comprising:a radiation detector adapted to detect ionizing radiation;at least one radiation absorbing element arranged to block radiation from reaching said detector in a manner dependent on a relative orientation of a radiation source, said detector and said element, said detector and said element defining an aim for said sensor; andcircuitry coupled to said detector and which generates an output signal which varies as a function of said relative orientation,wherein said detector and said element are arranged to have a working volume of at least 10 cm in depth and having an angular width, such that said signal defines an accuracy of better than 3 mm within one standard deviation, over said working volume.

A method for determining the position and / or orientation of a catheter or other interventional access device or surgical probe using phase patterns in a magnetic resonance (MR) signal. In the method of the invention, global two-dimensional correlations are used to identify the phase pattern around individual microcoils, which is unique for each microcoil's position and orientation. In one embodiment the position and orientation of a catheter tip can be reliably tracked using low resolution MR scans clinically useful for real-time interventional MRI applications. In a further embodiment, the invention provides real-time computer control to track the position of endovascular devices and interventional treatment systems, including surgical tools and tissue manipulators, devices for in vivo delivery of drugs, angioplasty devices, biopsy and sampling devices, devices for delivery of RF, thermal, microwave or laser energy or ionizing radiation, and internal illumination and imaging devices, such as catheters, endoscopes, laparoscopes, and related instruments.

An system for detecting contraband, particularly explosives or other energetic materials. The system includes a source of ionizing radiation that irradiates an item under inspection. The radiation stimulates the emission of RF energy from objects within the item under inspection. The characteristics of the emitted RF energy reveals information about the material composition of the objects. The system detects this emitted RF energy and comparers it to a signature of RF emissions from contraband objects. Apparatus to detect and analyze RF emissions may be constructed as a stand-alone unit or may be incorporated into an imaging system in which the ionizing radiation is used to form an image of the item under inspection. Similarly, the RF analysis may be used, in the first instance, to determine whether an object contains a contraband item or may be used as a second level analysis to clear alarms generated by analysis of images formed by the imaging system.

A hard coat film exhibits excellent scratch resistance and wear resistance, provides the property for preventing attachment of finger prints and the property for removal of finger prints by a simple operation, is excellent in retaining these properties, exhibits excellent solvent resistance and is advantageously used as the hard coat film for touch panels and the hard coat film for protecting various types of display. The hard coat film comprises a transparent substrate film and a hard coat layer disposed at least on one face of the substrate film, wherein the hard coat layer comprises a cured product of a resin composition sensitive to an ionizing radiation which comprises a polymerizable surfactant.

The invention discloses a C4 selective hydrogenation catalyst and a preparation method and use thereof. The saturated hydrocarbon hydrogenation catalyst is prepared by ionizing radiation reduction of a primary metal active component precursor and a secondary metal active component precursor, which are supported by a carrier, wherein the primary metal active component is Pd monomer; and the average diameters of particles of the primary metal active component and the particles of the secondary metal active component are both smaller than 10 nanometers. The catalyst disclosed by the invention has the advantages of avoiding being reduced by hydrogen in advance, along with high activity and selectivity, direct use and the like.

The invention relates to ethylene polymers that are modified by ionizing radiation, prior to article formation, at a temperature less than the crystalline melt temperature and preferably under ambient atmosphere, as well as articles made from said polymers. The irradiated ethylene polymers exhibit enhanced melt strength, tensile strength, impact resistance, tear strength, adhesion to polar substances and thermal stability, decreased elongation, and lower melt flow index, but are easily processed and converted into and onto articles by conventional technologies including injection molding, extrusion, film and bottle blowing and powder coating.

Novel transparent composites composed of single wall carbon nanotubes incorporated into the matrix of a polymer are utilized in services wherein the composites are exposed to ionizing radiation, including galactic cosmic radiation. Accordingly, the composites are useful in deep space applications like space vehicles, space stations, personal equipment as well as applications in the biomedical arts and atom splitting research. The composites can be modified with organic dyes containing at least one phenyl ring and the resulting doped composite is useful as a radiation detector. The preferred polymer is poly(4-methyl-1-pentene).

The invention relates to a system for performing a therapeutic procedure like a HDR brachytherapy. An elongate introduction element is introduced into a body (2), a temperature is determined along the introduction element, and it is determined which part of the introduction element is within the body based on the determined temperature. A therapeutic procedure is performed by using the introduction element depending on the determination which part of the introduction element is within the body (2). This can ensure that the therapeutic procedure is only performed within the body, thereby reducing the likelihood of involuntary affecting, for instance, a patient's outer skin, especially by ionizing radiation which may be used during a HDR brachytherapy.

The present invention provides a method of laser processing of materials, specifically laser induced ablation processes for laser removal of material particularly important in medical and dental applications in which the laser removal of material should be done in such a way as to not damage any of the surrounding soft or hard biomaterial. The ablation process is achieved by impulsive heat deposition (IHD) by direct and specific excitation of short lived vibrations or phonons of the material in such a way as to not generate highly reactive and damaging ions through multiphoton absorption. The heat deposition and ensuing ablation process under prescribed time and wavelength conditions for laser irradiation is achieved faster than heat transfer to surrounding tissue by either acoustic or thermal expansion or thermal diffusion that otherwise would lead to excess heat related damage. The result is that all the deposited laser energy is optimally channelled into the ablation process in which the inertially confined stresses from both photomechanical expansion forces and thermally driven phase transitions and associated volume changes constructively interfere to drive the most efficient ablation process possible with minimal damage to surrounding areas by either ionizing radiation or heat effects. By choosing a specific range of wavelengths, spatial and temporal shaping of infrared laser pulses, the energy can be optimally deposited in a manner that further increases the efficiency of the ablation process with respect to minimizing collateral damage.

An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.

The invention provides a method for treating cancer in a human comprising (a) administering to the human a dose of a pharmaceutical composition comprising (i) a pharmaceutically acceptable carrier and (ii) an adenoviral vector comprising a nucleic acid sequence encoding a human TNF-α and operably linked to a promoter, wherein the dose comprises about 4×107 to about 4×1012 particle units (pu) of adenoviral vector, at least once in a therapeutic period comprising up to about 10 weeks, (b) administering a dose of ionizing radiation to the human over the duration of the therapeutic period, and (c) administering a dose of one or more chemotherapeutics to the human over the duration of the therapeutic period, whereby the cancer in the human is treated.

A transparent film comprises: a transparent support; and a hard coat layer on the transparent support, wherein the hard coat layer is a layer which is obtained by: applying on a transparent support an applying composition comprising an ionizing radiation curable compound and at least one kind of active halogen compound; drying; and hardening by irradiation of ionizing radiation.

An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.

An element, particularly a transparent element, including at least one glass element, configured as a protective glass against ionizing radiation and / or UV radiation, wherein at least a portion of the surface of the glass element is covered by a film that includes a substance that can be switched into at least two states.

Methods are provided for close-range intraoperative, endoscopic and intravascular detection and treatment of lesions, including tumors and non-malignant lesions. The methods use antibody fragments or subfragments labeled with isotopic and non-isotopic agents. Also provided are methods for detection and treatment of lesions with photodynamic agents and methods of treating lesions with a protein conjugated to an agent capable of being activated to emit Auger electron or other ionizing radiation. Compositions and kits useful in the above methods are also provided.

The present invention provides a process for producing a polysilsesquioxane graft polymer (1) which includes applying ionizing radiation or heat to a mixture including a polysilsesquioxane compound (2) and a vinyl compound (3), a polysilsesquioxane compound including an iniferter group, and a pressure-sensitive adhesive and a pressure-sensitive adhesive sheet using the polymer. According to the present invention, a process for producing a polysilsesquioxane graft polymer which may be used as a pressure-sensitive adhesive exhibiting excellent heat resistance and cohesive force, and the like are provided. In the formula, A represents a linking group, R1 represents a hydrocarbon group which may have a substituent, R2 represents a hydrogen atom or the like, R3 represents a polar group or the like, R4 represents a hydrogen atom or the like, k1 to k3 represent arbitrary positive integers, 1 to n represent zero or an arbitrary positive integer (excluding the case where “m=n=0”), and Q represents an iniferter group.

A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.