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36 results about "Indirect Pulp Capping" patented technology

Two different types of pulp cap are distinguished. In direct pulp capping, the protective dressing is placed directly over an exposed pulp; and in indirect pulp capping, a thin layer of softened dentin, that if removed would expose the pulp, is left in place and the protective dressing is placed on top.

Adhesive antimicrobial and/or reparative dentin stimulating dental compositions and methods for forming and using such compositions

InactiveUS6071528AEffective and reliable sealEffective and reliable sealingPowder deliveryBiocideAntibiotic YBond strength
Adhesive antimicrobial dental compositions and methods for forming and using compositions are disclosed. The compositions are primarily useful as pulp caps and dentin liners. The composition includes an alkyl methacrylate having an oxyphosphorus group, a polymerization initiator and an antimicrobial agent. The antimicrobial agent can be organohalogens, antibiotics, alkali metal hydroxides, alkaline earth metal oxides and alkaline earth metal hydroxides. The compositions have high dentin tensile bond strength, are stable as a single component or package system, can be polymerized in situ, prevent ingress by microorganisms into an area of a tooth treated with the compositions and can be syringe delivered.
Owner:ULTRADENT PROD INC

Method of manufacturing dental restorations

Method of manufacturing dental restorations using curable compositions including degradable macromonomers having one or more terminal acrylate or methacrylate functionality, a curing composition, a filler composition including bioactive particles of bioactive glass, bioactive glass-ceramics, calcium phosphates, calcium apatites, or mixtures thereof and optionally one or more polymerizable acrylate or methacrylate comonomers. Degradable macromonomers are manufactured from cyclic monomers with compounds having acrylate or methacrylate functionality. Depending on their use, the degradable macromonomer compositions further include one or more organic or inorganic fillers, including a calcium-based compound and / or a radiopacity-imparting agent. The compositions are particularly suitable for root canal sealants, implants, bone cements, and pulp capping materials.
Owner:PENTRON CLINICAL TECH

Preparation method for regenerating dental prosthetic material and acidic amino acid-induced demineralized dental enamel outer enamel prism thereof in situ

The invention discloses a method for regenerating a dental prosthetic material and an acidic amino acid-induced demineralized dental enamel outer enamel prism thereof in situ, and belongs to the technical field of in-situ regeneration of dental enamel outer enamel prisms. The preparation method is as follows: firstly, carrying out surface calcium activation onto a dental enamel surface, i.e., grafting calcium ions; then, forming calcium carbonate stable calcium ions step by step; finally, taking calcium carbonate stable calcium ions as foundation forms to synthesize hydroxyapatite crystals. Amino acid participates in the whole process, concentration of the amino acid added in a two-step process is consistent. The hydroxyapatite crystals deposited on the surface of the demineralized dental enamel are orderly and compact in sequence, and uniform in crystal morphology, so that obvious continued growth tendency of an artificial layer can be seen. The preparation method disclosed by the invention lowers protein extracting cost and harsh restrictions on an application environment, and is wide in prospect. The material prepared by the method disclosed by the invention can be applied to cosmetic dental for filling demineralization gaps, also can be used for repairing early-stage enamel demineralization, and can be used as a combined material for bottom pulp capping pit and fissure sealing, and the like.
Owner:JILIN UNIV

Pre-mixed calcium silicate/magnesium phosphate double-phase composite self-solidification root canal filling material and preparation method and application thereof

The invention provides a pre-mixed calcium silicate / magnesium phosphate double-phase composite self-solidification root canal filling material and a preparation method and application thereof. Magnesium phosphate bone cement powder and at least one calcium silicate compound serve as the main phase, and at least one nonaqueous phase solvent capable of being mixed and dissolved with water and at least one injection-resistance material are added to prepare the root canal filling material with the excellent injectable performance. According to the pre-mixed calcium silicate / magnesium phosphate double-phase composite self-solidification root canal filling material and the preparation method and application thereof, the advantages of magnesium phosphate and calcium silicate materials are combined, so that the solidification time is short, the biological activity is good, and the marginal seal and anti-microbial characteristics are good; and meanwhile clinical application is convenient, and the root canal filling material can serve as the filling material for the field of dental department restoration such as pulp-capping and root canal therapy.
Owner:YANTAI ZHENGHAI BIO TECH

Bioglass-sodium alginate composite biomaterial, kit and application

The invention discloses a bioglass-sodium alginate composite biomaterial, a kit and an application. The kit comprises two components: solid powder and a curing liquid, wherein the curing liquid is a phosphate buffer solution and the powder is calcium, phosphorus and silicon ternary bioglass micro-nanospheres, and the proportion of the solid powder to the curing liquid is 1.1-2.0g / mL. A paste blended by the solid powder and the curing liquid can be cured to form the composite biomaterial with certain mechanical strength and hard tissue repairing property. The biomaterial disclosed by the invention is simple in process equipment, easy to operate and low in cost. The prepared composite biomaterial has good bioactivity, degradation rate and certain mechanical strength and can be clinically used for common pulp capping treatment, oral cavity and orthopedic bone defect repair.
Owner:SOUTH CHINA UNIV OF TECH

Dental cement composition

Disclosed is a dental cement composition made up of ingredients comprising the nanoparticles of dicalcium and tricalcium silicate, bismuth oxide, gypsum, zeolite and strontium carbonate. The dental cement can also be used as bone cement, pulpotomy agent, pulp capping material, dental implant material, perforation repair material, and root-end filling material.
Owner:SAGHIRI MOHAMMAD ALI +2

Kit for adhering biological hard tissues

A kit for bonding to biological hard tissues, containing a phosphorylated polysaccharide, a polyvalent metal salt other than phosphates, and a solvent. The adhesive composition for biological hard tissues provided by the kit for bonding to biological hard tissues is suitably used in for medical uses, such as cement for bones or dental cement. In addition, since the adhesive composition has excellent bio-absorbability, it is useful as fusion materials for artificial joint prosthesis, fusion materials for spine fracture, fusion materials for extremity fracture, filling materials for bone tumors in the region of orthopedics, filling materials and restorative materials at dental caries-defective sites, luting materials for prosthetic restorative materials such as inlay and crown, pulp-capping and lining materials, implant surface treatment materials, periodontal disease therapeutic materials, hyperesthesia preventive materials, dental pulp capping materials, substrates for DDS, substrates for systems engineering, and tissue bonding materials in the dental region.
Owner:UNIV OKAYAMA +1

Pulp capping agent with bioactivity and preparation method thereof

The invention discloses a pulp capping agent with bioactivity and a preparation method thereof. The pulp capping agent with bioactivity comprises dentin extraction solution and dentin powder. The pulp capping agent preparation method comprises the following steps: (1) selecting health dental tissue, cleaning by PBS (Phosphate Buffer Solution) to remove periodontal ligament, cementum and dental pulp, and sterilizing; (2) freezing the dental tissue, and grinding the frozen dental tissue to particles; (3) culturing the dental tissue particles in a medium; and (4) filtering the supernatant from the step (3) to obtain the dentin extraction solution, centrifugally cleaning the cultured dentin particles by the PBS, oven-drying, and grinding to obtain the dentin powders. The pulp capping agent can effectively promote the repair of dentin only by blending the dentin extraction solution with the dentin powder, and applying the mixture at a position close to the dental pulp or at a position at which the dental pulp is exposed, thereby improving the success rate of live-marrow conservation, and providing a new treatment means for patients suffering from accident pulp perforation.
Owner:成都世联康健生物科技有限公司

Pre-mixed strontium silicate-based biological hydraulic cementing paste composition as well as preparation method and application thereof

The invention discloses a pre-mixed strontium silicate-based biological hydraulic cementing paste composition as well as a preparation method and application thereof. The pre-mixed strontium silicate-based biological hydraulic cementing paste takes strontium silicate as a main phase, and is prepared from at least one non-aqueous solvent which can be miscible with water; preferably, the pre-mixed strontium silicate-based biological hydraulic cementing paste is also prepared from at least one calcium phosphate compound and at least one radiopaque material and thereby has excellent injectable property. The material maintains fluid under sealing conditions and carries out hydration solidification hardening after being placed in a physiological environment to contact with physiological body fluid. According to the preparation method disclosed by the invention, by utilizing excellent biocompatibility and bioactivity of a strontium silicate-based material, the strontium silicate-based material is prepared into the pre-mixed strontium silicate-based cementing paste which can be used for medicine and dental dentistry, wherein the dental application relates to the fields of pulp capping, root canal therapy, dental repair and the like.
Owner:BEIJING C ROOT DENTAL MEDICAL DEVICES CO LTD

Pulp capping agent for treating dental pulp lesions as well as preparation method and application thereof

The invention provides a pulp capping agent for treating dental pulp lesions as well as a preparation method and application thereof. Bioactive particles release PO4<3-> ions in an oral environment topromote rapid deposition of Ca<2+> and PO4<3-> on the surface of the material, so that a mineralization layer is formed rapidly; the released metal ions and PO4<3-> play a neutralization role and thus the material has the stable pH value in the body fluid, so that the compatibility with the dental pulp cells is improved and the dental pulp cells are promoted to differentiate into the teeth. The dental pulp capping agent can be used in different ways based on different components. The pulp capping agent that is prepared by compounding of bioactive particles such as phosphosilicate glass, phosphosilicate ceramic and a restorative material causing polymerization covers the surfaces of teeth after being subjected to photo-induced polymerization and solidification, so that rapid formation of dental pulp and tooth tissues is induced and thus dental pulp lesions are treated. Moreover, the pulp capping agent prepared by including solid-phase powder and the liquid phase coats the surface of dental pulp uniformly to treat the dental pulp lesions.
Owner:INST OF CHEM CHINESE ACAD OF SCI

Kit for adhering biological hard tissues

ActiveUS9186433B2Good effectExcellent bio-absorbabilityBiocideImpression capsPhosphateSolvent
A kit for bonding to biological hard tissues, containing a phosphorylated polysaccharide, a polyvalent metal salt other than phosphates, and a solvent. The adhesive composition for biological hard tissues provided by the kit for bonding to biological hard tissues is suitably used in for medical uses, such as cement for bones or dental cement. In addition, since the adhesive composition has excellent bio-absorbability, it is useful as fusion materials for artificial joint prosthesis, fusion materials for spine fracture, fusion materials for extremity fracture, filling materials for bone tumors in the region of orthopedics, filling materials and restorative materials at dental caries-defective sites, luting materials for prosthetic restorative materials such as inlay and crown, pulp-capping and lining materials, implant surface treatment materials, periodontal disease therapeutic materials, hyperesthesia preventive materials, dental pulp capping materials, substrates for DDS, substrates for systems engineering, and tissue bonding materials in the dental region.
Owner:UNIV OKAYAMA +1

Berberine powder-liquid paste applied to direct pulp-capping and preparation method thereof

The invention discloses berberine powder-liquid paste applied to direct pulp-capping. The berberine powder-liquid paste comprises the following raw materials in parts by weight: 30-60 parts of berberine, 30-60 parts of ethyl alcohol, 30-45 parts of soya bean lecithin, 30-45 parts of dichloromethane, 25-40 parts of filler, 20-35 parts of a binder, 20-35 parts of an additive, and 30-60 parts of normal saline, wherein a preparation method thereof comprises the following steps: S1: enabling the berberine in the above parts by weight to be dissolved in the ethyl alcohol, heating in 35-50 DEG C to obtain berberine ethyl alcohol solution; S2: enabling the soya bean lecithin in the above parts by weight to be dissolved in the dichloromethane, mixing to obtain soya bean lecithin solution; and S3: adding the berberine ethyl alcohol solution to the soya bean lecithin solution, evaporating to obtain a phospholipid single-layer film. The berberine powder-liquid paste has triple effects of bacteriostatics, anti-inflammatory and induced osteogenesis, has application potential of repairing inflammatory dental pulp, and is worth popularizing.
Owner:QINGDAO STOMATOLOGICAL HOSPITAL

Dental cement composition

Disclosed is a dental cement composition made up of ingredients comprising the nanoparticles of dicalcium and tricalcium silicate, bismuth oxide, gypsum, zeolite and strontium carbonate. The dental cement can also be used as bone cement, pulpotomy agent, pulp capping material, dental implant material, perforation repair material, and root-end filling material.
Owner:SAGHIRI MOHAMMAD ALI +2

Primer for dental materials and pulp capping agent for dentin regeneration

The present invention provides a dental material primer and a dentin-regenerating pulp-capping agent which exhibit excellent a dentin-regenerating action. The present invention relates to the dental material primer comprising a hydrolyzed ethylene-vinyl acetate copolymer in which collagen is immobilized and the dentin-regenerating pulp-capping agent comprising a hydrolyzed ethylene-vinyl acetate copolymer, in which collagen is immobilized, and a binder.
Owner:MITSUBISHI CHEM CORP

Premixed magnesium phosphate-based dental filling material with stable suspension as well as preparation method and application thereof

The invention discloses a premixed magnesium phosphate-based dental filling material with stable suspension as well as a preparation method and application thereof. The dental filling material with excellent injectable property is prepared from magnesium oxide, at least one phosphate, as well as at least one non-aqueous phase solvent capable of being mixed and dissolved with the water and at leastone irradiation resistance material, wherein the magnesium oxide and the at least one phosphate are taken as main phases; the filling material further comprises at least one type of bioglass. The material maintains a liquid state under a sealing condition; after the material is padded into teeth and is in contact with physiological body fluid, the material is hydrated, solidified and hardened. The premixed magnesium phosphate-based dental filling material with stable suspension is prepared from a magnesium phosphate-based material due to the excellent biocompatibility and biological activityof the magnesium phosphate-based material; the premixed magnesium phosphate-based dental filling material serving as the filling material can be used in the fields of pulp capping, root canal therapy,dental restoration and the like.
Owner:BEIJING C ROOT DENTAL MEDICAL DEVICES CO LTD

Dental pulp capping and pulp retaining paste, method for using pulp capping and pulp retaining paste for dental filling and application of pulp capping and pulp retaining paste

InactiveCN105125414AStable return to normal physiological function stateReduce the number of referralsImpression capsDentistry preparationsCreosoteAdditive ingredient
The invention relates to dental pulp capping and pulp retaining paste, which is prepared from iodine glycerin, iodophor, phenocamphor, creosote and zinc oxide powder, wherein the volume ratio of the iodine glycerin: the iodophor: the phenocamphor: the creosote is (3 to 4):(1 to 2):(1 to 2):(3 to 4); the ratio of the creosote(mL): the zinc oxide powder (g) is 1:(4 to 6); all ingredients are mixed and are prepared into the paste, and thus the dental pulp capping and pulp retaining paste is obtained. The paste has the advantages that after dental pulp is exposed, the nerve burnt killing, the nerve removal and the root canal therapy are not needed; the whole tooth body with the tooth root becomes a dead tooth; the dental pulp capping and pulp retaining paste is directly smeared on the exposed surface of the dental pulp, hard hulls can be formed on the surfaces of dental pulp active body cells; the normal physiological function state of the tooth body is stably recovered; in addition, the treatment process time is shorter; the subsequent consultation times of a patient are fewer; the work intensity of oral doctors is reduced. The pulp capping and pulp retaining paste can be applied to the protection of tooth body dental pulp exposure positions.
Owner:周建洲

Therapeutic Agent for Dentin-Pulp Complex Regeneration

ActiveUS20090118179A1Positively reconstructCosmetic preparationsBiocideDentinBULK ACTIVE INGREDIENT
The present invention provides a therapeutic agent for regenerating a dentin-pulp complex, containing a basic fibroblast growth factor and / or a homolog thereof as an active ingredient. The present invention also provides a pulp-capping agent containing a basic fibroblast growth factor and / or a homolog thereof as an active ingredient.
Owner:OSAKA UNIV +1

Tissue activity promotion type pulp capping agent and preparation method thereof

The invention relates to a tissue activity promotion type pulp capping agent and a preparation method thereof, and belongs to the technical field of pulp capping agents. Periploca forrestii Schltr isground and undergoes alcohol extraction, the obtained alcohol extract is collected and is concentrated, an ethyl acetate component is extracted from the Periploca forrestii Schltr, and the Periploca forrestii Schltr ethyl acetate part has strong osteoclast formation and bone resorption ability inhibition activity, and can improve the activity of cell tissues at the pulp capping position, so the tissue restoration condition is used is improved after the pulp capping agent. A pearl mother material is used as a powder main material, and the main components of the pearl mother powder main materialare calcium carbonate, organic matters and few trace elements, so the pulp capping agent is similar to human skeleton in chemical components and form structure, is nontoxic to local tissues or the whole body, has no rejection reaction, has good biocompatibility and bone affinity, can promote the restoration of root apex periphery tissues, guide the growth of alveolar bone cells and seal apical foramen, and has effectively improved restoration performance.
Owner:常州欧利莱照明有限公司

Dental composition and method of direct pulp capping

A method of direct pulp capping of a tooth including administering a dental composition comprising betamethasone and gentamicin onto an exposed pulp of a tooth, and covering the dental composition present on the tooth with a glass ionomer cement. The dental composition is administered in an amount effective to form a calcification over the exposed pulp. A dental composition having betamethasone, gentamicin, and optionally including a Portland cement. The dental composition is administered to an exposed pulp of a tooth to form a calcification over the exposed pulp.
Owner:IMAM ABDULRAHRNAN BIN FAISAL UNIVERSITY

Preparation method of in-vitro evaluation model of pulp capping material

The invention relates to the technical field of dental reagents and particularly relates to the technical field of in-vitro evaluation of a pulp capping material, and discloses a preparation method ofan in-vitro evaluation model of the pulp capping material. The method is characterized by including steps of: S1) obtaining an in-vitro tooth; S2) separating dental pulp cells; S3) amplifying the cells; S4) adding ECM to perform ball-forming growth; S5) performing continuous induction to prepare a human dentin extract, and adding a culture medium containing the dentin extract into a culture plateto performing continuous induction of cells, thus preparing the human dental pulp organ model. In the method, the human in-vitro dental pulp cells are selected, then cell separation and amplificationand a creative cell ball-forming growth method are carried out, finally continuous induction is carried out. The method is high in cell growth efficiency, and highly simulates the dental pulp organ of human, thereby increasing in-vitro evaluation efficiency and accuracy of the whole material.
Owner:STOMATOLOGICAL HOSPITAL OF CHONGQING MEDICAL UNIV

A kind of notoginseng saponin-hydrogel pulp capping agent material and preparation method thereof

ActiveCN112569122BImpression capsMedical preparationsPolymer scienceReparative dentinogenesis
The present invention relates to a kind of notoginsenoside-hydrogel pulp capping agent material and its preparation method, comprising: step 1, synthesizing gelatin methacrylate (Gel-MA); step 2, preparing load line type ginsenoside R1 (NGR1 ) of gelatin methacrylate and linear ginsenoside R1 composite hydrogel (Gel‑MA / NGR1 composite hydrogel). The beneficial effects of the present invention are: the present invention proposes a photocrosslinkable Gel-MA / NGR1 composite hydrogel as a substitute material for pulp capping agents; the composite hydrogel has strong anti-inflammatory ability and inductive repair property The ability of dentin to form. The physicochemical properties of the photocrosslinkable Gel‑MA / NGR1 composite hydrogel and its efficacy in inducing dentin formation in vitro and reparative dentin formation in vivo were also investigated.
Owner:HANGZHOU HUIBO SCI & TECH CO LTD

Use of mir-93 inhibitors in the preparation of medicines for repairing dentin

The invention discloses a medicine for restoring dentin and belongs to the field of medicine for dentin regeneration. The inventors found through research that the inhibitor of miR-93 has the effect of promoting dentin regeneration. The principle is to increase the expression of histone demethylase JMJD3 by inhibiting miR-93, and regulate the differentiation of dental pulp cells into odontoblasts. and dentin formation. The invention can promote natural dentin regeneration, can be used as a pulp capping agent used in pulp capping, can overcome the problems of diffuse calcification of dental pulp caused by existing pulp capping agents, high technical requirements for operation, and cause tooth discoloration, etc. application prospects.
Owner:SICHUAN UNIV

A kind of biological glass-sodium alginate composite biological material and its kit and application

The invention discloses a bioglass-sodium alginate composite biomaterial, a kit and an application. The kit comprises two components: solid powder and a curing liquid, wherein the curing liquid is a phosphate buffer solution and the powder is calcium, phosphorus and silicon ternary bioglass micro-nanospheres, and the proportion of the solid powder to the curing liquid is 1.1-2.0g / mL. A paste blended by the solid powder and the curing liquid can be cured to form the composite biomaterial with certain mechanical strength and hard tissue repairing property. The biomaterial disclosed by the invention is simple in process equipment, easy to operate and low in cost. The prepared composite biomaterial has good bioactivity, degradation rate and certain mechanical strength and can be clinically used for common pulp capping treatment, oral cavity and orthopedic bone defect repair.
Owner:SOUTH CHINA UNIV OF TECH

Therapeutic agent for dentin-pulp complex regeneration

ActiveUS7807628B2Positively reconstructCosmetic preparationsBiocideDentinBULK ACTIVE INGREDIENT
The present invention provides a therapeutic agent for regenerating a dentin-pulp complex, containing a basic fibroblast growth factor and / or a homolog thereof as an active ingredient. The present invention also provides a pulp-capping agent containing a basic fibroblast growth factor and / or a homolog thereof as an active ingredient.
Owner:OSAKA UNIV +1

Suspension-stabilized premixed magnesium phosphate-based dental filling material and its preparation method and application

Disclosed are a stably suspended premixed magnesium-phosphate-based dental filling material and the use thereof. Magnesium oxide and at least one phosphate, which act as a main phase, at least one non-aqueous phase solvent, which is miscible with water, and at least one radiation-resistant material are used to prepare a dental filling material which can be injected, wherein the filling material may also comprise at least one type of bioglass. Under sealed conditions, the material is kept as a fluid, and is hydrated, solidified and hardened after same has been filled in a tooth and comes into contact with a physiological fluid. Making use of the good biocompatibility and biological activity of a magnesium-phosphate-based material, same is prepared into a stably suspended premixed magnesium-phosphate-based dental filling material, which can be used as a filling material in fields such as pulp capping, root canal therapy and dental repair.
Owner:BEIJING C ROOT DENTAL MEDICAL DEVICES CO LTD

Application of paliurus ramosissimus or paliurus ramosissimus extract in preparation of pulp capping material

The invention discloses application of paliurus ramosissimus or paliurus ramosissimus extract in preparation of a pulp capping material, and belongs to the field of medicine. According to the invention, a fresh paliurus ramosissimus product, a dry crushed paliurus ramosissimus product or the paliurus ramosissimus extract is taken as an active ingredient to serve as the pulp capping material, and the pulp capping material has stable and lasting anti-inflammatory performance, can promote hard tissue formation and improve dental pulp repair capacity, has an obvious effect and is better than clinical common control drugs, and therefore, technical problems that an existing pulp capping material is poor in anti-inflammatory performance and cannot be used for directly capping the pulp of the slightly-inflammatory dental pulp can be effectively solved.
Owner:SICHUAN UNIV

Dental composition and method of direct pulp capping

A method of direct pulp capping of a tooth including administering a dental composition comprising betamethasone and gentamicin onto an exposed pulp of a tooth, and covering the dental composition present on the tooth with a glass ionomer cement. The dental composition is administered in an amount effective to form a calcification over the exposed pulp. A dental composition having betamethasone, gentamicin, and optionally including a Portland cement. The dental composition is administered to an exposed pulp of a tooth to form a calcification over the exposed pulp.
Owner:IMAM ABDULRAHMAN BIN FAISAL UNIV
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