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Dental composition and method of direct pulp capping

a technology of composition and pulp capping, applied in dentistry, medical science, dentistry preparations, etc., can solve the problems of poor sealing ability, dissolution of tissue fluid, and high solubility

Inactive Publication Date: 2019-01-10
IMAM ABDULRAHMAN BIN FAISAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it has major disadvantages including high solubility, dissolution in tissue fluids, and poor sealing ability.
Although clinical studies have also demonstrated that MTA results in good outcomes when used as an indirect or direct pulp-capping material, it has a delayed setting time, poor handling characteristics, and an off-white color.
Pulpal trauma or exposure in conjunction with a pulp-capping procedure can induce inflammation in the pulpal tissue.
However, calcium hydroxide used in the aforementioned study was hard-setting cement form that might have different pulpal response compared with other forms of calcium hydroxide.

Method used

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  • Dental composition and method of direct pulp capping
  • Dental composition and method of direct pulp capping
  • Dental composition and method of direct pulp capping

Examples

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example 1

Materials and Methods

[0071]A randomized clinical trial was approved by the Ethical Committee of the University of Dammam, Dammam, Saudi Arabia (2011037). First premolar teeth scheduled to be extracted for orthodontic reasons were selected for this study. Teeth included in the trial were from patients between 15 and 25 years of age who had no medical or systemic conditions; teeth were also free of periodontal disease, caries, previous restorations, and had normal pulp chambers and closed apices. A pulp status was assessed with cold and electric pulp tests.

[0072]A total of 36 selected premolars were randomly divided by using a statistical randomized treatment table into 4 groups according to the materials used and the duration of follow-up: betamethasone / gentamicin group 1 (BG1 group) (n=9), BG cream with 2-week follow-up; betamethasone / gentamicin group 2 (BG2 group) (n=10), BG cream with 8-week follow-up; mineral trioxide aggregate group 1 (MTA1 group) (n=8), MTA with 2-week follow-u...

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Abstract

A method of direct pulp capping of a tooth including administering a dental composition comprising betamethasone and gentamicin onto an exposed pulp of a tooth, and covering the dental composition present on the tooth with a glass ionomer cement. The dental composition is administered in an amount effective to form a calcification over the exposed pulp. A dental composition having betamethasone, gentamicin, and optionally including a Portland cement. The dental composition is administered to an exposed pulp of a tooth to form a calcification over the exposed pulp.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]The present application is a divisional of U.S. application Ser. No. 15 / 338,658, filed Oct. 31, 2016, the entire contents of which are incorporated herein by reference.BACKGROUND OF THE INVENTIONTechnical Field[0002]The present invention relates to a method of administering a dental composition having betamethasone, gentamicin and, optionally, Portland cement, to a pulp exposed region of a tooth to repair and protect the pulp of the tooth by enabling the formation of a calcification, also known as a dentin bridge.Description of the Related Art[0003]The “background” description provided herein is for the purpose of generally presenting the context of the disclosure. Work of the presently named inventors, to the extent it is described in this background section, as well as aspects of the description which may not otherwise qualify as prior art at the time of filing, are neither expressly or impliedly admitted as prior art against the presen...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K6/00A61K6/083A61K6/06
CPCA61K6/0067A61K6/0606A61K6/0835A61K6/52A61K6/69A61K6/851A61K6/889
Inventor ALSHWAIMI, EMADMAJEED, ABDULALI, AIMAN A.
Owner IMAM ABDULRAHMAN BIN FAISAL UNIV
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