The invention discloses a traditional Chinese medicine preparation for clearing throat, which is prepared from the following raw materials in parts by weight: 1-5 parts of Radix Radix Radix, 1-5 parts of Radix Radix Radix, 1-5 parts of Didantou and 1-5 parts of Licorice. The throat-clearing traditional Chinese medicine preparation has good effects on treating influenza, upper respiratory tract infection, tonsillitis, pharyngitis and the like. According to the in vitro antibacterial experiment, Qinghoukou buccal tablets have a certain inhibitory and killing effect on Staphylococcus aureus, A-hemolytic streptococcus, B-hemolytic streptococcus, Streptococcus pneumoniae and Haemophilus influenzae; Antibacterial experiments in vivo proved that Qinghoukou buccal tablets had a certain protective effect on the death of mice caused by intraperitoneal injection of Staphylococcus aureus. Its antibacterial efficacy in vivo and in vitro provides a theoretical basis for clinical application. The traditional Chinese medicine preparation is based on classification, has strong pertinence, is combined with oral administration and local external application, and has definite curative effect.