75 results about "Rheumatic fever" patented technology

The invention relates to an aspirin solid dispersion, as well as a preparation and use thereof. The aspirin solid dispersion provided by the invention is prepared by taking a methoxy-terminated polyethylene glycol-polylactic acid block copolymer and derivatives thereof, polylactic acid, a polylactic acid-glycollic acid copolymer or polycaprolactone as carrier materials and performing preparation through a solvent method or a hot melting method. According to the preparation method of the aspirin solid dispersion, provided by the invention, hydrolysis of aspirin can be avoided, and toxicity and side effects can be further reduced. The aspirin solid dispersion provided by the invention can be used for relieving fever, relieving pain, resisting rheumatic fever, resisting rheumatism or rheumatoid arthritis and resisting thrombus by subcutaneous or intramuscular injection.

The invention discloses a traditional Chinese medicine spray. The spray is prepared from traditional Chinese medicine raw materials and alcohol, wherein the traditional Chinese medicine raw materials comprise fossil fragments, speranskia herbs, Chinese angelica, common clubmoss herbs, chuanxiong rhizomes, safflower, cassia twigs, acanthopanax bark, radix achyranthis bidentatae, Chinese flowering quince, Gouding, asarum, clematis roots, wild aconite roots, licorice roots, raw sichuan axonite roots, radix angelicae pubescentis, pseudo-ginseng, zanthoxyli, camphor and Illicium henryi Deils. The traditional Chinese medicine spray disclosed by the invention uses more than 20 traditional Chinese medicine materials as the raw materials, and gives play to the function of collaboration. The prepared traditional Chinese medicine spray has the efficacies of promoting blood circulation, dissipating blood stasis, reducing swelling, easing pain, relieving rigidity of muscles and activating collaterals, and can be used for treating various parenchyma damage and rheumatic fever and pain, such as traumatic injury, extravasated blood and swelling, and the treating effect is good.

Recombinant hybrid streptococcal M protein antigens are provided which elicit protective antibodies against Group A streptococci and prevent rheumatic fever. Recombinant hybrid genes which encode the antigen are provided. Vaccine compositions and methods of administering the compositions are provided to elicit immunity against Group A streptococci.

Provided are methods for diagnosing a disease in a subject with a previous streptococcal infection by determining the presence or absence of one or more autoantibodies in a biological sample from the subject, wherein the one or more autoantibodies recognize an antigen from a protein selected from the group consisting of ELAVL2, ELAVL3, ELAVL4, Nova-1, Nova-2, Cdr1, Cdr2; and Cdr3. The presence of such autoantibodies is indicative of a positive diagnosis for a post-streptococcal disease such as PANDAS, post-GABHS glomerulonephritis, rheumatic fever, autism and Syndenham's chorea.

The invention provides a medicine for treating rheumatism and rheumatoid diseases. The medicine is prepared from the following Chinese herbal medicines in part by weight: 9 parts of lucid ganoderma, 7 parts of papaya, 7 parts of notoginseng root, 7 parts of safflower, 12 parts of eucommia bark, 18 parts of common clubmoss herb, 8 parts of Chinese angelica, 11 parts of medicinal cyathula root, 6 parts of liquoric root, 3.5 parts of prepared kusnezoff monkshood root, 4.5 parts of prepared common monkshood mother root, 4.2 parts of scorpion, 12.5 parts of gambir plant, 8 parts of himalayan teasel root, 6 parts of cassia twig, 9 parts of dendrobium, 7.5 parts of ephedra herb, 14 parts of siberian solomonseal rhizome, 7 parts of malaytea scurfpea fruit, 7 parts of east asian tree fern rhizome, 4 parts of little multibanded krait, 6 parts of garter snake, 6 parts of Chinese honeylocust spine, 6 parts of stiff silkworm, 5 parts of frankincense, 5 parts of myrrh, 0.5 part of prepared nux vomica, 8 parts of divaricate saposhnikovia root, 8 parts of tuckahoe and 25 parts of medlar. The medicine has the effects of expelling wind-damp, relieving pain or numbness, nourishing blood, promoting blood circulation, dredging collaterals and nourishing yin, and is suitable for treating symptoms of deadlimb, arthralgia and myalgia, waist-leg weakness, arthrocele, dysarthrosis, sluggish flexion and extension of joints and the like which are caused by anemofrigid-damp arthralgia and rheumatic pyretic arthralgia retention.

The invention discloses Chinese medicine external lotion for treating infantile eczema. In china, the infantile eczema is medically called milk ringworm and also called embryo ringworm. The natural disposition is not tolerant, the skin is tender and lovely, the transformation of the spleen and the stomach is failed, the body of the infant is internally suffered from embryo fire damp heat and is externally invaded by rheumatic fever evil, and the internal reason and the external reason are blocked by the skin so as to cause the disease. According to the Chinese medicine external lotion, the Chinese medicines such as tangut barberry barks, felworts, Guangdong longhairy antenoron herbs, Chinese glochidion leaves, climbing groundsel herbs, sturnus roseus, golden larch barks, sinkiang arnebia roots, agaric, honewort stem and leaf and henry clematis roots are selected and decocted with water to prepare external lotion. A clinical test in hospital shows that the total effective rate is 95.0 percent, and the efficiency is superior to that of a control group.

The invention discloses a traditional Chinese medicine composition for treating a damp-heat type rheumatic fever.The traditional Chinese medicine composition is prepared from, by weight, 25-28 parts of coix seeds, 12-16 parts of rhizomes of Chinese atractylode, 5-8 parts of common curculigo rhizomes, 10-13 parts of cortex phellodendri, 4-8 parts of valerian roots, 7-10 parts of fourstamen stephania roots, 18-21 parts of talc, 10-14 parts of silkworm excrement, 13-16 parts of suberect spatholobus stems, 12-15 parts of rhizoma anemarrhenae and 8-12 parts of almond kernels.The invention further discloses a preparing method of the traditional Chinese medicine composition for treating the damp-heat type rheumatic fever.The prepared traditional Chinese medicine composition is remarkable in treatment effect on the damp-heat type rheumatic fever and can radically treat the rheumatic fever, and relapse is not likely to occur after a patient is cured; the traditional Chinese medicine composition is free of toxic or side effects, simple in prescription, low in price and capable of relieving the treatment burden of the patient.

The invention belongs to the technical field of medicine, and particularly relates to a Zhuang medicine for treating gout and a preparation method thereof. The Zhuang medicine is prepared from, by weight, 25-50 parts of herb of glabrous sarcandra, 15-40 parts of polygonum cuspidatum, 15-40 parts of honeysuckle stems, 15-40 parts of fenbixie, 15-40 parts of plantain herb, 10-30 parts of cynanchum paniculatum, 10-30 parts of garden balsam stems and 3-12 parts of liquorice roots. According to the Zhuang medicine preparation for treating gout, the accessories meeting the medicine standard are added, and medical solid particles or a liquid preparation is prepared. The Zhuang medicine preparation for treating gout is scientific and reasonable in formula, and has the functions of clearing heat and promoting dieresis and dispelling wind and removing obstruction in the meridians, and the clinical application result shows that the Zhuang medicine preparation for treating gout has the effects ofclearing heat and toxins, removing damp toxins, removing wind toxins, relieving swelling, adjusting the water channel and dredging the dragon channel and the fire channel, and has a good effect of treating gout caused by rheumatic fever and damp toxins, wherein gout comprises the symptoms of arthralgia, swelling, scorching hot, inhibited bending and stretching, increasing blood uric acid, uratomaand the like.

A traditional Chinese medicine for remedying the dacryocystitis caused by the upwards attack of the liver-wind damp-heat belongs to the traditional Chinese medicine for remedying the dacryocystitis. The components contain: 3g of angelica tails, 3g of red peony roots, 3g of fineleaf schizonepeta herb spikes, 3g of divaricate saposhnikovia roots, 3g of Szechwan lovage rhizome, 3g of wild chrysanthemums, 3g of unprepared gardenia, 3g of mints, 4.5g of bupleurum roots, 4.5g of weeping forsythia capsules, 6g of honeysuckles and 1.5g of unprepared liquorice. The dosage materials in the prescription are all made from natural traditional Chinese herbal medicines by the traditional processing method. The materials can be easily gotten; the prescription and the preparation method are simple; the expense for preparing the medicine is low. The compatibility of the traditional Chinese herbal medicines is simple; the medicines used in the medicine prescription are all natural herbal medicines which can be conveniently gotten and used; the manufacturing method is simple; the curative effect after being taken is good; the medicine price is cheap, and the medicine is especially fit for people who live at the remote small villages away from villages and towns to use. The treatment expense for the patient with the disease of the dacryocystitis caused by the upwards attack of the liver-wind damp-heat is low, which solves the treatment problem which is caused by low family income, poor living and lack of local medical treatment condition.

The invention provides a traditional Chinese medicinal composition for treating rheumatic fever type psoriasis, belonging to the technical field of traditional Chinese medicinal preparations. The traditional Chinese medicinal composition is mainly prepared from eight medicinal materials including radix scutellariae, herba schizonepetae, divaricate saposhnikovia root, periostracum cicada, rhizoma atractylodis and the like, and is prepared into different dosage forms including capsules, tablets, pills, granules, oral solutions and the like for later use by adopting pharmaceutical equipment. The traditional Chinese medicinal composition has the functions of dispelling wind and clearing heat, as well as eliminating toxins and relieving itching, and is good in effect and convenient to take, as well as safe and effective when used for treating rheumatic fever type psoriasis.

The invention provides medicine and food dual-use wine and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine medicinal liquor. The wine is characterizedby comprising fresh rice wine, root of kirilow rhodiola, radix panacis quinquefolii, radix codonopsis, jujubae fructus, radix glycyrrhizae, the bark of eucommia, herba epimedii, herba cynomorii, theseed of Chinese dodder, the seed of astragalus complanatus, fructus psoraleae, fructus alpiniae oxyphyllae, tuber onion seed, white peony root, radix rehmanniae praeparata, radix polygoni multiflori,radix angelicae sinensis, fructus lycii, fructus mori, rhizoma polygonati, fructus ligustri lucidi, the sporocarp of ganoderma lucidum, fructus crataegi, the rhizome of chuanxiong, radix salviae miltiorrhizae, flos carthami, cortex cinnamomi, fructus rubi and apple. The wine has effects of improving human immunity, resisting fatigue and hypoxia, invigorating the brain and developing intelligence,nourishing liver to improve eyesight, strengthening heart and tonifying spleen, invigorating the kidney and strengthening Yang, promoting blood circulation to remove blood stasis, removing rheumatic fever, and regulating hyperlipoidemia, hypertension and hyperglycemia.

The invention discloses a traditional Chinese medicine composition for treating phlegm-stagnation and heat-arthralgia type rheumatic fever. The traditional Chinese medicine composition is characterized by being prepared from the following medicinal materials by weight: 6-9 parts of herba of zostera marina, 12-15 parts of bulb of picrarrhiza kurroa royle, 10-15 parts of frond of carrageen, 15-20 parts of herba of Abacopteris triphylla, 10-15 parts of luffah sponge, 6-9 parts of Zhejiang fritillary bulbs, 10-15 parts of Indian nightshade roots, 35-40 parts of herba or root of cayratia japonica, 15-20 parts of stem and root of schisandra lancifolia, 20-25 parts of water chestnut roots, 10-15 parts of herba of pilea martinii, 20-25 parts of stem or root of euphorbia humifusa, 12-15 parts of herba of elatostema lineolatum, 6-9 parts of herba of phlegmariurus fordii, 40-45 parts of vitis davidii roots and 3-6 parts of licorice roots. The traditional Chinese medicine composition, disclosed by the invention, is used for treating the phlegm-stagnation and heat-arthralgia type rheumatic fever and is high in effective rate and reliable in treatment effect, and recurrence does not occur any more after cure.

Disclosed is a pharmaceutical composition for preventing or treating TRPV1 activity-related or inflammation-related, diseases or conditions, containing a Maillard peptide separated from well-aged traditional soy sauce as an active ingredient. The Maillard peptide in the present invention functions both as a TRPV1 agonist and a TRPV1 antagonist, and further functions as a TRPV1 activity modulator. Therefore, the Maillard peptide can be used for preventing or treating TRPV1 activity-related diseases such as pain, neurological diseases, urgent defecation, inflammatory bowel disease, respiratory diseases, urinary incontinence, overactive bladder, neurogenic / allergic / inflammatory skin diseases, skin, eye or mucosal irritation, hyperacusis, tinnitus, vestibular hypersensitivity, heart disease, etc. The Maillard peptide can further inhibit COX-2 activity, and therefore can be effectively used for preventing or treating inflammation-related diseases or conditions such as rheumatic fever, influenza, cold, throat pain, headaches, toothaches, sprains, neuralgia, synovitis, rheumatoid arthritis, degenerative arthropathies, gout, ankylosing spondylitis, psoriasis, dermatitis, etc.

The invention discloses red bean and coarse cereal bread. The red bean and coarse cereal bread consists of the following raw materials in parts by weight: 30-40 parts of wheat flour, 6-8 parts of peanut oil, 30-40 parts of soybean meal, 6-10 parts of egg white, 40-50 parts of corn flour, 5-9 parts of honey, 30-40 parts of buckwheat powder, 2-6 parts of mung beans, 20-40 parts of sweet potatoes, 6-8 parts of milk powder, 1-3 parts of baking powder, 40-60 parts of red beans, and 1-3 parts of table salt. According to the red bean and coarse cereal bread disclosed by the invention, the red beans and various coarse cereals are added, so that the red bean and coarse cereal bread is rich in nutrition, can complement multiplex vitamins and protein, has a good health-care efficacy, and can prevent febrile illness, such as colds, dysentery, hepatitis, diabetes, cancer, nephritis, rheumatic fever, chronic tracheitis, high blood pressure and the like, and is favorable for the health of human bodies.

The invention relates to an agkistrodon-containing preparation for gouty arthritis treatment and belongs to the technical field of Chinese herbal medicine preparations. The preparation is prepared from three Chinese herbal medicines including agkistrodon, coix seeds and pseudobulbus cremastrae seu pleiones. The preparation is based on research and treatment principles of traditional Chinese medicine for pathogenesis of gouty arthritis and refers to scientific achievements of modern traditional Chinese medicine theories for Chinese herbal medicine treatment of gouty arthritis, and agkistrodon is adopted to dispel wind and remove obstruction in the meridians and is supplemented with the coix seeds for excreting dampness, removing arthralgia, eliminating toxic materials and removing stasis; the pseudobulbus cremastrae seu pleiones has effects of clearing away heat and toxic materials, reducing phlegm and resolving masses; the three Chinese herbal medicines are compatible, supplement each other, and has functions of dispelling wind, removing obstruction in the meridians, excreting dampness, removing arthralgia, eliminating toxic materials and removing stasis. The prescription is rigorous, accords with traditional Chinese medicine theories and new knowledge of the modern medicine for gouty arthritis and is free of toxic and side effects; the preparation has remarkable curative effects on redness and swelling of joints, heat pain, stiffness, flexion-extension inconvenience due to gouty arthritis as well as inhibition for uric acid formation and further has obvious curative effects on rheumatic fever, rheumatoid arthritis, ankylosing spondylitis and degenerative arthritis.

The invention provides a Zhuang medicine composition with a treatment effect on acute gouty arthritis, Zhuang medicine particles and a preparation method of the Zhuang medicine composition and the Zhuang medicine particles, and relates to the technical field of ethnic medicines. The Zhuang medicine composition is composed of glabrous sarcandra herb, rhizoma dioscoreae hypoglaucae, plantain herb, polygonum cuspidatum, cynanchum paniculatum, garden balsam stem, honeysuckle stem and liquorice, and clinical application results prove that the Zhuang medicine composition has the effects of clearing heat toxin, removing dampness toxin, dispelling wind toxin, relieving swelling pain, adjusting water channels, dredging long channels and fire channels, and has a remarkable curative effect on gout (gout) caused by wind-damp heat toxin. The Zhuang medicine composition and the Zhuang medicine granules based on the Zhuang medicine composition have very good curative effects on arthralgia, redness and swelling, scorching heat, unfavorable flexion and extension, blood uric acid increase, tophus and the like, and particularly, the Zhuang medicine composition and the Zhuang medicine granules based on the Zhuang medicine composition can be used for treating gouty arthritis induced by MSU crystals, and have the characteristics of multiple targets and low toxicity.

The invention provides a traditional Chinese medicine composition for treating osteoarthritis and a preparation method thereof. The traditional Chinese medicine composition is prepared from from the following raw material medicines in parts by weight: 10-20 parts of poria cocos, 5-15 parts of cassia twigs, 2-8 parts of rhizoma atractylodis, 2-8 parts of cortex phellodendri, 2-8 parts of radix stephaniae tetrandrae, 2-8 parts of polyporus umbellatus, 2-8 parts of rhizoma drynariae, 5-15 parts of rhizoma corydalis and 3-9 parts of radix cyathulae. The composition disclosed by the invention has the functions of tonifying spleen, promoting diuresis, dispelling wind, clearing heat, dredging collaterals and relieving pain, and is clinically applicable to patients suffering from rheumatic fever arthralgia in the attack stage of knee osteoarthritis, wherein the patients have the symptoms of swelling, pain, unfavorable flexion and extension and even local pyrexia, redness and swelling of joints, fat and big tongue body with tooth prints, yellow and greasy tongue coating and few pulse strings. When the composition provided by the invention is used for intervening in a rabbit with knee osteoarthritis, results show that the composition can relieve symptoms like joint swelling and skin temperature rise of the rabbit with knee osteoarthritis, improve joint functions, reduce the contents of IL-1[beta], TNF[alpha], PGE2 and NO in joints, relieve synovitis and delay the progress of knee osteoarthritis. Clinical observation results show that the composition provided by the invention has theeffects of relieving swelling and pain and improving joint functions for patients with knee osteoarthritis.

The invention discloses a traditional-Chinese-medicine preparation for treating rheumatic fever and a preparation method thereof and belongs to the field of traditional Chinese medicines. The traditional-Chinese-medicine preparation comprises the following raw materials constituting effective ingredients: xanthium strumarium, fohum aconiti kusnezoffii, white perilla leaf, herb of Chinese arundina, ardisia crispa, syzygium buxifolium, drymoglossum piloselloides presl, lilium brownii, bellflower, radix angelicae, common ducksmeat herb, ramose scouring rush herb, semen boitae, euonymus macropterus, Chinese parsnip root and Chinese mesona herb. The traditional-Chinese-medicine preparation is suitable in compatibility of selected medicines, conforms to the theory of traditional Chinese medicine and pharmacy and modern medicine and pharmacology, has the effects of clearing heat and removing toxicity, alleviating spasm and pain, dispelling wind and promoting diuresis and activating blood and dredging channels, has an obvious treating effect for treating the rheumatic fever caused by the symptoms such as generalized fatigue, anorexia and dysphoria, is convenient to take, safe and reliable, allows fast effect without toxic and side effects and low in cost, and can treat both symptoms and root causes.

The use of 1-MNA or a pharmaceutically acceptable salt thereof for reducing the risk of cardiovascular disease in a subject with a blood or serum CRP level of less than 10 mg / L. The disclosure also discloses the use of 1-MNA or a pharmaceutically acceptable salt thereof in the amount effective for reducing the blood or serum CRP level for the treatment of diseases such as rheumatoid arthritis, colon cancer, breast cancer, lung cancer, infection, inflammatory bowel disease, lupus erythematosus, pneumococcal pneumonia, rheumatic fever, tuberculosis, renal failure, amyotrophic lateral sclerosis,or a combination thereof.

The invention discloses a compound flos lonicerae and fructus forsythiae detoxifying emulsifiable paste for preventing and treating acnes. The emulsifiable paste comprises the following raw materials in parts by weight: 10-20 parts of flos lonicerae, 10-20 parts of fructus forsythiae, 5-15 parts of folium isatidis, 10-20 parts of hedyotis diffusa, 10-20 parts of radix scrophulariae, 5-15 parts of cortex moutan radicis, 5-15 parts of rhizoma smilacis glabrae, 10-20 parts of rhizoma atractylodis macrocephalae, 5-15 parts of herba violae, and 5-15 parts of cortex phellodendri. The compound flos lonicerae and fructus forsythiae detoxifying emulsifiable paste has good treatment effects on patients with skin acnes caused by rheumatic fever stasis, lung-stomach intense heat, latent toxicity and warm pathogen.

The invention discloses a traditional Chinese medicine handmade soap and a preparation method thereof. The handmade soap comprises, by weight, 750-850 parts of a transparent soap base, 50-80 parts ofan ethyl acetate extract part of cortex dictamni, 2-4 parts of glycerol, 10-12 parts of olive oil, 3-5 parts of an ailanthus bark extract, 3-4 parts of a fructus kochiae extract, 2-3 parts of a fructus cnidii extract, 2-3 parts of a chrysanthemum extract, 2-3 parts of a mint extract, 2-4 parts of rhizoma imperatae extract, 2-4 parts of radix sanguisorbae extract, 2-4 parts of lotus rhizome node extract and 1-2 parts of borneol. All the raw materials are sequentially extracted and completely processed to obtain the product. The handmade soap not only can clean skin but also has great functionsof clearing heat to dry dampness and dispelling wind to remove toxin, effectively solve the common skin surface problems, such as skin itch, eczema and rubella, scabies, sores and leprosy, rheumatic fever arthralgia and the like, and makes skin healthy and bright.

The invention discloses a capsule preparation for treating arthritis caused by rheumatic fever. The capsule preparation is prepared from the following main raw materials in parts by weight: 5-15 parts of radix clematidis, 4-14 parts of ligusticum wallichii, 0.5-0.9 part of procaine, 1-3 parts of earthworm, 4-11 parts of ephedra, 8-16 parts of myrrh, 2-7 parts of naproxen, 1-5 parts of acetylsalicylic acid, 3-7 parts of indometacin, 6-10 parts of beautiful sweetgum fruit, 3-9 parts of serrate clubmoss herb, 3-8 parts of the seed of Chinese dodder, 1-6 parts of robust leontice rhizome and root and 4-8 parts of tiger bone-glue. The capsule preparation for treating arthritis caused by rheumatic fever disclosed by the invention has the effects of promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals, strengthening tendons and bones and dissipating blood stasis and relieving pain. The medicinal materials disclosed by the invention are readily available in medicine source and low in cost, most of the selected medicinal materials are mild in medicine properties, and even if the medicine is taken for a long time, the economical and physical burdens of the user are not increased.

Rheumatism is an allergic disease related to group A streptococcus, involves connective tissues of a whole body, is represented as acute or chronic connective tissue inflammation, mainly degeneration and necrosis of collagen fibers. Rheumatism mostly involves heart and joints, and secondly subcutaneous, serosa, blood vessels and brain, and is called rheumatic fever in the acute phase. The invention relates to a medicinal liquor composition for dispelling wind and activating collaterals. The medicinal liquor composition is prepared from the following components: 50-150g of garter snake, 10-50g of ligusticum wallichii, 10-50g of Sichuan papaya, 10-50g of incised notopterygium, 10-50g of radix angelicae pubescentis, 10-50g of obscured homalomena rhizome, 10-30g of radix aconiti preparata, 10-50g of gentiana macrophylla, 20-60g of radix cyathulae, 30-80g of pterospermum heterophyllum and 50-150g of rock candy.

The invention discloses a traditional Chinese medicine composition for treating arthritis caused by rheumatic fever. The traditional Chinese medicine composition is prepared from the following main raw materials in parts by weight: 5-15 parts of radix scrophulariae, 15-25 parts of golden cypress, 10-20 parts of Ligusticum wallichii, 3-5 parts of radix angelicae pubescentis, 4-11 parts of cassia twig, 8-16 parts of Chinese Starjasmine Stem, 7-15 parts of fructus forsythiae, 5-15 parts of Lonicera japonica, 3-7 parts of nux vomica, 6-10 parts of loranthus parasiticus, 3-9 parts of Artemisia anomala, 6-9 parts of ephedra, 0.5-1.5 parts of zaocys dhumnade, 4-8 parts of cynanchum paniculatum, 3-8 parts of dipsacus root and 5-10 parts of pepper. The traditional Chinese medicine composition for treating arthritis caused by rheumatic fever disclosed by the invention has the functions of promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals, strengthening tendons and bones, and eliminating stagnant blood and relieving pains, the medical herbs resource of medicine materials is easily available, the cost is low, the selected materials are mild in drug property, and no economic or body burden is increased for a user with long-term use.

The invention relates to a combination drug powder for prevention and treatment of rheumatic fever-type neurodermatitis, which belongs to the technical field of a health product. The combination drugpowder is composed of 9 bulk drugs of raw rehmannia root, lithospermum, peach kernels, radix stemonae, and camphor and the like, and the raw materials are prepared to obtain the external use medicinalpowder. The combination drug powder has the functions of clearing heat and dampness, dispelling wind and removing dandruff and relieving itching, and has good effect in preventing and treating rheumatic fever-type neurodermatitis. The combination drug powder is easy to use, and safe and effective.