The invention provides a ground vibration test fixture for a large-scale spacecraft. The ground vibration test fixture comprises a fixture main body, a first interface, a second interface, an upper end surface outer wall lug boss, a position limiting block and an upper end surface inner wall lug boss, wherein the first interface is arranged at the bottom of the fixture main body, the second interface is arranged at the top of the fixture main body, the upper end surface of the fixture main body is provided with the upper end surface outer wall lug boss and the upper end surface inner wall lug boss, and the position limiting block is arranged on the upper end surface outer wall lug boss and is used for limiting the transverse sliding of a limiting product. The ground vibration test fixture solves the problems of great weight, low intensity, low rigidity, low first-order base frequency and the like under the condition that an interface of an entity type large-scale vibration test fixture is enlarged. The fixture structure form adopts the rib plate type, the rigidity and the intensity of the large-scale vibration test fixture are greatly improved, the first-order frequency of the fixture is 3 to 5 times higher than that of an aircraft, and the safety and the reliability of the vibration test are greatly improved.