The invention relates to the field of test of mechanical properties of materials and in particular relates to a thermo-mechanical-environmental coupling effect testing device and application from room temperature to ultrahigh temperature. The device comprises an electronic universal testing machine, a loading control system, a power supply control system, an induction heater, a strain measurement system, a sample clamp, a temperature measuring system, a pressure control system, a display and analysis system and a vacuum system, wherein a vacuum cavity in the electronic universal testing machine is in a fully water-cooled design, and various functional windows, such as a sensor connector of the clamp and the electronic universal testing machine, an infrared or thermocouple temperature measuring opening of the temperature measuring system, a pressure control opening of the pressure control system, an induction power supply introduction opening of the power supply control system, an extensometer introduction opening of the strain measurement system and a connector of the vacuum system and the vacuum cavity, are reserved in different parts of the vacuum cavity. The device disclosed by the invention can quantitatively research the thermo-mechanical-environmental coupling effect and has the advantages of diversified tested mechanical property parameters, high sample heating and cooling speed and the like.