72 results about "Early disease" patented technology

New and improved applications of Raman Scattering are disclosed. These applications may be implemented with or without using an enhanced nano-structured surface that is trademarked as the RamanNanoChip™ disclosed in a pending patent. As a RamanNanoChip™ provides much higher sensitivity in SERS compared with conventional enhance surface, broader scopes of applications are now enabled and can be practically implemented as now disclosed in this application. Furthermore, a wide range of applications is achievable as new and improved Raman sensing applications. By applying the analysis of Raman scattering spectrum, applications can be carried out to identify unknown chemical compositions to perform the tasks of homeland security; food, drug and drinking materials safety; early disease diagnosis environmental monitoring; industrial process monitoring, precious metal and gem authentications, etc.

The present invention relates to the analysis and monitoring of ocular fluids for determining the physiological state of an organism, to monitor drug efficacy and dynamics, for early disease detection, as well as to certain molecular markers and fingerprints of identified molecules or molecule fragments in such analysis.

The invention discloses a kit for early screening of the lung cancer based on peripheral blood. The kit comprises a connector, a PCR primer and a capture probe. The connector comprises a Tag sequence,a Poly N sequence, a first hairpin sequence, a second hairpin sequence, a first index sequence, a first common primer combination sequence, a second common primer combination sequence and dUTP, and the first index sequence is used for distinguishing different peripheral blood samples; the PCR primer is a primer designed for 358 genes which are related to the pulmonary nodule and indirectly influence proliferation and differentiation of cells, and the PCR primer is used for being combined with the connector; the capture probe is a probe designed for the 358 genes which are related to the pulmonary nodule and indirectly influence proliferation and differentiation of the cells, and the capture probe is used for capturing a cfDNA area of plasma in the peripheral blood samples. The provided kit can be applied to early disease screening of the lung cancer, and the pulmonary nodule is diagnosed in a noninvasive and high-sensitivity mode.

Musculoskeletal fibroproliferative disorders, such as Dupuytren's disease may be treated by administering locally a TNF-α antagonist. TNF-α antagonists find particular utility in inhibiting the progression of early disease state Dupuytren's disease and other musculoskeletal fibroproliferative disorders and, in combination with extracellular matrix degradation agents (such ascollagenase or matrix metalloproteinase I), treating advanced disease state Dupuytren's disease and, in particular inhibiting recurrence.

The invention discloses a device and a method for detecting a blood vessel. The device comprises a visible light source, an optical fiber coupler, a lighting optical fiber, an imaging receiving channel, an infrared beam splitter, a far infrared lens zoom system, a far infrared detector, a visible light lens zoom system, a visible light image sensor and an image processing system. According to the characteristic and the blood vessel blood flow heat transfer property that different heat radiation is generated by metabolic activity of hot body cells, tissues or organs in different states, infrared thermal imaging technology is integrated with visible light imaging technology, a high-quality and high-contrast blood vessel image is acquired, analysis of related blood flow parameters such as blood vessel blood flow speed and blood perfusion can be assisted, and early disease prediction and health assessment are performed according to temperature characteristics of human tissues under different pathologies.

The invention belongs to the technical field of plant root-knot nematode inoculation methods, and particularly provides a plant root-knot nematode potting three-layer sick soil inoculation method. Themethod comprises the steps of 1, disease-free soil collection and treatment; 2, sick soil collection and treatment; 3, sick soil expanding propagation cultivation; 4, expanded propagation sick soil pretreatment; and 5, three-layer sick soil inoculation. The plant root-knot nematode potting three-layer sick soil inoculation method adopts a three-layer sick soil inoculation technology that disease-free soil is inoculated on upper and lower layers, and nematode sick soil is inoculated on a middle layer. Compared with an existing root-knot nematode egg and larvae inoculation technology, the technology approaches natural inoculation, the inoculation survival rate is high, a nematode selecting link is omitted, and the workload is greatly reduced. Compared with an existing root-knot nematode single sick soil inoculation technology, the technology has the advantages that the usage amount of the sick soil is reduced by 1 / 2-2 / 3, and the workload and cost of the collection, transportation, expanding propagation cultivation and the like of the sick soil are greatly reduced; and newly transplanted seedlings can be protected from being infected by nematodes, not only can the success of the inoculation be ensured, but also too early disease death of the seedlings can be avoided.

A system for predicting diseases may accumulate information about the volatile, semi-volatile, and non-volatile organic compounds in breath / saliva. Such information may be analyzed over time to identify early disease indications, using non-invasive data collection via breath and alert patients directly for follow-up with a health professional.