Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
31 results about "Domiphen bromide" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Domiphen bromide is a chemical antiseptic and a quaternary ammonium compound.
Hygiene mouthspray composition
The present invention relates to a mouthspray formulation, which reduces oral bacteria and is effective against dental plaque, gingivitis and oral malodor. The preferred formulation has a bactericidal agent with cetyl pyridinium chloride and domiphen bromide, an alcohol, a sweetener component, and a flavor system. The flavor system may also have or more of the following: a flavorant, a humectant, a surfactant, a sweetener, and a colorant agent.
Owner:LANDER INTANGIBLES
Whole Mouth Malador Control By A Combination Of Antibacterial And Deodorizing Agents
InactiveUS20110239736A1Effective controlCosmetic preparationsToilet preparationsTriclosanAmmonium compounds
Disclosed are oral care compositions effective to control mouth and breath malodour comprising in a pharmaceutically acceptable carrier, a combination of an antibacterial agent and a deodorizing or odor-neutralizing agent comprising a compound having the structurewherein R1, R2, R3, and R5 may be identical or different, each representing H, a linear or branched C1-C6 alkyl or alkenyl, phenyl, —OH or —ORa; R4 is —OH, —ORa, phenyl, or a linear or branched C1-C6 alkyl or alkenyl; and Ra is phenyl or a linear or branched C1-C6 alkyl or alkenyl. The odor-neutralizing agent may further comprise one or more of an additional odor-neutralizing compound selected from α-damascenone, α-isomethylionone, α-ionone, β-ionone, pulegone, piperitone, carvone, coenzyme Q10 or cinnamaldehyde.The antibacterial agent may comprise one or a mixture of a quaternary ammonium compound selected from cetylpyridinium chloride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride or domiphen bromide; metal ions such as stannous, zinc or copper; chlorhexidine; triclosan; triclosan monophosphate; or selected essential oils.
Owner:THE PROCTER & GAMBLE COMPANY
Mouth Rinse Emulsions
Disclosed are oral care mouth rinse compositions formulated as stable oil-in-water emulsions comprising:(a) at least about 0.025% by weight of a quaternary ammonium antimicrobial agent,(b) at least about 0.05% by weight of an essentially water-insoluble volatile oil, and(c) at least about 50% by weight water,wherein the emulsion comprises oil droplets having an average mean particle size of about 350 nm or less.Examples of quaternary ammonium antimicrobial agent include cetylpyridinium chloride (CPC), tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride or domiphen bromide.
Owner:THE PROCTER & GAMBLE COMPANY
Paint for reducing carburization of evaporative pattern steel castings
InactiveCN103071761AImprove high temperature breathabilityHigh refractorinessFoundry mouldsFoundry coresDomiphen bromideLost-foam casting
The invention discloses paint for evaporative pattern steel castings, which is characterized in that aggregates of the paint are ferrochromium mineral powder, brown corundum powder and bauxite; additives are limestone powder, ferric oxide powder and cryolite powder; binders are silicasol, aluminum sulfate and a VAE (vinyl acetate-ethylene) copolymer emulsion; suspension cross-linking agents are calcium bentonite, attapulgite and cellulose sodium carboxymethyl; and assistants are sodium carbonate, OP-10 polyethylene alkyl alcohol ether, an organic silicon defoamer and domiphen bromide. The paint has the characteristics that the appropriate refractory aggregates are selected to regulate the high temperature permeability of the paint and effectively eliminate carbon generated from pyrolysis of polystyrene foam; the additives are added to eliminate carbon generated from the pyrolysis of the polystyrene foam in a casting process of the steel castings and effectively inhibit a carburization defect of the evaporative pattern steel castings; and the appropriate binders and suspension cross-linking agents are added to realize the due room temperature strength and high temperature strength of a coating.
Owner:杨玉光
Deep-cleaning, antibacterial and tooth-protecting mouth wash based on chitosan derivatives and preparation method of mouth wash
InactiveCN106176546AWide range of raw materialsLow costCosmetic preparationsToilet preparationsOral diseasePropolis
The invention discloses a deep-cleaning, antibacterial and tooth-protecting mouth wash based on chitosan derivatives. The mouth wash is prepared from, by weight, 3% of chitosan derivatives, 5% of glycerol, 1.5% of xylitol, 2% of efficient solubilizer, 0.55% of citric acid, 0.3% of sodium citrate, 0.25% of malic acid, 0.12% of menthol, 0.15% of mint fragrance, 2% of propolis extracts, 3.5% of tea leaf extracts, 0.07% of caramel colour, 0.04% of saccharin sodium, 0.2% of chlorhexidine, 0.0003% of domiphen bromide and the balance deionized water. The invention provides the deep-cleaning, antibacterial and tooth-protecting mouth wash based on the chitosan derivatives and the preparation method of the mouth wash. The mouth wash prepared through the method has the functions of inhibiting bacteria, removing dental plaque and preventing oral ulcer, gingivitis and other oral diseases, and is good in antibacterial effect, quick in effect, free of toxic and side effects and comfortable in mouthfeel.
Owner:湖北立天生物工程有限公司
Contact lens with improved biocidal activity and related methods and materials
The present invention is directed to a contact lens comprising a porous lens material and a disinfectant, including but not limited to domiphen bromide. The disinfectant is typically absorbed into the pores of the lens. The present invention also includes a related process for manufacture, method of use and kit.
Owner:BAUSCH & LOMB INC
Reduction Of Tooth Staining Derived From Cationic Antimicrobials
Disclosed are oral care compositions having reduced tooth staining propensity and comprising in a pharmaceutically acceptable carrier, a cationic antimicrobial agent and an anti-stain agent comprising one or more materials from each of at least two of the following chemical groups:Group 1. anionic agents,Group 2. aldehydes, ketones, and other reactive carbonyl compounds andGroup 3. nonionic ethoxylated surfactants.Examples of cationic antimicrobial agent include quaternary ammonium compounds such as cetylpyridinium chloride, cetyl pyridinium fluoride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride and domiphen bromide; chlorhexidine; and metal ion sources to supply metal ions such as stannous, zinc or copper.
Owner:THE PROCTER & GAMBLE COMPANY
Lincomycin hydrochloride compound vaginal effervescent tablets and preparation method thereof
InactiveCN104906066ARelief the painRelieves symptoms of itchingPharmaceutical delivery mechanismAmine active ingredientsAdditive ingredientTopical treatment
The invention discloses lincomycin hydrochloride compound vaginal effervescent tablets and a preparation method thereof. The effervescent tablets comprise the following western medicine effective ingredients in parts by weight: 4-6 parts of lincomycin hydrochloride and 1-3 parts of domiphen bromide; and the effervescent tablets comprise the following raw medicinal materials of traditional Chinese medicine active ingredients in parts by weight: 20-25 parts of densefruit pittany root-bark, 22-27 parts of tuber fleeceflower root, 18-25 parts of Chinese waxgourd seed, 30-35 parts of argy wormwood leaf, 21-25 parts of herb of red-knees, 18-24 parts of plantain seed, 17-20 parts of villous amomum fruit, 25-28 parts of largehead atractylodes rhizome, 22-26 parts of Chinese angelica (stir-fried with wine), and 20-25 parts of medicinal auxiliary materials. The preparation method of the effervescent tablets comprises the steps of preparing materials, extracting active ingredients of the traditional Chinese medicines, performing granulation, and tabletting. The lincomycin hydrochloride compound vaginal effervescent tablets disclosed by the invention effectively overcome adverse reactions caused by oral administration of lincomycin hydrochloride, directly act on affected parts by adopting an external method for local treatment of vaginitis, take effect quickly, are good in curative effect, and are convenient to use.
Owner:QINGDAO HAIZHIXING BIOLOGICAL SCI & TECH
Natural sea salt nasal irrigation agent
InactiveCN106038588AFits the definitionThe formula is simple and rigorousSenses disorderPharmaceutical delivery mechanismBacteroidesGlycerol
Owner:长春呈实健康实业有限公司
Medical lubricating agent and preparation method thereof
InactiveCN104998304ASolve technical problems with high sensitization rateSurgeryCytotoxicityDomiphen bromide
The invention discloses a medical lubricating agent and a preparation method thereof, belongs to the technical field of medical instruments and medical treatment, and aims to solve the technical problem that the conventional medical instruments are high in allergic reaction rate when being used for diagnosis and treatment by entering natural orifices of human bodies. The medical lubricating agent is prepared from tamarind polysaccharide gum, glycerin, sodium hydroxide, dipotassium glycyrrhizinate, domiphen bromide and purified water; the preparation method comprises the following steps: adding tamarind polysaccharide gum, glycerin, dipotassium glycyrrhizinate and domiphen bromide into purified water, stirring until that the mixture is completely dissolved, and leaving to stand for 12 hours to obtain mixed liquor A; adding sodium hydroxide into purified water with the temperature being 30-45 DEG C, slowly adding the mixture into the mixed liquor A, and stirring for 0.5 hour; adding purified water for diluting, stirring until uniform mixing so as to obtain the medical lubricating agent. According to the medical lubricating agent and the preparation method thereof, provided by the invention, the cytotoxicity of the lubricating agent is lower than or equal to grade 2, mucous membrane irritant reaction is not caused, and sensitization is avoided; besides, a higher inhibition effect on enteric pathogenic bacteria, streptococcus pyogens and saccharomytes is achieved.
Owner:长春呈实健康实业有限公司
Mouth rinse emulsions
Disclosed are oral care mouth rinse compositions formulated as stable oil-in-water emulsions comprising: (a) at least about 0.025% by weight of a quaternary ammonium antimicrobial agent, (b) at least about 0.05% by weight of an essentially water-insoluble volatile oil, and (c) at least about 50% by weight water, wherein the emulsion comprises oil droplets having an average mean particle size of about 350 nm or less. Examples of quaternary ammonium antimicrobial agent include cetylpyridinium chloride (CPC), tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride or domiphen bromide.
Owner:THE PROCTER & GAMBLE COMPANY
Reduction of tooth staining derived from cationic antimicrobials
Owner:PROCTER & GAMBLE CO
Whole mouth malodor control by a combination of antibacterial and deodorizing agents
Owner:PROCTER & GAMBLE CO
Reduction of tooth staining derived from cationic antibacterials
Disclosed are oral care compositions having reduced tooth staining propensity and comprising in a pharmaceutically acceptable carrier, a cationic antimicrobial agent and an anti-stain agent comprising one or more materials from each of at least two of the following chemical groups:Group 1. anionic agents,Group 2. aldehydes, ketones, and other reactive carbonyl compounds andGroup 3. nonionic ethoxylated surfactants.Examples of cationic antimicrobial agent include quaternary ammonium compounds such as cetylpyridinium chloride, cetyl pyridinium fluoride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride and domiphen bromide; chlorhexidine; and metal ion sources to supply metal ions such as stannous, zinc or copper.
Owner:THE PROCTER & GAMBLE COMPANY
Novel cleaning agent for metal accessories
The invention discloses a novel cleaning agent for metal accessories. The cleaning agent comprises the following raw materials in parts by weight: 5.2-8.7 parts of nonylphenol ethoxylates, 2.5-5.3 parts of domiphen bromide, 2.7-7.3 parts of hexamethylenebis(nitrilodimethylene) tetraphosphonic acid, 5.2-8.3 parts of anionic surfactant, 4.2-5.3 parts of stearol, 5.1-6.3 parts of aminobenzene sulfonamide, 3.2-4.5 parts of secondary alkane sulphonates and 10-12 parts of water. The novel cleaning agent for metal accessories has strong infiltration capacity, can reach the bottom layer of a cleaned article to quickly dissolve and remove various dirt and impurities attached to surfaces of metal accessories, has no redeposition phenomena in cleaning, does not corrode or damage the surface of metals in the cleaning process, and is high in cleaning speed; after being cleaned with the cleaning agent, the surfaces of the metals are clean and bright, and good in quality, and the processing precision of metals can be effectively guaranteed.
Owner:QINGDAO HUIERTONG TRADING
Itching relieving lotion and preparation method thereof
ActiveCN1951445AGood insecticideImprove the bactericidal effectHydroxy compound active ingredientsDermatological disorderSlagCnidium
The invention discloses a lotion against itching, wherein each 1000ml of the lotion comprises flavescent sophora root 50-70g, yellow corktree bark 50-70g, Chinese prickly ash 15-25g, borneol 0.5-2g, cnidium fruit 25-35g, dittany bark 25-35g, menthol 0.5-2g, domiphen bromide 0.5-2g. The preparing process of the lotion comprises steps of immersing cnidium fruit and pricklyash peel with 20 times by weight of water, distilling and collecting volatile oil, charging 5ml of Tween-80, grinding into slag, gathering distilled aqueous solution, merging raw materials and charging 12 times by weight of water for immersion, grilling and filtering, charging 10 times by weight of water into drug dross, grilling twice, filtering the decoction liquid, merging the filter liquor, filtering and merging the filter liquor with distilled aqueous solution, obtaining extract through decompression and concentration, charging ethanol to content of 60%, homogenizing, stewing, extracting supernatant fluid, reclaiming ethanol till no alcohol smell is present, and diluting to 1000ml with water.
Owner:合肥华威药业有限公司
Screening model for lspd inhibitors and new application of ispd inhibitor dumiphene
ActiveCN102277411AHas anti-tuberculosis activityAntibacterial agentsMicrobiological testing/measurementMedicinePharmaceutical drug
The invention relates to a reagent set for screening a 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (IspD) inhibitor. The reagent set comprises methylerythritol phosphate (MEP), cytidine triphosphate (CTP), IspD, enzyme reaction buffer solution, an ion reagent and a reagent for determining pyrophosphoric acid (PPi). The invention also relates to a method for screening the IspD inhibitor. By the method, domiphen bromide with anti-tuberculosis activity is screened from more than 3,000 compounds. The invention also relates to application of the domiphen bromide to the in-vivo / in-vitro inhibition of Mycobacterium tuberculosis and the preparation of anti-tuberculosis medicines.
Owner:MEDICINE & BIOENG INST OF CHINESE ACAD OF MEDICAL SCI
Antibacterial contraceptive maintenance gel for women, and preparation method thereof
ActiveCN111012902AEasy to useDoes not affect sexual pleasurePeptide/protein ingredientsAerosol deliveryPhysiologyCervix
The invention discloses antibacterial contraceptive maintenance gel for women, and a preparation method thereof, and relates to the technical field of family planning. The preparation method comprisesthe following steps: adding a propylene glycol solution of domiphen bromide, an angelica polysaccharide solution, a propylene glycol solution of oat avenanthramides, a lysozyme solution and purifiedwater into a gelatinous refined okra glue solution while stirring, mixing, regulating the pH value to 5.0, and standing until swelling and mixing to obtain the antibacterial contraceptive maintenancegel for women. The preparation method is simple, and the antibacterial contraceptive maintenance gel is convenient to use, has a good maintenance effect on cervix uteri and vaginal mucosa, and is beneficial to long-term normal-temperature storage.
Owner:金方卓越(厦门)生物科技有限公司
External-use liquid medicine for treating gynecological inflammation
InactiveCN109529030AFast absorptionPlay a repairAntibacterial agentsPharmaceutical delivery mechanismAntigenHippophae rhamnoides fruit
The invention relates to an external-use liquid medicine for treating gynecological inflammation. The external-use liquid medicine comprises the following raw materials of a radix sophorae flavescentis extract, a cortex phellodendri extract, a dandelion extract, a radix angelica sinensis extract, hippophae rhamnoides fruit flavone, a rose flower extract, egg white staphylococcus aureus enterotoxin, probiotics and domiphen bromide. The external-use liquid medicine disclosed by the invention is superhigh in effects of diminishing inflammation and killing bacteria; besides, through added super antigens, immunity can be rapidly regulated or activated by 2000-50000 times, body scent can be increased, hormone level can be balanced, the external-use liquid medicine can be quickly absorbed by skinand mucosa tissue, and the external-use liquid medicine can have the effects of repairing and treating on organs around the vagina.
Owner:宋永红
High-efficiency biological preservative for cosmetics
InactiveCN108542795AImprove anti-corrosion performanceNo side effectsCosmetic preparationsToilet preparationsSide effectPreservative
The invention discloses a high-efficiency biological preservative for cosmetics. The high-efficiency biological preservative for the cosmetics is prepared from the following raw materials in parts byweight: 2 to 3 parts of natamycin; 6 to 8 parts of domiphen bromide; 2 to 5 parts of thymol crystals; 10 to 16 parts of citric acid; and 3 to 9 parts of maltodextrin. The high-efficiency biological preservative for the cosmetics has good antiseptic effect, no irritating, no toxic and side effects, has the characteristics of biodegradability and the like, is non-toxic, harmless, green and environmentally friendly, and is suitable for widespread promotion and application.
Owner:TAICANG ROODEE BIOTECH RES INST
Vaginitis lotion preparation method
ActiveCN100581567CGood insecticideImprove the bactericidal effectHydroxy compound active ingredientsDermatological disorderSlagCnidium
Owner:合肥华威药业有限公司
Paint for reducing carburization of evaporative pattern steel castings
InactiveCN103071761BImprove high temperature breathabilityHigh refractorinessFoundry mouldsFoundry coresSodium BentoniteDomiphen bromide
The invention discloses paint for evaporative pattern steel castings, which is characterized in that aggregates of the paint are ferrochromium mineral powder, brown corundum powder and bauxite; additives are limestone powder, ferric oxide powder and cryolite powder; binders are silicasol, aluminum sulfate and a VAE (vinyl acetate-ethylene) copolymer emulsion; suspension cross-linking agents are calcium bentonite, attapulgite and cellulose sodium carboxymethyl; and assistants are sodium carbonate, OP-10 polyethylene alkyl alcohol ether, an organic silicon defoamer and domiphen bromide. The paint has the characteristics that the appropriate refractory aggregates are selected to regulate the high temperature permeability of the paint and effectively eliminate carbon generated from pyrolysis of polystyrene foam; the additives are added to eliminate carbon generated from the pyrolysis of the polystyrene foam in a casting process of the steel castings and effectively inhibit a carburization defect of the evaporative pattern steel castings; and the appropriate binders and suspension cross-linking agents are added to realize the due room temperature strength and high temperature strength of a coating.
Owner:杨玉光
Liquid dressing
InactiveCN100423785CImprove the bactericidal effectAvoid bandagingAbsorbent padsBandagesMedicineDomiphen bromide
The present invention relates to a liquid dressing. It is characterized by that its composition includes (by wt%) 0.1-0.5% of chitin, 0.02-0.06% of domiphen bromide and 0.5-1.5% of collagen protein. The chitin and collagen protein can be used for quickly forming a layer of membrane, so that it has the effect of quickly-killing bacterial, disinfection, arresting bleeding, stopping pain and repairing surface of wound, etc.
Owner:黑龙江燎原科技有限公司
Sodium azulene sulfonate compound mouthwash and preparation method thereof
ActiveCN112402278AImprove performanceLong validity periodCosmetic preparationsToilet preparationsSulfonateMouthwash Product
The invention discloses sodium azulene sulfonate compound mouthwash. The sodium azulene sulfonate compound mouthwash is prepared from the following raw materials in percentage by mass: 0.03 to 3 percent of an antibacterial agent, 0.003 to 0.3 percent of sodium azulene sulfonate, 0.36 to 9 percent of a solubilizer, 0.008 to 15 percent of a sweetener, 0.005 to 2 percent of a cooling agent, 0.005 to0.3 percent of cetylpyridinium chloride, 0.03 to 3 percent of a preservative, 0 to 5 percent of ethanol, 0 to 0.1 percent of a pH (potential of Hydrogen) regulator and the balance de-ionized water, wherein the antibacterial agent is domiphen bromide or chlorhexidine gluconate. The invention further discloses a preparation method of the sodium azulene sulfonate compound mouthwash. The sodium azulene sulfonate compound mouthwash provided by the invention has high product stability and long effective period.
Owner:北京华素制药股份有限公司 +1
A compound tincture for treating eczema
InactiveCN104474052BAlleviate inflammatory painPharmaceutical delivery mechanismAmine active ingredientsMonkshoodsIndometacin
The invention discloses a compound tincture for treating eczema. The compound tincture comprises a western medicine, a traditional Chinese medicine and a solvent, wherein the western medicine comprises the following active ingredients in parts by weight: 15-20 parts of indometacin and 0.5-1 part of domiphen bromide; the traditional Chinese medicine comprises the following active ingredients in parts by weight: 150-200 parts of lithospermum, 80-100 parts of honeysuckle, 120-150 parts of tuberculate speranskia herb, 80-100 parts of mulberry twig, 180-200 parts of monkshood, 70-90 parts of rhizoma atractylodis and 120-150 parts of radix clematidis; and the solvent is 1000 parts of alcohol at a mass concentration of 60-70%.The compound tincture is prepared by preparing materials, extracting the active ingredients of raw traditional Chinese medicines, and dissolving the active ingredients of the western medicine. The active ingredients and the solvent have a synergistic effect, and the compound tincture effectively clears away heat, carries out detoxification, sterilization and anti-inflammation, can relieve itching and pain in a short period, effectively cures the eczema, has no toxic or side effects, and is safe to administrate and simple to prepare.
Owner:李秀英
Medicine composition for treating sphagitis, amygdalitis, thrush and ulcerative stomatitis
The invention discloses a medicine composition for treating sphagitis, amygdalitis, thrush and ulcerative stomatitis. The medicine composition is characterized by comprising the following ingredients in parts by weight: 1-200 parts of domiphen bromide, 1-200 parts of mischobulbum element, 1-200 parts of powdered sugar, 1-200 parts of dextrin, 1-100 parts of lemon yellow, 1-50 parts of flavoring orange essence, 1-200 parts of 15% dextrin pulp, 1-50% of 95% alcohol and 1-50 parts of magnesium stearate. The medicine composition for treating the sphagitis, the amygdalitis, the thrush and the ulcerative stomatitis is convenient to carry and take, can be effectively absorbed by a mouth mucosa via sublingual administration, is good in taste and can be pleasantly accepted by adults and children.
Owner:KAMP PHARMA
Whole mouth malador control by a combination of antibacterial and deodorizing agents
PendingUS20220257484A1Effective controlCosmetic preparationsToilet preparationsTriclosanAmmonium compounds
Owner:PROCTER & GAMBLE CO
Compound tincture for treating eczema
InactiveCN104474052AAlleviate inflammatory painPharmaceutical delivery mechanismAmine active ingredientsIndometacinMonkshoods
The invention discloses a compound tincture for treating eczema. The compound tincture comprises a western medicine, a traditional Chinese medicine and a solvent, wherein the western medicine comprises the following active ingredients in parts by weight: 15-20 parts of indometacin and 0.5-1 part of domiphen bromide; the traditional Chinese medicine comprises the following active ingredients in parts by weight: 150-200 parts of lithospermum, 80-100 parts of honeysuckle, 120-150 parts of tuberculate speranskia herb, 80-100 parts of mulberry twig, 180-200 parts of monkshood, 70-90 parts of rhizoma atractylodis and 120-150 parts of radix clematidis; and the solvent is 1000 parts of alcohol at a mass concentration of 60-70%.The compound tincture is prepared by preparing materials, extracting the active ingredients of raw traditional Chinese medicines, and dissolving the active ingredients of the western medicine. The active ingredients and the solvent have a synergistic effect, and the compound tincture effectively clears away heat, carries out detoxification, sterilization and anti-inflammation, can relieve itching and pain in a short period, effectively cures the eczema, has no toxic or side effects, and is safe to administrate and simple to prepare.
Owner:李秀英
Model for screening 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (IspD) inhibitor and novel application of IspD inhibitor domiphen bromide
ActiveCN102277411BHas anti-tuberculosis activityAntibacterial agentsMicrobiological testing/measurementPhosphateAntituberculous drugs
The invention relates to a reagent set for screening a 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (IspD) inhibitor. The reagent set comprises methylerythritol phosphate (MEP), cytidine triphosphate (CTP), IspD, enzyme reaction buffer solution, an ion reagent and a reagent for determining pyrophosphoric acid (PPi). The invention also relates to a method for screening the IspD inhibitor. By the method, domiphen bromide with anti-tuberculosis activity is screened from more than 3,000 compounds. The invention also relates to application of the domiphen bromide to the in-vivo / in-vitro inhibition of Mycobacterium tuberculosis and the preparation of anti-tuberculosis medicines.
Owner:MEDICINE & BIOENG INST OF CHINESE ACAD OF MEDICAL SCI
Clean-free skin and hand micro-emulsion disinfectant agent and preparation method thereof
ActiveCN103230386BImprove securityImprove stabilityAntibacterial agentsAmine active ingredientsEmulsionChlorhexidine Acetate
The invention relates to clean-free skin and hand micro-emulsion disinfectant agent, and in particular relates to a clean-free skin and hand micro-emulsion disinfectant agent and a preparation method thereof. Under the situation of guaranteeing the effective sterilization, the concentration of ethanol is controlled to be less than 30 percent. Active sterilizing components of the disinfectant agent are chlorhexidine acetate and domiphen bromide, wherein the domiphen bromide has a surface active effect, the ethanol is used as an auxiliary surfactant and a propellant, and a skin and hand micro-emulsion disinfectant solution with the granularity of 1 to 200nm is prepared from injection oil, the surfactant and natural moistening skincare components. The skin and hand micro-emulsion disinfectant solution is practical, simple, high in safety, good in stability and low in thrilling, nano-grade particles form a protection film on a disinfected part, the sterilizing efficacy is high, the added natural moistening skincare component can deeply moisten and whiten the skin, the symptoms such as dry and dry itching caused by utilizing the disinfectant solution with high ethanol content for a long time can be remarkably improved, and an effect for protecting the skin and the hands can be realized.
Owner:XUZHOU MEDICAL COLLEGE
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com