Lincomycin hydrochloride compound vaginal effervescent tablets and preparation method thereof

Abstract

The invention discloses lincomycin hydrochloride compound vaginal effervescent tablets and a preparation method thereof. The effervescent tablets comprise the following western medicine effective ingredients in parts by weight: 4-6 parts of lincomycin hydrochloride and 1-3 parts of domiphen bromide; and the effervescent tablets comprise the following raw medicinal materials of traditional Chinese medicine active ingredients in parts by weight: 20-25 parts of densefruit pittany root-bark, 22-27 parts of tuber fleeceflower root, 18-25 parts of Chinese waxgourd seed, 30-35 parts of argy wormwood leaf, 21-25 parts of herb of red-knees, 18-24 parts of plantain seed, 17-20 parts of villous amomum fruit, 25-28 parts of largehead atractylodes rhizome, 22-26 parts of Chinese angelica (stir-fried with wine), and 20-25 parts of medicinal auxiliary materials. The preparation method of the effervescent tablets comprises the steps of preparing materials, extracting active ingredients of the traditional Chinese medicines, performing granulation, and tabletting. The lincomycin hydrochloride compound vaginal effervescent tablets disclosed by the invention effectively overcome adverse reactions caused by oral administration of lincomycin hydrochloride, directly act on affected parts by adopting an external method for local treatment of vaginitis, take effect quickly, are good in curative effect, and are convenient to use.

Description

technical field [0001] The invention relates to a vaginal effervescent tablet, in particular to a lincomycin hydrochloride compound vaginal effervescent tablet and a preparation method thereof. Background technique [0002] Vaginitis is the most common infectious disease in women. Its common symptoms are increased vaginal discharge, genital itching and burning pain, which may be accompanied by frequent urination, dysuria and dyspareunia. Gynecological examination showed increased vaginal discharge, vaginal mucosa hyperemia or scattered bleeding spots, a large amount of leucorrhea in the posterior fornix of the vagina, gray-yellow or yellow-green purulent discharge, sometimes foamy or white thick curd or bean dregs. Edema, scratches, and geographic erythema were seen on the vulva. [0003] Vaginal mucosal administration has a history of nearly a hundred years, and it has many advantages compared with traditional oral administration. It can be used not only locally, but also ...

AI Technical Summary

Problems solved by technology

[0006] In order to overcome the adverse reactions of oral or injectable lincomycin hydrochloride, and to make up for the defect that lincomycin hydrochloride does not currently have topical drug administration for human vaginal mucosa, the invention provides a Chinese-Western mixture of lincomycin hydrochloride Compound Vaginal Effervescent Tablets

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