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Deep-cleaning, antibacterial and tooth-protecting mouth wash based on chitosan derivatives and preparation method of mouth wash

A technology of chitosan derivatives and mouthwash, which is applied in the field of oral care, can solve problems such as difficulty in popularization and application, harm to oral health, and poor use effect, and achieve the effect of improving oral immunity, no toxic side effects, and low cost

Inactive Publication Date: 2016-12-07
湖北立天生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing traditional mouthwash on the market has a pH value of around 7 and contains alcohol (ethanol). If alcohol stays in the mouth for a long time, the alcohol will turn into acetaldehyde, which is harmful to oral health. The effect is poor and the taste is not good. Patients are difficult to accept and other reasons, making it difficult to popularize and apply

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 2%, glycerin 5%, xylitol 1%, high-efficiency solubilizer 1.5% , citric acid 0.5%, sodium citrate 0.1%, malic acid 0.1%, menthol 0.1%, mint flavor 0.1%, propolis extract 1%, tea extract 2%, caramel color 0.01%, saccharin sodium 0.01%, washing Bitai 0.1%, Domifene 0.0001%, and deionized water as the balance.

[0028] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0029] Further, the high-efficiency solubilizer is C0-40.

[0030] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0031] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0032] (2) Heat deionized water to 90°C and...

Embodiment 2

[0040]Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 3%, glycerin 5%, xylitol 1.5%, high-efficiency solubilizer 2% , citric acid 0.55%, sodium citrate 0.3%, malic acid 0.25%, menthol 0.12%, mint flavor 0.15%, propolis extract 2%, tea extract 3.5%, caramel color 0.07%, saccharin sodium 0.04%, washing Bitai 0.2%, Domifene 0.0003%, and deionized water as the balance.

[0041] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0042] Further, the high-efficiency solubilizer is C0-40.

[0043] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0044] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0045] (2) Heat the deionized water to...

Embodiment 3

[0053] Based on chitosan derivatives deep cleaning, antibacterial mouthwash, made of the following raw materials in weight ratio: chitosan derivatives 5%, glycerin 6%, xylitol 3%, high-efficiency solubilizer 3% , citric acid 1%, sodium citrate 0.5%, malic acid 0.3%, menthol 0.2%, mint flavor 0.2%, propolis extract 3%, tea extract 4%, caramel color 0.1%, saccharin sodium 0.05%, washing Bitai 0.3%, Domiphene 0.0003%, and deionized water as the balance.

[0054] Further, the chitosan derivatives are chitosan, chitooligosaccharide and carboxymethyl chitosan.

[0055] Further, the high-efficiency solubilizer is C0-40.

[0056] Based on the preparation method of chitosan derivative deep cleaning and antibacterial mouthwash, the preparation method comprises the following steps:

[0057] (1) Weighing: Inspect various raw materials according to the requirements, and weigh them according to the proportion of the formula for later use;

[0058] (2) Heat the deionized water to 90°C and...

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Abstract

The invention discloses a deep-cleaning, antibacterial and tooth-protecting mouth wash based on chitosan derivatives. The mouth wash is prepared from, by weight, 3% of chitosan derivatives, 5% of glycerol, 1.5% of xylitol, 2% of efficient solubilizer, 0.55% of citric acid, 0.3% of sodium citrate, 0.25% of malic acid, 0.12% of menthol, 0.15% of mint fragrance, 2% of propolis extracts, 3.5% of tea leaf extracts, 0.07% of caramel colour, 0.04% of saccharin sodium, 0.2% of chlorhexidine, 0.0003% of domiphen bromide and the balance deionized water. The invention provides the deep-cleaning, antibacterial and tooth-protecting mouth wash based on the chitosan derivatives and the preparation method of the mouth wash. The mouth wash prepared through the method has the functions of inhibiting bacteria, removing dental plaque and preventing oral ulcer, gingivitis and other oral diseases, and is good in antibacterial effect, quick in effect, free of toxic and side effects and comfortable in mouthfeel.

Description

technical field [0001] The invention relates to the technical field of oral care, in particular to a mouthwash based on chitosan derivatives for deep cleaning and antibacterial tooth protection and a preparation method thereof. Background technique [0002] With the development of economy and society and the improvement of people's living standards, people's dietary structure is also changing, and corresponding oral diseases are becoming more and more common. At present, the incidence of oral diseases is extremely high, and the prevention and treatment of oral diseases And tooth protection is particularly important. The pathological phenomenon of the oral cavity in the event of damage by external physical and chemical factors, invasion of pathogens, abnormal dental and maxillofacial development, and systemic diseases. There are many types of oral diseases, which originate in the oral cavity. Oral inflammatory diseases, such as oral ulcers, pharyngitis, laryngitis, tonsilli...

Claims

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Application Information

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IPC IPC(8): A61K8/98A61K8/97A61K8/73A61K8/365A61K8/43A61K8/41A61K8/362A61K8/34A61Q11/00A61P1/02
CPCA61K8/34A61K8/345A61K8/362A61K8/365A61K8/416A61K8/43A61K8/736A61K8/97A61K8/988A61Q11/00
Inventor 刘小辉
Owner 湖北立天生物工程有限公司
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