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Itching relieving lotion and preparation method thereof

A technology of lotion and filtrate, which is applied in the field of drugs for the treatment of common gynecological diseases, can solve problems such as ineffective antipruritic effect, pollution of underwear, verrucous hyperplasia, etc., achieve good insecticidal and bactericidal effects, good curative effect, and small adverse reactions Effect

Active Publication Date: 2007-04-25
合肥华威药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These medicines are commonly used, but the antipruritic effect is not obvious, and some can also cause verrucous hyperplasia. Because the medicine liquid is dark in color, it will also pollute the underwear

Method used

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  • Itching relieving lotion and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

no. 1 example

[0028] Take the following prescription:

[0029] Sophora flavescens 50g, cork 50g, Chinese prickly ash 15g, borneol 0.5g, cranberry seed 25g, white fresh skin 25g, menthol 0.5g, domiphene 0.5g.

[0030] Prepare Keyangshu lotion according to the prescription of the above components through the following steps:

[0031] 1) Soak 25g of Cnidium monnieri and 15g of Zanthoxylum bungeanum with 20 times its weight in water for 1 hour, then distill for 5 hours and collect the volatile oil, add 5ml Tween-80 to grind into medicine residue, and collect the distilled aqueous solution separately;

[0032] 2) Combine the medicinal dregs with 50g of Sophora flavescens, 50g of cork and 25g of white fresh peel, put them in a multifunctional extraction tank, add 12 times the weight of water to soak for 1 hour, then decoct for 1 hour, then use 100 for the decoction Mesh screen filtration;

[0033] 3) Add 10 times the weight of the medicinal residues in step 2) to decoction twice for 1 hour each time....

no. 2 example

[0038] Take the following prescription:

[0039] Sophora flavescens 70g, Phellodendron 70g, Sichuan pepper 25g, Borneol 2g, Cnidium 35g, White fresh skin 35g, Menthol 2g, Dumiphene 2g.

[0040] Prepare Keyangshu lotion according to the prescription of the above components through the following steps:

[0041] 1) Soak 35g of Cnidium monnieri and 25g of Zanthoxylum bungeanum with 20 times its weight in water for 1 hour, then distill for 5 hours and collect the volatile oil, add 5ml Tween-80 to grind into medicine residue, and collect the distilled aqueous solution separately;

[0042] 2) Combine the medicinal dregs with 70g of Sophora flavescens, 70g of cork and 35g of white fresh peel, put them in a multifunctional extraction tank, add 12 times the weight of water to soak for 1 hour, then decoct for 1 hour, then use 100 Mesh screen filtration;

[0043] 3) Add 10 times the weight of the medicinal residues in step 2) to decoction twice for 1 hour each time. After filtering the decoct...

no. 3 example

[0048] Preferably, the following prescriptions are taken:

[0049] Sophora flavescens 60g, cork 60g, Chinese pepper 20g, borneol 1g, Cnidium cnidium 30g, white fresh skin 30g, menthol 1g, and domiphene 1g.

[0050] Prepare Keyangshu lotion according to the prescription of the above components through the following steps:

[0051] 1) Soak 30g of Cnidium and 20g of Zanthoxylum bungeanum with 20 times its weight in water for 1 hour, and then distill for 5 hours to collect the volatile oil, add 5ml of Tween-80 to grind into medicine residue, and collect the distilled aqueous solution separately;

[0052] 2) Combine the medicinal dregs with 60g of Sophora flavescens, 60g of cork and 30g of white fresh peel, put them in a multifunctional extraction tank, add 12 times the weight of water to soak for 1 hour, then decoct for 1 hour, then use 100 meshes for the decoction Screen filter

[0053] 3) Add 10 times the weight of the medicinal residues in step 2) to decoction twice for 1 hour each...

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Abstract

The invention discloses a lotion against itching, wherein each 1000ml of the lotion comprises flavescent sophora root 50-70g, yellow corktree bark 50-70g, Chinese prickly ash 15-25g, borneol 0.5-2g, cnidium fruit 25-35g, dittany bark 25-35g, menthol 0.5-2g, domiphen bromide 0.5-2g. The preparing process of the lotion comprises steps of immersing cnidium fruit and pricklyash peel with 20 times by weight of water, distilling and collecting volatile oil, charging 5ml of Tween-80, grinding into slag, gathering distilled aqueous solution, merging raw materials and charging 12 times by weight of water for immersion, grilling and filtering, charging 10 times by weight of water into drug dross, grilling twice, filtering the decoction liquid, merging the filter liquor, filtering and merging the filter liquor with distilled aqueous solution, obtaining extract through decompression and concentration, charging ethanol to content of 60%, homogenizing, stewing, extracting supernatant fluid, reclaiming ethanol till no alcohol smell is present, and diluting to 1000ml with water.

Description

Technical field [0001] The invention relates to a medicine for treating common gynecological diseases-Keyangshu lotion and a preparation method thereof, belonging to the field of traditional Chinese medicine. Background technique [0002] Common gynecological diseases include vaginitis and genital itching. In recent years, due to the influence of many factors, the disease has a tendency to occur frequently in clinic, which seriously endangers the physical and mental health of women and affects their life, work and study. [0003] Although the treatment of western medicine takes effect quickly, long-term use is more irritating to the vaginal mucosa, which is not easy for most women to accept, and often fails to persist after using it for a period of time, causing the drug to fail to achieve the expected curative effect. After oral administration of chemicals, the concentration of the drugs reaching the vagina is lower. A larger oral dose is needed to kill bacteria and trichomonias...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61P15/02A61P17/04A61K31/045A61K31/138
Inventor 李贵华
Owner 合肥华威药业有限公司
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