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Medical lubricating agent and preparation method thereof

A technology of lubricant and purified water, applied in the field of medical treatment and medical equipment, which can solve the problem of high sensitization rate

Inactive Publication Date: 2015-10-28
长春呈实健康实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention aims to solve the technical problem of high sensitization rate existing in the diagnosis and treatment of existing medical devices entering the natural cavity of the human body, and provides a medical lubricant and a preparation method thereof

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0017] Specific embodiment one: the Chinese medicine lubricant of this embodiment is made of the following raw materials in terms of mass percentage: 0.5% of tamarind polysaccharide gum, 20% of glycerin, 1.0% of sodium hydroxide, 0.5% of dipotassium glycyrrhizinate, rice Fen 1.0%, and the balance is purified water; its preparation method: add tamarind polysaccharide gum, glycerin, dipotassium glycyrrhizinate and domiphene to the purified water accounting for 20% of the total mass of purified water, stir until completely dissolved, and let stand for 12 hours, to obtain the mixed solution A; sodium hydroxide was added to the purified water whose temperature was 30°C and the consumption accounted for 0.2% of the total mass of the purified water, then slowly added to the mixed solution A, and stirred for 0.5h; Stir until the mixture is uniform; the medical lubricant is obtained; all the above operations are carried out at a room temperature of 25°C, a relative humidity of 50%, and ...

specific Embodiment approach 2

[0019] Specific embodiment two: the Chinese medicine lubricant of this embodiment is made of the following raw materials in terms of mass percentage: carbomer 0.5%, simethicone 40%, sodium hydroxide 0.5%, dipotassium glycyrrhizinate 1.0%, Methyl benzoate 2.0%, surplus is purified water; Its preparation method is to carry out according to the following steps: add carbomer, dimethicone, dipotassium glycyrrhizinate and methyl benzoate to account for 35% of the total mass of purified water % of purified water, stirred until completely dissolved, and stood still for 12 hours to obtain mixed solution A; add sodium hydroxide to purified water with a temperature of 45°C and an amount accounting for 0.2% of the total mass of purified water, and then slowly add it to mixed solution A , stirred for 0.5h; add purified water to make up the volume, and then stir until mixed evenly; the medical lubricant is obtained; all the above operations are carried out under the conditions of room temper...

specific Embodiment approach 3

[0022] Specific embodiment three: In this embodiment, the Chinese medicine lubricant is made of the following raw materials in terms of mass percentage: 0.6% gelatin, 40% glycerin replaced by water-based silicone oil, 2% sodium hydroxide, and 0.1% to 1.0% dipotassium glycyrrhizinate , benzalkonium bromide 5%, and the balance is deionized water; its preparation method is carried out according to the following steps: gelatin, water-based silicone oil are replaced glycerin, dipotassium glycyrrhizinate and benzalkonium bromide are added to account for 10% of the total mass of purified water % of purified water, stirred until completely dissolved, and stood still for 12 hours to obtain mixed solution A; add sodium hydroxide to purified water with a temperature of 30°C and an amount of 0.1% of the total mass of purified water, and then slowly add it to mixed solution A , stirred for 0.5h; add purified water to make up the volume, and then stir until mixed evenly; the medical lubrican...

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Abstract

The invention discloses a medical lubricating agent and a preparation method thereof, belongs to the technical field of medical instruments and medical treatment, and aims to solve the technical problem that the conventional medical instruments are high in allergic reaction rate when being used for diagnosis and treatment by entering natural orifices of human bodies. The medical lubricating agent is prepared from tamarind polysaccharide gum, glycerin, sodium hydroxide, dipotassium glycyrrhizinate, domiphen bromide and purified water; the preparation method comprises the following steps: adding tamarind polysaccharide gum, glycerin, dipotassium glycyrrhizinate and domiphen bromide into purified water, stirring until that the mixture is completely dissolved, and leaving to stand for 12 hours to obtain mixed liquor A; adding sodium hydroxide into purified water with the temperature being 30-45 DEG C, slowly adding the mixture into the mixed liquor A, and stirring for 0.5 hour; adding purified water for diluting, stirring until uniform mixing so as to obtain the medical lubricating agent. According to the medical lubricating agent and the preparation method thereof, provided by the invention, the cytotoxicity of the lubricating agent is lower than or equal to grade 2, mucous membrane irritant reaction is not caused, and sensitization is avoided; besides, a higher inhibition effect on enteric pathogenic bacteria, streptococcus pyogens and saccharomytes is achieved.

Description

technical field [0001] The invention belongs to the field of medical equipment and medical technology; in particular, it relates to a medical lubricant and a preparation method thereof. Background technique [0002] When medical devices in medical institutions enter the natural cavity of the human body for diagnosis and treatment, due to the nervousness of patients and individual differences, the cavity will usually be dry and dry, which will cause the medical device to block and the sliding effect will not be good. Glycerin, dimethyl silicone oil and water-based silicone oil have been used as medical lubricants for a long time. The disadvantages of the above-mentioned lubricant products are that the sensitization rate is as high as 10% or even higher, and the safety, effectiveness, microbial indicators, antibacterial rate or Killing rate and so on have not been evaluated so far. So much so that the endoscopy departments of major medical institutions have posted "Instructio...

Claims

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Application Information

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IPC IPC(8): A61L31/04A61L31/16A61L31/14
Inventor 佟乐佟为佟黎明
Owner 长春呈实健康实业有限公司
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