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Antibacterial contraceptive maintenance gel for women, and preparation method thereof

A gel and lysozyme technology, applied in biochemical equipment and methods, local antibacterial agents, medical preparations of non-active ingredients, etc., can solve problems such as health hazards and secondary infections

Active Publication Date: 2020-04-17
金方卓越(厦门)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition to factors such as hygiene habits and hygiene conditions, such a high rate of inventions is mainly caused by the secondary infection caused by the widespread use of nonoxynol-containing contraceptives, which has already brought great harm to the health of the people. The general health development strategy advocated by the state to improve the national health level does not match

Method used

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  • Antibacterial contraceptive maintenance gel for women, and preparation method thereof
  • Antibacterial contraceptive maintenance gel for women, and preparation method thereof
  • Antibacterial contraceptive maintenance gel for women, and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0077] 1.2 Preparation of experimental liquid:

[0078] Take 0.25 g of lysozyme and dissolve it in 99.75 mL of purified water to make a 0.25% lysozyme solution for later use, with a pH value of 5.5.

[0079] 1.3 Semen samples:

[0080] The semen samples of 20 cases in this group were collected from paid volunteers. The 20 cases of semen collection were 23-35 years old, abstained from sexual intercourse for 3-7 days, and collected semen by masturbation. The collected semen was kept in a constant temperature water tank at 30°C, and routine inspection was performed after liquefaction. Semen selection criteria: semen volume 2-5mL, semen liquefaction time 30min, pH value 7.2-7.5, sperm count ≥60x10 6 / ml, sperm motility rate > 70%, sperm deformity rate < 25%, of which 18 cases were qualified as semen samples.

[0081] 1.4 Experimental method:

[0082] According to the Sander-Cramer method and standard of in vitro spermicide test recommended by the World Health Organization (WH...

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Abstract

The invention discloses antibacterial contraceptive maintenance gel for women, and a preparation method thereof, and relates to the technical field of family planning. The preparation method comprisesthe following steps: adding a propylene glycol solution of domiphen bromide, an angelica polysaccharide solution, a propylene glycol solution of oat avenanthramides, a lysozyme solution and purifiedwater into a gelatinous refined okra glue solution while stirring, mixing, regulating the pH value to 5.0, and standing until swelling and mixing to obtain the antibacterial contraceptive maintenancegel for women. The preparation method is simple, and the antibacterial contraceptive maintenance gel is convenient to use, has a good maintenance effect on cervix uteri and vaginal mucosa, and is beneficial to long-term normal-temperature storage.

Description

technical field [0001] The invention relates to the field of family planning, in particular to a novel antibacterial and contraceptive maintenance gel used by women. Background technique [0002] Contraception and family planning are an eternal theme of protecting women's reproductive health. Work on how to prevent unwanted pregnancy, avoid induced abortion, and protect women's reproductive health still needs to be continued. Among many contraceptive measures, the method of vaginal inactivation of sperm to control conception is still the easiest and most reliable method of contraception. In vitro spermicide, such as vaginal contraceptive film and contraceptive gel, is the most common means of birth control and contraception. [0003] Both vaginal contraceptive films and contraceptive gels contain nonoxynol (Nonoxinol-9, N9), a spermicidal surfactant. Nonoxynol-9 (Nonoxinol-9, N9) has been used as a spermicide in the United States and some other countries for more than 30 y...

Claims

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Application Information

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IPC IPC(8): A61K38/47A61K9/06A61K31/14A61K31/196A61K31/715A61K47/36A61P15/02A61P15/18A61P31/02
CPCA61K38/47A61K31/14A61K31/715A61K31/196A61K47/36C12Y302/01017A61K9/0034A61K9/06A61P15/18A61P15/02A61P31/02A61K2300/00Y02A50/30
Inventor 罗宇明
Owner 金方卓越(厦门)生物科技有限公司
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