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Medicine composition for treating sphagitis, amygdalitis, thrush and ulcerative stomatitis

A technology for tonsillitis and a composition is applied to the pharmaceutical composition of thrush and ulcerative stomatitis, tonsillitis, and the field of treating pharyngitis, can solve problems such as poor drug tolerance, no clinical verification, influence on life, etc., and achieves convenience The effect of taking, pleasant acceptance, and easy portability

Inactive Publication Date: 2017-06-13
KAMP PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term use of these drugs can lead to environmental disturbances in the oral cavity
Surgical methods for tonsillitis are expensive, and it is not easy to evaluate whether the immune function has declined
Ulcerative stomatitis is directly coated with powder on the affected area, which has poor drug tolerance and affects life
The patented Chinese medicine prescription is just a simple patchwork of many single herbs, without a certain amount of clinical verification, and without the support of TCM theory, its clinical efficacy is yet to be evaluated

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] a) Prescription

[0023] Main ingredient: Domiphene 0.5g.

[0024] Excipients: 0.4g vanillin, 400g powdered sugar, 40g dextrin, 0.125g tartrazine, 0.4ml orange flavor, 0.3-0.32g dextrin slurry 15%, 7g 95% ethanol, 3g magnesium stearate, made 1000 pieces.

[0025] 2) Preparation method:

[0026] 1. Weigh domiphene and vanillin according to the prescription, put them in a 1000ml measuring cup, add 95% ethanol to dissolve them, mix well with powdered sugar and dextrin, and pass through 60-mesh and 80-mesh sieves once respectively. Mix well and set aside.

[0027] 2. After dissolving lemon yellow with hot water, add 15% dextrin slurry and stir well to make adhesive. In addition, put the mixture in a mixer, dry stir for 10 minutes, add 15% dextrin slurry and stir for 15 minutes to make a soft material, granulate with a 14-mesh sieve, dry at 60-70°C, and control the moisture below 2.5% .

[0028] 3. Use a 40-mesh sieve to sieve an appropriate amount of fine powder from ...

Embodiment 2

[0032] a) Prescription

[0033] Main ingredient: Domiphene 0.5g.

[0034] Excipients: 0.4g vanillin, 400g powdered sugar, 40g dextrin, 0.125g tartrazine, 0.4ml orange flavor, 0.3-0.32g dextrin slurry 15%, 7g 95% ethanol, 3g magnesium stearate, made 1000 pieces.

Embodiment 3

[0036] a) Prescription

[0037] Main ingredient: Domiphene 0.5g.

[0038] Excipients: 0.4g vanillin, 400g powdered sugar, 40g dextrin, 0.125g tartrazine, 0.4ml orange flavor, 0.3-0.32g dextrin slurry 15%, 7g 95% ethanol, 3g magnesium stearate, made 1000 pieces.

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PUM

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Abstract

The invention discloses a medicine composition for treating sphagitis, amygdalitis, thrush and ulcerative stomatitis. The medicine composition is characterized by comprising the following ingredients in parts by weight: 1-200 parts of domiphen bromide, 1-200 parts of mischobulbum element, 1-200 parts of powdered sugar, 1-200 parts of dextrin, 1-100 parts of lemon yellow, 1-50 parts of flavoring orange essence, 1-200 parts of 15% dextrin pulp, 1-50% of 95% alcohol and 1-50 parts of magnesium stearate. The medicine composition for treating the sphagitis, the amygdalitis, the thrush and the ulcerative stomatitis is convenient to carry and take, can be effectively absorbed by a mouth mucosa via sublingual administration, is good in taste and can be pleasantly accepted by adults and children.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, in particular to a pharmaceutical composition for treating pharyngitis, tonsillitis, thrush and ulcerative stomatitis. Background technique [0002] Pharyngitis is a disease caused by bacteria, which can be divided into two types: acute pharyngitis and chronic pharyngitis. Acute pharyngitis is often caused by viruses, followed by bacteria. Most common in winter and spring. Chronic pharyngitis is mainly due to the incomplete treatment of acute pharyngitis and repeated attacks, turning into chronic pharyngitis. The method for the treatment of chronic pharyngitis is a lot at present, generally advocates mouthwashes such as Koutai and compound borax solution, and takes Huasu tablets, Anji buccal tablets, g bacteria buccal tablets, etc. as western medicine generally advocates. Long-term use of these drugs can lead to environmental disturbances in the oral cavity. For hypertrophic pharyng...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/14A61K47/46A61P11/04A61P31/04A61P31/12A61P31/10A61P1/02
CPCA61K9/0056A61K9/2068A61K31/14A61K2236/333A61K2236/51
Inventor 张静吴健民刘娟
Owner KAMP PHARMA
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