32 results about "Corilagin" patented technology

The invention relates to novel application of corilagin or a pharmaceutically acceptable corilagin salt, in particular to application of the corilagin or the pharmaceutically acceptable corilagin salt in treating or preventing diseases related to gastric acid hypersecretion such as hyperchlorhydria, peptic ulcer and chronic gastritis.

The invention discloses an extraction-separation method and an application of corilagin. The method comprises the steps of treating longan kernel powder once by using anhydrous acetone and extracting by using acetone aqueous solution again for the second time; uniformly mixing a proper amount of chromatography polyamide with the acetone aqueous solution, recycling acetone and applying to a polyamide chromatography column; eluting by sequentially using pure water, methyl alcohol aqueous solutions with different concentrations and methyl alcohol; gathering 40-60 percent of methyl alcohol eluant in a separate bottle form, condensing and separating out corilagin crystals; mixing mother liquid with the rest of eluant containing corilagin, condensing to be dry, dissolving into methyl alcohol and applying to a polydextran gel LH-20 column; eluting by methyl alcohol; gathering eluant in a separate bottle form and standing; mixing with the eluants in which corilagin crystals are separated out; standing again until the orilagin crystals which are separated out are not increased; mixing the obtained corilagin crystals with corilagin crystals obtained by chromatography polyamide; performing recrystallization by using ethyl alcohol to obtain corilagin with high purity. The corilagin subjected to extraction and separation has a function of inhibiting tyrosinase.

The invention belongs to the technical field of pharmaceutic preparations containing algae, moss, fungi or plants or derivatives thereof, for example, uncertain structures of traditional herbs, and discloses a Chinese herbal medicinal ingredient prescription capable of improving swine immunosuppression and a preparation method and application of the Chinese herbal medicinal ingredient prescription. The mass ratio of corilagin, cordycepin, icariin and peoniflorin is 1-4: 1-4: 1-4: 1-4. The corilagin, the cordycepin, the icariin and the peoniflorin are added with normal saline to prepare liquidmedicine with the total concentration being 2 mg / mL according to the mass ratio of 1-4: 1-4: 1-4: 1-4. The specific antibody titer of animals can be improved effectively, the viral load is reduced, the number and activity of immunocytes and immunotransmitters are increased, growth and development of immune organs are promoted, the immunologic function and the disease resistance of the animal can be enhanced comprehensively, toxic and side effects of vaccines, chemical drugs and antibiotics and potential safety hazards of food are overcome, the research and development prospect is promising, and clinical application is wide.