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139 results about "Brain arteries" patented technology

Blood supply to the brain is normally divided into anterior and posterior segments, relating to the different arteries that supply the brain. The two main pairs of arteries are the Internal carotid arteries (supply the anterior brain) and vertebral arteries (supplying the brainstem and posterior brain).

Neuro-thrombectomy catheter and method of use

InactiveUS20020133111A1Avoid cloggingEnergy intensiveElectrotherapyCatheterThrombusCavitation
A microcatheter for removing thromboemboli from cerebral arteries in patients suffering from ischemic stroke. The microcatheter provides an extraction lumen that can be scaled to a very small diameter that is still capable of extracting and emulsifying thrombus without clogging the channel. The microcatheter of the invention uses a series of spaced apart energy application mechanisms along the entire length of the catheter's extraction lumen to develop sequential pressure differentials to cause fluid flows by means of cavitation, and to contemporaneously ablate embolic materials drawn through the extraction lumen by cavitation to thereby preventing clogging of the lumen. The catheter system thus provides a functional high-pressure extraction lumen that is far smaller than prior art catheter systems. Preferred mechanisms for energy delivery are (i) a laser source and controller coupled to optic fibers in the catheter wall or (ii) an Rf source coupled to paired electrodes within the extraction lumen. Each energy emitter can apply energy to fluid media in the extraction channel of the catheter-wherein the intense energy pulses can be sequentially timed to cause fluid media flows in the proximal direction in the channel.
Owner:SHADDUCK JOHN H

Methods of reducing embolism to cerebral circulation as a consequence of an index cardiac procedure

There is disclosed a porous emboli deflector for preventing cerebral emboli while maintaining cerebral blood flow during an endovascular or open surgical procedure. The device prevents the entrance of emboli of a size able to cause stroke (such as greater than 100 microns) from entering either the right or left common carotid arteries, and / or the right or left vertebral arteries by deflecting emboli downstream of these vessels. The device can be placed prior to any manipulation of the heart or aorta allowing maximal protection of the brain during the index procedure. The deflector has a low profile within the aorta which allows sheaths, catheters, or wires used in the index procedure to pass. Also disclosed are methods for insertion and removal of the deflector.
Owner:EDWARDS LIFESCIENCES AG

Method and system for evaluation of the hemodynamic model in depression for diagnosis and treatment

InactiveUS20090054774A1Less computation timeLow costBlood flow measurement devicesInfrasonic diagnosticsLeft posterior cerebral arteryLeft posterior
The present invention provides a method and system for determining the cerebral hemodynamic model for depression, using carotid duplex ultrasound to establish percent stenosis of the extracranial right and left internal carotid arteries and transcranial Doppler ultrasound instrument to measure mean flow velocity within the cerebral including the right and left internal carotid arteries, right and left middle cerebral arteries, right and left anterior cerebral arteries, right and left posterior cerebral arteries, and basilar artery. The percent carotid stenosis and the mean flow velocity values in cerebral arteries are used to determine the cerebral hemodynamic model associated with depression in men and women, respectively.
Owner:NJEMANZE PHILIP CHIDI

Methods of diverting embolic debris away from the cerebral circulation

There is disclosed a porous emboli deflector for preventing cerebral emboli while maintaining cerebral blood flow during an endovascular or open surgical procedure. The device prevents the entrance of emboli of a size able to cause stroke (such as greater than 100 microns) from entering either the right or left common carotid arteries, and / or the right or left vertebral arteries by deflecting emboli downstream of these vessels. The device can be placed prior to any manipulation of the heart or aorta allowing maximal protection of the brain during the index procedure. The deflector has a low profile within the aorta which allows sheaths, catheters, or wires used in the index procedure to pass. Also disclosed are methods for insertion and removal of the deflector.
Owner:EDWARDS LIFESCIENCES AG

Removal of contrast agents from blood

The invention provides a system and a method for removal of contrast from blood. In one aspect, the invention provides a catheter for removal of contrast from the veins that drain the cerebral circulation. In a second aspect, the invention provides a method for removing contrast from blood by contacting the blood with a sorbent.
Owner:UNIVERSITY OF PITTSBURGH

Everting stent and stent delivery system

Devices and methods for delivering stents to target vessel regions, including stent delivery through microcatheters to narrow cerebral arteries. One stent delivery device includes a stent having the distal region everted over the distal end of a delivery tube, having the everted stent distal end captured by a distal element of a elongate release member disposed through the delivery tube. The delivery tube can have a distal taper to a small profile distal end. The everted stent distal region can be captured between the release member distal element and the surrounding delivery tube distal region walls. The captured and everted stent can be distally advanced to a target site, followed by manipulating the release member to free the captured stent. Some devices utilize distal advancement of the release member while other devices use proximal retraction of the release member to free the captured stent distal end. Once released, the stent is free to self-expand or be expanded against the surrounding blockage and / or vessel walls. In some methods, a guide catheter or microcatheter is also included and disposed about the everted and captured stent to advance the stent, delivery tube, and release member to a location near the site to be stented. The devices and methods provide stent delivery not requiring an enclosing delivery sheath about the stent. The everted stent can thus have a very small distal profile enabling small diameter vessels to be crossed and treated.
Owner:COVIDIEN LP

Stethoscope

A simple always-portable stethoscope for enabling accurate diagnosis. A radiation / light-receiving fiber (11) serving as a probe part for noninvasively irradiating a diseased part with near-infrared light is applied to the diseased part so as to measure, e.g., a change of the cerebral circulation blood flow. The change is hard as sound pulse modulation to examine the change of the cerebral function. For example, a light beam of three wavelengths λ=760, 800, 830 nm from a semiconductor laser light source (22) is applied to the diseased part, the reflection data from the diseased part is processed by a control device (21), and the doctor can make a diagnosis with the doctor's ears by hearing with a receiver (32) the change as the change of the frequency of the sound the pitch and volume of which are constant.
Owner:JAPAN SCI & TECH CORP

Halogenated 2-(a-hydroxyl pentyl) benzoate, production method and uses thereof

The invention discloses a halogen substituted 2-(a-hydroxyl amyl) benzoate compound, a preparation method and medicinal application thereof, which belong to the technical field of organic chemical synthesis. The structural formula of the compound which is showed as above has an antimer structure, wherein <R1> represents a halogen atom; n is equal to 1 to 3; and M represents a univalent metallic ion or a bivalent metallic ion or a trivalent metallic ion or an organic base. The compound has the advantages of better activity on preventing and treating cardio-cerebral ischemia diseases, improving cardio-cerebral circulation disturbance and resisting thrombus, and the like.
Owner:ZHEJIANG AUSUN PHARMA

Blood vessel of brain circulation kinetic analysis method and apparatus

The invention relates to a brain vascular blood circulation dynamic analysis method and the apparatus thereof. According to the cerebral circulation vascular bed anatomical model, an equivalent network model which comprises 12 pipeline units simulating the brain circulation blood dynamics is built, and the relevant parameter calculation formulas are confirmed, by utilizing the formulas, the flow rate waveform and the value inside the cartid artery, the pressure waveform, the blood pressure of the body, the diameter of the blood vessel, the flow rate waveform and the valve of the vertebral artery and the front, the middle and the rear parts on two sides inside the skull, and the characteristic and the parameter of the cartid artery and each blood vessel section inside the skull can be determined, the apparatus designed by the invention can be performed, the detecting system comprises the vessel diameter detecting of the cartid artery outside the skull, the blood pressure detecting, theblood flow rate detecting of the cartid artery outside the skull, the pressure waveform detecting of the cartid artery outside the skull, and the blood flow rate detecting on the artery inside the skull; the control system comprises a control module and a power supply module; the calculation and analysis system comprises a host computer, a peripheral equipment, and an analog-digital converter, the invention can fully analyze the brain circulation dynamic characteristic, thereby having notable effect on the early stage and the ultra early stage diagnosis and therapy of the brain vascular illness.
Owner:SHANGHAI KUANGFU MEDICAL EQUIP DEV

Method of Isolating the Cerebral Circulation During a Cardiac Procedure

Single filter and multi-filter endolumenal methods and systems for filtering fluids within the body. In some embodiments a blood filtering system captures and removes particulates dislodged or generated during a surgical procedure and circulating in a patient's vasculature. In some embodiments a filter system protects the cerebral vasculature during a cardiac valve repair or replacement procedure.
Owner:BOSTON SCI SCIMED INC

Traditional Chinese medicine for treating cardiac, cerebral and vascular diseases and preparation method thereof

The invention relates to a traditional Chinese medicine for treating cardiac, cerebral and vascular diseases; the drug is composed of forty kinds of crude drugs by weight parts: milk veteh, salvia miltiorrhiza, root of common peony, ligusticum wallichii, lumbricus, sanguisuga, rhizoma acori graminei, polygala root, red ocher, oyster, angelica, the root of kudzu vine, arisaema cum bile and the like; the preparation method is that: (1) the crude drugs are prepared into water extract liquid; (2) the water extract liquid is prepared into oral liquid; (3)the water extract liquid obtained by the step (1) is dried, crushed, sieved, undersize material is extracted powder; (4) the extracted powder prepared by the step (3) is prepared into various dosage forms. The preparation method of crude powder is that: lime earth of the crude drugs is sieved, and then the crude drugs are crushed and sieved, the undersize material is taken out and is sterilized to be crude powder, and the crude powder is prepared into various dosage forms. The traditional Chinese medicine has the major functions of treating miocardial infarction and angina caused by coronary heart disease, high blood pressure and cerebral thrombosis, hemiplegia, cerebral infarction, cerebrovascular accident, sequel of apoplexy and other symptoms, and the medicine has obvious effect on headache, dizziness and heart cerebrovascular diseases caused by high blood pressure and cerebral circulation insufficiency.
Owner:卢速江

Cilostazol preparation

Provided is a cilostazol preparation which comprises incorporating a fine powder of cilostazol into a dispersing and / or solubilizing agent thereby to enhance the dispersibility and / or solubility. Further, provided is a process for improving absorbability of a slightly soluble drug such as cilostazol even at the lower portion of the digestive tract, wherein said drug is hard to be absorbed at the lower portion of the digestive tract when a conventional method is used. According to the present invention, cilostazol is absorbed enough even at the lower portion of the digestive tract to have an effect as thrombolytic drug, cerebral circulation improving drug or the like.
Owner:OTSUKA PHARM CO LTD

Retrograde venous perfusion with isolation of cerebral circulation

A medical device for providing retrograde venous perfusion to the cerebral vasculature for treatment of global or focal cerebral ischemia is disclosed. The device includes a catheter having an infusion port at its distal end, venous drainage port(s), and an expandable occluder disposed between the infusion port and drainage port(s). The catheter can be inserted into the superior vena cava or the internal jugular vein. The catheter is attached proximally to a pump and an oxygenator with or without a cooling system. Alternatively, the device includes two catheters, each having a lumen communicating with a distal infusion port and an occluder mounted proximal to the port. The catheters can be inserted into the internal jugular veins distal to jugular venous valves. Methods of using the devices to provide retrograde venous perfusion and isolated cerebral hypothermia are disclosed.
Owner:ZOLL CIRCULATION

Medicinal composition for prevention of or treatment for cerebrovascular disorder and cardiopathy

A pharmaceutical composition comprising at least one of components (a) and at least one of components (b) shown in below: (a) a compound represented by the general formula (I) (wherein R1 represents a hydrogen atom or a hydroxyl group) or an acid addition salt or hydrate thereof; and (b) an ameliorant of cerebral circulation, a vasodilator, a cerebral protecting drug, an brain metabolic stimulants, an anticoagulant, an antiplatelet drug, a thrombolytic drug, an amelirant of psychiatric symptom, a antihypertensive drug, an antianginal drug, a diuretic, a cardiotonic, an antiarrhythmic drug, an antihyperlipidemic drug, an immunosuppressant, or a pharmaceutically acceptable salt (except the components shown in (a)). It is useful as a preventive or remedy for cerebrovascular disorders and cardiac diseases.
Owner:ASAHI KASEI PHARMA

Cognitive performance assessment test

This document provides systems and methods for testing and assessing cognitive performance of a user over a period of time in order to test environmental effects and other factors on the performance of the user. For example, cognitive performance over a period of time can be assessed for users experiencing stress conditions including hypoxia (oxygen deprivation), hypothermia, sleep deprivation, fatigue or other factors that may cause degradation in cognitive performance. Furthermore, the systems and methods described herein can be used to identify when hypoxia has manifested in the cerebral circulation of an individual rather than merely in the extremities of an individual.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES

Analytical system and analytical method for property of blood vessel of brain and blood flow behavior

The invention belongs to the human biological parameter detection and analysis system field, and particularly relates to a brain blood vessel feature and blood flow characteristics analysis system and an analysis method thereof. The analysis system comprises a human biological signal reception part, a main processing part, a control input part, and an output part. Human biological signals collected by the human biological signal reception part are transmitted to the main processing part for data processing after A / D transformation and then are outputted by the output part, and the control input part sends corresponding control signals into the main processing part to complete corresponding data processing. The analysis method comprises: 1) a construction stage of basic data of the brain blood vessel system feature; 2) an evaluation preparation stage of the brain blood vessel system; 3) indirectly working out the elasticity cardinal number of each blood vessel branch displaying feature variance in front, middle and rear brain artery systems. The analysis system and method collects related human biological parameters through a noninvasive measuring method, thereby completing the early diagnosis of human cerebrovascular diseases.
Owner:金寿山 +1

Cerebral blood flow regulation function monitor system and method for detecting cerebral circulation critical closing pressure

A cerebrovascular regulation function monitor system and a method for detection of cerebrovascular circulation critical closing pressure, wherein the cerebrovascular regulation function monitor system includes a signal collection system for in-phase sampling analog signal of transcranial doppler (TCD) signal and continuous artery pressure signal and further converting the analog signals into correspondent digital signals and a signal processing / displaying system connected with the signal collection system via interfaces for processing the digital signals to obtain the cerebrovascular critical closing signal and displaying them. The method and system realize a non-invasion detection and monitor of cerebrovascular autoregulation function in clinical practice.
Owner:SHENZHEN DELICA MEDICAL EQUIP CO LTD +1

Devices and methods for preventing distal embolization using flow reversal and perfusion augmentation within the cerebral vasculature

InactiveUS20050090854A1Prevention of distal embolizationMinimizing blood lossBalloon catheterSurgeryAtherectomyBlood flow
A medical device having a catheter and one or more expandable constricting / occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter. A first constrictor / occluder mounted at the distal end of the catheter is adapted for placement in a brachiocephalic or subclavian artery. A second constrictor mounted proximal to the first constrictor / occluder is adapted for placement in the descending aorta. Pressure measuring devices may be included, and filters may be used to capture embolic debris. Methods of using the devices for preventing distal embolization during extracranial or intracranial carotid procedures or vertebral artery procedures by augmenting collateral cerebral circulation by coarctation of the aorta to enhance reversal of blood flow in an internal carotid artery, an external carotid artery, and / or a common carotid artery toward the subclavian artery are disclosed.
Owner:ZOLL CIRCULATION

Image processing method for estimating a brain shift in a patient

InactiveUS20110257514A1Rapid and robust and precise responseImage enhancementImage analysisSurgical operationImaging processing
The disclosure relates to an image processing method for estimating a brain shift in a patient, the method involving: the processing of a three-dimensional image of the brain of a patient, acquired before a surgical operation, in order to obtain a reference cerebral arterial tree structure of the patient; the processing of three-dimensional images of the brain of the patient, acquired during the operation, in order to at least partially reconstitute a current cerebral arterial tree structure of the patient; the determination from the combination of the reference and current cerebral arterial tree structures, of a field of shift of the vascular tree representing the shift of the current vascular tree in relation to the reference vascular tree; the application of the determined field of shift of the vascular tree to a biomechanical model of the brain of the patient in order to estimate the brain shift of the patient; and the generation, from the estimated brain shift, of at least one image of the brain of the patient, in which the brain shift is compensated.
Owner:UNIV JOSEPH FOURIER +1

Vinpocetine containing high-capacity sodium chloride injection and preparation method thereof

The invention provides a vinpocetin containing high-capacity sodium chloride injection and a preparation method thereof, aiming at solving the problems that vinpocetin is mainly applied to middle aged and elderly patients, high-capacity glucose injection contains massive glucose and is not beneficial to treating patients suffering from diabetes at the same time. The invention has the key point that the injection is mainly composed of vinpocetin, osmotic pressure regulator, cosolvent and pH value regulator. The vinpocetin high-capacity sodium chloride injection of the invention has high bioavailability and stable quality, is convenient to use and is applicable to treatment of patients suffering from neurologic disease caused by cerebral circulation restriction, especially the patients suffering from diabetes at the same time.
Owner:SHENYANG ZHIYING PHARMA FACTORY

Application of Tibetan medicinal composition to preparation of medicament for treating cerebral circulation insufficiency

The invention discloses application of a Tibetan medicinal composition to the preparation of a medicament for treating cerebral circulation insufficiency. The Tibetan medicinal composition consists of the following raw material medicaments in part by weight: 5 to 15 parts of lamiophlomis, 2 to 10 parts of whin, 15 to 60 parts of turmeric, 7 to 20 parts of pepper, 5 to 15 parts of buffalo horn, 15 to 40 parts of myricariagermanica, 0.1 to 2.5 parts of safflower, 0.1 to 5 parts of borneol and 0.1 to 5 parts of camphor. Further research on the pharmacology of the conventional Tibetan medicinal composition indicates that the Tibetan medicinal composition has good curative effect on cerebral circulation insufficiency. Moreover, natural wild medicinal materials from the Tibet Plateau are adopted and no chemically-synthesized stabilizing agent is added, so that the Tibetan medicinal composition has no toxic or side effect on a human body, is safe and effective and is suitable for all kinds of people and for treating various types of cerebral circulation insufficiency.
Owner:TIBET QIZHENG TIBETAN MEDICINE

A traditional Chinese medicine preparation for treating chronic cerebral insufficiency

The invention relates to a Chinese medicinal preparation for treating chronic cerebral circulation insufficiency. The Chinese medicinal preparation is prepared from the following traditional Chinese medicines: 30 grams of astragalus, 15 grams of kudzuvine root, 15 grams of Chinese taxillus twig, 30 grams of root of red-rooted salvia, 9 grams of raw fructus crataegi, 9 grams of szechuan lovage rhizome, 10 grams of cassia twig, 12 grams of dwarf lilyturf root, 6 grams of Chinese magnoliavine fruit and 15 grams of fried date kernel. A preparation method of the Chinese medicinal preparation comprises the following steps of: adding 1,000 ml of water into the Chinese medicinal herbs subjected to processing for decocting; concentrating the decoction to 200 ml; and extracting residues and filtering to obtain a decoction. The Chinese medicinal preparation is taken once every day, and each treatment course lasts for two weeks. The Chinese medicinal preparation has the effects of replenishing qi, enriching the blood, relaxing muscles and joints, activating the channels, remarkably improving heart and brain circulation, enhancing mechanism immunity, resisting inflammation, delaying senility, treating both principal and secondary aspects of a disease, and the like, has reasonable compatibility, and can be used for effectively relieving symptoms such as dizziness, head heaviness, headache, dysphoria, tinnitus, irritability, insomnia, dreaminess, hypomnesia, inattention, fatigue, and the like of a patient suffering from chronic cerebral circulation insufficiency.
Owner:刘红

Chinese medicinal preparation for treating chronic cerebral circulation insufficiency

The invention relates to a Chinese medicinal preparation for treating chronic cerebral circulation insufficiency. The Chinese medicinal preparation is prepared from the following traditional Chinese medicines: 30 grams of astragalus, 15 grams of kudzuvine root, 15 grams of Chinese taxillus twig, 30 grams of root of red-rooted salvia, 9 grams of raw fructus crataegi, 9 grams of szechuan lovage rhizome, 10 grams of cassia twig, 12 grams of dwarf lilyturf root, 6 grams of Chinese magnoliavine fruit and 15 grams of fried date kernel. A preparation method of the Chinese medicinal preparation comprises the following steps of: adding 1,000 ml of water into the Chinese medicinal herbs subjected to processing for decocting; concentrating the decoction to 200 ml; and extracting residues and filtering to obtain a decoction. The Chinese medicinal preparation is taken once every day, and each treatment course lasts for two weeks. The Chinese medicinal preparation has the effects of replenishing qi, enriching the blood, relaxing muscles and joints, activating the channels, remarkably improving heart and brain circulation, enhancing mechanism immunity, resisting inflammation, delaying senility, treating both principal and secondary aspects of a disease, and the like, has reasonable compatibility, and can be used for effectively relieving symptoms such as dizziness, head heaviness, headache, dysphoria, tinnitus, irritability, insomnia, dreaminess, hypomnesia, inattention, fatigue, and the like of a patient suffering from chronic cerebral circulation insufficiency.
Owner:刘红

Method and instrument for analyzing energy indexes of cerebral blood vessel

The invention discloses a method and an instrument for analyzing the energy indexes of the cerebral blood vessel. The method comprises the steps of: detecting out the blood flow velocity wave form, the numerical value, the blood vessel diameter and the pressure waveform of carotid artery; detecting out the diastolic pressure and the systolic pressure of a human body to obtain the pressure waveform and the numerical value of the carotid artery; then calculating out the total potential energy, the stable potential energy, the oscillation potential energy, the total kinetic energy, the stable kinetic energy, the oscillation kinetic energy, the total energy, the stable total energy and the oscillation total energy of the cerebral blood vessel, and finally calculating out the ration of the oscillation total energy to the total energy, the ratio of the total kinetic energy to the total energy, the ratio of the oscillation potential energy to the total potential energy and the ratio of the oscillation kinetic energy to the total kinetic energy of the cerebral blood vessel. The detection analysis instrument comprises a detection system, a control system and a computation analysis system, wherein the control system can send an operation command to each detection module and can also transmit the acquired data information to a master industrial personal computer. A series of indexes of the cerebral circulation blood flow energy can be comprehensively analyzed with an invasive method, therefore, the invention has great importance for the basic research and clinical application of the cerebral circulation.
Owner:SHANGHAI KUANGFU MEDICAL EQUIP DEV
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