43 results about "External carotid artery" patented technology

Methods and apparatus are provided for removing emboli during an angioplasty, stenting or surgical procedure comprising a catheter having an occlusion element, an aspiration lumen, and a blood outlet port in communication with the lumen, a guide wire having a balloon, a venous return sheath with a blood inlet port, and tubing that couples the blood outlet port to the blood inlet port. Apparatus is also provided for occluding the external carotid artery to prevent reversal of flow into the internal carotid artery. The pressure differential between the artery and the vein provides reverse flow through the artery, thereby flushing emboli. A blood filter may optionally be included in-line with the tubing to filter emboli from blood reperfused into the patient.

Methods and apparatus are provided for removing emboli during an angioplasty, stenting or surgical procedure comprising a catheter having an occlusion element, an aspiration lumen, and a blood outlet port in communication with the lumen, a guide wire having a balloon, a venous return catheter with a blood inlet port, and tubing that couples the blood outlet port to the blood inlet port. Apparatus is also provided for occluding the external carotid artery to prevent reversal of flow into the internal carotid artery. The pressure differential between the artery and the vein provides reverse flow through the artery, thereby flushing emboli. A blood filter may optionally be included in-line with the tubing to filter emboli from blood reperfused into the patient.

Methods and apparatus are provided for removing emboli during an angioplasty, stenting or surgical procedure comprising a catheter having an occlusion element, an aspiration lumen, and a blood outlet port in communication with the lumen, a guide wire having a balloon, a venous return catheter with a blood inlet port, and tubing that couples the blood outlet port to the blood inlet port. Apparatus is also provided for occluding the external carotid artery to prevent reversal of flow into the internal carotid artery. The pressure differential between the artery and the vein provides reverse flow through the artery, thereby flushing emboli. A blood filter may optionally be included in-line with the tubing to filter emboli from blood reperfused into the patient.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter. The constrictor / occluder is mounted at the distal end of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during extracranial or intracranial carotid procedures or vertebral artery procedures by reversing blood flow in an internal carotid artery, an external carotid artery, and / or a common carotid artery toward the subclavian artery are disclosed.

An implantable device for positioning in the vicinity of the bifurcation of the common carotid artery (CCA) into the internal carotid artery (ICA) and the external carotid artery (ECA), comprises a deflecting element suitable to deflect the flow of embolic material flowing in the CCS toward the ICA, into the ECA, without filtering.

The present invention concerns a process for making a virtual stent for implantation into a body lumen. A particularly preferred embodiement is optmized for emplacement and indwelling in the internal carotid artery, with a lower end and an upper end wherein the radius decreases from lower end to upper end, and includes "trumpet-like' or parabolic elements abutting facultative apertures. Generally, computer-aided-design derived stent has a tectonic structure in the form of angles and curvatures adapted to the course of a desired lumen. For example, the internal carotid artery whereby lower end in the region of the outlet of internal carotid artery is formed as an ovaloid recess provided in the region of the outlet of the external carotid artery.

An apparatus and a system can chronically and automatically measure a physiologic parameter associated with the high pressure side of the vasculature and / or regulate blood pressure based upon the measured parameter. The apparatus may be made up of a transducer, a baroreflex activation device having one or more electrodes, and a lead having two or more conductors. The system can measure a physiologic parameter and selectively administer a therapy, such as, for example, electro-stimulation of baroreceptors, based upon the measurement. The transducer for measuring the physiologic parameter can be chronically implanted in the high-pressure side of the vasculature. The implantation method may include intravascularly positioning the transducer in the external carotid artery in such a way that the transducer is first introduced into the arterial vasculature through the superior thyroid artery.

An apparatus and a system can chronically and automatically measure a physiologic parameter associated with the high pressure side of the vasculature and / or regulate blood pressure based upon the measured parameter. The apparatus may be made up of a transducer, a baroreflex activation device having one or more electrodes, and a lead having two or more conductors. The system can measure a physiologic parameter and selectively administer a therapy, such as, for example, electro-stimulation of baroreceptors, based upon the measurement. The transducer for measuring the physiologic parameter can be chronically implanted in the high-pressure side of the vasculature. The implantation method may include intravascularly positioning the transducer in the external carotid artery in such a way that the transducer is first introduced into the arterial vasculature through the superior thyroid artery.

The invention provides a method and system for introducing cool fluid to a targeted treatment site, such as, for example, a stroke-affected brain hemisphere. In one approach, the method generally includes introducing a catheter into a branch artery of the external carotid artery, and introducing fluid into the ipsilateral internal carotid artery. In one approach, a balloon is used to occlude the external carotid artery during introduction of the fluid into the internal carotid artery.

The invention relates to a method for establishing a rat external carotid artery catheter-indwelled cerebral ischemia reperfusion model. The method includes the following steps that: the direction of an external carotid artery blood vessel of a rat is drifted, the direction of the external carotid artery blood vessel of the rat is drifted to a position which is consistent with or parallel to the direction of an internal carotid artery blood vessel of the rat; the external carotid artery blood vessel is cut, a suture is inserted into an incision, so that cerebral ischemia can be formed in the neck of the rat; and 1 to 2 hours after the suture is inserted into the incision, and cerebral ischemia is formed, the suture is pulled out, and a catheter injection bag through which medicine can be injected repeatedly is arranged into the external carotid artery blood vessel. According to the method, an external carotid artery suture method is adopted to manufacture the rat ischemia reperfusion model, and therefore, the normal structures of an operation-side common carotid artery and an internal carotid artery can be protected; the catheter injection bag through which medicine can be injected repeatedly is indwelled in the external carotid artery, medicine can be injected into the internal carotid artery through the artery catheter repeatedly at different time points; nerve functional assessment after the model is established can be realized, and qualified animals could be accepted and subjected to experimental intervention, and therefore, the scientific nature of experiments can be greatly improved.

A medical device having a catheter and one or more expandable constricting / occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter. A first constrictor / occluder mounted at the distal end of the catheter is adapted for placement in a brachiocephalic or subclavian artery. A second constrictor mounted proximal to the first constrictor / occluder is adapted for placement in the descending aorta. Pressure measuring devices may be included, and filters may be used to capture embolic debris. Methods of using the devices for preventing distal embolization during extracranial or intracranial carotid procedures or vertebral artery procedures by augmenting collateral cerebral circulation by coarctation of the aorta to enhance reversal of blood flow in an internal carotid artery, an external carotid artery, and / or a common carotid artery toward the subclavian artery are disclosed.

A system for treating a medical condition in a living body, comprising two subsystems, an implant subsystem and an electrical stimulation unit subsystem. The implant subsystem comprises at least one electrostimulation module, contains at least one electrically conductive electrode and, preferably, an anchoring member. The electrical stimulation unit, adapted for producing and controlling electrical waveforms, is connected to the electrodes. The implant subsystem is implanted adjacent to at least one of the following structures: the carotid sinus nerve, aortic nerve, common carotid artery, external carotid artery, internal carotid artery, carotid artery bifurcation, carotid body, aortic body or aortic arch receptors. The electrical stimulation unit is maintained outside the patient's body and is adapted to program, generate, control and deliver the electrical waveform via a wired or a wireless connection to the implant subsystem, thereby stimulating the structure it is adjacent to and treating the medical condition.

The invention provides a preparation method for a mouse thrombotic stroke model. The method comprises the following steps: after anesthetizing a mouse, making a slipknot on a common carotid artery byusing a suture line, and separating and permanently ligating an external carotid artery and a pterygopalatine artery; separating the initial part of an internal carotid artery; putting the common carotid artery into a groove of a blood vessel electric shock clip of a thrombus generator, and carrying out electrical stimulation to form a thrombus; taking off the electric shock clip and clipping thedistal end of the common carotid artery; crushing the thrombus by using a pair of microscope forceps, enabling the artery to pulsate again, and impacting and crushing the thrombus; releasing an arteryclip; after expelling the thrombus to enter the internal carotid artery by using the forceps, immediately closing the proximal end of the common carotid artery; and opening all artery clips after pre-set time, so as to form a target thrombus model. The mouse thrombotic stroke model provided by the invention can be applied to researches of treatment medicines and methods for stroke, and pathogenesis.

The present invention provides a method and device for preventing cerebral embolization during endovascular procedures in the carotid arteries. The invention comprises a guide catheter and balloon, which may selectively occlude the common carotid artery, and further comprises a wire and balloon, which may selectively occlude the internal carotid artery. Occlusion of the common carotid artery will induce retrograde flow at the site, redirecting emboli to the external carotid artery. Occlusion of the internal carotid artery reduces the risk of emboli migrating to the brain, and allows clearance of the site by antegrade blood flow from the common carotid artery. Occlusion of both the common and internal carotid arteries induces a quiescent state at the site during the procedure. Control of blood flow by selective inflation and deflation of either or both balloons, in concert with the procedures, will reduce the risk of emboli migrating to the brain.

The invention belongs to the field of medical apparatus and instruments, and in particular relates to a skin-outer carotid sinus massage blood-pressure-reducing device. The skin-outer carotid sinus massage blood-pressure-reducing device comprises a carotid sinus massage part, a pressure monitoring part, a control part, a display part, an electrocardiogram monitoring part and a fixing part, wherein a microprocessor of the control part analyzes a pressure signal from the pressure monitoring part, so that the massage mode of the carotid sinus massage part fixed to the local skin-outer part of the carotid sinus is adjusted, and thus the feedback blood pressure reduction is realized. The skin-outer carotid sinus massage blood-pressure-reducing device is used for treating high blood pressure, is a noninvasive blood pressure reducing device, is convenient to use, is safe and effective, and has a great clinical application value.

The invention discloses an intracranial aneurysm detection method based on MRA, and the method comprises the following steps: obtaining to-be-processed original image data, carrying out the correction and normalization processing of the original image data, and obtaining the processed image data; performing mIP reconstruction on the processed image data to obtain MIP images, and generating three kinds of rotating images after the external carotid artery is deleted, wherein each rotating image is composed of projections evenly distributed around a single rotating shaft; automatically segmenting intracranial artery blood vessel voxels; manufacturing a plurality of patches for each voxel in the blood vessel area, calculating the probability that all patches contain the aneurysm, classifying the calculated probabilities according to a preset probability threshold value, wherein the voxels larger than the preset probability threshold value generate a volume shape index image and a curvature image based on a curvature algorithm to display the aneurysm; measuring the maximum diameter of the aneurysm; and outputting an aneurysm detection result. According to the method, the intracranial artery blood vessel can be accurately identified, and the size of the aneurysm can be accurately measured.

Multiple catheters are used to improve the positioning of devices for the treatment of stenosis in carotid arteries. A first catheter is introduced through the right common femoral artery and used to position a first balloon occluder within the external carotid artery. A second catheter is introduced through the left common femoral artery and used to position a balloon occluder catheter within the common carotid artery after removal of the first catheter. A guide wire is used to guide a self-expanding stent through the balloon occluder catheter adjacent a narrowing or stenosis within the carotid artery for treatment. The utilization of multiple catheters makes possible the positioning of devices used to treat stenosis easier and in locations that have been difficult to treat.

The invention discloses a method for building a stenosis model after rat carotid artery balloon injuries. The method includes the steps of injecting pentobarbital sodium to the abdominal cavity of a rat to anesthetize the rat, removing furs to prepare the skin, enabling the rat to be fixed on an operation table in a supination mode, cutting the rat along the right middle line of the neck, exposing the left common carotid artery, disinfecting the skin at the position of the groin on the right side of the rat, separating the femoral artery, conducting ligation on the far-heart end at the position 1cm below the branch of the femoral artery, using a needle of a 1m1 injection syringe to puncture the femoral artery, feeding a super-smooth guide wire through the needle of the injection syringe into the carotid artery on the left side, feeding a balloon into the carotid artery on the left side along the super-smooth guide wire, feeding a balloon catheter into the bifurcated position of the internal carotid and external carotid artery of the left side of the neck, enabling the pressure in the balloon to be 1.0 barometric pressure to enable the balloon to right be capable of being pulled in the blood vessel, expanding the balloon to drag the balloon back and forth three times to strip the inner skin to enable the carotid artery to be damaged, withdrawing the balloon catheter, conducting ligation on the near-heart end of a notch of the artery, sewing the skin, and injecting penicillin into the muscle for continuous three days after an operation to avoid infections. According to the method, the operative difficulty in the prior art is reduced, the modeling success rate is improved, and the complication is reduced.

The invention discloses an implantable internal carotid artery constant-speed injection device and an operation method thereof. A sealing cover and a sealing plug which not only have a sealing effect,but also can be pierced by a needle are separately arranged at the top end and the rear end of a common carotid artery implanting guide tube, an injection opening which is covered by a one-way circulating door is formed in the front end of the common carotid artery implanting guide tube, flow speed and time are controlled through a controller, a constant-speed injection micro-pump is driven to push an injection syringe, and cancer cells or injection drugs flow into common carotid artery blood vessels through an injection opening of the common carotid artery implanting guide tube. By the implantable internal carotid artery constant-speed injection device, a surgical method can be simple and convenient, surgical steps are simplified, and surgery time is shortened; and meanwhile, a surgery mode of for an animal model of mouse internal carotid artery injection will be changed completely, the external carotid artery of a mouse does not need to be sutured, pneumogastric nerves and blood vessels cannot be damaged, and the success rate of the surgery is greatly increased.

A device (10) for assessing a patient's absolute and / or relative risk of cognitive decline and / or dementia, the device (10) comprising: a probe (12) configured to be placed adjacent to a patient's common carotid artery, internal carotid artery or external carotid artery, at least two sensors (101, 102, 104, 106, 108, 110) associated with the probe (12), the sensors being configured to measure one or more of: wave intensity of carotid pulse; wave power of carotid pulse; and pressure waveform of carotid pulse, pulse wave velocity, artery compliance, artery stiffness, artery diameter; micro-emboli count; Heart rate variability; and changes to the eye or retina.

The invention provides a Y-shaped carotid artery stent with an absorbable self-protruding membrane branch, so as to treat carotid artery stenosis. The Y-shaped carotid artery stent is characterized bycomprising an inner net pipe, which is a hollow pipe; an outer net pipe, which is arranged on the outer wall of the inner net pipe in a sleeving manner; and a membrane pipe, which is mounted betweenthe inner net pipe and the outer net pipe and is arranged on the outer wall of the inner net pipe in a sleeving manner, wherein each of the inner net pipe, the outer net pipe and the membrane pipe hasa trunk part, a first branch part and a second branch part opposite to the first branch part; one end of the trunk part is communicated with the ends of the corresponding first branch part and the corresponding second branch part to form an integrated Y shape matched with the shape of a bifurcation structure; the trunk parts are placed in the common carotid artery; the corresponding first branchparts are placed in the internal carotid artery; the corresponding second branch parts are placed in the external carotid artery; the inner net pipe and the outer net pipe are both pipes of mesh structures made of memory metal wires; and the pore size of the inner net pipe is less than that of the outer net pipe.

The invention discloses a novel construction method of a cerebral metastatic tumor animal model through carotid artery injection, and relates to the field of animal model construction methods. Comprising the following steps: 1) permanent ligation of the external carotid artery; (2) temporarily blocking the proximal end of the common carotid artery; 3) injecting tumor cells into the common carotid artery; 4) temporarily blocking the telecentric end of the common carotid artery to prevent blood backflow; 5) repairing an injection puncture point with hydrogel; and 6) sequentially loosening the blocking of the telecentric end and the proximal end of the common carotid artery. According to the modeling method, the needed time is short, the technical means difficulty is low, the internal carotid artery is kept unobstructed in the mode of ligating the external carotid artery, intracranial hemodynamics is not obviously changed, the death rate and the postoperative cerebral infarction rate caused by the traditional modeling process are greatly reduced, and the modeling method is suitable for large-scale popularization and application. The process is closer to the process that peripheral tumors enter the encephalic through the internal carotid artery and are colonized in the natural state.

The invention provides a sectional composite dense net structure carotid artery stent used for being arranged at a divaricate structure of the internal carotid and external carotid artery connected with the common carotid artery so as to treat carotid artery stenosis. The carotid artery stent is characterized by comprising a first supporting tube and a membrane tube, wherein the first supporting tube is in the shape of a conical hollow tube matched with the shapes of the common carotid artery and the internal carotid and is used for being arranged in the common carotid artery and the internalcarotid to further support the common carotid artery and the internal carotid; the membrane tube is arranged on the outer wall of the first supporting tube in a sleeving manner and comprises two straight tube sections and an annular protrusion section connected with the two straight tube sections; the first supporting tube is a tube of a mesh structure made from memory metal wires; the wall thickness of the annular protrusion section is smaller than that of the straight tube section.

The invention relates to the technical field of animal model construction, and discloses a construction method of a novel brain metastatic tumor animal model. The construction method disclosed by the invention comprises the following steps: separating a left common carotid artery and a left common carotid artery branch of the neck of a mouse; rotating the head of the mouse, lifting up a common carotid artery traction silk suture, and then temporarily blocking the common carotid artery; lifting up the telecentric end of the external carotid artery, and leading tumor cell suspension into an internal carotid artery towards the proximal end; and after completing leading in the tumor cell suspension, closing an external carotid artery, and opening the common carotid artery. According to the construction method, the pathophysiological process of human tumor brain metastasis is well simulated, the bleeding amount and the probability of tumor cell leakage in the modeling operation are reduced, the modeling success rate is increased, and the death rate of a model is reduced; and the prepared brain metastasis tumor animal model avoids metastasis of multiple organs, the whole-body tumor load of the mouse is reduced, and the mouse model prepared by the construction method can be used for researching the metastasis mechanism and tumor microenvironment of the brain metastasis tumor.

The invention belongs to the technical field of medical instruments, and particularly relates to a covered stent. The covered stent comprises a stent body and a filter membrane; the stent body is provided with a near end and a far end, and the near end is used for being arranged on the upstream of a blood vessel relative to the far end. The filter membrane is provided with a mounting part and a dissociation part, the mounting part is connected to the stent body, and the dissociation part is connected with the mounting part and dissociates from the stent body. After the stent body is installedat a Y-shaped bifurcation of a carotid artery, the stent body is opened, the filter membrane is opened along with the stent body, and the filter membrane covers plaques in blood vessels, so that the plaques can be prevented from being broken and falling off due to extrusion of the stent body. Besides, after the stent body is installed on the common carotid artery and the internal carotid artery, blood flow entering the external carotid artery from the common carotid artery easily rushes through the filter membrane located at the entrance of the external carotid artery, and therefore it is guaranteed that the blood normally enters the external carotid artery. Compared with the prior art, the covered stent is better in use safety.

An ultrasound imaging system provides coronal and transverse images for guiding a superior temporal artery guidewire (STA guidewire) through a tortuous region of the STA to an aortic arch region for snaring by a femoral artery catheter snare and pulling through for “through and through” guidewire access. The STA guidewire includes a knob at a distal end which is advanced into a superficial temporal artery (STA) using multi-plane ultrasound guidance, and the STA guidewire is guided through the tortuous region using transverse and coronal images provided by the multi-plane ultrasound imager. The transverse and coronal images indicate the rotational direction for the wire tip to advance the knob end of the STA guidewire within the STA to the external carotid artery.