214 results about "Aortic arch" patented technology

The invention provides a method and system for treating disorders in parts of the body. A particular treatment can include on or more of, or some combination of: ablation, nerve modulation, three-dimensional tissue shaping, drug delivery, mapping stimulating, shrinking and reducing strain on structures by altering the geometry thereof and providing bulk to particularly defined regions. The particular body structures or tissues can include one or more of or some combination of region, including: the bladder, esophagus, vagina, penis, larynx, pharynx, aortic arch, abdominal aorta, thoracic, aorta, large intestine, sinus, auditory canal, uterus, vas deferens, trachea, and all associated sphincters. Types of energy that can be applied include radiofrequency, laser, microwave, infrared waves, ultrasound, or some combination thereof. Types of substances that can be applied include pharmaceutical agents such as analgesics, antibiotics, and anti-inflammatory drugs, bulking agents such as biologically non-reactive particles, cooling fluids, or dessicants such as liquid nitrogen for use in cryo-based treatments.

A method for deploying a cardiac-assist device is disclosed. In accordance with the illustrative embodiment, an introducing tube, such as a catheter, sheath, or the like is inserted into the vascular system and advanced beyond the aortic arch. The cardiac-assist device is then inserted into the tube, advanced through it, and deployed from its distal end. In some embodiments, the diameter of the cardiac-assist device expands when it deploys from the distal end of the tube.

A ventricular assist device includes a pump such as an axial flow pump, an outflow cannula connected to the outlet of the pump, and an anchor element. The anchor element is physically connected to the pump, as by an elongate element. The pump is implanted within the left ventricle with the outflow cannula projecting through the aortic valve but desirably terminating short of the aortic arch. The anchor element is fixed to the wall of the heart near the apex of the heart so that the anchor element holds the pump and outflow cannula in position.

A guiding catheter for use in coronary angioplasty and other cardiovascular interventions which incorporates a plurality of segment of selected flexural modulus in the shaft of the device. The segments which have a different flexibility than the sections immediately proximal and distal to them, creating zones in the catheter shaft which are either more or less flexible than other zones of the shaft. The flexibility and length of the shaft in a given zone is then matched to its clinical function and role. A mid-shaft zone is significantly softer than a proximal shaft or distal secondary curve to better traverse the aortic arch shape without storing too much energy. A secondary zone section is designed to have maximum stiffness to provide optimum backup support and stability.

Patients having diminished circulation in the cerebral vasculature as a result of stroke or from other causes such as cardiac arrest, shock or head trauma, or aneurysm surgery or aortic surgery, are treated by flowing an oxygenated medium through an arterial access site into the cerebral vasculature and collecting the medium through an access site in the venous site of the cerebral vasculature. Usually, the cold oxygenated medium will comprise autologous blood, and the blood will be recirculated for a time sufficient to permit treatment of the underlying cause of diminished circulation. In addition to oxygenation, the recirculating blood will also be cooled to hypothermically treat and preserve brain tissue. Isolation and cooling of cerebral vasculature in patients undergoing aortic and other procedures is achieved by internally occluding at least the right common carotid artery above the aortic arch. Blood or other oxygenated medium is perfused through the occluded common carotid artery(ies) and into the arterial cerebral vasculature. Usually, oxygen depleted blood or other medium leaving the cerebral vasculature is collected, oxygenated, and cooled in an extracorporeal circuit so that it may be returned to the patient. Occlusion of the carotid artery(ies) is preferably accomplished using expansible occluders, such as balloon-tipped cannula, catheters, or similar access devices. Access to the occlusion site(s) may be open surgical, percutaneous, or intravascular.

The invention provides a method and system for treating disorders in parts of the body. A particular treatment can include on or more of, or some combination of: ablation, nerve modulation, three-dimensional tissue shaping, drug delivery, mapping stimulating, shrinking and reducing strain on structures by altering the geometry thereof and providing bulk to particularly defined regions. The particular body structures or tissues can include one or more of or some combination of region, including: the bladder, esophagus, vagina, penis, larynx, pharynx, aortic arch, abdominal aorta, thoracic, aorta, large intestine, sinus, auditory canal, uterus, vas deferens, trachea, and all associated sphincters. Types of energy that can be applied include radiofrequency, laser, microwave, infrared waves, ultrasound, or some combination thereof. Types of substances that can be applied include pharmaceutical agents such as analgesics, antibiotics, and anti-inflammatory drugs, bulking agents such as biologically non-reactive particles, cooling fluids, or dessicants such as liquid nitrogen for use in cryo-based treatments.

A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis.

A device, system and method for the generation of therapeutic acoustic shock waves for at least partially separating a deposit from a vascular structure. The shock waves may optionally be generated according to any mechanism which is known in the art, including but not limited to, spark gap technology, electromagnetic shock wave generation and piezoelectric technology for generating therapeutic pressure pulses. Examples of deposits which may be treated with the present invention include, but are not limited to, atherosclerotic plaques, any type of clot, and any type of thrombus or embolus. The vascular structure itself may be any such structure for conducting blood flow, including but not limited to arteries, veins and the aortic arch.

A catheter device (1) is disclosed for transvascular delivery of a medical device to a cardiac valve region of a patient. The catheter device comprises an elongate sheath (2) with a lumen and a distal end (3) for positioning at a heart valve (6), and a second channel (7) that extends parallel to, or in, said elongate sheath, an expandable embolic protection unit (8), such as a filter, wherein at least a portion of the expandable embolic protection unit is arranged to extend from an orifice of the second channel, wherein the embolic protection unit is non-tubular, extending substantially planar in the expanded state for covering ostia of the side branch vessels in the aortic arch.

Devices and methods that regulate the innervation of the kidney by detection and modification of the aorticorenal ganglion. Devices for percutaneous detection and treatment of the aorticorenal ganglion via a blood vessel to modify renal sympathetic activity.

Filtration systems with integrated filter element(s) forming portions of the wall of the filtration catheter are disclosed. The filtration catheters disclosed herein are designed to be used alone or in conjunction with another filter device to provide embolic protection of both carotid arteries. Occlusive element such as balloon is placed on the exterior of the filtration catheter to redirect blood flow in the vessels during the filtration process as well as to help anchor the filtration catheter inside the vessel. The integrated filter element(s) does not require collapsing thus significantly reduces the complexity of the filtration system retrieval process and the chances of releasing emboli back into the blood stream. The compact design of the filtration systems makes them particularly suitable for embolic protection during endovascular procedures on or close to the heart.

Methods and apparatus for aiding in support and repair of a thoracic aneurysm of the aortic arch. A stent graft provides a window therein, which enables blood to flow freely into branch vessels which would otherwise be occluded by the stent graft. Additionally, the stent portions of the stent graft are configured to minimize the risk of overexpansion, wherein stents are provided in the window portion.

The use of bifurcated catheter is disclosed for stabilizing working catheters for carotid percutaneous intervention of vessels originating from a tortuous aortic arch, which uses guide wires that used to enable the catheters accessing the left or right carotid arteries (CA). Also disclosed is the use of two independent catheters or a catheter and snare wire within a single sheath, as well as the implementations, associated problems and corrective solutions to the identified problems. Further additional uses of the bifurcated catheter / dual catheter, for access to and treatment of other exemplary tortuous locations where stability of the procedural catheter would make a difference are also disclosed in the current application.

An embolic protection device and medical procedure for positioning the device in the aortic arch is disclosed. The device and method effectively prevent material from entering with blood flow into side branch vessels of the aortic arch. The device is a collapsible embolic protection device devised for temporary transvascular delivery to an aortic arch of a patient, wherein the device has a protection unit that comprises a selectively permeable unit adapted to prevent embolic material from passage with a blood flow into a plurality of aortic side branch vessels at the aortic arch. The protection unit is permanently attached to a transvascular delivery unit at a connection point provided at the selectively permeable unit, and a first support member for the protection unit that is at least partly arranged at a periphery of the selectively permeable unit. In an expanded state of the device, the connection point is enclosed by the first support member or arranged at said support member.

A ventricular assist device includes a pump such as an axial flow pump, an outflow cannula connected to the outlet of the pump, and an anchor element. The anchor element is physically connected to the pump, as by an elongate element. The pump is implanted within the left ventricle with the outflow cannula projecting through the aortic valve but desirably terminating short of the aortic arch. The anchor element is fixed to the wall of the heart near the apex of the heart so that the anchor element holds the pump and outflow cannula in position.

A guide wire (1) to assist percutaneous endovascular deployment which has zones of varying stiffness. An elongate central zone (3) of high stiffness, a proximal zone (4) of transition from high stiffness to semi-stiffness and a distal zone (5) of transition from high stiffness to being relatively flexible. The distal zone (5) has three zones, a semi stiff zone (11) adjacent the central zone, a transition zone (13) being of flexibility of from semi-stiff extending to flexible and a tip zone (15) being of high flexibility. The distal tip has a small J curve (16) to ensure that it is atraumatic in vessels and to prevent damage to the aortic heart valve. The distal zone (5) can also have a large curve to assist with anchoring the guide wire into the aortic arch.

The invention discloses a branching type aortal vascular stent system comprising an aortal vascular stent and three branch arterial vascular stents, wherein a concave part is formed in the middle section of the aortal vascular stent, and provided with three side holes; and the three branch arterial vascular stents are separately mounted in the three side holes. The branching type aortal vascular stent system is capable of isolating aortal lesion involving the aortic arch and the ascending aorta, reestablishing the blood flow of the branch artery and avoiding the customization of the stent; and the branching type aortal vascular stent system is suitable for batch production and can be used for emergency operations.

A new apparatus, algorithm, and method (all called Invention) are introduced herein to support navigation and placement of an intravascular catheter using the electrical conduction system of the heart (ECSH) and control electrodes placed on the patient's skin. According to the present Invention, an intravascular catheter can be guided both in the arterial and venous systems and positioned at different desired locations in the vasculature in a number of different clinical situations. The catheter is connected to the apparatus using, for example, sterile extension cables, such that the apparatus can measure the electrical activity at the tip of the catheter. Another electrode of the apparatus is placed for reference on the patient's skin. In one embodiment of the present Invention, a control electrode is placed on the patient's chest over the manubrium of the sternum below the presternal notch. In this case, if a catheter is inserted in the venous system, for example in the basilic vein, the Invention will indicate if the tip of the catheter navigates from the insertion point in the basilic vein into the subclavian vein on the same side, into the subclavian vein counter laterally, into the jugular vein, into the superior vena cava, into the cavoatrial junction (CAJ), into the right atrium (RA), into the right ventricle (RV), or into the inferior vena cava (IVC). For the same location of a control electrode, if a catheter is inserted in the arterial system, the Invention will indicate when the tip of the catheter is navigating into the arch of the aorta, into the right coronary artery, into the left circumflex artery, or into the left ventricle (LV). In another embodiment of the present Invention, a control electrode can be placed on the sternum over the xiphoid process. In one embodiment of the present invention, a catheter can be inserted in the arterial systems by arterial radial, brachial or axillary access. In another embodiment of the present Invention, a catheter may be inserted into either the arterial or the venous systems by femoral or saphenous access. In one aspect of the present Invention, navigation maps are introduced for different locations in the vasculature which allow for easy identification of the location of the catheter tip. In another aspect of the present Invention, a novel algorithm is introduced to compute a navigation signal in real time using electrical signals from the tip of the catheter and from control electrodes. In another aspect of the present Invention, a novel algorithm is introduced to compute in real time navigation parameters from the navigation signal computes according to the present Invention. In another aspect of the present Invention, a method is introduced which makes use of the navigation signal to allow for placing an intravascular catheter at a desired location in the vasculature relative to the ECSH and to the control electrodes placed on the skin. In another aspect of the present Invention, the electrical signals obtained from control electrodes and from the tip of the catheter may be generated by the natural ECSH, e.g., the sino-atrial node (SAN), by artificial (implanted) pacemakers or by electrical generators external to the body. In yet another aspect of the Invention, an apparatus is introduced which supports data acquisition required by the computation of a navigation signal according to the present Invention.

A collapsible, transluminally deliverable embolic protection device (200) for temporarily positioning in the aortic arch is disclosed. The device is connectable to a transluminal delivery unit (130) extending proximally from a connection point (131). The device has a frame with a periphery, and a blood permeable unit within said periphery for preventing embolic particles from passing therethrough into side vessels of said aortic arch to the brain of a patient. Further, the device has at least one tissue apposition sustaining unit, not being a delivery shaft of said device, for application of a force offset to said connection point at said device, such as at said periphery, towards an inner wall of said aortic arch when said device is positioned in said aortic arch, such that tissue apposition of said periphery to an inner wall of said aortic arch is supported by said force. In addition related methods are disclosed.

A catheter adapted for placement in the ascending aorta comprises a central catheter mechanism and a balloon structure or other occluding structure at its distal end. The catheter may be placed over the aortic arch such that the balloon structure is placed in the ascending aorta just above the Sinus of Valsalva and coronary ostia. Once in place, the balloon structure is inflated to control blood flow through the aorta during aortic valve ablation and replacement protocols.

An endoluminal tubular prosthesis for use in an open surgical repair comprises a tubular graft having a longitudinal axis, a first tubular section having a plurality of self-expanding stents and extending along the longitudinal axis and a second stent-less tubular section extending from the first tubular section and along the longitudinal axis. The tubular prosthesis can include a plurality of tubular branching members branching therefrom for treating branched arteries without obstructing them, such as the branches from the aortic arch.

The invention provides a pre-bent aortic membrane-covered stent and a manufacturing method thereof. The pre-bent aortic membrane-covered stent is characterized by consisting of a metal stent and a covering membrane, wherein the metal stent comprises a bent keel and a plurality of Z-shaped wavy stents. By the pre-bent aortic membrane-covered stent, elastic straightening force generated after the conventional stent is passively bent on bent parts such as an aortic arc part and stress formed by the elastic straightening force can be eliminated, and newly-generated cleavages of aorta caused by the stent can be reduced and prevented.

A vessel protector for capturing or filtering material in the aortic arch includes at least one shield formed in a planar or three-dimensional shape. The shield includes a body formed from a filtering material and may be formed of a shape memory material. The shield may alternate between a collapsed configuration for delivery and an expanded configuration during use. A catheter may be used to deliver the vessel protector into the aortic arch.

The invention discloses an aortic-arch covered stent-graft, which comprises an aortic stent-graft and three branch artery stent-grafts, wherein a sunk part is arranged in the aortic stent-graft and comprises a left-side wall close to a proximal end, a right-side wall far away from the proximal end and a bottom wall for connecting the left-side wall with the right-side wall; two openings are arranged on one side wall in the left-side wall with the right-side wall of the sunk part, and one or two openings are arranged in the other side wall; an inner chimney graft with a caliber comparative with the openings is fixedly arranged in each opening; and the branch artery stent-grafts are respectively arranged in the chimney grafts. The stent-graft system with the structure can isolate aortic lesions involving the aortic arch and the ascending aorta and reconstruct the blood flow of branch arteries, is suitable for various normal and changing blood vessels, has a wide range of application, avoids customized stents, and can be in mass production. The time is effectively saved, and the operation is easy.

Embodiments of the present invention provide apparatus and methods for embolic filtering during percutaneous valve replacement and repair procedures. Under one aspect, an apparatus comprises a sheath and a filter. The sheath has proximal and distal ends and a lumen therebetween. The distal end may be introduced into the aortic arch via the peripheral arteries and ascending aorta, while the proximal end may be disposed outside of the body. The lumen permits percutaneous aortic valve replacement or repair therethrough. The filter has a frame with an inlet and an outlet and an emboli-filtering mesh attached to the frame. The inlet is substantially spans the aortic arch in a region between the aortic valve and the great arteries. The outlet is coupled to the distal end of the sheath without leaving any gaps through which emboli could pass and without obstructing the lumen at the distal end of the sheath.

Medical device for embolic protection in an aortic arch, comprising a catheter having a shaft and a distal end portion of the shaft, an expandable embolic protection device having a filter membrane and a frame. The frame comprises a frame loop and an elongated frame shaft having a distal end portion connected to the frame loop in a connection point, in its expanded state the frame loop spans said filter membrane and bending means to bend the distal end portion of the catheter and / or the distal end portion of the frame shaft. The medical device comprises a protective state in which the distal end portion of the catheter is bent, the embolic protection device is expanded, the frame shaft extends in a longitudinal direction of the bent distal end portion and the expanded frame loop being completely positioned distally of the connection point.

The invention discloses a biomechanical experiment simulation device for implantation of intravascular stent, which consists of an artificial cardiovascular system, an artificial blood and pulsatile blood flow field control system and a mechanical experiment observation device. The upper part of a liquid storage box of the artificial cardiovascular system is soaked in a silica gel ventriculus sinister model geometrically similar to the ventriculus sinister; the inlet end of the silica gel ventriculus sinister model is connected with the open liquid storage box through a silica gel hollow round ball simulating the right atrium; the outlet end of the silica gel ventriculus sinister model is connected with an aortic arch model; a microcomputer of the artificial blood and pulsatile blood flow field control system is connected with a power amplifier, a linear step motor and a piston in turn; and artificial blood with similar blood viscosity and specific gravity and containing simulated thrombus particles polystyrene microspheres is arranged in a closed-loop blood flow field model. Through the device, a simulated operation for stent implantation can be effectively and visually preformed between the clinical experiments and animal experiments on the intravascular stent, and effective biochemical evaluation on the flexibility, strength and stability of the stent can be realized.

The invention relates to a body anti-corrosive preservation solution. The raw materials in percentage by weight of the preservation solution are: 10 to 40 percent of glycerol, 10 to 70 percent of ethanol, 1 to 20 percent of metacetonic acid, 0.1 to 20 percent of hexamethylene tetramine, 0.2 to 10 percent of 5-chloro-2-methyl-4-isothiazoline-3-ketone, 0.1 to 1 percent of peppermint oil and the balance being water. The application mode of the preservation solution comprises the following steps: the anti-corrosive preservation solution is injected into the digestive system of a body from the oral cavity or the nose and the throat of the body; the anti-corrosive preservation solution is injected through an aortic arch, a brachial artery or a femoral artery; and the anti-corrosive preservation solution can also be used to wipe the surface of a body by a tampon dipped in the preservation solution. The body anti-corrosive preservation solution is nontoxic and harmless to an operator and is easy to operate; moreover, the preservation solution has no influence on the environment and excellent anti-corrosive effects, and can ensure that a body maintains a natural state and softness in a natural state (at room temperature) for 5 to 12 days. In addition, the preservation solution can be used repeatedly and has a simple preparing method, easily obtained raw materials and strong maneuverability; moreover, the preservation solution has convenient practical application and is propitious to popularize and use.

Advantageous instruments, assemblies and methods are provided for undertaking surgical procedures (e.g., cardiovascular interventional procedures). The present disclosure provides advantageous devices, assemblies and methods in the field of cardiac surgery and interventional cardiology procedures. Advantageous protection assemblies / devices (e.g., aortic arch embolic protection assemblies / devices) and related methods of use are provided. The present disclosure relates generally to embolic protection devices for use in the aortic arch to protect the distal vasculature during cardiac surgery and interventional cardiology procedures. An exemplary embolic protection device can take the form of an expandable / inflatable bladder member in a curved tube shape. The present disclosure provides advantageous (embolic) protection devices / assemblies, systems incorporating such devices / assemblies, and methods of use of such devices / assemblies for the benefit of such surgical practitioners and their patients.