The invention discloses a processing method of African daisy and echinacea purpurea health-care powder. The African daisy and echinacea purpurea health-care powder takes African daisy and echinacea purpurea as main raw materials, and is processed by the following steps: raw material treatment, compound enzyme treatment, preparation, homogenization, degassing, sterilization, vacuum concentration, sublimation drying, crushing, filtration, packaging and the like. The African daisy and echinacea purpurea health-care powder processed by the method takes the African daisy and the echinacea purpurea which have extensive sources as the raw materials, the cost is reduced, furthermore, utilization rate and economic value of the African daisy and the echinacea purpurea are also increased, by compound enzyme treatment, nutrient substances in the African daisy and the echinacea purpurea can be fully separated out, the utilization rate and the nutritional value of the African daisy and the echinacea purpurea are increased, the nutrient substances of the finished health-care powder can be enriched, the synergy is obvious, the finished health-care powder is granular powder, can be placed in water to obtain beverage, and can also be added with a proper amount of water to obtain nutritional paste after stirring, eating modes are diversified, and effects of clearing away heat and removing toxic substances, promoting blood circulation and dispelling blood stasis, reducing swelling and alleviating pain and the like are achieved.