The invention discloses a degradable medical hemostatic adhesion-resistant material and a preparation method thereof. The invention uses chitosan or derivatives thereof and transparent sodium hyaluronate as main raw materials, adopts methods, such as spray drying, self lamination assembly, and the like to prepare microspheric and gel-type hemostatic adhesion-resistant materials, and medicines and activated substances capable of stimulating hemostasis and antiphlogosis can be compounded and added in the preparation process. The material has high water absorption rate, can rapidly arrest bleeding to form an aquagel protective layer on a wound surface, has favorable tissue adhesiveness, adhesion resistance and bacterinertness, can suit a wound in an irregular shape, truly fully covers the wound surface to fully take the aims of arrest bleeding, resisting adhesion and stimulating wound surface healing, has remarkable postoperative hemostatic adhesion-resistant effects while being used for ear-nose-throat department operations, is convenient to use and brings little pain to patients.