35results about How to "Effective mechanical support" patented technology

The invention discloses a Zn-Li series zinc alloy as well as a preparation method and application thereof. The Zn-Li series zinc alloy comprises Zn and Li; and based on weight percent, the mass percent content of the Li in the zinc alloy accounts for 0 to 30%, but not including 0. The preparation method of the Zn-Li series zinc alloy comprises the following steps: (1) mixing the Zn and the Li to obtain a mixture; (2) treating the mixture according to the following step a) or step b) and then cooling the mixture to obtain the zinc alloy: a) under the protection of a CO2 and SF6 atmosphere, carrying out smelting or sintering on the mixture; and b) under the protection of a vacuum atmosphere, dissolving hydrogen gas into the mixture and carrying out the smelting. The zinc alloy prepared by the preparation method disclosed by the invention has an excellent mechanical property and can provide a long-term effective supporting force in vivo; and the zinc alloy has excellent cellular compatibility, blood compatibility and tissue and organ compatibility and can be used for preparing biomedical implant materials.

The invention provides a method for achieving eutectic soldering of chips. The method comprises the steps of a, compressible areas in the chips are determined, and a photoetching mask panel is manufactured; b, conducting adhesives in the compressible areas of the chips are removed through a photoetching develop method on a gilded ceramic wafer; c, ball points, used as protruding points, are planted at the position, where the adhesives are removed, on the ceramic wafer through a gold ball bonding method; d, the ceramic wafer is cut into small ceramic wafers consistent with the chips in size through a gear cutting method; e, a tool locating clamp is manufactured according to the shapes of cavities to be welded, and a small ceramic wafer pressing block clamp with gold protruding points makes contact with non-circuit areas of the chips through the protruding points; f, a pressing block is arranged on the small ceramic wafer pressing block clamp, and vacuum compressible soldering of the chips is indirectly achieved. The gilded ceramic wafer is used as the base material, the mature photoetching technology and the ball-bonding ball planting technology are used for manufacturing the protruding points to provide effective mechanical support for soldering, and the method is wide in application range.

The invention discloses a Zn-Li-Mg-system zinc alloy and a preparation method and application thereof. The zinc alloy comprises, by weight, 0-1% of Li, 0-1% of Mg and the balance Zn, wherein the masspercents of Li and Mg are not zero. The zinc alloy prepared by the preparation method is excellent in mechanical performance, can provide long-term and effective supporting force in a body, has excellent cellular and blood compatibility, and can be applied to preparation of biomedical implants.

The invention discloses a Zn-Li-Mn-based zinc alloy and a preparation method and application thereof. The Zn-Li-Mn-based zinc alloy comprises, by mass, greater than 0 and less than or equal to 1% of Li, greater than 0 and less than or equal to 1% of Mn and the balance of Zn. The Zn-Li-Mn-based zinc alloy has excellent mechanical properties, can provide long-term effective support in the human body, has excellent cell compatibility and blood compatibility and can be used for preparation of biomedical implants.

The invention discloses a Zn-Mg1Ca series zinc alloy and preparing method and application of Zn-Mg1Ca series zinc alloy. The zinc alloy comprises Zn and Mg1Ca, wherein the mass percent of Mg1Ca in the zinc alloy ranges from 0 to 10% but not includes 0. The zinc alloy further comrpsies a microelements which are at least one of silicon, phosphorus, lithium, silver, tin and rare earth elements. The mass percent of the microelements ranges from 0 to 3% but not includes 0. The mechanical property of the Zn-Mg1Ca series zinc alloy meets the requirement for strength and toughness of medical implant materials, the Zn-Mg1Ca series zinc alloy is free of cytotoxicity on endothelial cells and bone-forming cells, can inhibit smooth muscle cell proliferation and has good tissue compatibility and blood compatibility, meanwhile, the Zn-Mg1Ca series zinc alloy can also be regulated to be degraded by body liquid, metal ions which are dissolved out can be absorbed and utilized by an organism or metabolized to be discharged out of the body, and the Zn-Mg1Ca series zinc alloy has good antibacterial performance and can be applied to preparation of medical implants.

The invention relates to a bionic artificial bone scaffold and a preparation method thereof. The method comprises the following steps: preparing material solutions A and B; utilizing an electrostatic spinning method to respectively prepare the material solutions A and B into a central channel layer and a peripheral column layer of a scaffold, wherein nanometer fibers in the central channel layer are in same spiral directions and the fibers in two adjacent nanometer fiber layers in the peripheral column layer are in opposite spiral directions; micro-level finely simulating a three-dimensional microenvironment of an osteon; hierarchically adding growth factors, supplying a differential inducing environment to seed cells BMSCs and constructing the bionic artificial bone scaffold with vascularizing tissues in the central channel layer and bone tissues in the peripheral column layer. The staggered orientation of the nanometer fibers in the scaffold can greatly enhance the structural stability; effective mechanic support is supplied to a bone defect part; the mutually connected network frame thereof is beneficial to cell permeation growth and blood vessel and nerve growth and also is convenient to transfer nutrient substances and metabolic wastes; the bionic artificial bone scaffold has ideal popularization and application values in the fields of biomedical materials and tissue engineering.

The invention provides a gas chamber structure for gas sensing and a manufacturing method of the gas chamber structure. The gas chamber structure comprises an outer wrapping layer (1), a reflection layer (2) and a hollow core structure (3). The outer wrapping layer is located on an outermost layer, and the outer wrapping layer is a polymer outer wrapping layer. The reflection layer is an omni-directional reflection layer, and the omni-directional reflection layer is located on the inner side of the polymer outer wrapping layer. The inner side of the omni-directional reflection layer is provided with the hollow core structure, and the hollow core structure is a hollow channel for light and gas transmission. The gas chamber structure provided by the invention can solve the problems that an existing metal gas chamber is heavy, excessively large in size and difficult to couple and cannot be microminiaturized, and overcome the shortcomings that an existing optical fiber type gas chamber ispoor in mechanical performance, weak, single in material and incapable of covering an infrared wave band. Meanwhile, the processes of a thermal evaporation method, a thin film winding method, a hot drawing method and a coating method are used for preparing the flexible, low-loss and easy-to-couple microminiaturized gas chamber structure for gas sensing.

The invention provides a ligament bracket, a shaping method of the ligament bracket, and ligament implanting materials formed from the ligament bracket. The ligament bracket comprises a core part anda sheath part, wherein the core part is a threadlike or bunchy suture formed from biologic degradable high molecular polymers, the sheath part is formed through twirling and twisting biodegradable electrospun nanofiber membranes to closely wrap and be fixed outside the suture, and two ends of the suture extend from two ends of the sheath part to form a first traction line part and a second traction line part. According to the ligament bracket disclosed by the invention, by a twirling and twisting method, the electrospun nanofiber membranes closely wrap the outside of the suture, higher positive pressure is produced between fibers, tangential friction is enlarged, the ligament bracket has higher tensile violence in the axis direction, and besides, not less than two ligament brackets can bedoubled and twisted or knitted to form the ligament implanting materials having better tensile violence. Compared with the prior art, the ligament bracket can provide more effective mechanical supportto maintain stability of joints, and besides, quick scaleable preparation is facilitated.

The invention relates to the technical field of graphene materials and particularly relates to a transparent conductive composite film comprising a graphene film and a poly-p-xylylene film, wherein the poly-p-xylylene film is arranged on one surface of the graphene film. The transparent conductive composite film has the beneficial effects that the transparent conductive composite film is provided; the graphene film is supported by the poly-p-xylylene film, so that the tight molecular contact between the poly-p-xylylene film and graphene can be realized; and an effective mechanical supporting effect on graphene is taken under pi-pi coupling action, so that the thermal vibration of graphene can be remarkably inhibited, furthermore, the electrical property of graphene is stabilized, and the service performance of graphene is greatly improved.

The invention provides a medically degradable Zn-based composite and a preparing method and application thereof. The Zn-based composite is composed of, by mass percent, 50.1 to 99.9% of zinc and 0.1 to 49.9% of microelement. The microelement comprises one or multiple of Fe, Ag, Ti and Cu. The method comprises the steps of according to the proportion, zinc powder and powder containing the microelement are mixed evenly; the mixed powder is pressed and formed at the pressure of 5 to 50 MPa, and a blank is obtained; the blank is placed in a mold to be pressurized and sintered; and the pressurizedand sintered material is subjected to heat treatment, finally, extrusion forming is carried out, and the medically degradable Zn-based composite is obtained. When the Zn-based composite is applied tothe degradable medical equipment implant, the requirement of the mechanical property can be met, and the degrading speed can be regulated.

The invention relates to a preparation method of a degradation acidity-adjustable self-enhanced polyester / ordered mesoporous degradable bone repair material as well as a product and application thereof. The self-enhanced and degradation acidity-adjustable composite material is prepared by taking a degradable polyactic acid-based ternary random copolymer as a matrix and a modified ordered mesoporeas an enhancer. The preparation method comprises preparation of a PLLA surface modified MCM-41 mesoporous silicon oxide and preparation of a polyester / PLLA-NH-MCM-41 composite material. In the productobtained by the method, the mesoporous materials are dispersed uniformly into an organic matrix, the two-phase interface compatibility is high, the mechanical property of the polyester base is greatly improved and the pH can be maintained in a neutral range in a degradation process. The obtained product can meet the requirement of clinical application. The preparation process is simple and controllable, small in adding amount of nanometer materials and easy to process and form; and the product has high mechanical strength and stable performance and can serve as a bone repair material of a weight-bearing bone part with relatively high requirements on properties and indexes.

The invention belongs to the technical field of roads and bridges, and particularly relates to a protection device for a bridge pier during tide ebbing and flowing and a construction method. The protection device for the bridge pier during tide ebbing and flowing provided comprises a bridge pier fixedly arranged on a pier platform; a bridge body is arranged on the bridge pier; protection devices are arranged on the front side and the rear side of the bridge pier; each protection device comprises two side protection plates fixedly arranged on a protection body; the two side protection plates extend outwards in a radial shape; an included angle is formed between the two side protection plates; and one ends of the two side protection plates are in butt joint together or the extension lines ofthe two side protection plates intersect. According to the protection device for the bridge pier during tide ebbing and flowing and the construction method, the protection devices are arranged at thefront side and the rear side of the bridge pier, and can block and distribute rising and falling seawater during tide ebbing and flowing, so that the safety of a bridge is protected, and the servicelife of the bridge is prolonged.

The present invention proposes a chip eutectic welding method, comprising the following steps: step (a), determining the size of the L-shaped ceramic positioning fixture according to the size of the gasket; step (b), using a laser machine to cut the corresponding size L-shaped ceramic positioning fixture; step (c), in the process of positioning the chip, first adopt the L-shaped ceramic positioning fixture to fix the gasket, then put the soldering piece on the gasket, and finally put the chip on the soldering piece; step (d) After the chip is fixed by the positioning fixture, put it into the vacuum eutectic furnace and use the welding tool for eutectic welding. In the chip eutectic welding method of the present invention, the L-shaped ceramic positioning fixture is prepared by a laser machine, which effectively solves the problem of misalignment between the chip and the pad during eutectic welding. The method is simple, low in cost, and strong in feasibility; Ceramics are used as the base material, which can provide effective mechanical support and have a wide range of applications.

The invention belongs to the technical field of road bridges, and particularly relates to a defense device capable of achieving protective effect on bridge piers and a construction method. The defensedevice capable of achieving protective effect on the bridge piers provided by the invention comprises a defense body arranged at the upstream position of each bridge pier, wherein the defense body comprises a protective plate; a plurality of exploding devices towards a water flow direction are arranged on the protective plate; center positions of pressure discs in the exploding devices are provided with firing pin bins; firing pins capable of moving downwards are arranged in the firing pin bins; disc type springs for supporting the pressure discs are arranged in detonating shells; and the lower sides of the firing pins are equipped with detonators for detonating high explosives. Drifting objects which drift down from middle and upper reach of a river are blocked and distributed, and exploding devices can explode blocked large-size objects, so that the purposes of prolonging the service life of a bridge and guaranteeing bridge safety are realized.

The invention relates to preparation of polyester / periodic mesoporous bone-filling composite material with a fluorescently-labeled degradation rate, a product and application. The preparation comprises the steps of firstly, synthesizing rare-earth periodic mesoporous nanoparticles with fluorescence performance, then, subjecting the rare-earth periodic mesoporous nanoparticles to chemical modification by taking poly-L-lactic acid with low molecular weight as a modifier, and finally, adding the modified nanoparticles into a polyester matrix by a solution blending method. The invention further provides the product obtained by the method and application of the product in bone restoration as a composite bone filling material. The fluorescent mesoporous material obtained by the method provided by the invention is uniformly dispersed in an organic matrix, mechanical properties of a polyester are improved greatly, and the degradation behavior of the composite bone filling material can be monitored in real time. The preparation process is simple, and the composite bone filling material can serve as a bone filling material of load bearing bone parts with relatively high performance index requirements. The obtained composite material can meet the requirements of clinical application.

The invention discloses a dental implant preparation method. The method comprises the following steps: firstly, forming a hole or a groove in a dental implant body by the aid of various processing methods; secondly, building a cylindrical projection, a spherical projection or other stereoscopic shapes in the hole or the groove by the aid of additional material manufacturing technologies. A locking function is formed among an implant and bone tissues, the ideal space structures for growing new bones can be provided, attachment and proliferation abilities of bone tissue cells are improved, excellent bone combination is achieved, convergence among the dental implant and autologous tissues is improved, and the dental implant effectively plays a role in a human body for a long time, is excellent in mechanical property and high in mechanical strength, can effectively reduce stress shielding and keep effective mechanical support.

The invention discloses a preparation method for a joint prosthesis thigh bone prosthesis. The method comprises the following steps of generating holes or slots on a joint prosthesis thigh bone prosthesis body via various processing methods, and building column projections, spherical projections or other stereoscopic shaped-projections in the holes or the slots via additive manufacturing technology. A lockmaking action can be achieved between implantation material and a bone tissue, so an ideal spatial structure can be provided for growth of new bone; bone tissue cell adhesion and proliferation abilities can be improved and great bone combination can be realized; fusion property between joint prosthesis thigh bone prosthesis and self-tissues can be enhanced; the joint prosthesis can effectively play a role for long time in a human body; and the joint prosthesis thigh bone prosthesis has excellent mechanical property and high mechanical strength, can decrease stress block and maintain effective mechanical support.

The invention provides a method for achieving eutectic soldering of chips. The method comprises the steps of a, compressible areas in the chips are determined, and a photoetching mask panel is manufactured; b, conducting adhesives in the compressible areas of the chips are removed through a photoetching develop method on a gilded ceramic wafer; c, ball points, used as protruding points, are planted at the position, where the adhesives are removed, on the ceramic wafer through a gold ball bonding method; d, the ceramic wafer is cut into small ceramic wafers consistent with the chips in size through a gear cutting method; e, a tool locating clamp is manufactured according to the shapes of cavities to be welded, and a small ceramic wafer pressing block clamp with gold protruding points makes contact with non-circuit areas of the chips through the protruding points; f, a pressing block is arranged on the small ceramic wafer pressing block clamp, and vacuum compressible soldering of the chips is indirectly achieved. The gilded ceramic wafer is used as the base material, the mature photoetching technology and the ball-bonding ball planting technology are used for manufacturing the protruding points to provide effective mechanical support for soldering, and the method is wide in application range.

The invention discloses a Zn-Mg1Ca series zinc alloy and preparing method and application of Zn-Mg1Ca series zinc alloy. The zinc alloy comprises Zn and Mg1Ca, wherein the mass percent of Mg1Ca in the zinc alloy ranges from 0 to 10% but not includes 0. The zinc alloy further comrpsies a microelements which are at least one of silicon, phosphorus, lithium, silver, tin and rare earth elements. The mass percent of the microelements ranges from 0 to 3% but not includes 0. The mechanical property of the Zn-Mg1Ca series zinc alloy meets the requirement for strength and toughness of medical implant materials, the Zn-Mg1Ca series zinc alloy is free of cytotoxicity on endothelial cells and bone-forming cells, can inhibit smooth muscle cell proliferation and has good tissue compatibility and blood compatibility, meanwhile, the Zn-Mg1Ca series zinc alloy can also be regulated to be degraded by body liquid, metal ions which are dissolved out can be absorbed and utilized by an organism or metabolized to be discharged out of the body, and the Zn-Mg1Ca series zinc alloy has good antibacterial performance and can be applied to preparation of medical implants.

The present invention provides a method of eutectic soldering of a chip in a big pad. The method includes the following steps: step (a), determining the size of an L-shaped ceramic location clamp according to the size of the pad; step (b), determining the size of a ceramic locating pressing block according to the sizes of the pad and the chip; step (c), cutting the L-shaped ceramic locating clamp in the corresponding size by using a laser; step (d), cutting the ceramic locating pressing block in the corresponding size by using a grinding wheel cutting machine; step (e), during the process for locating the chip, first fixing the pad by using the L-shaped ceramic locating clamp, then putting the ceramic locating pressing block into the pad, and finally putting a soldering lug and the chip onto the pad; and step (f), after fixing the chip by the locating clamp, putting the chip into a vacuum eutectic furnace to perform eutectic soldering by using a soldering fixture. The method effectively solves a problem of dislocation between the chip and the pad, and the method is easy, and has a low cost and a high feasibility.

The invention belongs to the technical field of roads and bridges, and in particular relates to a protective device at the upstream position of a bridge pier and a construction method. The invention provides a protection device arranged at the upstream position of the pier, which includes the pier fixed on the abutment, the pier is provided with a bridge body, and a protection device is provided at the upstream position outside the pier, and the protection device includes a pier fixed on the protection body The two side guards on the top, the two side guards extend radially outward, an angle is provided between the two side guards, and one ends of the two side guards are butted together or their extension lines intersect. The invention is arranged at the upstream position of the pier, and can block and divert the flood or mud flow from the upstream of the river. The process of the invention is simple and convenient to install, and can realize the purpose of protecting the safety of the bridge and improving the service life.

The invention relates to an artificial spinal canal for preventing spinal nerve compression. The artificial spinal canal comprises an artificial spinal canal body, a transverse connector and a fixingdevice, wherein the artificial spinal canal body is connected with the fixing device through the transverse connector. The artificial spinal canal for preventing spinal cord nerve compression has theadvantages that the artificial spinal canals suitable for different segments are designed according to the shape and size of the spinal canal of different segments of the human spine, the artificial spinal canal is subjected to one-staged placement around a dural sac of the corresponding segment together after tumor tissue around the dural sac is subjected to excison by posterior spinal operation,the artificial spinal canal is finally fixed with the fixing device by the transverse connector for stabilization, compression on the dural sac and spinal cord nerves due to tumor recurrence, scar hyperplasia and the like can be effectively prevented in 360 degrees by the support function of the artificial spinal canal, and adhesion between the surrounding scar tissue, the dural sac and nerve roots can also be effectively prevented.

The invention discloses a rod-system pore structure for an orthopedic implant. The rod-system pore structure comprises a plurality of structural units, wherein each structural unit is formed by four rod pieces according to specific spatial positions; the structural units are combined into a three-dimensional space aperture structure system in a transformation or duplication way; the four rod pieces of each structural unit comprise a first rod piece, a second rod piece, a third rod piece and a Z rod piece; the rod-system aperture structure forms a specific shape according to actual clinical needs to form the orthopedic implant. The rod-system pore structure has structural characteristics similar to those of the bone trabecula of a human body, and is high in porosity, and an ideal spatial structure can be provided for the growth of new bones; in terms of mechanical performance, the rod-system pore structure is low in structural rigidity and strong in mechanical strength, stress shielding can be well reduced, and effective mechanical support can be maintained; the orthopedic implant formed by the rod-system pore structure has high mechanical performance and bone conduction and bone induction properties, and is widely applied to the clinical use of maintenance, support, repair and the like of human bones.

The invention discloses a Zn-Li series zinc alloy as well as a preparation method and application thereof. The Zn-Li series zinc alloy comprises Zn and Li; and based on weight percent, the mass percent content of the Li in the zinc alloy accounts for 0 to 30%, but not including 0. The preparation method of the Zn-Li series zinc alloy comprises the following steps: (1) mixing the Zn and the Li to obtain a mixture; (2) treating the mixture according to the following step a) or step b) and then cooling the mixture to obtain the zinc alloy: a) under the protection of a CO2 and SF6 atmosphere, carrying out smelting or sintering on the mixture; and b) under the protection of a vacuum atmosphere, dissolving hydrogen gas into the mixture and carrying out the smelting. The zinc alloy prepared by the preparation method disclosed by the invention has an excellent mechanical property and can provide a long-term effective supporting force in vivo; and the zinc alloy has excellent cellular compatibility, blood compatibility and tissue and organ compatibility and can be used for preparing biomedical implant materials.

The invention discloses a Zn-Mn series zinc alloy and a preparing method and application thereof. The Zn-Mn series zinc alloy comprises Zn and Mn, wherein by weight percent, the mass percent of Mn in the zinc alloy ranges from 0% to 30%, however the mass percent of the Mn cannot be 0. The preparing method comprises following steps: firstly, Zn and Mn are mixed, and a mixture is obtained; secondly, the mixture is treated according to the step of a or b, cooling is carried out, and the zinc alloy is obtained, wherein under the CO2 and SF6 atmosphere protection, the mixture is smelted or sintered, and under the vacuum atmosphere protection, hydrogen is dissolved in the mixture to be smelted. The prepared Zn-Mn series zinc alloy is excellent in mechanical property, long-term effective mechanical support is provided in the machine body, the excellent cellular biocompatibility, blood compatibility and tissue and organ compatibility can be achieved, and the alloy can be used for preparing of biomedical implant materials.

The invention relates to the preparation, product and application of a polyester / periodic mesoporous bone filling composite material whose degradation rate can be fluorescently marked. Firstly, rare earth periodic mesoporous nanoparticles with fluorescent properties were synthesized, then the rare earth periodic mesoporous nanoparticles were chemically modified with low molecular weight poly-L-lactic acid as a modifier, and finally added to the polyester matrix by solution blending middle. The product obtained by the above method and the application of the product as a composite bone filling material in bone repair are also provided. The fluorescent mesoporous material obtained by the method of the invention is evenly dispersed in the organic matrix, the mechanical properties of the polyester base are greatly improved, and the degradation behavior of the composite bone filling material can be monitored in real time. The preparation process is simple, and it can be used as a bone filling material for load-bearing bone parts with high performance index requirements. The obtained composite material can meet the requirement of clinical application.

The invention discloses a graphene oxide-butyronitrile latex composite foam material and a preparation method thereof, and belongs to the technical field of composite material preparation, and the preparation method comprises the following steps: (1) uniformly mixing a graphene oxide dispersion liquid and butyronitrile latex to prepare a mixed dispersion liquid, and adjusting the pH value of the mixed dispersion liquid; (2) freezing the mixed dispersion liquid and then performing vacuum freeze drying to obtain a composite foam matrix material; and (3) heating and crosslinking the composite foam matrix material to prepare the graphene oxide-butyronitrile latex composite foam material. The graphene oxide and the butyronitrile latex are fully dispersed and mixed by controlling the electrostatic interaction between the graphene oxide and the butyronitrile latex, so that the phenomenon of uneven agglomeration and dispersion of the graphene oxide is improved; by controlling the concentration and freezing temperature of the graphene oxide solution, the sizes and structures of the cells are regulated and controlled; by controlling the heating temperature and the heating time, the graphene oxide is decomposed at high temperature to release free radicals to initiate high-temperature self-vulcanization crosslinking of the butyronitrile latex, and it is guaranteed that the composite foam has high compression strength.

The invention belongs to the field of medical bone repair materials and preparation thereof, and relates to a functional bionic porous titanium alloy femoral head supporting rod and a preparation method thereof. The functional bionic porous titanium alloy femoral head supporting rod comprises the following components: titanium alloy and magnesium. The preparation method comprises the following steps of: preparing the femoral head supporting rod which is matched with the mechanical strength and the elastic modulus of a human bone and has a bone trabecula bionic porous structure by taking the titanium alloy as a raw material by adopting an Electron Beam Melting (EBM) technology; and then preparing high-purity functional magnesium coatings on the inner surface and the outer surface of the porous titanium alloy by adopting a multi-arc ion coating technology. The matter being worth emphasizing is that the material can be used for preparing the femoral head supporting rod and bone repair materials at other parts due to good mechanical strength, good angiogenesis effect and good osteogenesis promoting effect. The preparation method of the material is simple, convenient and feasible, is friendly to the human environment, can be produced in batches, and has a good application prospect in the field of medical bone repair materials.

The invention relates to a bionic artificial bone scaffold and a preparation method thereof. The method comprises the following steps: preparing material solutions A and B; utilizing an electrostatic spinning method to respectively prepare the material solutions A and B into a central channel layer and a peripheral column layer of a scaffold, wherein nanometer fibers in the central channel layer are in same spiral directions and the fibers in two adjacent nanometer fiber layers in the peripheral column layer are in opposite spiral directions; micro-level finely simulating a three-dimensional microenvironment of an osteon; hierarchically adding growth factors, supplying a differential inducing environment to seed cells BMSCs and constructing the bionic artificial bone scaffold with vascularizing tissues in the central channel layer and bone tissues in the peripheral column layer. The staggered orientation of the nanometer fibers in the scaffold can greatly enhance the structural stability; effective mechanic support is supplied to a bone defect part; the mutually connected network frame thereof is beneficial to cell permeation growth and blood vessel and nerve growth and also is convenient to transfer nutrient substances and metabolic wastes; the bionic artificial bone scaffold has ideal popularization and application values in the fields of biomedical materials and tissue engineering.