The invention is applicable to the technical field of medicines, and provides
prunus humilis procyanidins, a preparation method and application thereof, and a
medicine; the preparation method of the
prunus humilis procyanidins comprises the following steps: preparing and depitting
prunus humilis to obtain depitted
prunus humilis; carrying out ultrasonic extraction on the
prunus humilis and an
ethanol aqueous solution at the temperature of 30-50 DEG C to obtain an extracting solution; and carrying out suction
filtration on the extracting solution, and then carrying out vacuum concentration andfreeze-
drying treatment to obtain the
prunus humilis procyanidine. The active ingredients in the prunus humilis bunge are extracted and prepared into the freeze-dried
powder, so that the
biological activity of the prunus humilis bunge can be maintained, the prunus humilis is convenient to store and transport, and the prunus humilis freeze-dried
powder has important significance in development of the prunus humilis industry and meeting of increasing large health requirements of people. In addition, the prunus humilis procyanidine has the effects of preventing
osteoporosis, maintaining a
bone structure, protecting the integrity of a bone trabecula
microstructure, improving
estrogen disorder caused by
menopause, regulating and controlling intestinal
flora metabolites of organisms and the like.