The invention relates to a bioactive degradable magnesium alloy guided bone regeneration membrane and a processing method for dense pores thereof, comprising: a barrier membrane whose shape fits the bone tissue around the defect area, the barrier membrane is divided into upper and lower parts, and the upper and lower parts of the barrier membrane It is designed to have a skeleton structure area and a regularly arranged through hole area. The arrangement rule of the through hole is dense and dense. There are no through holes at the skeleton structure, and the through hole area is a plurality of 0.5‑5mm circular areas. In the above A number of dense holes less than or equal to 0.2mm are evenly distributed in the circular area, and the spacing of the dense holes is adjusted according to the corrosion rate of the actual material used and the required corrosion effect. The barrier film also includes blind holes with a depth of 0.05mm-0.25mm, and drugs are loaded in the blind holes. The through holes of the present invention can discharge degraded gas, penetrate body fluids, nutrients, and red blood cells, and hinder the penetration of soft tissue cells; the dense holes in the through hole area mainly serve to prevent early soft tissue growth, and at the same time, the implanted At the same time, it can degrade, release magnesium ions, and play an osteogenic role; the barrier membrane is designed with a skeleton structure, and there are no through holes in the skeleton structure, which can be modified and degraded slowly to maintain the mechanical support of the barrier membrane in the process of bone repair. The invention can solve the technical problem that the material between the through holes of the existing barrier membrane is rapidly degraded, and the entire barrier membrane loses mechanical support prematurely after the through holes are connected to each other, which is not conducive to the repair of the bone defect area.