535 results about "Osseointegration" patented technology

An implant for surgical insertion into tissue of a patient includes a microgeometric, repetitive pattern, in the form of a multiplicity of alternating ridges and grooves, each having an established width in a range of about 2 to about 25 microns, and an established depth in a range of about 2 to about 25 microns, each groove having a base and a wall; and a microgeometric random surface pattern, applied over the repetitive surface pattern, defining a multiplicity of micro-pits having dimensions in a range of about 0.1 to about 4 microns.

A dental prosthesis for periodontal integration is disclosed. Furthermore a customized dental prosthesis for osseointegration is disclosed having a first manufactured portion shaped to substantially conform to the three-dimensional surface of a root of a tooth to be replaced and a second manufactured portion shaped to substantially conform to the three-dimensional surface of a crown of a tooth to be replaced. Furthermore a customized manufactured splint is disclosed to position and fixate a tooth-shaped prosthesis. Furthermore a CAD / CAM based method of and a system for manufacturing a customized dental prosthesis replacing an extracted tooth is disclosed, where the extracted tooth is scanned regarding its three-dimensional shape and substantially copied using (a) an imaging system in-vitro like a 3D scanner or in-vivo like a cone beam CT system, (b) CNC machinery and (c) biocompatible material that is suitable to be integrated into the extraction socket and at least partially adopted by the existing tissue forming the socket.

A sub-periosteally implantable prosthesis support structure for a fixed or detachable dental prosthesis includes a framework fitted to and generally conforming to the inner and outer contours of the bony ridge structures of a person. The framework is configured to provide a space extending generally normal to the bony ridge structure to an apex to provide space for subsequent bone growth. A plurality of denture support posts are distributed about the framework and depend outwardly from the apex in substantial alignment with the bony ridge structure. During the fabrication of the prosthesis support structure, a bio-compatible fine mesh screen is fixed to and spans, tent-like, the framework to substantially overlay the bone structure and the space provided for subsequent bone growth. After the support structure has been implanted, the growth of bone into the space and around the support structure is promoted to osseo-integrate the support structure with the person's bony ridge, thus providing a secure foundation for a denture or fixed dental prosthesis configured for detachable or fixed coupling with the denture support posts. The support structure may be made, partly or wholly, from either non-resorbable material, such as titanium stock and mesh, or from a resorbable material such as Vicryl TM .

Novel orthopaedic bone screws / spinal pedicle screws and implants that include coatings to help promote a structurally stable interface between the implant and the patient's bone / tissue, and methods of coating such screws and implants are provided. The implants and methodologies described involve at least a coating that facilitates osseous integration, and additionally at least one coating that either reduces the risk of infection in immunologically suppressed patients and / or for utilization in patients who have infection, but who require stabilization, or coatings that permit the use of dissimilar metals and prevent galvanic corrosive reactions.

Dental implants made at least in part of a porous tantalum material for enhancing the osseointegration of the dental implant into surrounding bone. For example, there is provided a dental implant which includes a porous tantalum portion and an outer portion having a color generally replicating the color of natural teeth. The dental implant further comprises a core portion and the porous tantalum portion at least partially surrounds the core portion. An esthetic portion is disposed at least the outer portion and the porous tantalum portion is disposed for at least partially reinforcing the esthetic portion. After implantation of the implant, bone tissue may osseointegrate into the porous tantalum portion to anchor the implant in position within the surrounding bone. Other embodiments of implants are provided, each implant including at least a portion thereof formed of porous tantalum for improved osseointegration.

A dental implant has a body with a porous metal portion for engaging bone. The porous metal portion has an outer coronal to apical height and an outer diameter. Both the height and diameter are about 4 mm to about 6 mm. This permits the implant to be placed on a jaw with a reduced bone volume.

Dental prosthesis, systems, and methods of forming and using a dental prosthesis, are provided. An example of a dental prosthesis includes a first manufactured portion shaped to substantially conform to the three-dimensional surface of a root of a tooth to be replaced and a second manufactured portion shaped to substantially conform to the three-dimensional surface of a crown of the tooth. Furthermore, customized manufactured splints to position and fixate a tooth-shaped prosthesis, are provided. Furthermore, a CAD / CAM based methods of and a systems for manufacturing a customized dental prosthesis are provided. The tooth can be scanned to determine its three-dimensional shape and substantially copied using an imaging system in-vitro like a 3D scanner or in-vivo like a cone beam CT system and CNC machinery. Biocompatible material that is suitable to be integrated into the extraction socket and adopted by existing tissue forming the socket can be manufactured or engineered.

A porous bone fixation device has a body including non-porous areas that provide superior long term fixation and osteointegration performance. The porous areas provide an in-growth surface in strategic sections such as the threaded section of the fixation device that allow substantially more contact area between in-growth surface and bone. The in-growth material is a network of interconnected porosity in a matrix of bio compatible, preferably titanium. Examples of bone fixation devices include bone screws, bone anchors, dental implants, and similar devices used to provide a fixation point in bone.

Compositions and materials for making soft suture anchors comprising materials that improve osteointegration have been developed. These compositions and materials comprise bioceramics, resorbable materials, and combinations thereof. A preferred embodiment comprises a soft suture anchor comprising a resorbable ceramic and a resorbable suture.

Custom dental prosthesis or implants each individually designed and manufactured to replace nonfunctional natural teeth positioned in a jawbone of a specific pre-identified patient are provided. An example dental prosthesis / implant includes a dental implant body having a prosthesis interface formed therein to receive an occlusally-facing dental prosthesis component. The prosthesis interface has a custom three-dimensional surface shape positioned and formed to create a form locking fit with respect to the occlusally-facing dental prosthesis component when positioned thereon.

The invention relates to a method for obtaining a surface of a titanium-based metal implant intended to be inserted into bone tissue, comprising: (a) projecting particles of aluminium oxide under pressure on the external area of the implant; (b) chemically treating the sandblasted external area of the implant with an acid composition comprising sulfuric acid and hydrofluoric acid; and (c) thermally treating the sandblasted external area of the implant by heating at a temperature of 200-450° C. for 15-120 min. The invention likewise defines a metal implant having said surface. The surface thus obtained has good micrometer-scale roughness with a suitable morphology, as well as a composition which is virtually free of impurities and a thickness which is approximately three times the thickness of conventional surfaces, which characteristics provide it with very good osseointegration properties.

An implant which includes a shaft made of a first material and having an exterior surface, and at least one thread made of a second material different from the first material, engaging the exterior surface, and extending outwardly from the exterior surface for engaging bone. After implantation of the implant, bone tissue may osseointegrate into the porous shaft to anchor the implant within the surrounding bone. The first material may be a porous metal and include tantalum while the second material is non-porous.

In alternative embodiments, the invention provides articles of manufacture comprising biocompatible nanostructures comprising PolyEther EtherKetone (PEEK) surface-modified (surface-nanopatterned) to exhibit nanostructured surfaces that promote osseointegration and bone-bonding for, e.g., joint (e.g., knee, hip and shoulder) replacements, bone or tooth reconstruction and / or implants, including their use in making and using artificial tissues and organs, and related, diagnostic, screening, research and development and therapeutic uses, e.g., as primary or ancillary drug delivery devices. In alternative embodiments, the invention provides biocompatible nanostructures that promote osseointegration and bone-bonding for enhanced cell and bone growth and e.g., for in vitro and in vivo testing, restorative and reconstruction procedures, implants and therapeutics.

Provided are a method of manufacturing a fixture of a dental implant with an improved structure in which the performance of osseointegration is excellent, spread of inflammation is reduced and a combination force between the fixture and an alveolar bone is remarkably increased, and a fixture of a dental implant manufactured by the method. The performance of osseointegration is excellent, and spread of inflammation can be reduced, and a combination between the fixture and an alveolar bone can be remarkably improved. Furthermore, the fixture of the dental implant having the above structure can be easily manufactured.

An orthopedic device adapted for implantation into a body where it contacts bone tissue is disclosed which has at least one spaced apart polarized magnetic element, at least one piezoelectric element or a combination of a polarized magnetic element and a piezoelectric element which are in direct contact with one another or are separately mounted on the implant. The piezoelectric element being at least partially embedded in a surface of the device which contacts bone tissue for the promotion of osteogenesis or osseointegration.

The invention provides a porous titanium alloy human cervical interbody fusion cage with bioactivity and a preparation method thereof. The method comprises the following steps: firstly, inputting model data into electron beam melting equipment according to a design requirement to prepare a porous titanium alloy human cervical interbody fusion cage; secondly, preparing gelatin microspheres; and immersing gelatin microsphere dry powder in an rhBMP-2 solution for gelatin coating modification, preparing a gelatin solution A in double distilled water, immersing the porous titanium alloy human cervical interbody fusion cage in the gelatin solution A, mixing the rhBMP-2 gelatin microspheres and absolute ethanol to obtain suspension B, and immersing the gelatin-coating-modified porous titanium alloy human cervical interbody fusion cage in the suspension B to prepare the porous titanium alloy human cervical interbody fusion cage internally containing an rhBMP-2 sustained-release system. The cervical interbody fusion cage prepared with the method has modulus of elasticity close to that of natural bone tissues, and the porous structure and the bioactivity factor sustained-release system inside the cervical interbody fusion cage can induce growth of new bone tissues, so that the binding problem of bone-material interfaces is solved. Therefore, the cervical interbody fusion cage has bettermechanical compatibility and bone integration capability than those of a compact material.

A composite for osteochondral defect repair includes a porous scaffold and a periosteal graft secured to a surface of the scaffold. The composite provides cartilage growth from autologous periosteum chondrogenesis. Biological resurfacing of large osteochondral defects, or a complete joint is feasible using the porous scaffold / autologous periosteal composite. The use of this composite eliminates the necessity of using normal cartilage surface as a donor site and its respective associated morbidity. In one form, the strong bone integration capacity of a porous metal (e.g., tantalum) scaffold and the high grade of integration observed from periosteal chondrogenesis into the normal cartilage eliminates the lack of chondral-chondral integration observed in the autologous osteochondral graft technique.

Dental prosthesis, systems, and methods of forming and using a dental prosthesis, are provided. An example of a dental prosthesis includes a first manufactured portion shaped to substantially conform to the three-dimensional surface of a root of a tooth to be replaced and a second manufactured portion shaped to substantially conform to the three-dimensional surface of a crown of the tooth. Furthermore, customized manufactured splints to position and fixate a tooth-shaped prosthesis, are provided. Furthermore, a CAD / CAM based methods of and a systems for manufacturing a customized dental prosthesis are provided. The tooth can be scanned to determine its three-dimensional shape and substantially copied using an imaging system in-vitro like a 3D scanner or in-vivo like a cone beam CT system and CNC machinery. Biocompatible material that is suitable to be integrated into the extraction socket and adopted by existing tissue forming the socket can be manufactured or engineered.

A bone restoration body with a composite porous structure and a preparation method of the bone restoration body. The bone restoration body comprises a porous metal bracket and an infill body with a porous structure, wherein the porous metal bracket is of a three-dimensional net structure, a plurality of pores are arranged in the inner part of the porous metal bracket, and the infill body with the porous structure is fully filled in all the pores. The preparation method combines the direct metal rapid prototyping technology and the freeze drying technology and comprises the steps of preparing the porous metal bracket by a structural design and the direct metal rapid prototyping technology, pouring uniformly-mixed polymer solution or polymer / biological ceramics mixing solution into the porous metal bracket, carrying out freezing treatment, and then forming the infill body with the porous structure through freeze drying so as to obtain the bone restoration body with the composite porous structure, wherein the infill body with the porous structure has micropore characteristics. The bone restoration body has good mechanics compatibility, can obtain good bone conduction performance and bone induction performance, improves bone integration efficiency and can be used for clinical treatment of segmental bone defect of a bearing part.

Methods and compositions are provided for the therapeutic use of Wnt proteins, for enhancing bone growth and regeneration, including repair following injury, osseointegration of implants, and the like. In some embodiments of the invention, the compositions are administered locally, e.g. by injection at the site of an injury. For certain conditions it is desirable to provide Wnt activity for short periods of time, and an effective dose will be administered over a defined, short period of time.

A temporary prosthesis for use during the osseointegration process of an installed dental implant comprises load-absorbing properties and is mountable to the implant, providing an aesthetic appearance to the implant site, while preventing or minimizing loads on the implant itself.

A dental prosthetic includes an elongate threaded implant adapted to be secured within the trabecular region of a maxilla or mandible. An abutment having a first region adapted to receive a crown and a second region adapted for coupling to the elongate threaded implant is secured to the elongate threaded implant. The abutment and elongate threaded implant extend generally along a common longitudinal axis. A compliant brace is adapted for placement between the first region of the abutment and the elongate threaded implant. The compliant brace includes first, second, and third elongate extensions capable of engaging the cortical region of the maxilla or mandible, thereby minimizing micromotion and allowing for osseointegration despite immediate installation of a crown and immediate mechanical loading. The dental prosthetic may also include an adaptor for coupling the elongate threaded implant and the abutment. Methods for implanting dental prosthetics are also described.

Disclosed herein is an implant device for osseointegration to endure weight. This implant device includes an insert-type implant inserted into an amputated end of a thighbone or a lower leg bone of a leg of a patient; a load dispersing adaptor having a cap shape, encompassing both the implant and the amputated end of the leg simultaneously at a lower end of the implant; a load support plate having a plate shape, coupled with the lower surface of the adaptor, whose diameter is widened, on which a plurality of muscle fixing holes are dispersedly formed; and a coupling screw, which couples the load dispersing adaptor with the insert-type implant at a bottom of the load dispersing plate through screw-coupling.

A transcutaneous port includes a subcutaneous port section and a bone fixation section. The subcutaneous port section has upper portion which has an axial channel and a first micro-textured external surface, and a lower portion which has therein a transverse channel connecting to the axial channel. The bone fixation section has a transosseous collar portion which has a second micro-textured external surface, and a threaded shaft portion. The first and second micro-textured external surfaces include a multiplicity of alternating microgrooves and ridges for tissue and bone integration. The transcutaneous port is surgically implanted into a site of a patient and a conductive wire is introduced from the axial channel to the transverse channel, and placed in the subcutaneous soft tissue and in contact with a neural signal source for transmitting neural signals to a prosthetic motor device.

A housing for an implantable device to be secured to a patient's bone is disclosed. The housing comprises at least one osseointegrating protuberance extending from one or more surfaces of the housing adapted to abut the patient's bone. The at least one osseointegrating protuberance is configured to be extricated from the bone subsequent to osseointegration. The housing can be used, for example, for an implantable stimulator unit of a cochlear prosthetic device.

Red light implants for delivering red light to spinal implants to enhance osteointegration.

A method of integrating bone and implant material includes drilling a hole in either one of the bone and the implant material through to a junction of the bone and the implant material by applying a laser beam to either one of the bone and the implant material and integrating the bone and the implant material by applying a laser beam to the junction through the hole drilled at the drilling.

The present invention provides a porous bioceramics for bone scaffold. The porous bioceramics according to the present invention comprises a biocompatible porous ceramic substrate having the property to thermal-decompose hydroxyapatite in contact with it; a fluorapatite (FA) inner layer formed on said porous ceramic substrate; and a hydroxyapatite (HA) outer layer formed on said fluorapatite inner layer. The insertion of FA intermediate layer can prevent the thermal reaction between ZrO2 and HA. Therefore, the present invention can provide the implant material into human body having excellent mechanical properties of zirconia as well as the biocompatibility, bioaffinity and bioactivity of HA. The present invention can also provide the implant material to promote osteoconduction and osteointegration in human body.