The invention discloses a method of making liquor by virtue of solid fermentation with bamboos as fluff. The method comprises the following steps: crushing clean bamboo products into particles with the particle size of 3-10mm, then steaming the particles of the bamboo products for 10-30 minutes, cooling, mixing the particles serving as the fluff, grains and vinasse, and carrying out solid fermentation to brew Fen-flavor bamboo wines, strong-flavor bamboo wines or soy sauce flavor bamboo wines, wherein the bamboo products are one or more of bamboo stems, bamboo leaves, bamboo branches and bamboo rhizome; and after crushing, the particle sizes of the bamboo rhizome and the bamboo stem are 8-10mm, the particle size of the bamboo branch is 5-8mm, and the particle size of the bamboo leaf is 3-5mm. According to the method disclosed by the invention, the bamboo products and the grains are used for brewing according to a certain ratio, so that the grains can be saved by 10-15 percent under the condition of the same yield of liquor; as different parts of the bamboos in different particle sizes are mixed as the fluff for brewing, the traditional hulls can be completely replaced; meanwhile, as the bamboos and the grains form a particle size gradient, fermentation and distillation of the grains are facilitated.